Patrick Netter

Patrick Netter

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Patrick Netter

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Constitutive activation of EGFR is associated with tumor progression and plays a prominent role in malignant phenotype of chondrosarcoma.

Oncotarget 2019 May 7;10(34):3166-3182. Epub 2019 May 7.

UMR7365 Centre National de la Recherche Scientifique (CNRS), Université de Lorraine, Biopôle, Faculty of Medicine, Nancy 54505, France.

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http://www.oncotarget.com/fulltext/26899
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http://dx.doi.org/10.18632/oncotarget.26899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6516718PMC
May 2019

Non-canonical Wnt induces chondrocyte de-differentiation through Frizzled 6 and DVL-2/B-raf/CaMKIIα/syndecan 4 axis.

Cell Death Differ 2018 08 19;25(8):1442-1456. Epub 2018 Jan 19.

UMR7365 CNRS-University of Lorraine, Biopôle, Faculty of Medicine, 54505, Vandoeuvre-lès-Nancy, France.

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http://www.nature.com/articles/s41418-017-0050-y
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http://dx.doi.org/10.1038/s41418-017-0050-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6113213PMC
August 2018

Zinc-Alpha-2-Glycoprotein in Inflammatory Bowel Disease.

Inflamm Bowel Dis 2018 04;24(5):e10

IMoPA, UMR7365 CNRS-Université de Lorraine, Vandœuvre Les Nancy, France.

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http://dx.doi.org/10.1093/ibd/izy120DOI Listing
April 2018

Management of patients with inflammatory bowel disease and spondyloarthritis.

Expert Rev Clin Pharmacol 2017 Dec 20;10(12):1363-1374. Epub 2017 Sep 20.

g Inserm U954 and Department of Gastroenterology , Nancy University Hospital, Université de Lorraine , Vandœuvre-lès-Nancy , France.

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http://dx.doi.org/10.1080/17512433.2017.1377609DOI Listing
December 2017

Association between rheumatoid arthritis and systemic mastocytosis: a case report and literature review.

Clin Rheumatol 2016 Oct 9;35(10):2619-23. Epub 2016 Aug 9.

UMR 7365 IMoPA CNRS-Université de Lorraine, Biopôle de l'Université de Lorraine, Campus biologie-santé, 54505, Vandœuvre-lès-Nancy cedex, France.

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http://link.springer.com/10.1007/s10067-016-3368-9
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http://dx.doi.org/10.1007/s10067-016-3368-9DOI Listing
October 2016

PLGA-Based Nanoparticles: a Safe and Suitable Delivery Platform for Osteoarticular Pathologies.

Pharm Res 2015 Dec 2;32(12):3886-98. Epub 2015 Jul 2.

Ingénierie Moléculaire et Physiopathologie Articulaire, Unité Mixte de Recherche 7365, Centre National de la Recherche Scientifique - Université de Lorraine, Biopôle de l'Université de Lorraine, Campus Biologie Santé, 9 Avenue de la Forêt de Haye CS 50184, 54505, Vandœuvre Lès Nancy cedex, France.

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http://dx.doi.org/10.1007/s11095-015-1748-5DOI Listing
December 2015

Chondrocalcin is internalized by chondrocytes and triggers cartilage destruction via an interleukin-1β-dependent pathway.

Matrix Biol 2013 Oct-Nov;32(7-8):443-51. Epub 2013 Jul 10.

Molecular, Cellular, Therapeutic Engineering & Glycosyl Transferases (MolCelTeG), UMR 7365 CNRS-Université de Lorraine, Biopôle du Campus Biologie-Santé, Faculté de Médecine, 9, Avenue de la Forêt de Haye, BP 184, 54505 Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.1016/j.matbio.2013.06.002DOI Listing
July 2014

The cucurbitacins E, D and I: investigation of their cytotoxicity toward human chondrosarcoma SW 1353 cell line and their biotransformation in man liver.

Toxicol Lett 2013 Feb 27;216(2-3):189-99. Epub 2012 Nov 27.

UMR 7561 CNRS-Université Lorraine, School of Medicine, 9 Avenue de la forêt de Haye, BP 184, F-54505 Vandœuvre-lès-Nancy, Cedex, France.

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https://linkinghub.elsevier.com/retrieve/pii/S03784274120138
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http://dx.doi.org/10.1016/j.toxlet.2012.11.014DOI Listing
February 2013

Matrilin-3 switches from anti- to pro-anabolic upon integration to the extracellular matrix.

Matrix Biol 2012 Jun 10;31(5):290-8. Epub 2012 Apr 10.

UMR 7561 CNRS-Université de Lorraine, Faculté de Médecine, 9, Avenue de la Forêt de Haye, BP 184, 54505 Vandoeuvre-lès-Nancy, France.

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https://linkinghub.elsevier.com/retrieve/pii/S0945053X120006
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http://dx.doi.org/10.1016/j.matbio.2012.03.004DOI Listing
June 2012

Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators?

Arthritis Res Ther 2012 Mar 13;14(2):R60. Epub 2012 Mar 13.

Physiopathologie, Pharmacologie et Ingénierie Articulaire - PPIA-UMR 7561 CNRS UHP, Université de Lorraine, Faculté de Médecine, BP 184, 54505 Vandoeuvre Les Nancy, France.

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http://arthritis-research.biomedcentral.com/articles/10.1186
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http://dx.doi.org/10.1186/ar3774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446427PMC
March 2012

Identification of the human UDP-glucuronosyltransferase isoforms involved in the glucuronidation of the phytochemical ferulic acid.

Drug Metab Pharmacokinet 2011 14;26(4):341-50. Epub 2011 Mar 14.

Pharmacology Department of Basic Medical College, Wuhan University, China.

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February 2012

Alternative for anti-TNF antibodies for arthritis treatment.

Mol Ther 2011 Oct 2;19(10):1887-95. Epub 2011 Aug 2.

UMR 7561 CNRS, Nancy Université Physiopathologie, Pharmacologie et Ingénierie Articulaires, Vandoeuvre lès Nancy, France.

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http://dx.doi.org/10.1038/mt.2011.156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188747PMC
October 2011

Activation of PPARs α, β/δ, and γ Impairs TGF-β1-Induced Collagens' Production and Modulates the TIMP-1/MMPs Balance in Three-Dimensional Cultured Chondrocytes.

PPAR Res 2010 4;2010:635912. Epub 2010 Oct 4.

Laboratoire de Physiologie et Pharmacologie Articulaires (LPPA), UMR 7561 CNRS-UHP Nancy 1, avenue de la Forêt de Haye, BP 184, 54505 Vandœuvre-lès-Nancy Cedex, France.

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http://dx.doi.org/10.1155/2010/635912DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2957135PMC
July 2011

Calcium input potentiates the transforming growth factor (TGF)-beta1-dependent signaling to promote the export of inorganic pyrophosphate by articular chondrocyte.

J Biol Chem 2011 Jun 6;286(22):19215-28. Epub 2011 Apr 6.

Laboratoire de Physiopathologie, Pharmacologie et Ingénierie Articulaires, Faculté de Médecine, UMR 7561 CNRS-Nancy-Université, Vandœuvre-Lès-Nancy, France.

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http://dx.doi.org/10.1074/jbc.M110.175448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3103300PMC
June 2011

Metabolism of parabens (4-hydroxybenzoic acid esters) by hepatic esterases and UDP-glucuronosyltransferases in man.

Drug Metab Pharmacokinet 2010 1;25(6):568-77. Epub 2010 Oct 1.

UMR 7561 CNRS-Université Henri Poincaré Nancy-1, School of Medicine, Vandoeuvre-leà s-Nancy, France.

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May 2011

Expression of chondrogenic genes by undifferentiated vs. differentiated human mesenchymal stem cells using array technology.

Biomed Mater Eng 2010 ;20(3):175-81

UMR 7561 CNRS - UHP Nancy 1, Physiopathologie, Pharmacologie et Ingénierie Articulaires, Université Nancy, Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.3233/BME-2010-0629DOI Listing
February 2011

Evaluation of a rat knee mono-arthritis using microPET.

Biomed Mater Eng 2010 ;20(3):195-202

Service de Pharmacologie, Nancy Université, Physiopathologie, Pharmacologie et Ingénierie Articulaires, Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.3233/BME-2010-0632DOI Listing
February 2011

Inorganic phosphate (Pi) modulates the expression of key regulatory proteins of the inorganic pyrophosphate (PPi) metabolism in TGF-β1-stimulated chondrocytes.

Biomed Mater Eng 2010 ;20(3):209-15

Laboratoire de Physiopathologie, Pharmacologie et Ingénierie Articulaires, CNRS-Nancy University, Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.3233/BME-2010-0634DOI Listing
February 2011

Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of β1,3-glucuronosyltransferase I in pulmonary fibrosis.

Am J Physiol Lung Cell Mol Physiol 2011 Feb 5;300(2):L191-203. Epub 2010 Nov 5.

McGill Univ., Montréal, QC, Canada.

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http://dx.doi.org/10.1152/ajplung.00214.2010DOI Listing
February 2011

Biochemical and thermodynamic characterization of mutated β1,4-galactosyltransferase 7 involved in the progeroid form of the Ehlers-Danlos syndrome.

Biochem J 2010 Dec;432(2):303-11

ARN-RNP-structure fonction-maturation, Enzymologie Moléculaire et Structurale, Unité Mixte de Recherche 7214, CNRS-Nancy Université, Faculté des Sciences et Techniques, BP 239 Vandoeuvre-Les-Nancy, France.

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http://biochemj.org/lookup/doi/10.1042/BJ20100921
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http://dx.doi.org/10.1042/BJ20100921DOI Listing
December 2010

In vivo high-resolution MRI (7T) of femoro-tibial cartilage changes in the rat anterior cruciate ligament transection model of osteoarthritis: a cross-sectional study.

Rheumatology (Oxford) 2010 Sep 20;49(9):1654-64. Epub 2010 May 20.

UMR 7561 CNRS - Nancy University, Physiopathologie, Pharmacologie et Ingénierie Articulaires, Faculté de Médecine de Nancy, BP 184, Avenue de la Foret de Haye, F54505 Vandoeuvre, France.

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https://academic.oup.com/rheumatology/article-lookup/doi/10.
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http://dx.doi.org/10.1093/rheumatology/keq154DOI Listing
September 2010

Collagenous extracellular matrix of cartilage submitted to mechanical forces studied by second harmonic generation microscopy.

Photochem Photobiol 2010 Mar-Apr;86(2):302-10. Epub 2009 Nov 18.

Physiopathologie et Pharmacologie Articulaires UMR 7561 CNRS et Ingénierie Moléculaire et Thérapeutique FR CNRS-INSERM 3209, Faculté de Médecine, Nancy-Université, Vandoeuvre-lès-Nancy, France.

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http://doi.wiley.com/10.1111/j.1751-1097.2009.00648.x
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http://dx.doi.org/10.1111/j.1751-1097.2009.00648.xDOI Listing
August 2010

The inorganic pyrophosphate transporter ANK preserves the differentiated phenotype of articular chondrocyte.

J Biol Chem 2010 Apr 3;285(14):10572-82. Epub 2010 Feb 3.

Laboratoire de Physiopathologie, Pharmacologie et Ingénierie Articulaires, UMR 7561 CNRS-Nancy-Université, Avenue de la Forêt de Haye, BP184, 54505 Vandoeuvre-Lès-Nancy, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M109.050534
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http://dx.doi.org/10.1074/jbc.M109.050534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2856265PMC
April 2010

[Agrecan and articular cartilage: assessment of glycosyltransferases for the restoration of cartilage matrix in osteoarthritis].

J Soc Biol 2008 19;202(4):281-8. Epub 2008 Dec 19.

UMR CNRS-Université Henri Poincaré-Nancy "Physiopathologie et Pharmacologie Articulaires", France.

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http://dx.doi.org/10.1051/jbio:2008029DOI Listing
April 2009

Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair.

FASEB J 2009 Mar 10;23(3):813-22. Epub 2008 Nov 10.

UMR 7561 CNRS-Université Henri Poincaré Nancy 1, Faculté de Médecine, BP 184, 54505 Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.1096/fj.08-118166DOI Listing
March 2009

Thermodynamic insights into the structural basis governing the donor substrate recognition by human beta1,4-galactosyltransferase 7.

Biochem J 2009 Mar;418(3):605-14

Physiopathologie et Pharmacologie Articulaires, Unité Mixte de Recherche CNRS-UHP 7561, Nancy Université, Faculté de Médecine, BP 184 Vandoeuvre-Les-Nancy, France.

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http://biochemj.org/lookup/doi/10.1042/BJ20081093
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http://dx.doi.org/10.1042/BJ20081093DOI Listing
March 2009

Local induction of heat shock protein 70 (Hsp70) by proteasome inhibition confers chondroprotection during surgically induced osteoarthritis in the rat knee.

Biomed Mater Eng 2008 ;18(4-5):253-60

Physiopathologie et Pharmacologie Articulaires, UMR 7561 CNRS - Nacny Universite, Vandoeuvre les Nancy, France.

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February 2009

Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis.

Arthritis Res Ther 2008 16;10(1):R6. Epub 2008 Jan 16.

Laboratoire de Physiopathologie et Pharmacologie Articulaires (LPPA), UMR 7561 CNRS-Nancy Université, avenue de la forêt de Haye, BP 184, 54505 Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.1186/ar2354DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374462PMC
July 2008

Effect of alginate culture and mechanical stimulation on cartilaginous matrix synthesis of rat dedifferentiated chondrocytes.

Biomed Mater Eng 2008 ;18(1 Suppl):S47-54

Groupe Ingénierie Cellulaire et Tissulaire, UMR7563 CNRS-UHP-INPL LEMTA et IFR 111, Faculté de Médecine, Vandoeuvre-lès-Nancy, France.

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June 2008

Interaction of the electrophilic ketoprofenyl-glucuronide and ketoprofenyl-coenzyme A conjugates with cytosolic glutathione S-transferases.

Drug Metab Dispos 2008 Feb 25;36(2):260-7. Epub 2007 Oct 25.

Laboratoire d'Ingénierie Moléculaire et Biochimie Pharmacologique, Institut Jean Barriol FR Centre National de la Recherche Scientifique 2843, Université Paul Verlaine-Metz, Metz, France.

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http://dx.doi.org/10.1124/dmd.107.016808DOI Listing
February 2008

Identification of aspartic acid and histidine residues mediating the reaction mechanism and the substrate specificity of the human UDP-glucuronosyltransferases 1A.

J Biol Chem 2007 Dec 23;282(50):36514-24. Epub 2007 Oct 23.

UMR 7561, Faculté de Médecine and UMR 7036, Faculté des Sciences, CNRS-Université Henri Poincaré Nancy 1, 54505 Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.1074/jbc.M703107200DOI Listing
December 2007

Hyaluronate-covered nanoparticles for the therapeutic targeting of cartilage.

Biomacromolecules 2007 Dec 27;8(12):3879-85. Epub 2007 Nov 27.

Laboratoire de Chimie Physique Macromoléculaire, UMR CNRS-INPL 7568, BP 20451, 54001 Nancy Cedex, France.

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http://pubs.acs.org/doi/abs/10.1021/bm700836y
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http://dx.doi.org/10.1021/bm700836yDOI Listing
December 2007

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.

FEBS J 2007 Mar 29;274(5):1256-64. Epub 2007 Jan 29.

UMR 7561 CNRS, Université Henri Poincaré-Nancy I, Faculté de Médecine, F-54505 Vandoeuvre-lès-Nancy, France.

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http://doi.wiley.com/10.1111/j.1742-4658.2007.05670.x
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http://dx.doi.org/10.1111/j.1742-4658.2007.05670.xDOI Listing
March 2007

Irreversible inhibition of glucose-6-phosphate dehydrogenase by the coenzyme A conjugate of ketoprofen: a key to oxidative stress induced by non-steroidal anti-inflammatory drugs?

Biochem Pharmacol 2007 Feb 1;73(3):405-16. Epub 2006 Oct 1.

UMR 7561 CNRS-UHP, Physiopathologie et Pharmacologie Articulaires, Faculté de Médecine, BP 184, F-54505 Vandoeuvre les Nancy, France.

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http://dx.doi.org/10.1016/j.bcp.2006.09.026DOI Listing
February 2007

Increased apoptosis in rat osteoarthritic cartilage corresponds to degenerative chondral lesions and concomitant expression of caspase-3.

Biorheology 2006;43(3,4):403-12

Unité Mixte de Recherche 7561, CNRS - Université Nancy 1, Faculté de Médecine, Avenue de la Forêt de Haye, BP184, F-54505 Vandoeuvre lès Nancy, France.

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November 2006

Age-related quantitative MRI changes in healthy cartilage: preliminary results.

Biorheology 2006;43(3,4):547-51

Department of Pharmacology, Faculté de Médecine, UMR 7561 CNRS University Nancy I, Avenue de la Forêt de Haye, 54505 Vandoeuvre lès Nancy, France.

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November 2006

Effect of peroxisome proliferator activated receptor (PPAR)gamma agonists on prostaglandins cascade in joint cells.

Biorheology 2006;43(3,4):561-75

Laboratoire de Physiopathologie et Pharmacologie Articulaires, UMR 7561 CNRS-UHP, Nancy, France.

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November 2006

Establishment of a reliable method for direct proteome characterization of human articular cartilage.

Mol Cell Proteomics 2006 Oct 9;5(10):1984-95. Epub 2006 May 9.

Laboratoire de Physiopathologie et Pharmacologie Articulaires, Faculté de Médecine, Unité Mixte de Recherche, UMR, 7561 CNRS-Université Henry Poincaré, UHP 54505, Vandoeuvre-lès-Nancy Cedex, France.

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http://www.mcponline.org/lookup/doi/10.1074/mcp.T600007-MCP2
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http://dx.doi.org/10.1074/mcp.T600007-MCP200DOI Listing
October 2006

[Chondrocyte glycosyltransferases: new pharmacological targets for degenerative diseases of articular cartilage?].

Bull Acad Natl Med 2006 Oct;190(7):1385-97; discussion 1397-8, 1475-7

Physiopathologie et Pharmacologie Articulaires, UMR 7561 CNRS--Université Henri Poincaré--Nancy-1, Faculté de Médecine, BP 184, F-54505 Vandeouvre-lès-Nancy.

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October 2006

[Leptin: a link between obesity and osteoarthritis?].

Bull Acad Natl Med 2006 Oct;190(7):1421-35; discussion 1435-7, 1475-7

Physiopathologie et pharmacologie articulaires, Faculté de médecine, avenue de la forêt de Haye, BP 184, 54505, Vandceuvre les Nancy.

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October 2006

Evidence of calcium-dependent pathway in the regulation of human beta1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis.

FASEB J 2006 Aug 28;20(10):1692-4. Epub 2006 Jun 28.

UMR CNRS 7561-Université Henri Poincaré Nancy 1, Faculté de Médecine, BP 184, Vandoeuvre-lès-Nancy 54505, France.

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http://dx.doi.org/10.1096/fj.05-5073fjeDOI Listing
August 2006

New physically and chemically crosslinked hyaluronate (HA)-based hydrogels for cartilage repair.

J Biomed Mater Res A 2006 Feb;76(2):416-24

Laboratoire de Chimie Physique Macromoléculaire, UMR CNRS-INPL 7568, Groupe ENSIC, BP 451, 54001 Nancy Cedex, France.

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http://dx.doi.org/10.1002/jbm.a.30536DOI Listing
February 2006

Gene transfer with HSP 70 in rat chondrocytes confers cytoprotection in vitro and during experimental osteoarthritis.

FASEB J 2006 Jan;20(1):65-75

Unité Mixte de Recherches 7561, Centre National de la Recherche Scientifique-Université Henri Poincaré Nancy 1, Faculté de Médecine, Vandoeuvre lès Nancy, France.

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http://dx.doi.org/10.1096/fj.04-2889comDOI Listing
January 2006

Macroscopic and microscopic features of synovial membrane inflammation in the osteoarthritic knee: correlating magnetic resonance imaging findings with disease severity.

Arthritis Rheum 2005 Nov;52(11):3492-501

Hopitaux de Brabois, Centre Hospitalo-Universitaire de Nancy, and Unité Mixte de Recherches (UMR) 7561 CNRS-Université Nancy I, 54511 Vandoeuvre-les-Nancy, France.

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http://dx.doi.org/10.1002/art.21373DOI Listing
November 2005

[Chondrocyte mecanobiology. Application in cartilage tissue engineering].

Bull Acad Natl Med 2005 Nov;189(8):1803-14; discussion 1814-6

Mécanique et Ingénierie Cellulaire et Tissulaire, LEMTA UMR INPL CNRS 7563 et IFR 111 Bioingénierie, Faculté de Médecine, 54505 Vandoeuvre-lés-Nancy Cedex.

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November 2005

Uncoupling of oxidative phosphorylation and Smac/DIABLO release are not sufficient to account for induction of apoptosis by sulindac sulfide in human colorectal cancer cells.

Int J Oncol 2005 Apr;26(4):1069-77

Laboratoire de Physiopathologie et Pharmacologie Articulaires, UMR 7561 CNRS-UHP, Faculté de Médecine, Université Henri Poincaré, 54 505 Vandoeuvre-lès-Nancy cedex, France.

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April 2005

Effect of proteoglycan depletion on T2 mapping in rat patellar cartilage.

Radiology 2005 Jan 24;234(1):162-70. Epub 2004 Nov 24.

Department of Pharmacology, Physiopathologie et Pharmacologie Articulaires (UMR 7561), CNRS-Université Henri Poincaré Nancy I, Faculté de Médecine, BP 184, Avenue de la Forêt de Haye, F 54505 Vandoeuvre les Nancy, France.

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http://pubs.rsna.org/doi/10.1148/radiol.2341030394
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http://dx.doi.org/10.1148/radiol.2341030394DOI Listing
January 2005

Elucidation of the mechanism of inhibition of cyclooxygenases by acyl-coenzyme A and acylglucuronic conjugates of ketoprofen.

Biochem Pharmacol 2004 Nov;68(10):1957-69

UMR 7561 CNRS-UHP, Physiopathologie et Pharmacologie Articulaires, Faculté de Médecine-BP 184, F-54505 Vandoeuvre les Nancy, France.

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http://dx.doi.org/10.1016/j.bcp.2004.07.015DOI Listing
November 2004

[Therapeutic advances with coxibs: few certainties and a lot of doubts].

Therapie 2004 Mar-Apr;59(2):207-11

Laboratoire de Pharmacologie et UMR 7561 CNRS-UHP, Faculté de Médecine de Nancy, Vandoeuvre-lès-Nancy, France.

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October 2004

The ANKH gene and familial calcium pyrophosphate dihydrate deposition disease.

Joint Bone Spine 2004 Sep;71(5):365-8

Laboratoire de Physiopathologie et Pharmacologie Articulaires, UMR 7561 CNRS-UHP, Faculté de Médecine, 54505 Vandoeuvre Lès Nancy, France.

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http://dx.doi.org/10.1016/j.jbspin.2004.01.011DOI Listing
September 2004

15-Deoxy-delta(12,14)-prostaglandin J(2) inhibits IL-1beta-induced IKK enzymatic activity and IkappaBalpha degradation in rat chondrocytes through a PPARgamma-independent pathway.

FEBS Lett 2004 Aug;572(1-3):33-40

Laboratoire de Pharmacologie, UMR 7561 CNRS-Université, Henri Poincaré Nancy I, Faculté de Médecine, 54505 Vandoeuvre-Lès-Nancy, France.

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http://dx.doi.org/10.1016/j.febslet.2004.06.090DOI Listing
August 2004

[Pharmacology and classification of cyclooxygenase inhibitors].

Gastroenterol Clin Biol 2004 Apr;28 Spec No 3:C7-17

Laboratoire de Pharmacologie et UMR 7561 CNRS-UHP Faculté de Médecine de Nancy, Vandoeuvre-lès-Nancy.

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April 2004

Gene therapy in cartilage using electroporation.

Joint Bone Spine 2003 Dec;70(6):480-2

UMR 7561 CNRS, Laboratoire de pharmacologie, faculté de médecine de Nancy, Université Nancy I, avenue de la Foret-de-Haye BP 184, 54505 Vandoeuvre-les-Nancy, France.

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December 2003

Evidence for a key role of leptin in osteoarthritis.

Arthritis Rheum 2003 Nov;48(11):3118-29

CNRS, Vandoeuvre les Nancy, France.

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http://dx.doi.org/10.1002/art.11303DOI Listing
November 2003

The human UDP-glucuronosyltransferases: structural aspects and drug glucuronidation.

Drug Metab Rev 2003 Nov;35(4):287-303

UMR 7561 CNRS-University Henri Poincaré-Nancy I, Faculté de Médecine, Vandoeuvre-lés-Nancy, France.

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http://dx.doi.org/10.1081/DMR-120026397 DOI Listing
November 2003

The functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif.

J Biol Chem 2003 Aug 6;278(34):32219-26. Epub 2003 Jun 6.

UMR 7561 CNRS-Université Henri Poincaré Nancy 1, Faculté de Médecine, 54505 Vandoeuvre-lès-Nancy, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M207899200
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http://dx.doi.org/10.1074/jbc.M207899200DOI Listing
August 2003

Effects of antiinflammatory drugs on arthritic cartilage: a high-frequency quantitative ultrasound study in rats.

Arthritis Rheum 2003 Jun;48(6):1594-601

LIP, Unité Mixte de Recherches (UMR) 7623 CNRS-Université Paris VI, Paris, France.

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http://doi.wiley.com/10.1002/art.11023
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http://dx.doi.org/10.1002/art.11023DOI Listing
June 2003

Direct gene transfer into rat articular cartilage by in vivo electroporation.

FASEB J 2003 May;17(8):829-35

Unité Mixte de Recherches 7561, Centre National de la Recherche Scientifique-Université Henri Poincaré Nancy 1, Faculté de Médecine, Avenue de la Forêt de Haye, BP184, F-54505 Vandoeuvre lès Nancy, France.

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http://dx.doi.org/10.1096/fj.02-0518comDOI Listing
May 2003

Nitric oxide (NO) and cartilage metabolism: NO effects are modulated by superoxide in response to IL-1.

Biorheology 2002 ;39(1-2):201-14

Laboratoire de Pharmacologie et UMR 7561 CNRS-UHP, Faculté de Médecine, Vandoeuvre-lès-Nancy, France.

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October 2002

The in situ up-regulation of chondrocyte interleukin-1-converting enzyme and interleukin-18 levels in experimental osteoarthritis is mediated by nitric oxide.

Arthritis Rheum 2002 Oct;46(10):2637-47

Osteoarthritis Research Unit, Hôpital Notre-Dame, Centre hospitalier de l'Université de Montréal, 1560 rue Sherbrooke East, Montreal, Quebec H2L 4M1, Canada.

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http://dx.doi.org/10.1002/art.10518DOI Listing
October 2002

The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues.

J Biol Chem 2002 Jul 1;277(28):25439-45. Epub 2002 May 1.

UMR 7561 CNRS, Université Henri Poincaré Nancy 1, Faculté de Médecine, 54505 Vandoeuvre-lès-Nancy, France.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M201912200
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http://dx.doi.org/10.1074/jbc.M201912200DOI Listing
July 2002

Drug transport into the mammalian brain: the nasal pathway and its specific metabolic barrier.

J Drug Target 2002 Jun;10(4):285-96

Laboratoire de Pharmacologie, UMR No 7561 CNRS-Université Henri-Poincaré-Nancy 1, Faculté de Médecine, Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.1080/713714452 DOI Listing
June 2002

Limitation of the in vitro whole blood assay for predicting the COX selectivity of NSAIDs in clinical use.

Br J Clin Pharmacol 2002 Mar;53(3):255-65

Département de Pharmacologie Clinique, Centre Hospitalier Universitaire, UMR 7561, Centre National de la Recherche Scientifique-Université Henri Poincaré Nancy 1, Vandoeuvre lès Nancy, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874310PMC
http://dx.doi.org/10.1046/j.0306-5251.2001.01533.xDOI Listing
March 2002

PPAR-gamma ligands modulate effects of LPS in stimulated rat synovial fibroblasts.

Am J Physiol Cell Physiol 2002 Jan;282(1):C125-33

Laboratoire de Pharmacologie, Unite Mixte de Recherche Centre National de la Recherche Scientifique 7561, 54505 Vandoeuvre-lès-Nancy, France.

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http://dx.doi.org/10.1152/ajpcell.2002.282.1.C125DOI Listing
January 2002