Patrick Michl

Patrick Michl

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Patrick Michl

Patrick Michl

Publications by authors named "Patrick Michl"

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Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms.

Gut 2019 05 19;68(5):854-865. Epub 2019 Jan 19.

Medical Department 1, University Hospital Dresden, Technische Universität Dresden (TU Dresden), Dresden, Germany.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2018-317619
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http://dx.doi.org/10.1136/gutjnl-2018-317619DOI Listing
May 2019

[Acute Abdominal Pain: Hospital Admission or Not - And What Happens Then?]

Dtsch Med Wochenschr 2019 05 13;144(10):670-676. Epub 2019 May 13.

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http://dx.doi.org/10.1055/a-0759-8022DOI Listing
May 2019

Brain metastases in patients with neuroendocrine neoplasms: risk factors and outcome.

BMC Cancer 2019 Apr 16;19(1):362. Epub 2019 Apr 16.

Department of Gastroenterology and Endocrinology, University Hospital Marburg, Baldinger Strasse, 35043, Marburg, Germany.

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http://dx.doi.org/10.1186/s12885-019-5559-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469052PMC
April 2019

Stromal biology and therapy in pancreatic cancer: ready for clinical translation?

Gut 2019 01 3;68(1):159-171. Epub 2018 Sep 3.

Department of Gastroenterology, Endocrinology, Metabolism and Infectiology, University Hospital Marburg, UKGM, Philipps University Marburg, Marburg, Germany.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2018-316451
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http://dx.doi.org/10.1136/gutjnl-2018-316451DOI Listing
January 2019

High frequency of secondary, but not primary ocular manifestations of inflammatory bowel disease in patients treated at a tertiary care center.

Eur J Gastroenterol Hepatol 2018 12;30(12):1502-1506

Department of Ophthalmology, Martin Luther University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1097/MEG.0000000000001248DOI Listing
December 2018

Genome-wide association study identifies inversion in the locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

Gut 2018 10 28;67(10):1855-1863. Epub 2017 Jul 28.

Department of Molecular and Cell Biology, Center for Exocrine Disorders, Boston University Henry M. Goldman School of Dental Medicine, Boston, Massachusetts, USA.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2017-314454
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http://dx.doi.org/10.1136/gutjnl-2017-314454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145291PMC
October 2018

Therapeutic targeting of tumor-associated macrophages in pancreatic neuroendocrine tumors.

Int J Cancer 2018 10;143(7):1806-1816

Department of Internal Medicine I, Martin Luther University Halle-Wittenberg, Halle, Saale, Germany.

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http://dx.doi.org/10.1002/ijc.31562DOI Listing
October 2018

Overcoming immune evasion in pancreatic cancer: the combination matters.

Gut 2018 06 7;67(6):997-999. Epub 2017 Dec 7.

Department of Internal Medicine I, Martin-Luther-University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1136/gutjnl-2017-315443DOI Listing
June 2018

Therapeutic developments in pancreatic cancer: current and future perspectives.

Nat Rev Gastroenterol Hepatol 2018 06;15(6):333-348

Department of Molecular and Clinical Cancer Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1038/s41575-018-0005-xDOI Listing
June 2018

The Role of Cytotoxic Chemotherapy in Advanced Pancreatic Neuroendocrine Tumors.

Digestion 2017 21;96(2):67-75. Epub 2017 Jul 21.

Department of Internal Medicine I, Martin-Luther University Halle/Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1159/000477800DOI Listing
May 2018

Esophageal Cancer: New Insights into a Heterogenous Disease.

Digestion 2017 7;95(4):253-261. Epub 2017 Apr 7.

Department of Internal Medicine I, Martin-Luther University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1159/000464130DOI Listing
April 2018

Family planning in inflammatory bowel disease: childlessness and disease-related concerns among female patients.

Eur J Gastroenterol Hepatol 2018 Mar;30(3):310-315

Department of Internal Medicine I, Martin-Luther-University of Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1097/MEG.0000000000001037DOI Listing
March 2018

Sexual Dysfunction in Patients With Inflammatory Bowel Disease is not just a Matter of Quality of Life.

J Crohns Colitis 2018 Mar;12(4):505-506

Department of Internal Medicine I, Martin-Luther-University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1093/ecco-jcc/jjx164DOI Listing
March 2018

Severe Colitis After an Alcohol Enema.

Am J Gastroenterol 2018 02;113(2):172

Department of Internal Medicine I, Martin Luther University Halle-Wittenberg, Halle (Saale), Germany.

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http://dx.doi.org/10.1038/ajg.2017.460DOI Listing
February 2018

Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer.

Gut 2017 07 24;66(7):1278-1285. Epub 2016 Mar 24.

Department of Internal Medicine I, Martin Luther University, Halle, Germany.

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http://dx.doi.org/10.1136/gutjnl-2015-310049DOI Listing
July 2017

Impact of Therapy Sequence with Alkylating Agents and MGMT Status in Patients with Advanced Neuroendocrine Tumors.

Anticancer Res 2017 05;37(5):2491-2500

Department of Gastroenterology and Endocrinology, Philipps-University, Marburg, Germany.

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http://dx.doi.org/10.21873/anticanres.11590DOI Listing
May 2017

Targeted therapy of pancreatic cancer: biomarkers are needed.

Lancet Oncol 2017 04 2;18(4):421-422. Epub 2017 Mar 2.

Department of Internal Medicine, Martin-Luther University Halle-Wittenberg, 06120 Halle, Germany.

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http://dx.doi.org/10.1016/S1470-2045(17)30087-6DOI Listing
April 2017

Acromegaly in a patient with a pulmonary neuroendocrine tumor: case report and review of current literature.

BMC Res Notes 2016 Jun 27;9:326. Epub 2016 Jun 27.

Department of Gastroenterology, Endocrinology and Metabolism, Philipps-University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1186/s13104-016-2132-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924317PMC
June 2016

miRNA dynamics in tumor-infiltrating myeloid cells modulating tumor progression in pancreatic cancer.

Oncoimmunology 2016 Jun 9;5(6):e1160181. Epub 2016 May 9.

Department of Gastroenterology and Endocrinology, University Hospital, Philipps-University, Marburg, Germany; Department of Internal Medicine I, Martin-Luther-University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1080/2162402X.2016.1160181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938301PMC
June 2016

Additive antitumour response to the rabbit VX2 hepatoma by combined radio frequency ablation and toll like receptor 9 stimulation.

Gut 2016 Jan 18;65(1):134-43. Epub 2014 Dec 18.

Department of Medicine 1, University Hospital Erlangen-Nuremberg, Erlangen, Germany Division of Gastroenterology, University Hospital, Philipps-University Marburg, Marburg, Germany.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2014-308286
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http://dx.doi.org/10.1136/gutjnl-2014-308286DOI Listing
January 2016

CUX1: a modulator of tumour aggressiveness in pancreatic neuroendocrine neoplasms.

Endocr Relat Cancer 2014 23;21(6):879-90. Epub 2014 Sep 23.

Departments of GastroenterologyEndocrinology and MetabolismSurgeryPhilipps-University Marburg, Baldingerstraße, 35043 Marburg, GermanyDepartment of PathologyEberhard-Karls-University Tübingen, Tübingen, GermanyDepartment of PathologyUniversity Hospital Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1530/ERC-14-0152DOI Listing
June 2015

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.

Gastroenterology 2014 Nov 12;147(5):1119-33.e4. Epub 2014 Aug 12.

Stem Cells and Cancer Group, Spanish National Cancer Research Centre (CNIO), Madrid, Spain; Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, UK. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2014.08.002DOI Listing
November 2014

Desmoplasia and chemoresistance in pancreatic cancer.

Cancers (Basel) 2014 Oct 21;6(4):2137-54. Epub 2014 Oct 21.

Department of Clinical Science, Intervention and Technology (CLINTEC), Karolinska Institutet, SE-141 52 Huddinge, Sweden.

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http://dx.doi.org/10.3390/cancers6042137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4276960PMC
October 2014

Paraneoplastic brainstem encephalitis in a patient with exceptionally long course of a metastasized neuroendocrine rectum neoplasm.

BMC Cancer 2014 Sep 22;14:691. Epub 2014 Sep 22.

Department of Gastroenterology, Endocrinology and Metabolism, Philipps-University Marburg, Baldingerstrasse, 35043 Marburg, Germany.

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http://dx.doi.org/10.1186/1471-2407-14-691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4180833PMC
September 2014

The role of CUX1 in antagonizing NF-κB signaling in TAMs.

Oncoimmunology 2014 27;3:e28270. Epub 2014 Mar 27.

Department of Gastroenterology, Endocrinology and Metabolism; Philipps-University Marburg; Marburg, Germany.

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http://dx.doi.org/10.4161/onci.28270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4063149PMC
March 2014

Emerging concepts in pancreatic cancer medicine: targeting the tumor stroma.

Onco Targets Ther 2013 Dec 18;7:33-43. Epub 2013 Dec 18.

Department of Gastroenterology, Endocrinology, Infectiology and Metabolism, Philipps University Marburg, Marburg, Germany.

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http://www.dovepress.com/emerging-concepts-in-pancreatic-can
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http://dx.doi.org/10.2147/OTT.S38111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3872146PMC
December 2013

Claudin-4-targeted optical imaging detects pancreatic cancer and its precursor lesions.

Gut 2013 Jul 7;62(7):1034-43. Epub 2012 Jun 7.

Department of Gastroenterology, Endocrinology and Metabolism, Philipps University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1136/gutjnl-2012-302577DOI Listing
July 2013

Current concepts and novel targets in advanced pancreatic cancer.

Gut 2013 Feb 30;62(2):317-26. Epub 2012 Oct 30.

Department of Gastroenterology, Endocrinology and Metabolism, Philipps University Marburg, Baldinger Strasse, Marburg 35043, Germany.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2012-303588
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http://dx.doi.org/10.1136/gutjnl-2012-303588DOI Listing
February 2013

WNT5A-NFAT signaling mediates resistance to apoptosis in pancreatic cancer.

Neoplasia 2013 Jan;15(1):11-22

Department of Gastroenterology and Endocrinology, University Hospital, Philipps-University, D-35043 Marburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556935PMC
http://dx.doi.org/10.1593/neo.121312DOI Listing
January 2013

Improving drug delivery to pancreatic cancer: breaching the stromal fortress by targeting hyaluronic acid.

Gut 2012 Oct 3;61(10):1377-9. Epub 2012 Jun 3.

Department of Gastroenterology, Endocrinology, Metabolism and Infectiology, University of Marburg, Baldinger Strasse, D-35043 Marburg, Germany.

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http://gut.bmj.com/lookup/doi/10.1136/gutjnl-2012-302604
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http://dx.doi.org/10.1136/gutjnl-2012-302604DOI Listing
October 2012

Targeting cathepsins: a new glimmer of hope for pancreatic cancer therapy?

Authors:
Patrick Michl

Gut 2012 Jun 27;61(6):790-1. Epub 2012 Jan 27.

Department of Gastroenterology, University of Marburg, Baldinger Strasse, Marburg D-35043, Germany.

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http://dx.doi.org/10.1136/gutjnl-2011-301816DOI Listing
June 2012

Medical treatment of gastroenteropancreatic neuroendocrine tumors.

Cancers (Basel) 2012 Feb 8;4(1):113-29. Epub 2012 Feb 8.

Department of Gastroenterology, University Hospital Marburg, Baldinger Strasse, Marburg D-35043, Germany.

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http://dx.doi.org/10.3390/cancers4010113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3712673PMC
February 2012

Stromal biology and therapy in pancreatic cancer.

Gut 2011 Jun 21;60(6):861-8. Epub 2010 Oct 21.

Li Ka Shing Centre, Cambridge Research Institute, Cancer Research UK, Cambridge, UK.

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http://gut.bmj.com/cgi/doi/10.1136/gut.2010.226092
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http://dx.doi.org/10.1136/gut.2010.226092DOI Listing
June 2011

Screening technologies for target identification in pancreatic cancer.

Cancers (Basel) 2010 Dec 29;3(1):79-90. Epub 2010 Dec 29.

Department of Gastroenterology and Endocrinology, University Hospital, Philipps-University Marburg, Baldinger Strasse, D-35043 Marburg, Germany.

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http://dx.doi.org/10.3390/cancers3010079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3756350PMC
December 2010

Liver-specific therapies for metastases of neuroendocrine pancreatic tumors.

World J Hepatol 2010 Oct;2(10):367-73

Volker Fendrich, Nils Habbe, Detlef Klaus Bartsch, Department of Surgery, Philipps-University, Marburg D-35043, Germany.

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http://dx.doi.org/10.4254/wjh.v2.i10.367DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2998945PMC
October 2010

Simultaneous onset of ulcerative colitis and disseminated pyoderma gangrenosum.

Case Rep Gastroenterol 2007 Oct 12;1(1):110-5. Epub 2007 Oct 12.

Division of Gastroenterology and Endocrinology, IBD Centre, Philipps University Marburg, Marburg, Germany.

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http://dx.doi.org/10.1159/000108637DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073797PMC
October 2007

Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway.

EMBO J 2006 Aug 27;25(15):3714-24. Epub 2006 Jul 27.

Translational Genome Research Group, Department of Internal Medicine I, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1038/sj.emboj.7601246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538549PMC
August 2006

CUTL1 is phosphorylated by protein kinase A, modulating its effects on cell proliferation and motility.

J Biol Chem 2006 Jun 30;281(22):15138-44. Epub 2006 Mar 30.

Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, United Kingdom.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M600908200
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http://dx.doi.org/10.1074/jbc.M600908200DOI Listing
June 2006

Evidence-based diagnosis and staging of pancreatic cancer.

Best Pract Res Clin Gastroenterol 2006 Apr;20(2):227-51

Department of Internal Medicine I, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1016/j.bpg.2005.10.005DOI Listing
April 2006

CUTL1: a key mediator of TGFbeta-induced tumor invasion.

Cell Cycle 2006 Jan 16;5(2):132-4. Epub 2006 Jan 16.

Abteilung Innere Medizin I, Klinikum der Universität Ulm, Ulm, Germany.

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http://dx.doi.org/10.4161/cc.5.2.2311DOI Listing
January 2006

CUTL1 is a target of TGF(beta) signaling that enhances cancer cell motility and invasiveness.

Cancer Cell 2005 Jun;7(6):521-32

Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, United Kingdom.

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http://dx.doi.org/10.1016/j.ccr.2005.05.018DOI Listing
June 2005

Claudin-4 expression decreases invasiveness and metastatic potential of pancreatic cancer.

Cancer Res 2003 Oct;63(19):6265-71

Department of Internal Medicine I, University Hospital, University of Ulm, Robert-Koch-Strasse 8, 89081 Ulm, Germany.

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October 2003