Patrick N Harter

Patrick N Harter

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Patrick N Harter

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IGF1R Is a Potential New Therapeutic Target for HGNET-BCOR Brain Tumor Patients.

Int J Mol Sci 2019 Jun 21;20(12). Epub 2019 Jun 21.

Section of Pediatric Oncology, Children's Hospital, University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany.

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http://dx.doi.org/10.3390/ijms20123027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6627083PMC
June 2019

Influence of pregnancy on glioma patients.

Acta Neurochir (Wien) 2019 03 29;161(3):535-543. Epub 2019 Jan 29.

Department of Neurosurgery, Goethe University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00701-019-03823-6DOI Listing
March 2019

The physiological mTOR complex 1 inhibitor DDIT4 mediates therapy resistance in glioblastoma.

Br J Cancer 2019 Mar 12;120(5):481-487. Epub 2019 Feb 12.

Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.

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http://www.nature.com/articles/s41416-018-0368-3
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http://dx.doi.org/10.1038/s41416-018-0368-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461855PMC
March 2019

Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model.

Cancers (Basel) 2019 Mar 8;11(3). Epub 2019 Mar 8.

Experimental Neurosurgery, Department of Neurosurgery, Neuroscience Center, Goethe University Hospital, 60528 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/cancers11030333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468565PMC
March 2019

Fitting algorithms and baseline correction influence the results of non-invasive in vivo quantitation of 2-hydroxyglutarate with H-MRS.

NMR Biomed 2019 01 20;32(1):e4027. Epub 2018 Nov 20.

Klinikum der Johann Wolfgang Goethe-Universität Frankfurt, Institute of Neuroradiology, Frankfurt, Germany.

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http://dx.doi.org/10.1002/nbm.4027DOI Listing
January 2019

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors.

EMBO Mol Med 2018 09;10(9)

Molecular Signal Transduction Laboratories, Institute for Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn), University Medical Center of the Johannes Gutenberg University, Mainz, Germany

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http://dx.doi.org/10.15252/emmm.201708420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127886PMC
September 2018

Dexamethasone-induced leukocytosis is associated with poor survival in newly diagnosed glioblastoma.

J Neurooncol 2018 May 18;137(3):503-510. Epub 2018 Jan 18.

Department of Neurosurgery, University Hospital, Goethe University, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s11060-018-2761-4DOI Listing
May 2018

Doxycycline Impairs Mitochondrial Function and Protects Human Glioma Cells from Hypoxia-Induced Cell Death: Implications of Using Tet-Inducible Systems.

Int J Mol Sci 2018 May 17;19(5). Epub 2018 May 17.

Dr. Senckenberg Institute of Neurooncology, University Hospital Frankfurt, Goethe University, Schleusenweg 2-16, 60528 Frankfurt am Main, Germany.

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http://dx.doi.org/10.3390/ijms19051504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5983704PMC
May 2018

Tumorigenic and Antiproliferative Properties of the TALE-Transcription Factors MEIS2D and MEIS2A in Neuroblastoma.

Cancer Res 2018 04 30;78(8):1935-1947. Epub 2018 Jan 30.

Institute of Neurology (Edinger Institute), University Hospital Frankfurt, Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-1860DOI Listing
April 2018

New MR perfusion features in primary central nervous system lymphomas: pattern and prognostic impact.

J Neurol 2018 Mar 30;265(3):647-658. Epub 2018 Jan 30.

Institute of Neuroradiology, Goethe-University Hospital Frankfurt, Schleusenweg 2-16, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00415-018-8737-7DOI Listing
March 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Suppression of oxidative phosphorylation confers resistance against bevacizumab in experimental glioma.

J Neurochem 2018 02 8;144(4):421-430. Epub 2018 Jan 8.

Dr Senckenberg Institute of Neurooncology, Goethe University, Frankfurt, Germany.

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http://dx.doi.org/10.1111/jnc.14264DOI Listing
February 2018

Genetic heterogeneity of primary lesion and metastasis in small intestine neuroendocrine tumors.

Sci Rep 2018 02 28;8(1):3811. Epub 2018 Feb 28.

Department of Internal Medicine I, Johann Wolfgang Goethe-University Hospital, Theodor-Stern-Kai 7, 60590, Frankfurt, Germany.

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http://dx.doi.org/10.1038/s41598-018-22115-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830878PMC
February 2018

ASA404, a vascular disrupting agent, as an experimental treatment approach for brain tumors.

Oncol Lett 2017 Nov 28;14(5):5443-5451. Epub 2017 Aug 28.

Institute of Neurology (Edinger-Institute), Goethe-University, Frankfurt, Germany.

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http://dx.doi.org/10.3892/ol.2017.6832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652230PMC
November 2017

Bevacizumab for Patients with Recurrent Multifocal Glioblastomas.

Int J Mol Sci 2017 Nov 20;18(11). Epub 2017 Nov 20.

Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, 60528 Frankfurt, Germany.

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http://dx.doi.org/10.3390/ijms18112469DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5713435PMC
November 2017

Identification of intestinal ganglioneuromatosis leads to early diagnosis of MEN2B: role of rectal biopsy.

J Pediatr Surg 2017 Jul 17;52(7):1161-1165. Epub 2016 Nov 17.

Department of Pediatric Surgery and Pediatric Urology, Goethe University Hospital, Frankfurt, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2016.10.054DOI Listing
July 2017

Classification of meningiomas-advances and controversies.

Chin Clin Oncol 2017 Jul 4;6(Suppl 1):S2. Epub 2017 Jun 4.

Institute of Neurology (Edinger-Institute), Goethe University Frankfurt, Frankfurt am Main, Germany; German Cancer Consortium (DKTK), Partner site Frankfurt/Mainz, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.21037/cco.2017.05.02DOI Listing
July 2017

Bevacizumab as a last-line treatment for glioblastoma following failure of radiotherapy, temozolomide and lomustine.

Oncol Lett 2017 Jul 25;14(1):1141-1146. Epub 2017 May 25.

University Hospital and University Cancer Center, German Cancer Consortium (DKTK), Partner Site Frankfurt/Mainz, Frankfurt and German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany.

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http://dx.doi.org/10.3892/ol.2017.6251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494648PMC
July 2017

Perfusion MRI in the Evaluation of Suspected Glioblastoma Recurrence.

J Neuroimaging 2016 Jan-Feb;26(1):116-23. Epub 2015 Apr 24.

Institute of Neuroradiology, Goethe-University Hospital Frankfurt, Schleusenweg 2-16, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1111/jon.12247DOI Listing
January 2017

C5b-9 deposits on endomysial capillaries in non-dermatomyositis cases.

Neuromuscul Disord 2016 Apr-May;26(4-5):283-91. Epub 2016 Mar 3.

Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nmd.2016.02.014DOI Listing
January 2017

EGFRvIII mutations can emerge as late and heterogenous events in glioblastoma development and promote angiogenesis through Src activation.

Neuro Oncol 2016 12 10;18(12):1644-1655. Epub 2016 Jun 10.

Department of Biomedicine, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., T.T., K.V., J.A.H., J.V.J., R.J., H.S.S., L.L., T.D., P.Ø.E., R.B., H.M.); KG Jebsen Brain Tumor Research Center, University of Bergen, Norway (E.E., G.V.R., K.M.T., O.K., K.V., J.A.H., J.V.J., T.D., P. Ø.E., S.P.N., R.B., H.M.); Department of Clinical Science, University of Bergen, Norway (S.K.); Department of Oncology, Haukeland University Hospital, Bergen, Norway (S.K.); Norlux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (O.K., S.F., S.P.N., R.B.); Centre for Evolution and Cancer, The Institute of Cancer Research, London, UK (A.S.); Department of Clinical Pharmacy, Institute of Pharmacy, Ernst-Moritz-Arndt-University, Greifswald, Germany (S.F., C.A.R.); Department of Neurooncology, University Hospital Heidelberg, Germany (G.S., F.W.); Institute of Scientific Instruments, ASCR, Brno, Czech Republic (R.J.); Edinger-Intsitute, Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H.); Department of Pathology, Haukeland University Hospital, Bergen, Norway (J.A.H., H.M.); Department of Clinical Neurosciences, University of Cambridge, UK (S.G.P., C.W.); Statistics and Computational Biology Laboratory, University of Cambridge, UK (I.S.); Neuro Clinic, Haukeland University Hospital, Bergen, Norway; Department of Experimental Neurology, Charité - Universitätsmedizin Berlin, Germany (P.E.); Department of Systems Medicine, University of Rome «Tor Vergata», Rome, Italy (G.G.); INSERM U1029 - University of Bordeaux, Allée Geoffroy St. Hilaire, Pessac, France (T.D.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (M.L.-J., P. Ø.E.).

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http://dx.doi.org/10.1093/neuonc/now113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791772PMC
December 2016

FOXO3a orchestrates glioma cell responses to starvation conditions and promotes hypoxia-induced cell death.

Int J Oncol 2016 Dec 4;49(6):2399-2410. Epub 2016 Nov 4.

Dr. Senckenberg Institute of Neurooncology, Goethe University Hospital, Frankfurt, Germany.

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http://dx.doi.org/10.3892/ijo.2016.3760DOI Listing
December 2016

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence.

Acta Neuropathol 2016 09 27;132(3):479-81. Epub 2016 Jul 27.

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, 60528, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00401-016-1598-1DOI Listing
September 2016

Expression Profile of Sonic Hedgehog Pathway Members in the Developing Human Fetal Brain.

Biomed Res Int 2015 21;2015:494269. Epub 2015 Jul 21.

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, 60528 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1155/2015/494269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523658PMC
May 2016

ErbB2/HER2-Specific NK Cells for Targeted Therapy of Glioblastoma.

J Natl Cancer Inst 2016 May 6;108(5). Epub 2015 Dec 6.

Affiliations of authors:Georg-Speyer-Haus, Institute for Tumor Biology and Experimental Therapy, Frankfurt am Main , Germany (CZ, SG, KS, WSW); German Cancer Consortium (DKTK), partner site Frankfurt/Mainz , Germany (CZ, MCB, JPS, WSW); German Cancer Research Center (DKFZ), Heidelberg , Germany (CZ, MCB); Institute for Neurooncology (MCB, JPS), Edinger Institute (LJ, PZ, PNH, MM), Department of Neurology (PZ), and Institute of Neuroradiology (EH), Goethe University, Frankfurt am Main , Germany ; Institute for Transfusion Medicine, German Red Cross Blood Donation Service North-East and Medical Faculty Carl Gustav Carus, TU Dresden , Dresden , Germany (TT).

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http://dx.doi.org/10.1093/jnci/djv375DOI Listing
May 2016

Immunohistochemical Assessment of Phosphorylated mTORC1-Pathway Proteins in Human Brain Tumors.

PLoS One 2015 19;10(5):e0127123. Epub 2015 May 19.

German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127123PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437987PMC
April 2016

Downstream effects of plectin mutations in epidermolysis bullosa simplex with muscular dystrophy.

Acta Neuropathol Commun 2016 04 27;4(1):44. Epub 2016 Apr 27.

Institute of Neuropathology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054, Erlangen, Germany.

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http://dx.doi.org/10.1186/s40478-016-0314-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4847350PMC
April 2016

Autophagy-associated proteins BAG3 and p62 in testicular cancer.

Oncol Rep 2016 Mar 22;35(3):1629-35. Epub 2015 Dec 22.

Department of Urology, Goethe University Frankfurt/Main, Germany.

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http://dx.doi.org/10.3892/or.2015.4505DOI Listing
March 2016

Differential expression of vascular endothelial growth factor A, its receptors VEGFR-1, -2, and -3 and co-receptors neuropilin-1 and -2 does not predict bevacizumab response in human astrocytomas.

Neuro Oncol 2016 Feb 30;18(2):173-83. Epub 2015 Nov 30.

Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany (P.B., A.-E.B., M.D., P.Z., K.H., L.M., K.H.P., P.N.H., M.Mi.); Department of Neurosurgery, Goethe University, Frankfurt, Germany (K.F., V.S.); Dr. Senckenberg Institute of Neurooncology, University of Frankfurt am Main, Frankfurt am Main, Germany (K.F., O.B., J.P.S.); Department of Neuroradiology, University of Frankfurt am Main, Frankfurt am Main, Germany (E.H.); Department of Neurosurgery, University Hospital, Freiburg, Germany (M.Ma.); Cancer Consortium (DKTK), Heidelberg, Germany (O.B., J.P.S., K.H.P, P.N.H., M.Mi.); German Cancer Research Center (DKFZ), Heidelberg, Germany (O.B., J.P.S., K.H.P., P.N.H., M.Mi.); Department of Pathology, University of Heidelberg, Heidelberg, Germany (B.G.).

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http://dx.doi.org/10.1093/neuonc/nov288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4724185PMC
February 2016

Melanoma brain metastasis is independent of lactate dehydrogenase A expression.

Neuro Oncol 2015 Oct 19;17(10):1374-85. Epub 2015 Mar 19.

Department of Biomedicine, University of Bergen, Bergen, Norway (T.S., H.E., K.O.S., S.H., E.H., C.B.R., R.Bj., F.T.); Department of Clinical Medicine, University of Bergen, Bergen, Norway (T.S., M.L.-J.); Department of Neurosurgery, Haukeland University Hospital, Bergen, Norway (T.S., M.L.-J.); Edinger-Institute (Neurological Institute), Goethe-University Medical School, Frankfurt am Main, Germany (P.N.H., M.M.); Center for Nuclear Medicine/PET, Department of Oncology and Medical Physics, Haukeland University Hospital, Bergen, Norway (K.E.F.); Department of Dermatology, University Medical Center, Tübingen, Germany (B.W.); Department of Immunology, University of Tübingen, Tübingen, Germany (B.W.); Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen, Germany (R.Be.); Department of Diagnostic and Interventional Neuroradiology, University of Tübingen, Tübingen, Germany (B.B.); NorLux Neuro-Oncology Laboratory, Department of Oncology, Luxembourg Institute of Health, Luxembourg (R.Bj.).

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http://dx.doi.org/10.1093/neuonc/nov040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4578581PMC
October 2015

Antibody therapy to human L1CAM in a transgenic mouse model blocks local tumor growth but induces EMT.

Int J Cancer 2015 Mar 25;136(5):E326-39. Epub 2014 Sep 25.

Translational Immunology, D015, Tumor Immunology Programme German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29222DOI Listing
March 2015

Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas.

Neuropathol Appl Neurobiol 2015 Feb;41(2):e56-67

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1111/nan.12135DOI Listing
February 2015

Confounding factors in diagnostics of MGMT promoter methylation status in glioblastomas in stereotactic biopsies.

Stereotact Funct Neurosurg 2014 24;92(3):129-39. Epub 2014 Apr 24.

Department of Neurosurgery, Goethe University Frankfurt, Frankfurt/Main, Germany.

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http://dx.doi.org/10.1159/000360582DOI Listing
February 2015

β-Catenin-Gli1 interaction regulates proliferation and tumor growth in medulloblastoma.

Mol Cancer 2015 Feb 3;14:17. Epub 2015 Feb 3.

Institute of Neurology (Edinger-Institute), Johann Wolfgang Goethe-University Frankfurt, Medical School, Heinrich-Hoffmann-Straße 7, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1186/s12943-015-0294-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320815PMC
February 2015

Netrin-1 expression is an independent prognostic factor for poor patient survival in brain metastases.

PLoS One 2014 19;9(3):e92311. Epub 2014 Mar 19.

Edinger Institute, Institute of Neurology, University of Frankfurt am Main, Frankfurt am Main, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0092311PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960244PMC
November 2014

Analysis of cerebral angiogenesis in human glioblastomas.

Methods Mol Biol 2014 ;1135:187-203

Neurological Institute (Edinger Institute), Frankfurt University Medical School, Frankfurt, Germany.

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http://link.springer.com/content/pdf/10.1007%2F978-1-4939-03
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http://link.springer.com/10.1007/978-1-4939-0320-7_16
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http://dx.doi.org/10.1007/978-1-4939-0320-7_16DOI Listing
September 2014

Sustained focal antitumor activity of bevacizumab in recurrent glioblastoma.

Neurology 2014 Jul 13;83(3):227-34. Epub 2014 Jun 13.

From the Dr. Senckenberg Institute of Neurooncology (O.B., M.W.R., J.R., J.P.S.), Institute of Neurology (Edinger-Institute) (P.N.H., M.M.), Department of Neurosurgery (L.M.W.), and Institute of Neuroradiology (S.-J.Y., E.H.), University Hospital Frankfurt, Goethe University, Frankfurt; and German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ) (O.B., P.N.H., L.M.W., S.-J.Y., M.M., M.W.R., J.R., J.P.S., E.H.), Heidelberg, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000000594DOI Listing
July 2014

Benefit of tumor resection for recurrent glioblastoma.

J Neurooncol 2014 Apr 15;117(2):365-72. Epub 2014 Feb 15.

Department of Neurosurgery, University Hospital Frankfurt, Goethe University, Frankfurt, Germany,

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http://link.springer.com/content/pdf/10.1007/s11060-014-1397
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http://link.springer.com/10.1007/s11060-014-1397-2
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http://dx.doi.org/10.1007/s11060-014-1397-2DOI Listing
April 2014

The embryonic stem cell factor UTF1 serves as a reliable diagnostic marker for germinomas.

Pathology 2014 Apr;46(3):225-9

1Department of Neuropathology, University of Marburg 2Department of Neuropathology, Edinger Institute (Institute of Neurology), Goethe University, Frankfurt/Main 3Department of Neuropathology, Ruprecht-Karls-University of Heidelberg 4Department of Pathology, Klinikum Stuttgart 5Department of Neuropathology, Institute of Pathology and Neuropathology, Eberhard-Karls-University of Tuebingen, Germany.

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http://dx.doi.org/10.1097/PAT.0000000000000071DOI Listing
April 2014

Brain stem infarction associated with familial Mediterranean fever and central nervous system vasculitis.

Clin Exp Rheumatol 2013 May-Jun;31(3 Suppl 77):93-5. Epub 2013 May 27.

Department of Neurology, Goethe-University, Frankfurt am Main, Germany.

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November 2013

Anti-tissue factor (TF9-10H10) treatment reduces tumor cell invasiveness in a novel migratory glioma model.

Neuropathology 2013 Oct 5;33(5):515-25. Epub 2013 Feb 5.

Edinger Institute, Institute of Neurology, Goethe University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1111/neup.12018DOI Listing
October 2013

MR perfusion in and around the contrast-enhancement of primary CNS lymphomas.

J Neurooncol 2013 Aug 22;114(1):127-34. Epub 2013 May 22.

Institute of Neuroradiology, Goethe-University Hospital Frankfurt, University of Frankfurt, Schleusenweg 2-16, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s11060-013-1161-zDOI Listing
August 2013

EGFL7 ligates αvβ3 integrin to enhance vessel formation.

Blood 2013 04 5;121(15):3041-50. Epub 2013 Feb 5.

Molecular Signal Transduction Laboratory at the Institute of Microscopic Anatomy and Neurobiology, Focus Program Translational Neuroscience (FTN), Johannes Gutenberg University School of Medicine, Mainz, Germany.

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http://dx.doi.org/10.1182/blood-2011-11-394882DOI Listing
April 2013

Cardiac period 2 in myocardial ischemia: clinical implications of a light dependent protein.

Int J Biochem Cell Biol 2013 Mar 3;45(3):667-71. Epub 2013 Jan 3.

Department of Anesthesiology and Mucosal Inflammation Program, University of Colorado Denver, CO, USA.

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http://dx.doi.org/10.1016/j.biocel.2012.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761885PMC
March 2013

MicroRNA-145 targets the metalloprotease ADAM17 and is suppressed in renal cell carcinoma patients.

Neoplasia 2013 Feb;15(2):218-30

Pharmazentrum Frankfurt/Zentrum für Arzneimittelforschung, Entwicklung und Sicherheit, Goethe University Hospital, Frankfurt am Main, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579323PMC
http://dx.doi.org/10.1593/neo.121222DOI Listing
February 2013

Fermented mistletoe extract as a multimodal antitumoral agent in gliomas.

Evid Based Complement Alternat Med 2012 22;2012:501796. Epub 2012 Oct 22.

Laboratory for Molecular Neuro-Oncology, Hertie Institute for Clinical Brain Research and Center Neurology, University of Tübingen, Otfried-Müller-Straße 27, 72076 Tübingen, Germany.

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http://dx.doi.org/10.1155/2012/501796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485514PMC
November 2012

Angiopoietin-2 promotes myeloid cell infiltration in a β₂-integrin-dependent manner.

Blood 2011 Nov 25;118(18):5050-9. Epub 2011 Aug 25.

Edinger Institute/Institute of Neurology, Frankfurt University Medical School, Frankfurt, Germany.

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http://dx.doi.org/10.1182/blood-2011-03-343293DOI Listing
November 2011

Macrophage migration inhibitory factor (MIF) expression in human malignant gliomas contributes to immune escape and tumour progression.

Acta Neuropathol 2011 Sep 21;122(3):353-65. Epub 2011 Jul 21.

Institute of Neurology (Edinger Institute), Goethe University, Heinrich-Hoffmann-Strasse 7, 60528, Frankfurt, Germany.

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http://dx.doi.org/10.1007/s00401-011-0858-3DOI Listing
September 2011

Problems and challenges in the diagnosis of vertical infection with human cytomegalovirus (CMV): lessons from two accidental cases.

J Clin Virol 2011 Aug;51(4):285-8

Institut für Medizinische Virologie, Klinikum der J W Goethe-Universität, Paul Ehrlich Str. 40, D-60596, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1016/j.jcv.2011.05.007DOI Listing
August 2011