Patrick Schultz

Atomic structure of the SAGA complex and it's interaction with TBP.

Authors:

Gabor Papai Alexandre Frechard Olga Kolesnikova Corinne Crucifix Patrick Schultz Adam Ben-Shem

C R Biol 2021 Feb 4;343(3):247-255. Epub 2021 Feb 4.

Centre National de la Recherche Scientifique, UMR7104, Illkirch, France.

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February 2021

The NANOTUMOR consortium - Towards the Tumor Cell Atlas.

Authors:

Florent Colin Kristine Schauer Ali Hamiche Pierre Martineau Jean-Paul Borg Jan Bednar Giulia Bertolin Luc Camoin Yves Collette Stephan Dimitrov Isabelle Fournier Vincent Hyenne Marco A Mendoza-Parra Xavier Morelli Philippe Rondé Izabela Sumara Marc Tramier Patrick Schultz Jacky G Goetz

Biol Cell 2021 Feb 7. Epub 2021 Feb 7.

INSERM UMR_S1109, Tumor Biomechanics Lab, Université de Strasbourg, Fédération de Médecine Translationnelle de Strasbourg (FMTS), CNRS SNC5055, Strasbourg, France.

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February 2021

Optimization of Sample Preparation for the Observation of Macromolecular Complexes by Electron (cryo-)Microscopy.

Authors:

Alexandre Frechard Grigory Sharov Maximilien Werderer Patrick Schultz

Methods Mol Biol 2021 ;2247:243-256

Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Integrated Structural Biology, Equipe labellisée Ligue Contre le Cancer, Centre National de la Recherche Scientifique (CNRS), UMR 7104, Institut National de la Santé et de la Recherche Médicale (INSERM), U1258, Université de Strasbourg, Illkirch, France.

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January 2021

Architecture of the multi-functional SAGA complex and the molecular mechanism of holding TBP.

Authors:

Adam Ben-Shem Gabor Papai Patrick Schultz

FEBS J 2020 Sep 18. Epub 2020 Sep 18.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

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September 2020

Cryo-FIB-SEM as a promising tool for localizing proteins in 3D.

Authors:

Daniele Spehner Anna M Steyer Luca Bertinetti Igor Orlov Lucas Benoit Karin Pernet-Gallay Andreas Schertel Patrick Schultz

J Struct Biol 2020 07 6;211(1):107528. Epub 2020 May 6.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Department of Integrated Structural Biology, Equipe labellisée Ligue Contre le Cancer, Illkirch, France; Centre National de la Recherche Scientifique, UMR7104, Illkirch, France; Institut National de la Santé et de la Recherche Médicale, U1258 Illkirch, France; Université de Strasbourg, Illkirch, France.

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July 2020

Structure of SAGA and mechanism of TBP deposition on gene promoters.

Authors:

Gabor Papai Alexandre Frechard Olga Kolesnikova Corinne Crucifix Patrick Schultz Adam Ben-Shem

Nature 2020 01 22;577(7792):711-716. Epub 2020 Jan 22.

Institut de Génétique et de Biologie Moléculaire et Cellulaire, Integrated Structural Biology Department, Equipe labellisée Ligue Contre le Cancer, Illkirch, France.

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January 2020

Over the rainbow: A practical guide for fluorescent protein selection in plant FRET experiments.

Authors:

Grégoire Denay Patrick Schultz Sebastian Hänsch Stefanie Weidtkamp-Peters Rüdiger Simon

Plant Direct 2019 Dec 6;3(12):e00189. Epub 2019 Dec 6.

Institute for Developmental Genetics Heinrich Heine University Düsseldorf Düsseldorf Germany.

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December 2019

A Cellular Insulator against CLE45 Peptide Signaling.

Authors:

Alice S Breda Ora Hazak Patrick Schultz Pauline Anne Moritz Graeff Rüdiger Simon Christian S Hardtke

Curr Biol 2019 08 18;29(15):2501-2508.e3. Epub 2019 Jul 18.

Department of Plant Molecular Biology, University of Lausanne, Biophore Building, 1015 Lausanne, Switzerland. Electronic address:

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August 2019

Molecular structure of promoter-bound yeast TFIID.

Authors:

Olga Kolesnikova Adam Ben-Shem Jie Luo Jeff Ranish Patrick Schultz Gabor Papai

Nat Commun 2018 11 7;9(1):4666. Epub 2018 Nov 7.

Department of Integrated Structural Biology, Equipe labellisée Ligue Contre le Cancer, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, 67404, France.

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November 2018

Structural Basis for NusA Stabilized Transcriptional Pausing.

Authors:

Xieyang Guo Alexander G Myasnikov James Chen Corinne Crucifix Gabor Papai Maria Takacs Patrick Schultz Albert Weixlbaumer

Mol Cell 2018 03;69(5):816-827.e4

Department of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), 67404 Illkirch Cedex, France; Université de Strasbourg, 67404 Illkirch Cedex, France; Centre National de la Recherche Scientifique (CNRS), UMR 7104, 67404 Illkirch Cedex, France; Institut National de la Santé et de la Recherche Médicale (Inserm), U964, 67404 Illkirch Cedex, France. Electronic address:

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March 2018

Molecular architecture of potassium chloride co-transporter KCC2.

Authors:

Morgane Agez Patrick Schultz Igor Medina David J Baker Matthew P Burnham Ross A Cardarelli Leslie C Conway Kelly Garnier Stefan Geschwindner Anders Gunnarsson Eileen J McCall Alexandre Frechard Stéphane Audebert Tarek Z Deeb Stephen J Moss Nicholas J Brandon Qi Wang Niek Dekker Anass Jawhari

Sci Rep 2017 11 28;7(1):16452. Epub 2017 Nov 28.

CALIXAR, 60 avenue Rockefeller, 69008, Lyon, France.

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November 2017

Structure of the transcription activator target Tra1 within the chromatin modifying complex SAGA.

Authors:

Grigory Sharov Karine Voltz Alexandre Durand Olga Kolesnikova Gabor Papai Alexander G Myasnikov Annick Dejaegere Adam Ben Shem Patrick Schultz

Nat Commun 2017 11 16;8(1):1556. Epub 2017 Nov 16.

Department of Integrated Structural Biology, Institut de Génétique et de Biologie Moléculaire et Cellulaire, 67404, Illkirch, France.

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November 2017

Microtome-integrated microscope system for high sensitivity tracking of in-resin fluorescence in blocks and ultrathin sections for correlative microscopy.

Authors:

Nicolas Lemercier Volker Middel Didier Hentsch Serge Taubert Masanari Takamiya Tanja Beil Jean-Luc Vonesch Tilo Baumbach Patrick Schultz Claude Antony Uwe Strähle

Sci Rep 2017 10 19;7(1):13583. Epub 2017 Oct 19.

Institute of Toxicology and Genetics, Karlsruhe Institute of Technology, Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.

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October 2017

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.

Mol Cell 2017 06;66(5):729

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June 2017

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.

Mol Cell 2017 May;66(3):384-397.e8

Institut for Advanced Biosciences, Inserm U 1209, CNRS UMR 5309, Université Grenoble Alpes, 38000 Grenoble, France. Electronic address:

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May 2017

A central cavity within the holo-translocon suggests a mechanism for membrane protein insertion.

Authors:

Mathieu Botte Nathan R Zaccai Jelger Lycklama À Nijeholt Remy Martin Kèvin Knoops Gabor Papai Juan Zou Aurélien Deniaud Manikandan Karuppasamy Qiyang Jiang Abhishek Singha Roy Klaus Schulten Patrick Schultz Juri Rappsilber Giuseppe Zaccai Imre Berger Ian Collinson Christiane Schaffitzel

Sci Rep 2016 12 7;6:38399. Epub 2016 Dec 7.

European Molecular Biology Laboratory, Grenoble Outstation, 71 Avenue des Martyrs, 38042 Grenoble, France.

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December 2016

Automatic segmentation of high pressure frozen and freeze-substituted mouse retina nuclei from FIB-SEM tomograms.

Authors:

Thai V Hoang Caroline Kizilyaprak Danièle Spehner Bruno M Humbel Patrick Schultz

J Struct Biol 2017 02 8;197(2):123-134. Epub 2016 Oct 8.

IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire), 1, rue Laurent Fries, BP 10142, 67404 Illkirch, France; Inserm, U964, Illkirch, France; CNRS, UMR7104, Illkirch, France; Université de Strasbourg, Strasbourg, France. Electronic address:

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February 2017

Covalent Tethering and Residues with Bulky Hydrophobic Side Chains Enable Self-Assembly of Distinct Amyloid Structures.

Authors:

Jérémy Ruiz Régis Boehringer Marcel Grogg Jésus Raya Alicia Schirer Corinne Crucifix Petra Hellwig Patrick Schultz Vladimir Torbeev

Chembiochem 2016 12 9;17(23):2274-2285. Epub 2016 Nov 9.

ISIS (Institut de Science et d'Ingénierie Supramoléculaires) and, icFRC (International Center for Frontier Research in Chemistry), University of Strasbourg, CNRS-, UMR 7006, 8 allée Gaspard Monge, 67083, Strasbourg, France.

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December 2016

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity.

Mol Cell 2016 08 4;63(4):674-685. Epub 2016 Aug 4.

Université de Grenoble Alpes/INSERM U1209/CNRS UMR 5309, 38042 Grenoble Cedex 9, France. Electronic address:

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August 2016

Structure of the initiation-competent RNA polymerase I and its implication for transcription.

Authors:

Michael Pilsl Corinne Crucifix Gabor Papai Ferdinand Krupp Robert Steinbauer Joachim Griesenbeck Philipp Milkereit Herbert Tschochner Patrick Schultz

Nat Commun 2016 07 15;7:12126. Epub 2016 Jul 15.

Department of Integrated Structural Biology, IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire) INSERM, U964; CNRS/Strasbourg University, UMR7104 1, rue Laurent Fries, BP10142, 67404 Illkirch, France.

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July 2016

Protein Delivery System Containing a Nickel-Immobilized Polymer for Multimerization of Affinity-Purified His-Tagged Proteins Enhances Cytosolic Transfer.

Authors:

Viktoriia Postupalenko Dominique Desplancq Igor Orlov Youri Arntz Danièle Spehner Yves Mely Bruno P Klaholz Patrick Schultz Etienne Weiss Guy Zuber

Angew Chem Int Ed Engl 2015 Sep 31;54(36):10583-6. Epub 2015 Jul 31.

UMR 7199 and UMR 7213 CNRS Université de Strasbourg, Faculté de Pharmacie, Illkirch (France).

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September 2015

Chemical cross-linking and mass spectrometry to determine the subunit interaction network in a recombinant human SAGA HAT subcomplex.

Authors:

Nha-Thi Nguyen-Huynh Grigory Sharov Clément Potel Pélagie Fichter Simon Trowitzsch Imre Berger Valérie Lamour Patrick Schultz Noëlle Potier Emmanuelle Leize-Wagner

Protein Sci 2015 Aug 14;24(8):1232-46. Epub 2015 Apr 14.

Laboratoire de Spectrométrie de Masse des Interactions et des Systèmes (LSMIS) UMR 7140 CNRS/Université de Strasbourg - "Chimie de la Matière Complexe", 1 Rue Blaise Pascal, 67008, Strasbourg, France.

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August 2015

Live cell immunogold labelling of RNA polymerase II.

Authors:

Igor Orlov Andreas Schertel Guy Zuber Bruno Klaholz Robert Drillien Etienne Weiss Patrick Schultz Danièle Spehner

Sci Rep 2015 Feb 9;5:8324. Epub 2015 Feb 9.

Department of Integrated Structural Biology, IGBMC (Institut de Génétique et de Biologie Moléculaire et Cellulaire) INSERM, U964; CNRS/Strasbourg University, UMR7104 1, rue Laurent Fries, BP10142 67404 Illkirch, France.

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February 2015

Cytoplasmic TAF2-TAF8-TAF10 complex provides evidence for nuclear holo-TFIID assembly from preformed submodules.

Authors:

Simon Trowitzsch Cristina Viola Elisabeth Scheer Sascha Conic Virginie Chavant Marjorie Fournier Gabor Papai Ima-Obong Ebong Christiane Schaffitzel Juan Zou Matthias Haffke Juri Rappsilber Carol V Robinson Patrick Schultz Laszlo Tora Imre Berger

Nat Commun 2015 Jan 14;6:6011. Epub 2015 Jan 14.

1] European Molecular Biology Laboratory, Grenoble Outstation, 6 rue Jules Horowitz, 38042 Grenoble, France [2] Unit for Virus Host-Cell Interactions, University Grenoble Alpes-EMBL-CNRS, 6 rue Jules Horowitz, 38042 Grenoble, France [3] School of Biochemistry, Bristol University, Bristol BS8 1TD, UK.

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January 2015

[Structural insight into negative DNA supercoiling by DNA gyrase, a bacterial type 2A DNA topoisomerase].

Authors:

Julie Papillon Jean-François Ménétret Claire Batisse Reynald Hélye Patrick Schultz Noëlle Potier Valérie Lamour

Med Sci (Paris) 2014 Dec 24;30(12):1081-4. Epub 2014 Dec 24.

IGBMC, départment de biologie structurale intégrative, CNRS UMR7104, Inserm U964, université de Strasbourg, 1, rue Laurent Fries, 67400 Illkirch, France - hôpitaux universitaires de Strasbourg, fédération de médecine translationnelle de Strasbourg, 67000 Strasbourg, France.

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December 2014