Paul A Monach

Paul A Monach

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Paul A Monach

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Evaluation of Potential Serum Biomarkers of Disease Activity in Diverse Forms of Vasculitis.

J Rheumatol 2019 Sep 1. Epub 2019 Sep 1.

From Boston University, Boston, MA, USA; University of Arizona, Tucson, AZ, USA; University of Michigan, Ann Arbor, MI, USA; University of South Florida, Tampa, FL, USA; Mount Sinai Hospital, Toronto, Ontario, Canada; McMaster University, Hamilton, Ontario, Canada; University of Utah, Salt Lake City, UT, USA; Cleveland Clinic, Cleveland, OH, USA; University of Pennsylvania, Philadelphia, PA, USA; University of Pittsburgh, Pittsburgh, PA, USA; Johns Hopkins University, Baltimore, MD, USA; Mayo Clinic, Rochester, MN, USA; VA Boston Healthcare System, Boston, MA, USA. This work was sponsored by the Vasculitis Clinical Research Consortium. The Vasculitis Clinical Research Consortium (VCRC) is part of the Rare Diseases Clinical Research Network (RDCRN), an initiative of the Office of Rare Diseases Research (ORDR), National Center for Advancing Translational Science (NCATS). The VCRC is funded through collaboration between NCATS, and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), U54 AR057319), and has received funding from the National Center for Research Resources (U54 RR019497). Additional funding for this project included RC1 AR 058303 and P60 AR047785. Dr. Merkel reports receiving funds for the following activities: Consulting: AbbVie, AstraZeneca, Biogen, Boeringher-Ingelheim, Bristol-Myers Squibb, Celgene, ChemoCentryx, Genentech/Roche, Genzyme/Sanofi, GlaxoSmithKline, InflaRx, Insmed, Jannsen, Kiniksa; Research Support: AstraZeneca, Boeringher- Ingelheim, Bristol-Myers Squibb, Celgene, ChemoCentryx, Genentech/Roche, GlaxoSmithKline, Kypha, TerumoBCT; Royalties: UpToDate. Dr. Monach reports receiving funds for the following activities: Consulting: Celgene, ChemoCentryx. Address correspondence to Paul Monach, MD, PhD Rheumatology Section VA Boston Healthcare System 150 South Huntington Ave Boston, MA 02130. Email:

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http://dx.doi.org/10.3899/jrheum.190093DOI Listing
September 2019

Feasibility and Construct Validation of the Patient Reported Outcomes Measurement Information System in Systemic Vasculitis.

J Rheumatol 2019 Aug 1;46(8):928-934. Epub 2019 Mar 1.

From the Department of Epidemiology and Biostatistics, Faculty of Medicine, University of Iceland; Department of Rheumatology, and Centre for Rheumatology Research, University Hospital, Reykjavik, Iceland; Department of Biostatistics, Epidemiology, and Informatics, and Division of Rheumatology, and Department of Family Medicine and Community Health, and Division of General Internal Medicine, University of Pennsylvania, Philadelphia; Division of Rheumatology, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Biostatistics and Informatics, Department of Pediatrics, University of South Florida, Tampa, Florida; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Department of Rheumatology, Cleveland Clinic, Cleveland; Ohio State University Wexner Medical Center, Columbus, Ohio; Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, and Division of Pulmonology and Critical Care Medicine, Mayo Clinic College of Medicine and Science, Rochester, Minnesota, USA; Nuffield Department of Population Health, Health Services Research Unit (HSRU), and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford; Faculty of Health and Applied Sciences, University of the West of England, Bristol and School of Clinical Sciences, University of Bristol, Bristol, UK; Department of Rheumatology, University of Ottawa, Ottawa; Division of Rheumatology, Mount Sinai Hospital, Toronto; Division of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.3899/jrheum.171405DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726391PMC
August 2019

Serum biomarkers of glucocorticoid response and safety in anti-neutrophil cytoplasmic antibody-associated vasculitis and juvenile dermatomyositis.

Steroids 2018 12 21;140:159-166. Epub 2018 Oct 21.

ReveraGen BioPharma, 155 Gibbs St., Suite 433, Rockville, MD 20850, USA; School of Pharmacy and Pharmaceutical Sciences, Binghamton University - SUNY, 4400 Vestal Pkwy E, Binghamton, NY 13902, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0039128X183019
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http://dx.doi.org/10.1016/j.steroids.2018.10.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640634PMC
December 2018

Assessing Performance of Internal Medicine Residents.

Authors:
Paul A Monach

JAMA 2017 03;317(12):1276-1277

Rheumatology Section, Boston University School of Medicine, Boston, Massachusetts.

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http://dx.doi.org/10.1001/jama.2017.0890DOI Listing
March 2017

Case 6-2017. A 57-year-old woman with fatigue, sweats, weight loss, headache, and skin lesions.

N Engl J Med 2017 Feb;376(8):775-786

From the Department of Medicine, Boston University School of Medicine (P.A.M.), the Medical Service, Veterans Affairs Boston Healthcare System (P.A.M.), the Departments of Medicine (J.H.S.), Radiology (A.S.), and Pathology (R.M.N.), Massachusetts General Hospital, and the Departments of Medicine (J.H.S.), Radiology (A.S.), and Pathology (R.M.N.), Harvard Medical School - all in Boston.

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http://dx.doi.org/10.1056/NEJMcpc1613461DOI Listing
February 2017

Editorial: Defining and Refining the Risk of Venous Thromboembolism in Giant Cell Arteritis.

Authors:
Paul A Monach

Arthritis Rheumatol 2017 01;69(1):3-5

Boston University School of Medicine and VA Boston Healthcare System, Boston, Massachusetts.

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http://dx.doi.org/10.1002/art.39846DOI Listing
January 2017

The Birmingham Vasculitis Activity Score as a Measure of Disease Activity in Patients with Giant Cell Arteritis.

J Rheumatol 2016 06 1;43(6):1078-84. Epub 2016 Apr 1.

From the Division of Rheumatology, University of California, Los Angeles, Los Angeles, California; Department of Biostatistics, University of South Florida, Tampa, Florida, USA; Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario, Canada; Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio, USA; Division of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology, University of Pittsburgh, Pittsburgh, Pennsylvania; Division of Rheumatology and Clinical Immunology, University of Pennsylvania, Philadelphia, Pennsylvania; The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.T.A. Kermani, MD, MS, Division of Rheumatology, University of California, Los Angeles; D. Cuthbertson, MS, Department of Biostatistics, University of South Florida; S. Carette, MD, FRCPC, Division of Rheumatology, Mount Sinai Hospital; G.S. Hoffman, MD, MS, Center for Vasculitis Care and Research, Cleveland Clinic; N.A. Khalidi, MD, FRCPC, Division of Rheumatology, St. Joseph's Healthcare, McMaster University; C.L. Koening, MD, MS, Division of Rheumatology, University of Utah; C.A. Langford, MD, MHS, Center for Vasculitis Care and Research, Cleveland Clinic; K. McKinnon-Maksimowicz, DO, Division of Rheumatology, University of Pittsburgh; C.A. McAlear, MA, Division of Rheumatology and Clinical Immunology, University of Pennsylvania; P.A. Monach, MD, PhD, The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine; P. Seo, MD, MHS, Division of Rheumatology, Johns Hopkins University; K.J. Warrington, MD, Division of Rheumatology, Mayo Clinic

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http://dx.doi.org/10.3899/jrheum.151063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891218PMC
June 2016

Vasculitis in patients with inflammatory bowel diseases: A study of 32 patients and systematic review of the literature.

Semin Arthritis Rheum 2016 Feb 26;45(4):475-82. Epub 2015 Jul 26.

Division of Rheumatology, Mount Sinai Hospital, University of Toronto, The Joseph and Wolf Lebovic Building, 60 Murray St, Ste 2-220, Toronto, Ontario, Canada M5T 3L9. Electronic address:

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http://dx.doi.org/10.1016/j.semarthrit.2015.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4982464PMC
February 2016

Primary angiitis of the central nervous system in adults and children.

Rheum Dis Clin North Am 2015 ;41(1):47-62, viii

Section of Rheumatology, Department of Medicine, Boston University School of Medicine, 72 East Concord Street, E533, Boston, MA 02118, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0889857X140009
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http://dx.doi.org/10.1016/j.rdc.2014.09.004DOI Listing
July 2015

Disease Relapses among Patients with Giant Cell Arteritis: A Prospective, Longitudinal Cohort Study.

J Rheumatol 2015 Jul 15;42(7):1213-7. Epub 2015 Apr 15.

From the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota; Department of Biostatistics, University of South Florida, Tampa, Florida, USA; Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario, Canada; Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio, USA; Division of Rheumatology, St. Joseph's Healthcare, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, Pennsylvania; The Vasculitis Center, Section of Rheumatology, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; University of California at Los Angeles (UCLA), Los Angeles, California, USA.T.A. Kermani, MD, MS, UCLA; K.J. Warrington, MD, Division of Rheumatology, Mayo Clinic College of Medicine; D. Cuthbertson, MS, Department of Biostatistics, University of South Florida; S. Carette, MD, FRCPC, Division of Rheumatology, Mount Sinai Hospital; G.S. Hoffman, MD, MS, Center for Vasculitis Care and Research, Cleveland Clinic; N.A. Khalidi, MD, FRCPC, Division of Rheumatology, St. Joseph's Healthcare, McMaster University; C.L. Koening, MD, MS, Division of Rheumatology, University of Utah; C.A. Langford, MD, MHS, Center for Vasculitis Care and Research, Cleveland Clinic; K. Maksimowicz-McKinnon, DO, Division of Rheumatology and Clinical Immunology, University of Pittsburgh; C.A. McAlear, MA, The Vasculitis Center, Section of Rheumatology, Boston University School of Medicine, and Division of Rheumatology, University of Pennsylvania School of Medicine; P.A. Monach, MD, PhD, The Vasculitis Center, Section of Rheumatology, Boston University School of Medicine; P. Seo, MD, MHS, Division of Rheumatology, Johns Hopkins University

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http://www.jrheum.org/content/42/7/1213.full.pdf
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http://www.jrheum.org/cgi/doi/10.3899/jrheum.141347
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http://dx.doi.org/10.3899/jrheum.141347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505815PMC
July 2015

Cardiac Involvement in Granulomatosis with Polyangiitis.

J Rheumatol 2015 Jul 1;42(7):1209-12. Epub 2015 May 1.

From the Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario, Canada; Health Informatics Institute, University of South Florida, Tampa, Florida; Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio, USA; Division of Rheumatology, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology, University of Pennsylvania, Philadelphia; Division of Rheumatology, University of Pittsburgh, Pennsylvania; The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; Division of Pulmonary and Critical Care Medicine, and the Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota, USA.L. McGeoch, MD; S. Carette, MD, Division of Rheumatology, Mount Sinai Hospital; D. Cuthbertson, MS, Health Informatics Institute, University of South Florida; G.S. Hoffman, MD, Center for Vasculitis Care and Research, Cleveland Clinic; N. Khalidi, MD, Division of Rheumatology, McMaster University; C.L. Koening, MD, Division of Rheumatology, University of Utah; C.A. Langford, MD, Center for Vasculitis Care and Research, Cleveland Clinic; C.A. McAlear, MA, Division of Rheumatology, University of Pennsylvania; L. Moreland, MD, Division of Rheumatology, University of Pittsburgh; P.A. Monach, MD, PhD, The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine; P. Seo, MD, Division of Rheumatology, Johns Hopkins University; U. Specks, MD, Division of Pulmonary and Critical Care Medicine; S.R. Ytterberg, MD, Division of Rheumatology, Mayo Clinic College of Medicine; P.A. Merkel, MD, MPH, Division of Rheumatology, University of Pennsylvania; C. Pagnoux, MD, MSc, MPH, Division of Rheumatology, Mount Sinai Hospital.

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http://dx.doi.org/10.3899/jrheum.141513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505809PMC
July 2015

A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility.

Am J Hum Genet 2015 Apr 26;96(4):565-80. Epub 2015 Mar 26.

Instituto de Parasitología y Biomedicina "López-Neyra," CSIC, PTS Granada, Granada 18016, Spain.

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http://dx.doi.org/10.1016/j.ajhg.2015.02.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4385191PMC
April 2015

The tumor microenvironment shapes lineage, transcriptional, and functional diversity of infiltrating myeloid cells.

Cancer Immunol Res 2014 Jul 31;2(7):655-67. Epub 2014 Mar 31.

Authors' Affiliations: Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute; Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts; Departments of

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http://dx.doi.org/10.1158/2326-6066.CIR-13-0209DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4194071PMC
July 2014

Biomarkers in vasculitis.

Authors:
Paul A Monach

Curr Opin Rheumatol 2014 Jan;26(1):24-30

Boston University School of Medicine, Boston, MA, USA.

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http://dx.doi.org/10.1097/BOR.0000000000000009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015522PMC
January 2014

ANCA-associated vasculitis: a prothrombotic state even in remission?

Authors:
Paul A Monach

J Rheumatol 2013 Dec;40(12):1935-7

Section of Rheumatology, Vasculitis Center, Boston University School of Medicine, 72 East Concord Street, E-533, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.3899/jrheum.131069DOI Listing
December 2013

New features of disease after diagnosis in 6 forms of systemic vasculitis.

J Rheumatol 2013 Nov 1;40(11):1905-12. Epub 2013 Aug 1.

From The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts; Department of Biostatistics, University of South Florida, Tampa, Florida; Division of Rheumatology, Mount Sinai Hospital, Toronto, Ontario; and the Center for Vasculitis Care and Research, Cleveland Clinic, Cleveland, Ohio; Division of Rheumatology, McMaster University, Hamilton, Ontario, Canada; Division of Rheumatology, University of Utah, Salt Lake City, Utah; Division of Rheumatology, University of Pittsburgh; Division of Rheumatology, Johns Hopkins University, Baltimore, Maryland; Division of Pulmonary and Critical Care Medicine, Mayo Clinic College of Medicine, Rochester; Division of Rheumatology, Mayo Clinic College of Medicine, Rochester, Minnesota; and Division of Rheumatology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.3899/jrheum.121473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4292850PMC
November 2013

IgG4-related Disease: 2013 Update.

Authors:
Paul A Monach

Curr Treat Options Cardiovasc Med 2013 Apr;15(2):214-23

Vasculitis Center and Section of Rheumatology, Boston University School of Medicine, 72 East Concord Street, E-533, Boston, MA, 02118, USA,

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http://dx.doi.org/10.1007/s11936-013-0232-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662045PMC
April 2013

L25. Medical treatment of subglottic stenosis in granulomatosis with polyangiitis (Wegener's).

Authors:
Paul A Monach

Presse Med 2013 Apr 26;42(4 Pt 2):575-6. Epub 2013 Feb 26.

Boston University School of Medicine, Vasculitis Center, Section of Rheumatology, 72, East Concord Street, E-533, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/j.lpm.2013.01.025DOI Listing
April 2013

Repeating tests: different roles in research studies and clinical medicine.

Authors:
Paul A Monach

Biomark Med 2012 Oct;6(5):691-703

Department of Medicine, Section of Rheumatology, Boston University School of Medicine, 72 E Concord St, E-533, Boston, MA 02118, USA.

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http://dx.doi.org/10.2217/bmm.12.57DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651832PMC
October 2012

Distribution of arterial lesions in Takayasu's arteritis and giant cell arteritis.

Ann Rheum Dis 2012 Aug 10;71(8):1329-34. Epub 2012 Feb 10.

The Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1136/annrheumdis-2011-200795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3729734PMC
August 2012

Antineutrophil cytoplasmic antibodies, autoimmune neutropenia, and vasculitis.

Semin Arthritis Rheum 2011 Dec 19;41(3):424-33. Epub 2011 Apr 19.

Vasculitis Center, Section of Rheumatology, Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA.

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http://dx.doi.org/10.1016/j.semarthrit.2011.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3163109PMC
December 2011

Genetics of vasculitis.

Curr Opin Rheumatol 2010 Mar;22(2):157-63

Vasculitis Center, Section of Rheumatology, and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1097/BOR.0b013e32833654a8DOI Listing
March 2010

Incidence and prevention of bladder toxicity from cyclophosphamide in the treatment of rheumatic diseases: a data-driven review.

Arthritis Rheum 2010 Jan;62(1):9-21

Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1002/art.25061DOI Listing
January 2010

Thromboembolic disease in vasculitis.

Curr Opin Rheumatol 2009 Jan;21(1):41-6

The Vasculitis Center, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts 02118, USA.

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https://insights.ovid.com/crossref?an=00002281-200901000-000
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http://dx.doi.org/10.1097/BOR.0b013e32831de4e7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204384PMC
January 2009

The K/BxN arthritis model.

Curr Protoc Immunol 2008 May;Chapter 15:Unit 15.22

Joslin Diabetes Center, Harvard Medical School, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/0471142735.im1522s81DOI Listing
May 2008

Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1.

Proc Natl Acad Sci U S A 2007 Feb 2;104(7):2325-30. Epub 2007 Feb 2.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0610852103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1892913PMC
February 2007

Characterization of relapses in adult idiopathic inflammatory myopathies.

Clin Rheumatol 2006 Jul 3;25(4):476-81. Epub 2005 Nov 3.

Department of Internal Medicine, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

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http://link.springer.com/content/pdf/10.1007/s10067-005-0075
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http://link.springer.com/10.1007/s10067-005-0075-3
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http://dx.doi.org/10.1007/s10067-005-0075-3DOI Listing
July 2006

The role of antibodies in mouse models of rheumatoid arthritis, and relevance to human disease.

Adv Immunol 2004 ;82:217-48

Section of Immunology and Immunogenetics, Joslin Diabetes Center, and Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S006527760482005
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http://dx.doi.org/10.1016/S0065-2776(04)82005-4DOI Listing
June 2004

Tuberculous osteomyelitis presenting as shoulder pain.

J Rheumatol 2003 Apr;30(4):851-6

Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA.

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April 2003