Publications by authors named "Patrick Villarese"

20Publications

ALK-transformed mature T lymphocytes restore early thymus progenitor features.

Authors:
Annabelle Congras Coralie Hoareau-Aveilla Nina Caillet Marie Tosolini Patrick Villarese Agata Cieslak Laura Rodriguez Vahid Asnafi Elisabeth Macintyre Gerda Egger Pierre Brousset Laurence Lamant Fabienne Meggetto

J Clin Invest 2020 Dec;130(12):6395-6408

INSERM, UMR1037 CRCT, F-31000, Toulouse, France.

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December 2020

A transcriptomic continuum of differentiation arrest identifies myeloid interface acute leukemias with poor prognosis.

Authors:
Jonathan Bond Aleksandra Krzywon Ludovic Lhermitte Christophe Roumier Anne Roggy Mohamed Belhocine Alexander Abdulkader Kheirallah Patrick Villarese Guillaume Hypolite Francine Garnache-Ottou Sylvie Castaigne Nicolas Boissel Vahid Asnafi Claude Preudhomme Hervé Dombret Elisa Laurenti Elizabeth Macintyre

Leukemia 2020 Jul 13. Epub 2020 Jul 13.

Université de Paris, Institut Necker Enfants Malades (INEM), Institut national de la santé et de la recherche médicale (INSERM UMR1151), 75743, Paris, France.

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July 2020

Droplet Digital PCR Quantification of Mantle Cell Lymphoma Follow-up Samples From Four Prospective Trials of the European MCL Network.

Authors:
Daniela Drandi Marion Alcantara Ichrafe Benmaad Arian Söhlbrandt Ludovic Lhermitte GianMaria Zaccaria Martina Ferrante Elisa Genuardi Barbara Mantoan Patrick Villarese Morgane Cheminant Irene Della Starza Elena Ciabatti Riccardo Bomben Cristina Jimenez Mary Callanan Chrystelle Abdo Cornelia Eckert Vincent Ribrag Sergio Cortelazzo Martin Dreyling Olivier Hermine Marie-Hélène Delfau-Larue Christiane Pott Marco Ladetto Simone Ferrero Elizabeth Macintyre

Hemasphere 2020 Apr 3;4(2):e347. Epub 2020 Apr 3.

Biological Hematology, Université de Paris (Descartes), Assistance Publique - Hôpitaux de Paris and Institut Necker Enfants Malades (INEM), Paris, France.

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April 2020

Adult T-cell acute lymphoblastic leukemias with IL7R pathway mutations are slow-responders who do not benefit from allogeneic stem-cell transplantation.

Authors:
Rathana Kim Nicolas Boissel Aurore Touzart Thibaut Leguay Florian Thonier Xavier Thomas Emmanuel Raffoux Françoise Huguet Patrick Villarese Cécile Fourrage Loïc Passini Mathilde Hunault Stéphane Lepretre Patrice Chevallier Thorsten Braun Véronique Lhéritier Sylvain Chantepie Sébastien Maury Martine Escoffre Emmanuelle Tavernier Yves Chalandon Carlos Graux Elizabeth Macintyre Norbert Ifrah Vahid Asnafi Hervé Dombret Ludovic Lhermitte

Leukemia 2020 07 28;34(7):1730-1740. Epub 2020 Jan 28.

Université de Paris, Institut Necker-Enfants Malades, Institut National de Recherche Médicale U1151, Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants-Malades, Paris, France.

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July 2020

A New and Simple TRG Multiplex PCR Assay for Assessment of T-cell Clonality: A Comparative Study from the EuroClonality Consortium.

Authors:
Marine Armand Coralie Derrieux Kheira Beldjord Tamara Wabeke Dido Lenze Elke Boone Monika Bruggemann Paul A S Evans Paula Gameiro Michael Hummel Patrick Villarese Patricia J T A Groenen Anton W Langerak Elizabeth A Macintyre Frederic Davi

Hemasphere 2019 Jun 4;3(3):e255. Epub 2019 Jun 4.

Department of Hematology, APHP Pitié-Salpêtrière Hospital and Sorbonne Université, Paris, France.

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June 2019

Standardized next-generation sequencing of immunoglobulin and T-cell receptor gene recombinations for MRD marker identification in acute lymphoblastic leukaemia; a EuroClonality-NGS validation study.

Authors:
Monika Brüggemann Michaela Kotrová Henrik Knecht Jack Bartram Myriam Boudjogrha Vojtech Bystry Grazia Fazio Eva Froňková Mathieu Giraud Andrea Grioni Jeremy Hancock Dietrich Herrmann Cristina Jiménez Adam Krejci John Moppett Tomas Reigl Mikael Salson Blanca Scheijen Martin Schwarz Simona Songia Michael Svaton Jacques J M van Dongen Patrick Villarese Stephanie Wakeman Gary Wright Giovanni Cazzaniga Frédéric Davi Ramón García-Sanz David Gonzalez Patricia J T A Groenen Michael Hummel Elizabeth A Macintyre Kostas Stamatopoulos Christiane Pott Jan Trka Nikos Darzentas Anton W Langerak

Leukemia 2019 09 26;33(9):2241-2253. Epub 2019 Jun 26.

Department of Immunology, Laboratory Medical Immunology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands.

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September 2019

A Single-Tube, EuroClonality-Inspired, TRG Clonality Multiplex PCR Aids Management of Patients with Enteropathic Diseases, including from Formaldehyde-Fixed, Paraffin-Embedded Tissues.

Authors:
Coralie Derrieux Amélie Trinquand Julie Bruneau Virginie Verkarre Ludovic Lhermitte Marion Alcantara Patrick Villarese Bertrand Meresse David Sibon Olivier Hermine Nicole Brousse Thierry Molina Christophe Cellier Nadine Cerf-Bensussan Georgia Malamut Elizabeth Macintyre

J Mol Diagn 2019 01 28;21(1):111-122. Epub 2018 Sep 28.

Hematology Laboratory, Necker-Enfants Malades Hosptial and Paris Descartes, Sorbonne Paris Cité University, Paris, France; Hematology Laboratory, Hôpital Necker-Enfants Malades, Assistance Publique des Hôpitaux de Paris, Paris, France; INSERM UMR1151 and Institut Necker-Enfants Malades, Paris, France; Centre national Expert des Lymphomes Associés à la maladie Coeliaque, Hôpital Necker-Enfants Malades, Assistance Publique des Hôpitaux de Paris, Paris, France. Electronic address:

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January 2019

Interleukin-15-Dependent T-Cell-like Innate Intraepithelial Lymphocytes Develop in the Intestine and Transform into Lymphomas in Celiac Disease.

Authors:
Julien Ettersperger Nicolas Montcuquet Georgia Malamut Nicolas Guegan Silvia Lopez-Lastra Ségolène Gayraud Christian Reimann Elodie Vidal Nicolas Cagnard Patrick Villarese Isabelle Andre-Schmutz Rita Gomes Domingues Cristina Godinho-Silva Henrique Veiga-Fernandes Ludovic Lhermitte Vahid Asnafi Elizabeth Macintyre Christophe Cellier Kheira Beldjord James P Di Santo Nadine Cerf-Bensussan Bertrand Meresse

Immunity 2016 09 6;45(3):610-625. Epub 2016 Sep 6.

INSERM UMR1163, Laboratory of Intestinal Immunity, Institut Imagine, 75015 Paris, France; Université Paris Descartes-Sorbonne Paris Cité and Institut Imagine, 75015 Paris, France. Electronic address:

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September 2016

Anaplastic large cell lymphoma arises in thymocytes and requires transient TCR expression for thymic egress.

Authors:
Tim I M Malcolm Patrick Villarese Camilla J Fairbairn Laurence Lamant Amélie Trinquand C Elizabeth Hook G A Amos Burke Laurence Brugières Katherine Hughes Dominique Payet Olaf Merkel Ana-Iris Schiefer Ibraheem Ashankyty Shahid Mian Mariusz Wasik Martin Turner Lukas Kenner Vahid Asnafi Elizabeth Macintyre Suzanne D Turner

Nat Commun 2016 Jan 12;7:10087. Epub 2016 Jan 12.

Department of Pathology, University of Cambridge, Cambridge CB21QP, UK.

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January 2016

Targeting IRAK1 in T-cell acute lymphoblastic leukemia.

Authors:
Charles Dussiau Amélie Trinquand Ludovic Lhermitte Mehdi Latiri Mathieu Simonin Agata Cieslak Nawel Bedjaoui Patrick Villarèse Els Verhoeyen Hervé Dombret Norbert Ifrah Elizabeth Macintyre Vahid Asnafi

Oncotarget 2015 Aug;6(22):18956-65

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut National de Recherche Médicale (INSERM) U1151 and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker-Enfants Malades, Paris, France.

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August 2015

A novel method for room temperature distribution and conservation of RNA and DNA reference materials for guaranteeing performance of molecular diagnostics in onco-hematology: A GBMHM study.

Authors:
Jean-Michel Cayuela Carole Mauté Anne-Lise Fabre Olivier Nibourel Stéphanie Dulucq Eric Delabesse Patrick Villarèse Sandrine Hayette Marie-Joelle Mozziconacci Elizabeth Macintyre

Clin Biochem 2015 Oct 12;48(15):982-7. Epub 2015 Apr 12.

Laboratory of Hematology, University Hospital Necker-Enfants-Malades, AP-HP, Paris, France.

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October 2015

RUNX1-dependent RAG1 deposition instigates human TCR-δ locus rearrangement.

Authors:
Agata Cieslak Sandrine Le Noir Amélie Trinquand Ludovic Lhermitte Don-Marc Franchini Patrick Villarese Stéphanie Gon Jonathan Bond Mathieu Simonin Laurent Vanhille Laurent Vanhile Christian Reimann Els Verhoeyen Jerome Larghero Emmanuelle Six Salvatore Spicuglia Isabelle André-Schmutz Anton Langerak Bertrand Nadel Elizabeth Macintyre Dominique Payet-Bornet Vahid Asnafi

J Exp Med 2014 Aug 18;211(9):1821-32. Epub 2014 Aug 18.

Université Paris Descartes Sorbonne Cité, Institut Necker-Enfants Malades (INEM), Institut national de recherche médicale (INSERM) U1151, and Laboratory of Onco-Hematology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Necker Enfants-Malades, 75015 Paris, France

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August 2014

The prognosis of CALM-AF10-positive adult T-cell acute lymphoblastic leukemias depends on the stage of maturation arrest.

Authors:
Raouf Ben Abdelali Vahid Asnafi Arnaud Petit Jean-Baptiste Micol Céline Callens Patrick Villarese Eric Delabesse Oumedaly Reman Stephane Lepretre Jean-Yves Cahn Gaelle Guillerm Céline Berthon Claude Gardin Bernadette Corront Thibaut Leguay Marie-Christine Béné Norbert Ifrah Guy Leverger Hervé Dombret Elizabeth Macintyre

Haematologica 2013 Nov 5;98(11):1711-7. Epub 2013 Jul 5.

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November 2013

Extensive molecular mapping of TCRα/δ- and TCRβ-involved chromosomal translocations reveals distinct mechanisms of oncogene activation in T-ALL.

Authors:
Sandrine Le Noir Raouf Ben Abdelali Marc Lelorch Julie Bergeron Stephanie Sungalee Dominique Payet-Bornet Patrick Villarèse Arnaud Petit Céline Callens Ludovic Lhermitte Laurence Baranger Isabelle Radford-Weiss Marie-José Grégoire Hervé Dombret Norbert Ifrah Salvatore Spicuglia Serge Romana Jean Soulier Bertrand Nadel Elizabeth Macintyre Vahid Asnafi

Blood 2012 Oct 4;120(16):3298-309. Epub 2012 Sep 4.

Université Paris Descartes, Centre National de la Recherche Scientifique UMR, France.

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October 2012

Clinical impact of NOTCH1 and/or FBXW7 mutations, FLASH deletion, and TCR status in pediatric T-cell lymphoblastic lymphoma.

Authors:
Celine Callens Frederic Baleydier Etienne Lengline Raouf Ben Abdelali Arnaud Petit Patrick Villarese Agata Cieslak Veronique Minard-Colin Anne Rullier Anne Moreau André Baruchel Claudine Schmitt Vahid Asnafi Yves Bertrand Elizabeth Macintyre

J Clin Oncol 2012 Jun 30;30(16):1966-73. Epub 2012 Apr 30.

Université Paris Descartes Sorbonne Paris Cite, France.

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June 2012

TLX homeodomain oncogenes mediate T cell maturation arrest in T-ALL via interaction with ETS1 and suppression of TCRα gene expression.

Authors:
Saïda Dadi Sandrine Le Noir Dominique Payet-Bornet Ludovic Lhermitte Joaquin Zacarias-Cabeza Julie Bergeron Patrick Villarèse Elodie Vachez Willem A Dik Corinne Millien Isabelle Radford Els Verhoeyen François-Loïc Cosset Arnaud Petit Norbert Ifrah Hervé Dombret Olivier Hermine Salvatore Spicuglia Anton W Langerak Elizabeth A Macintyre Bertrand Nadel Pierre Ferrier Vahid Asnafi

Cancer Cell 2012 Apr;21(4):563-76

Department of Hematologye, Université de Médecine Paris Descartes Sorbonne Cité, Centre National de la Recherche Scientifique (CNRS), France.

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April 2012

Cartridge-based automated BCR-ABL1 mRNA quantification: solving the issues of standardization, at what cost?

Authors:
Jean-Michel Cayuela Elizabeth Macintyre Meryl Darlington Raouf Ben Abdelali Xavier Fund Patrick Villarese Michel Tulliez Emmanuel Raffoux François Sigaux Delphine Réa Valerie Seror

Haematologica 2011 May 17;96(5):664-71. Epub 2011 Feb 17.

Laboratoire Central d'Hématologie, Hôpital Saint-Louis, 1 av. Claude Vellefaux, 75475 Paris cedex 10, France.

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May 2011

Acute monocytic leukemia with coexpression of minor BCR-ABL1 and PICALM-MLLT10 fusion genes along with overexpression of HOXA9.

Authors:
Audrey Sindt Benedicte Deau Wajih Brahim Anne Staal Sorin Visanica Patrick Villarese Jean-Philippe Rault Elizabeth Macintyre Eric Delabesse

Genes Chromosomes Cancer 2006 Jun;45(6):575-82

Department of Biochemistry and Genetics, CHU Brabois, Nancy, France.

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June 2006

Age-related phenotypic and oncogenic differences in T-cell acute lymphoblastic leukemias may reflect thymic atrophy.

Authors:
Vahid Asnafi Kheira Beldjord Marta Libura Patrick Villarese Corrine Millien Paola Ballerini Emilienne Kuhlein Marina Lafage-Pochitaloff Eric Delabesse Olivier Bernard Elizabeth Macintyre

Blood 2004 Dec 30;104(13):4173-80. Epub 2004 Mar 30.

Necker-Enfants-Malades and Trousseau, Assistance Publique-Hopitaux de Paris, INSERM EMIU210 and Université Paris V, Hôpital Purpan, Toulouse, France.

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December 2004

FLT3 and MLL intragenic abnormalities in AML reflect a common category of genotoxic stress.

Authors:
Marta Libura Vahid Asnafi Angela Tu Eric Delabesse Isabelle Tigaud Florence Cymbalista Annelise Bennaceur-Griscelli Patrick Villarese Gabriel Solbu Anne Hagemeijer Kheira Beldjord Olivier Hermine Elizabeth Macintyre

Blood 2003 Sep 5;102(6):2198-204. Epub 2003 Jun 5.

Laboratoire d'Hématologie, Tour Pasteur, Hôpital Necker, 149-161 rue de Sèvres, 75743 Paris cedex 15, France.

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September 2003