Paul A Sharp

Paul A Sharp

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Paul A Sharp

Paul A Sharp

Publications by authors named "Paul A Sharp"

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Zinc induces iron egress from intestinal Caco-2 cells via induction of Hephaestin: A role for PI3K in intestinal iron absorption.

Biochem Biophys Res Commun 2020 Mar 20;523(4):987-992. Epub 2020 Jan 20.

National Institute of Nutrition, ICMR, Hyderabad, India. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2020.01.023DOI Listing
March 2020

Iron and Zinc Homeostasis and Interactions: Does Enteric Zinc Excretion Cross-Talk with Intestinal Iron Absorption?

Nutrients 2019 Aug 13;11(8). Epub 2019 Aug 13.

Biochemistry Division, National Institute of Nutrition, ICMR, Hyderabad 500 007, India.

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http://dx.doi.org/10.3390/nu11081885DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6722515PMC
August 2019

Zinc induces iron uptake and DMT1 expression in Caco-2 cells via a PI3K/IRP2 dependent mechanism.

Biochem J 2019 06 11;476(11):1573-1583. Epub 2019 Jun 11.

Biochemistry Division, National Institute of Nutrition, ICMR, Hyderabad, India

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http://dx.doi.org/10.1042/BCJ20180939DOI Listing
June 2019

Curcumin and (-)- Epigallocatechin-3-Gallate Protect Murine MIN6 Pancreatic Beta-Cells Against Iron Toxicity and Erastin-Induced Ferroptosis.

Pharmaceuticals (Basel) 2019 Feb 6;12(1). Epub 2019 Feb 6.

Department of Nutritional Sciences, School of Life Course Sciences, King's College London. Franklin-Wilkins-Building, 150 Stamford Street, London, SE1 9NH, UK.

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http://dx.doi.org/10.3390/ph12010026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469157PMC
February 2019

Iron and liver fibrosis: Mechanistic and clinical aspects.

World J Gastroenterol 2019 Feb;25(5):521-538

Department of Nutritional Sciences, School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London SE1 9NH, United Kingdom.

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http://dx.doi.org/10.3748/wjg.v25.i5.521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371002PMC
February 2019

DNA methylation of hepatic iron sensing genes and the regulation of hepcidin expression.

PLoS One 2018 17;13(5):e0197863. Epub 2018 May 17.

Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197863PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5957407PMC
November 2018

Conjugated Linoleic Acid Isomers Exert Differential Effects on an Adipocyte Model of HIV-associated Lipodystrophy.

Curr HIV Res 2017 ;15(1):46-55

King's College London, School of Medicine, Diabetes and Nutritional Sciences Division, London, SE1 9NH, United Kingdom.

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http://dx.doi.org/10.2174/1570162X14666161207125948DOI Listing
February 2018

Microarray Analysis Reveals Altered Lipid and Glucose Metabolism Genes in Differentiated, Ritonavir-Treated 3T3-L1 Adipocytes.

Curr HIV Res 2016 ;14(1):37-46

Diabetes and Nutritional Sciences Division, King's College London, UK.

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http://dx.doi.org/10.2174/1570162x13666150806110238DOI Listing
August 2016

Evidence for an enhancing effect of alginate on iron availability in Caco-2 cells.

J Agric Food Chem 2012 Nov 1;60(45):11318-22. Epub 2012 Nov 1.

Department of Nutrition, Norwich Medical School, University of East Anglia, Norwich NR4 7TJ, United Kingdom.

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http://dx.doi.org/10.1021/jf3031309DOI Listing
November 2012

Basal expression of copper transporter 1 in intestinal epithelial cells is regulated by hypoxia-inducible factor 2α.

FEBS Lett 2012 Jul 7;586(16):2423-7. Epub 2012 Jun 7.

Diabetes & Nutritional Sciences Division, King's College London, London, UK.

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http://dx.doi.org/10.1016/j.febslet.2012.05.058DOI Listing
July 2012

Quercetin-iron chelates are transported via glucose transporters.

Free Radic Biol Med 2011 Apr 14;50(8):934-44. Epub 2011 Jan 14.

King's College London, London SE1 9HN, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.01.005DOI Listing
April 2011

Hypoxia inhibits hepcidin expression in HuH7 hepatoma cells via decreased SMAD4 signaling.

Am J Physiol Cell Physiol 2011 Apr 2;300(4):C888-95. Epub 2011 Feb 2.

Nutritional Sciences Division, King’s College London, United Kingdom.

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http://dx.doi.org/10.1152/ajpcell.00121.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074628PMC
April 2011

Erythropoietin regulates intestinal iron absorption in a rat model of chronic renal failure.

Kidney Int 2010 Oct 14;78(7):660-7. Epub 2010 Jul 14.

Institute of Structural and Molecular Biology, University College London, London, UK.

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http://dx.doi.org/10.1038/ki.2010.217DOI Listing
October 2010

Intestinal iron absorption: regulation by dietary & systemic factors.

Authors:
Paul A Sharp

Int J Vitam Nutr Res 2010 Oct;80(4-5):231-42

King's College London, Nutritional Sciences Division, London, UK.

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https://econtent.hogrefe.com/doi/10.1024/0300-9831/a000029
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http://dx.doi.org/10.1024/0300-9831/a000029DOI Listing
October 2010

Transferrin receptor 2 is crucial for iron sensing in human hepatocytes.

Am J Physiol Gastrointest Liver Physiol 2010 Sep 24;299(3):G778-83. Epub 2010 Jun 24.

King's College London, UK.

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http://dx.doi.org/10.1152/ajpgi.00157.2010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2950680PMC
September 2010

Quercetin is a substrate for the transmembrane oxidoreductase Dcytb.

Free Radic Biol Med 2010 May 22;48(10):1366-9. Epub 2010 Feb 22.

Department of Physiology, King's College London, Waterloo Campus, London SE1 9HN, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2010.02.021DOI Listing
May 2010

Hepcidin decreases iron transporter expression in vivo in mouse duodenum and spleen and in vitro in THP-1 macrophages and intestinal Caco-2 cells.

J Nutr 2009 Aug 23;139(8):1457-62. Epub 2009 Jun 23.

Nutritional Sciences Division, King's College London, London SE1 9NH, UK.

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http://dx.doi.org/10.3945/jn.108.102905DOI Listing
August 2009

Activated macrophages induce hepcidin expression in HuH7 hepatoma cells.

Haematologica 2009 Jun 19;94(6):773-80. Epub 2009 May 19.

Nutritional Sciences Division, King's College London, London, UK.

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http://dx.doi.org/10.3324/haematol.2008.003400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2688568PMC
June 2009

Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro.

FEBS Lett 2008 Jun 20;582(13):1901-6. Epub 2008 May 20.

King's College London, Iron Metabolism Group, Nutritional Sciences Division, Franklin-Wilkins Building, 150 Stamford Street, London SE1 9NH, United Kingdom.

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http://dx.doi.org/10.1016/j.febslet.2008.05.010DOI Listing
June 2008

Ctr1 and its role in body copper homeostasis.

Authors:
Paul A Sharp

Int J Biochem Cell Biol 2003 Mar;35(3):288-91

Centre for Nutrition and Food Safety, School of Biomedical and Life Sciences, University of Surrey, Guildford GU2 7XH, UK.

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http://dx.doi.org/10.1016/s1357-2725(02)00134-6DOI Listing
March 2003