Patrick McArdle

Patrick McArdle

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Patrick McArdle

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Sex differences in Parkinson's disease presentation and progression.

Parkinsonism Relat Disord 2019 Dec 23;69:48-54. Epub 2019 Oct 23.

Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1016/j.parkreldis.2019.10.019DOI Listing
December 2019

Visible-light unmasking of heterocyclic quinone methide radicals from alkoxyamines.

Chem Commun (Camb) 2019 Dec 20;55(97):14665-14668. Epub 2019 Nov 20.

School of Chemistry, National University of Ireland Galway, University Road, Galway, H91 TK33, Ireland and Department of Pharmacy, School of Life Sciences, Pharmacy and Chemistry, Kingston University, Penrhyn Road, Kingston upon Thames, KT1 2EE, UK.

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http://dx.doi.org/10.1039/c9cc08261aDOI Listing
December 2019

Incorporating Morpholine and Oxetane into Benzimidazolequinone Antitumor Agents: The Discovery of 1,4,6,9-Tetramethoxyphenazine from Hydrogen Peroxide and Hydroiodic Acid-Mediated Oxidative Cyclizations.

J Org Chem 2019 Aug 24;84(15):9811-9818. Epub 2019 Jul 24.

Department of Pharmacy, School of Life Sciences, Pharmacy and Chemistry , Kingston University , Penrhyn Road , Kingston upon Thames KT1 2EE , U.K.

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http://dx.doi.org/10.1021/acs.joc.9b01427DOI Listing
August 2019

Publisher Correction: Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2019 Jul;51(7):1192-1193

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-019-0449-0DOI Listing
July 2019

Genetics of the thrombomodulin-endothelial cell protein C receptor system and the risk of early-onset ischemic stroke.

PLoS One 2018 1;13(11):e0206554. Epub 2018 Nov 1.

University of Maryland School of Medicine, Baltimore, MD, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206554PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6211695PMC
April 2019

Investigation of the formation of drug-drug cocrystals and coamorphous systems of the antidiabetic drug gliclazide.

Int J Pharm 2019 Apr 23;561:35-42. Epub 2019 Feb 23.

Synthesis & Solid State Pharmaceutical Centre (SSPC) and School of Chemistry, National University of Ireland, Galway, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03785173193014
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http://dx.doi.org/10.1016/j.ijpharm.2019.02.024DOI Listing
April 2019

Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting.

Authors:
Ganesh Chauhan Hieab H H Adams Claudia L Satizabal Joshua C Bis Alexander Teumer Muralidharan Sargurupremraj Edith Hofer Stella Trompet Saima Hilal Albert Vernon Smith Xueqiu Jian Rainer Malik Matthew Traylor Sara L Pulit Philippe Amouyel Bernard Mazoyer Yi-Cheng Zhu Sara Kaffashian Sabrina Schilling Gary W Beecham Thomas J Montine Gerard D Schellenberg Olafur Kjartansson Vilmundur Guðnason David S Knopman Michael E Griswold B Gwen Windham Rebecca F Gottesman Thomas H Mosley Reinhold Schmidt Yasaman Saba Helena Schmidt Fumihiko Takeuchi Shuhei Yamaguchi Toru Nabika Norihiro Kato Kumar B Rajan Neelum T Aggarwal Philip L De Jager Denis A Evans Bruce M Psaty Jerome I Rotter Kenneth Rice Oscar L Lopez Jiemin Liao Christopher Chen Ching-Yu Cheng Tien Y Wong Mohammad K Ikram Sven J van der Lee Najaf Amin Vincent Chouraki Anita L DeStefano Hugo J Aparicio Jose R Romero Pauline Maillard Charles DeCarli Joanna M Wardlaw Maria Del C Valdés Hernández Michelle Luciano David Liewald Ian J Deary John M Starr Mark E Bastin Susana Muñoz Maniega P Eline Slagboom Marian Beekman Joris Deelen Hae-Won Uh Robin Lemmens Henry Brodaty Margaret J Wright David Ames Giorgio B Boncoraglio Jemma C Hopewell Ashley H Beecham Susan H Blanton Clinton B Wright Ralph L Sacco Wei Wen Anbupalam Thalamuthu Nicola J Armstrong Elizabeth Chong Peter R Schofield John B Kwok Jeroen van der Grond David J Stott Ian Ford J Wouter Jukema Meike W Vernooij Albert Hofman André G Uitterlinden Aad van der Lugt Katharina Wittfeld Hans J Grabe Norbert Hosten Bettina von Sarnowski Uwe Völker Christopher Levi Jordi Jimenez-Conde Pankaj Sharma Cathie L M Sudlow Jonathan Rosand Daniel Woo John W Cole James F Meschia Agnieszka Slowik Vincent Thijs Arne Lindgren Olle Melander Raji P Grewal Tatjana Rundek Kathy Rexrode Peter M Rothwell Donna K Arnett Christina Jern Julie A Johnson Oscar R Benavente Sylvia Wasssertheil-Smoller Jin-Moo Lee Quenna Wong Braxton D Mitchell Stephen S Rich Patrick F McArdle Mirjam I Geerlings Yolanda van der Graaf Paul I W de Bakker Folkert W Asselbergs Velandai Srikanth Russell Thomson Rebekah McWhirter Chris Moran Michele Callisaya Thanh Phan Loes C A Rutten-Jacobs Steve Bevan Christophe Tzourio Karen A Mather Perminder S Sachdev Cornelia M van Duijn Bradford B Worrall Martin Dichgans Steven J Kittner Hugh S Markus Mohammad A Ikram Myriam Fornage Lenore J Launer Sudha Seshadri W T Longstreth Stéphanie Debette

Neurology 2019 Jan 16. Epub 2019 Jan 16.

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http://dx.doi.org/10.1212/WNL.0000000000006851DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6369905PMC
January 2019

Atrial fibrillation genetic risk differentiates cardioembolic stroke from other stroke subtypes.

Neurol Genet 2018 Dec 3;4(6):e293. Epub 2018 Dec 3.

Department of Genetics (S.L.P., P.I.W.d. B.), University Medical Center Utrecht, Utrecht University, The Netherlands; P.I.W.d.B. is now with Computational Genomics, Vertex Pharmaceuticals, Boston, MA; Li Ka Shing Centre for Health Information and Discovery (S.L.P.), The Big Data Institute, University of Oxford, United Kingdom; Program in Medical and Population Genetics (S.L.P., L.-C.W., S.H.C., J.R., P.T.E., S.A.L., C.D.A.), Broad Institute, Cambridge, MA; Cardiovascular Research Center (L.-C.W., P.T.E., S.A.L.), Center for Genomic Medicine (J.R., C.D.A.), J.P. Kistler Stroke Research Center (J.R., C.D.A.), and Cardiac Arrhythmia Service (P.T.E., S.A.L.), Massachusetts General Hospital, Boston; Department of Medicine (P.F.M., B.D.M.), Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore; National Heart, Lung, and Blood Institute's and Boston University's Framingham Heart Study (L.T., E.J.B.); Department of Biostatistics (L.T.) and Department of Epidemiology (E.J.B.), Boston University School of Public Health, MA; Geriatrics Research and Education Clinical Center (B.D.M.), Baltimore Veterans Administration Medical Center, MD; Cardiology Preventive Medicine Sections (E.J.B.), Evans Department of Medicine, Boston University School of Medicine; Department of Neurology (S.J.K.), University of Maryland School of Medicine; and Department of Neurology (S.J.K.), Veterans Affairs Medical Center, Baltimore, MD.

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http://dx.doi.org/10.1212/NXG.0000000000000293DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6283455PMC
December 2018

One-Pot Synthesis of Dihalogenated Ring-Fused Benzimidazolequinones from 3,6-Dimethoxy-2-(cycloamino)anilines Using Hydrogen Peroxide and Hydrohalic Acid.

Org Lett 2018 11 22;20(21):6970-6974. Epub 2018 Oct 22.

School of Chemistry , National University of Ireland Galway , University Road, Galway , H91 TK33 , Ireland.

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http://dx.doi.org/10.1021/acs.orglett.8b03135DOI Listing
November 2018

An innovative and efficient route to the synthesis of metal-based glycoconjugates: proof-of-concept and potential applications.

Dalton Trans 2018 Aug 26;47(31):10721-10736. Epub 2018 Jun 26.

National University of Ireland Galway, School of Chemistry, University Road, H91 TK33 Galway, Co., Galway, Ireland.

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http://dx.doi.org/10.1039/c8dt01583jDOI Listing
August 2018

Synthesis of N-[(dialkylamino)methyl]acrylamides and N-[(dialkylamino)methyl]methacrylamides from Schiff base salts: useful building blocks for smart polymers.

Org Biomol Chem 2018 06;16(22):4108-4116

School of Chemistry, National University of Ireland Galway, University Road, Galway, Ireland.

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http://dx.doi.org/10.1039/c8ob00811fDOI Listing
June 2018

Selective Methylmagnesium Chloride Mediated Acetylations of Isosorbide: A Route to Powerful Nitric Oxide Donor Furoxans.

Org Lett 2018 05 26;20(10):3025-3029. Epub 2018 Apr 26.

School of Chemistry , National University of Ireland Galway , University Road , Galway , H91 TK33 , Ireland.

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http://dx.doi.org/10.1021/acs.orglett.8b01060DOI Listing
May 2018

Synthesis of pyrazolopyrimidinones using a "one-pot" approach under microwave irradiation.

Beilstein J Org Chem 2018 28;14:1222-1228. Epub 2018 May 28.

Department of Chemistry, Maynooth University, Maynooth, Co. Kildare, Ireland.

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http://dx.doi.org/10.3762/bjoc.14.104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6009099PMC
May 2018

Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.

Authors:
Rainer Malik Ganesh Chauhan Matthew Traylor Muralidharan Sargurupremraj Yukinori Okada Aniket Mishra Loes Rutten-Jacobs Anne-Katrin Giese Sander W van der Laan Solveig Gretarsdottir Christopher D Anderson Michael Chong Hieab H H Adams Tetsuro Ago Peter Almgren Philippe Amouyel Hakan Ay Traci M Bartz Oscar R Benavente Steve Bevan Giorgio B Boncoraglio Robert D Brown Adam S Butterworth Caty Carrera Cara L Carty Daniel I Chasman Wei-Min Chen John W Cole Adolfo Correa Ioana Cotlarciuc Carlos Cruchaga John Danesh Paul I W de Bakker Anita L DeStefano Marcel den Hoed Qing Duan Stefan T Engelter Guido J Falcone Rebecca F Gottesman Raji P Grewal Vilmundur Gudnason Stefan Gustafsson Jeffrey Haessler Tamara B Harris Ahamad Hassan Aki S Havulinna Susan R Heckbert Elizabeth G Holliday George Howard Fang-Chi Hsu Hyacinth I Hyacinth M Arfan Ikram Erik Ingelsson Marguerite R Irvin Xueqiu Jian Jordi Jiménez-Conde Julie A Johnson J Wouter Jukema Masahiro Kanai Keith L Keene Brett M Kissela Dawn O Kleindorfer Charles Kooperberg Michiaki Kubo Leslie A Lange Carl D Langefeld Claudia Langenberg Lenore J Launer Jin-Moo Lee Robin Lemmens Didier Leys Cathryn M Lewis Wei-Yu Lin Arne G Lindgren Erik Lorentzen Patrik K Magnusson Jane Maguire Ani Manichaikul Patrick F McArdle James F Meschia Braxton D Mitchell Thomas H Mosley Michael A Nalls Toshiharu Ninomiya Martin J O'Donnell Bruce M Psaty Sara L Pulit Kristiina Rannikmäe Alexander P Reiner Kathryn M Rexrode Kenneth Rice Stephen S Rich Paul M Ridker Natalia S Rost Peter M Rothwell Jerome I Rotter Tatjana Rundek Ralph L Sacco Saori Sakaue Michele M Sale Veikko Salomaa Bishwa R Sapkota Reinhold Schmidt Carsten O Schmidt Ulf Schminke Pankaj Sharma Agnieszka Slowik Cathie L M Sudlow Christian Tanislav Turgut Tatlisumak Kent D Taylor Vincent N S Thijs Gudmar Thorleifsson Unnur Thorsteinsdottir Steffen Tiedt Stella Trompet Christophe Tzourio Cornelia M van Duijn Matthew Walters Nicholas J Wareham Sylvia Wassertheil-Smoller James G Wilson Kerri L Wiggins Qiong Yang Salim Yusuf Joshua C Bis Tomi Pastinen Arno Ruusalepp Eric E Schadt Simon Koplev Johan L M Björkegren Veronica Codoni Mete Civelek Nicholas L Smith David A Trégouët Ingrid E Christophersen Carolina Roselli Steven A Lubitz Patrick T Ellinor E Shyong Tai Jaspal S Kooner Norihiro Kato Jiang He Pim van der Harst Paul Elliott John C Chambers Fumihiko Takeuchi Andrew D Johnson Dharambir K Sanghera Olle Melander Christina Jern Daniel Strbian Israel Fernandez-Cadenas W T Longstreth Arndt Rolfs Jun Hata Daniel Woo Jonathan Rosand Guillaume Pare Jemma C Hopewell Danish Saleheen Kari Stefansson Bradford B Worrall Steven J Kittner Sudha Seshadri Myriam Fornage Hugh S Markus Joanna M M Howson Yoichiro Kamatani Stephanie Debette Martin Dichgans

Nat Genet 2018 04 12;50(4):524-537. Epub 2018 Mar 12.

Institute for Stroke and Dementia Research (ISD), University Hospital, LMU Munich, Munich, Germany.

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http://dx.doi.org/10.1038/s41588-018-0058-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968830PMC
April 2018

The natural bile acid surfactant sodium taurocholate (NaTC) as a coformer in coamorphous systems: Enhanced physical stability and dissolution behavior of coamorphous drug-NaTc systems.

Int J Pharm 2018 Jan 28;535(1-2):132-139. Epub 2017 Oct 28.

School of Chemistry, National University of Ireland, Galway, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2017.10.049DOI Listing
January 2018

The CAPN2/CAPN8 Locus on Chromosome 1q Is Associated with Variation in Serum Alpha-Carotene Concentrations.

J Nutrigenet Nutrigenomics 2016 22;9(5-6):254-264. Epub 2016 Dec 22.

Department of Family & Community Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1159/000452890DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5535757PMC
November 2017

Stereoselective Epimerizations of Glycosyl Thiols.

Org Lett 2017 11;19(21):5802-5805

School of Chemistry, National University of Ireland Galway , University Road, Galway, Ireland H91 TK33.

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http://pubs.acs.org/doi/abs/10.1021/acs.orglett.7b02760
Publisher Site
http://dx.doi.org/10.1021/acs.orglett.7b02760DOI Listing
November 2017

A comprehensive spectroscopic study of the polymorphs of diflunisal and their phase transformations.

Int J Pharm 2017 Aug 8;528(1-2):312-321. Epub 2017 Jun 8.

School of Chemistry, National University of Ireland, Galway, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.ijpharm.2017.06.020DOI Listing
August 2017

Quantitative assessment of copper proteinates used as animal feed additives using ATR-FTIR spectroscopy and powder X-ray diffraction (PXRD) analysis.

Food Addit Contam Part A Chem Anal Control Expo Risk Assess 2017 Aug 11;34(8):1344-1352. Epub 2017 Jul 11.

a Alltech European Bioscience Centre , Dunboyne, Co . Meath , Ireland.

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http://dx.doi.org/10.1080/19440049.2017.1342144DOI Listing
August 2017

Synthesis and crystal structures of cobalt(II), cadmium(II), and zinc(II) complexes of 4-nitro phenylcyanamide: enhancing the biological properties through bound to human serum albumin.

J Biomol Struct Dyn 2017 Jul 16;35(9):2055-2065. Epub 2016 Aug 16.

b School of Chemistry , National University of Ireland Galway , University Road, Galway , Ireland.

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http://dx.doi.org/10.1080/07391102.2016.1201006DOI Listing
July 2017

Sex-specific effects of serum sulfate level and nonsense variants on DHEA homeostasis.

Mol Genet Metab Rep 2017 Mar 27;10:84-91. Epub 2017 Jan 27.

Program for Personalized and Genomic Medicine and Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, MD, United States.

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http://dx.doi.org/10.1016/j.ymgmr.2017.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278115PMC
March 2017

Genome-wide analysis identifies 12 loci influencing human reproductive behavior.

Authors:
Nicola Barban Rick Jansen Ronald de Vlaming Ahmad Vaez Jornt J Mandemakers Felix C Tropf Xia Shen James F Wilson Daniel I Chasman Ilja M Nolte Vinicius Tragante Sander W van der Laan John R B Perry Augustine Kong Tarunveer S Ahluwalia Eva Albrecht Laura Yerges-Armstrong Gil Atzmon Kirsi Auro Kristin Ayers Andrew Bakshi Danny Ben-Avraham Klaus Berger Aviv Bergman Lars Bertram Lawrence F Bielak Gyda Bjornsdottir Marc Jan Bonder Linda Broer Minh Bui Caterina Barbieri Alana Cavadino Jorge E Chavarro Constance Turman Maria Pina Concas Heather J Cordell Gail Davies Peter Eibich Nicholas Eriksson Tõnu Esko Joel Eriksson Fahimeh Falahi Janine F Felix Mark Alan Fontana Lude Franke Ilaria Gandin Audrey J Gaskins Christian Gieger Erica P Gunderson Xiuqing Guo Caroline Hayward Chunyan He Edith Hofer Hongyan Huang Peter K Joshi Stavroula Kanoni Robert Karlsson Stefan Kiechl Annette Kifley Alexander Kluttig Peter Kraft Vasiliki Lagou Cecile Lecoeur Jari Lahti Ruifang Li-Gao Penelope A Lind Tian Liu Enes Makalic Crysovalanto Mamasoula Lindsay Matteson Hamdi Mbarek Patrick F McArdle George McMahon S Fleur W Meddens Evelin Mihailov Mike Miller Stacey A Missmer Claire Monnereau Peter J van der Most Ronny Myhre Mike A Nalls Teresa Nutile Ioanna Panagiota Kalafati Eleonora Porcu Inga Prokopenko Kumar B Rajan Janet Rich-Edwards Cornelius A Rietveld Antonietta Robino Lynda M Rose Rico Rueedi Kathleen A Ryan Yasaman Saba Daniel Schmidt Jennifer A Smith Lisette Stolk Elizabeth Streeten Anke Tönjes Gudmar Thorleifsson Sheila Ulivi Juho Wedenoja Juergen Wellmann Peter Willeit Jie Yao Loic Yengo Jing Hua Zhao Wei Zhao Daria V Zhernakova Najaf Amin Howard Andrews Beverley Balkau Nir Barzilai Sven Bergmann Ginevra Biino Hans Bisgaard Klaus Bønnelykke Dorret I Boomsma Julie E Buring Harry Campbell Stefania Cappellani Marina Ciullo Simon R Cox Francesco Cucca Daniela Toniolo George Davey-Smith Ian J Deary George Dedoussis Panos Deloukas Cornelia M van Duijn Eco J C de Geus Johan G Eriksson Denis A Evans Jessica D Faul Cinzia Felicita Sala Philippe Froguel Paolo Gasparini Giorgia Girotto Hans-Jörgen Grabe Karin Halina Greiser Patrick J F Groenen Hugoline G de Haan Johannes Haerting Tamara B Harris Andrew C Heath Kauko Heikkilä Albert Hofman Georg Homuth Elizabeth G Holliday John Hopper Elina Hyppönen Bo Jacobsson Vincent W V Jaddoe Magnus Johannesson Astanand Jugessur Mika Kähönen Eero Kajantie Sharon L R Kardia Bernard Keavney Ivana Kolcic Päivikki Koponen Peter Kovacs Florian Kronenberg Zoltan Kutalik Martina La Bianca Genevieve Lachance William G Iacono Sandra Lai Terho Lehtimäki David C Liewald Cecilia M Lindgren Yongmei Liu Robert Luben Michael Lucht Riitta Luoto Per Magnus Patrik K E Magnusson Nicholas G Martin Matt McGue Ruth McQuillan Sarah E Medland Christa Meisinger Dan Mellström Andres Metspalu Michela Traglia Lili Milani Paul Mitchell Grant W Montgomery Dennis Mook-Kanamori Renée de Mutsert Ellen A Nohr Claes Ohlsson Jørn Olsen Ken K Ong Lavinia Paternoster Alison Pattie Brenda W J H Penninx Markus Perola Patricia A Peyser Mario Pirastu Ozren Polasek Chris Power Jaakko Kaprio Leslie J Raffel Katri Räikkönen Olli Raitakari Paul M Ridker Susan M Ring Kathryn Roll Igor Rudan Daniela Ruggiero Dan Rujescu Veikko Salomaa David Schlessinger Helena Schmidt Reinhold Schmidt Nicole Schupf Johannes Smit Rossella Sorice Tim D Spector John M Starr Doris Stöckl Konstantin Strauch Michael Stumvoll Morris A Swertz Unnur Thorsteinsdottir A Roy Thurik Nicholas J Timpson Joyce Y Tung André G Uitterlinden Simona Vaccargiu Jorma Viikari Veronique Vitart Henry Völzke Peter Vollenweider Dragana Vuckovic Johannes Waage Gert G Wagner Jie Jin Wang Nicholas J Wareham David R Weir Gonneke Willemsen Johann Willeit Alan F Wright Krina T Zondervan Kari Stefansson Robert F Krueger James J Lee Daniel J Benjamin David Cesarini Philipp D Koellinger Marcel den Hoed Harold Snieder Melinda C Mills

Nat Genet 2016 12 31;48(12):1462-1472. Epub 2016 Oct 31.

Department of Sociology and Nuffield College, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3698DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5695684PMC
December 2016

The Next Step Forward Is to Take a Step Back.

Diabetes 2016 10;65(10):2824-5

Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, and Program in Epidemiology and Human Genetics, University of Maryland School of Medicine, Baltimore, MD

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http://dx.doi.org/10.2337/dbi16-0044DOI Listing
October 2016

Spice MyPlate: Nutrition Education Focusing Upon Spices and Herbs Improved Diet Quality and Attitudes Among Urban High School Students.

Am J Health Promot 2016 05;30(5):346-56

The Department of Family and Community Medicine, and Center for Integrative Medicine, University of Maryland, Baltimore, MD, USA.

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http://dx.doi.org/10.1177/0890117116646333DOI Listing
May 2016

Collider-stratification Bias Due to Censoring in Prospective Cohort Studies.

Epidemiology 2016 Mar;27(2):e4-5

Department of Biostatistics and Epidemiology, University of Massachusetts, Amherst, MA, Division of Endocrinology, Diabetes, and Nutrition, University of Maryland, School of Medicine, Baltimore, MD.

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http://dx.doi.org/10.1097/EDE.0000000000000432DOI Listing
March 2016

Design of Lead(II) Metal-Organic Frameworks Based on Covalent and Tetrel Bonding.

Chemistry 2015 Dec 22;21(49):17951-8. Epub 2015 Oct 22.

Department of Chemistry, Faculty of Science, University of Maragheh, P.O. Box 55181-83111, Maragheh (Iran).

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http://dx.doi.org/10.1002/chem.201501916DOI Listing
December 2015

Allylic Azide Rearrangement in Tandem with Huisgen Cycloaddition for Stereoselective Annulation: Synthesis of C-Glycosyl Iminosugars.

Org Lett 2015 Dec 9;17(24):6226-9. Epub 2015 Dec 9.

School of Chemistry, National University of Ireland Galway , University Road, Galway, Ireland.

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http://dx.doi.org/10.1021/acs.orglett.5b03209DOI Listing
December 2015

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Authors:
Felix R Day Katherine S Ruth Deborah J Thompson Kathryn L Lunetta Natalia Pervjakova Daniel I Chasman Lisette Stolk Hilary K Finucane Patrick Sulem Brendan Bulik-Sullivan Tõnu Esko Andrew D Johnson Cathy E Elks Nora Franceschini Chunyan He Elisabeth Altmaier Jennifer A Brody Lude L Franke Jennifer E Huffman Margaux F Keller Patrick F McArdle Teresa Nutile Eleonora Porcu Antonietta Robino Lynda M Rose Ursula M Schick Jennifer A Smith Alexander Teumer Michela Traglia Dragana Vuckovic Jie Yao Wei Zhao Eva Albrecht Najaf Amin Tanguy Corre Jouke-Jan Hottenga Massimo Mangino Albert V Smith Toshiko Tanaka Goncalo Abecasis Irene L Andrulis Hoda Anton-Culver Antonis C Antoniou Volker Arndt Alice M Arnold Caterina Barbieri Matthias W Beckmann Alicia Beeghly-Fadiel Javier Benitez Leslie Bernstein Suzette J Bielinski Carl Blomqvist Eric Boerwinkle Natalia V Bogdanova Stig E Bojesen Manjeet K Bolla Anne-Lise Borresen-Dale Thibaud S Boutin Hiltrud Brauch Hermann Brenner Thomas Brüning Barbara Burwinkel Archie Campbell Harry Campbell Stephen J Chanock J Ross Chapman Yii-Der Ida Chen Georgia Chenevix-Trench Fergus J Couch Andrea D Coviello Angela Cox Kamila Czene Hatef Darabi Immaculata De Vivo Ellen W Demerath Joe Dennis Peter Devilee Thilo Dörk Isabel Dos-Santos-Silva Alison M Dunning John D Eicher Peter A Fasching Jessica D Faul Jonine Figueroa Dieter Flesch-Janys Ilaria Gandin Melissa E Garcia Montserrat García-Closas Graham G Giles Giorgia G Girotto Mark S Goldberg Anna González-Neira Mark O Goodarzi Megan L Grove Daniel F Gudbjartsson Pascal Guénel Xiuqing Guo Christopher A Haiman Per Hall Ute Hamann Brian E Henderson Lynne J Hocking Albert Hofman Georg Homuth Maartje J Hooning John L Hopper Frank B Hu Jinyan Huang Keith Humphreys David J Hunter Anna Jakubowska Samuel E Jones Maria Kabisch David Karasik Julia A Knight Ivana Kolcic Charles Kooperberg Veli-Matti Kosma Jennifer Kriebel Vessela Kristensen Diether Lambrechts Claudia Langenberg Jingmei Li Xin Li Sara Lindström Yongmei Liu Jian'an Luan Jan Lubinski Reedik Mägi Arto Mannermaa Judith Manz Sara Margolin Jonathan Marten Nicholas G Martin Corrado Masciullo Alfons Meindl Kyriaki Michailidou Evelin Mihailov Lili Milani Roger L Milne Martina Müller-Nurasyid Michael Nalls Ben M Neale Heli Nevanlinna Patrick Neven Anne B Newman Børge G Nordestgaard Janet E Olson Sandosh Padmanabhan Paolo Peterlongo Ulrike Peters Astrid Petersmann Julian Peto Paul D P Pharoah Nicola N Pirastu Ailith Pirie Giorgio Pistis Ozren Polasek David Porteous Bruce M Psaty Katri Pylkäs Paolo Radice Leslie J Raffel Fernando Rivadeneira Igor Rudan Anja Rudolph Daniela Ruggiero Cinzia F Sala Serena Sanna Elinor J Sawyer David Schlessinger Marjanka K Schmidt Frank Schmidt Rita K Schmutzler Minouk J Schoemaker Robert A Scott Caroline M Seynaeve Jacques Simard Rossella Sorice Melissa C Southey Doris Stöckl Konstantin Strauch Anthony Swerdlow Kent D Taylor Unnur Thorsteinsdottir Amanda E Toland Ian Tomlinson Thérèse Truong Laufey Tryggvadottir Stephen T Turner Diego Vozzi Qin Wang Melissa Wellons Gonneke Willemsen James F Wilson Robert Winqvist Bruce B H R Wolffenbuttel Alan F Wright Drakoulis Yannoukakos Tatijana Zemunik Wei Zheng Marek Zygmunt Sven Bergmann Dorret I Boomsma Julie E Buring Luigi Ferrucci Grant W Montgomery Vilmundur Gudnason Tim D Spector Cornelia M van Duijn Behrooz Z Alizadeh Marina Ciullo Laura Crisponi Douglas F Easton Paolo P Gasparini Christian Gieger Tamara B Harris Caroline Hayward Sharon L R Kardia Peter Kraft Barbara McKnight Andres Metspalu Alanna C Morrison Alex P Reiner Paul M Ridker Jerome I Rotter Daniela Toniolo André G Uitterlinden Sheila Ulivi Henry Völzke Nicholas J Wareham David R Weir Laura M Yerges-Armstrong Alkes L Price Kari Stefansson Jenny A Visser Ken K Ong Jenny Chang-Claude Joanne M Murabito John R B Perry Anna Murray

Nat Genet 2015 Nov 28;47(11):1294-1303. Epub 2015 Sep 28.

Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, EX2 5DW, UK.

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http://dx.doi.org/10.1038/ng.3412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4661791PMC
November 2015

An aid to generating figures for the American Journal of Epidemiology using SAS/GRAPH.

Am J Epidemiol 2015 Nov 16;182(9):747-9. Epub 2015 Oct 16.

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http://dx.doi.org/10.1093/aje/kwv216DOI Listing
November 2015

Nickel(II) and cobalt(II) complexes of lidocaine: Synthesis, structure and comparative in vitro evaluations of biological perspectives.

Eur J Med Chem 2015 Oct 15;103:516-29. Epub 2015 Sep 15.

Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran.

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http://dx.doi.org/10.1016/j.ejmech.2015.09.018DOI Listing
October 2015

Synthesis of a Spirocyclic Oxetane-Fused Benzimidazole.

Molecules 2015 Jul 30;20(8):13864-74. Epub 2015 Jul 30.

School of Chemistry, National University of Ireland Galway, University Road, Galway SW4 NUI, Ireland.

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http://dx.doi.org/10.3390/molecules200813864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332447PMC
July 2015

Obesity increases risk of ischemic stroke in young adults.

Stroke 2015 Jun 5;46(6):1690-2. Epub 2015 May 5.

From the Departments of Neurology (A.B.M., J.W.C., M.J.S., S.J.K.) and Medicine (P.F.M., Y.-C.C., K.A.R., B.D.M.), University of Maryland School of Medicine, Baltimore; and Department of Veterans Affairs and Veterans Affairs Medical Center Baltimore, MD (J.W.C., Y.-C.C., S.J.K.).

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http://dx.doi.org/10.1161/STROKEAHA.115.008940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458137PMC
June 2015

One-pot hydrogen peroxide and hydrohalic acid induced ring closure and selective aromatic halogenation to give new ring-fused benzimidazoles.

Org Lett 2015 Jun 19;17(11):2856-9. Epub 2015 May 19.

School of Chemistry, National University of Ireland Galway, University Road, Galway, Ireland.

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http://dx.doi.org/10.1021/acs.orglett.5b01317DOI Listing
June 2015

A novel one-dimensional manganese(II) coordination polymer containing both dicyanamide and pyrazinamide ligands: synthesis, spectroscopic investigations, X-ray studies and evaluation of biological activities.

Spectrochim Acta A Mol Biomol Spectrosc 2015 Mar 25;139:307-12. Epub 2014 Dec 25.

School of Chemistry, National University of Ireland Galway, University Road, Galway, Ireland.

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http://dx.doi.org/10.1016/j.saa.2014.12.072DOI Listing
March 2015

Synthesis, crystal structure and spectroscopy of bioactive Cd(II) polymeric complex of the non-steroidal anti-inflammatory drug diclofenac sodium: antiproliferative and biological activity.

Spectrochim Acta A Mol Biomol Spectrosc 2015 Feb 28;136 Pt B:429-36. Epub 2014 Sep 28.

School of Chemistry, National University of Ireland Galway, University Road, Galway, Ireland.

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http://dx.doi.org/10.1016/j.saa.2014.09.053DOI Listing
February 2015

Pathogenic ischemic stroke phenotypes in the NINDS-stroke genetics network.

Stroke 2014 Dec 6;45(12):3589-96. Epub 2014 Nov 6.

From the Department of Radiology, AA Martinos Center for Biomedical Imaging (H.A., E.M.A., T.B.), Stroke Service, Department of Neurology (H.A., J.R.), and Center for Human Genetic Research (J.R.), Massachusetts General Hospital, Harvard Medical School, Boston; Department of Neurology and Rehabilitation Medicine, Skåne University Hospital, Lund, Sweden (G.A., H.D., A.L., O.M., B.N.); Department of Neurology, Mayo Clinic Rochester, MN (R.D.B.); Department of Neurology (S.N.C., B.B.W.), Center for Public Health Genomics (S.S.R.), and Department of Public Health Sciences (B.B.W.), University of Virginia, Charlottesville; Department of Neurology (J.W.C., S.J.K.) and Division of Endocrinology, Diabetes, and Nutrition, Department of Medicine (P.F.M.), University of Maryland School of Medicine, Baltimore; Institute for Stroke and Dementia Research (ISD), Klinikum der Universität München, Ludwig-Maximilians-University, München, Germany (M.D., M.L.); Department of Clinical Science, Lund University, Malmö, Sweden (G.E., B.N.); Department of Neurology, Neurovascular Research Group, IMIM-Hospital del Mar, Universitat Autonoma de Barcelona/DCEXS-Universitat Pompeu Fabra, Spain (E.G.-S., J.J.-C., J.R.); Neuroscience Institute, Saint Francis Medical Center, Trenton, NJ (R.P.G., L.R.P.); National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (K.G.); Institute of Biomedicine (C.J., A.P.) and Institute of Neuroscience and Physiology (K.J.), Sahlgrenska Academy at University of Gothenburg, Sweden; Department of Neurology, University of Miami Miller School of Medicine, FL (M.K., T.R., R.L.S.); Department of Neurology, University of Cincinnati College of Medicine, OH (B.K., D.O.K.); Department of Neurology, Stern Stroke Center, Albert Einstein College of Medicine, Bronx, NY (D.L.L.); Department of Neuroscience and Sensory Organs, Policlinico Hospital Foundation IRCCS Cà Granda, Milan, Italy (S.L.); Department of Neurology, Washington U

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http://dx.doi.org/10.1161/STROKEAHA.114.007362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4286169PMC
December 2014

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

Authors:
John Rb Perry Felix Day Cathy E Elks Patrick Sulem Deborah J Thompson Teresa Ferreira Chunyan He Daniel I Chasman Tõnu Esko Gudmar Thorleifsson Eva Albrecht Wei Q Ang Tanguy Corre Diana L Cousminer Bjarke Feenstra Nora Franceschini Andrea Ganna Andrew D Johnson Sanela Kjellqvist Kathryn L Lunetta George McMahon Ilja M Nolte Lavinia Paternoster Eleonora Porcu Albert V Smith Lisette Stolk Alexander Teumer Natalia Tšernikova Emmi Tikkanen Sheila Ulivi Erin K Wagner Najaf Amin Laura J Bierut Enda M Byrne Jouke-Jan Hottenga Daniel L Koller Massimo Mangino Tune H Pers Laura M Yerges-Armstrong Jing Hua Zhao Irene L Andrulis Hoda Anton-Culver Femke Atsma Stefania Bandinelli Matthias W Beckmann Javier Benitez Carl Blomqvist Stig E Bojesen Manjeet K Bolla Bernardo Bonanni Hiltrud Brauch Hermann Brenner Julie E Buring Jenny Chang-Claude Stephen Chanock Jinhui Chen Georgia Chenevix-Trench J Margriet Collée Fergus J Couch David Couper Andrea D Coveillo Angela Cox Kamila Czene Adamo Pio D'adamo George Davey Smith Immaculata De Vivo Ellen W Demerath Joe Dennis Peter Devilee Aida K Dieffenbach Alison M Dunning Gudny Eiriksdottir Johan G Eriksson Peter A Fasching Luigi Ferrucci Dieter Flesch-Janys Henrik Flyger Tatiana Foroud Lude Franke Melissa E Garcia Montserrat García-Closas Frank Geller Eco Ej de Geus Graham G Giles Daniel F Gudbjartsson Vilmundur Gudnason Pascal Guénel Suiqun Guo Per Hall Ute Hamann Robin Haring Catharina A Hartman Andrew C Heath Albert Hofman Maartje J Hooning John L Hopper Frank B Hu David J Hunter David Karasik Douglas P Kiel Julia A Knight Veli-Matti Kosma Zoltan Kutalik Sandra Lai Diether Lambrechts Annika Lindblom Reedik Mägi Patrik K Magnusson Arto Mannermaa Nicholas G Martin Gisli Masson Patrick F McArdle Wendy L McArdle Mads Melbye Kyriaki Michailidou Evelin Mihailov Lili Milani Roger L Milne Heli Nevanlinna Patrick Neven Ellen A Nohr Albertine J Oldehinkel Ben A Oostra Aarno Palotie Munro Peacock Nancy L Pedersen Paolo Peterlongo Julian Peto Paul Dp Pharoah Dirkje S Postma Anneli Pouta Katri Pylkäs Paolo Radice Susan Ring Fernando Rivadeneira Antonietta Robino Lynda M Rose Anja Rudolph Veikko Salomaa Serena Sanna David Schlessinger Marjanka K Schmidt Mellissa C Southey Ulla Sovio Meir J Stampfer Doris Stöckl Anna M Storniolo Nicholas J Timpson Jonathan Tyrer Jenny A Visser Peter Vollenweider Henry Völzke Gerard Waeber Melanie Waldenberger Henri Wallaschofski Qin Wang Gonneke Willemsen Robert Winqvist Bruce Hr Wolffenbuttel Margaret J Wright Dorret I Boomsma Michael J Econs Kay-Tee Khaw Ruth Jf Loos Mark I McCarthy Grant W Montgomery John P Rice Elizabeth A Streeten Unnur Thorsteinsdottir Cornelia M van Duijn Behrooz Z Alizadeh Sven Bergmann Eric Boerwinkle Heather A Boyd Laura Crisponi Paolo Gasparini Christian Gieger Tamara B Harris Erik Ingelsson Marjo-Riitta Järvelin Peter Kraft Debbie Lawlor Andres Metspalu Craig E Pennell Paul M Ridker Harold Snieder Thorkild Ia Sørensen Tim D Spector David P Strachan André G Uitterlinden Nicholas J Wareham Elisabeth Widen Marek Zygmunt Anna Murray Douglas F Easton Kari Stefansson Joanne M Murabito Ken K Ong

Nature 2014 Oct 23;514(7520):92-97. Epub 2014 Jul 23.

MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Box 285 Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.1038/nature13545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185210PMC
October 2014

Photochemical aryl radical cyclizations to give (E)-3-ylideneoxindoles.

Molecules 2014 Sep 30;19(10):15891-9. Epub 2014 Sep 30.

School of Chemistry, National University of Ireland Galway, University Road, Galway, Ireland.

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http://dx.doi.org/10.3390/molecules191015891DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6270804PMC
September 2014

Effects of ball-milling and cryomilling on sulfamerazine polymorphs: a quantitative study.

J Pharm Sci 2014 Jun 22;103(6):1766-78. Epub 2014 Apr 22.

School of Chemistry, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1002/jps.23978DOI Listing
June 2014

Tandem reactions via Barton esters with intermolecular addition and vinyl radical substitution onto indole.

J Org Chem 2014 Jun 28;79(12):5903-7. Epub 2014 May 28.

School of Chemistry, National University of Ireland Galway , University Road, Galway, Ireland.

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http://dx.doi.org/10.1021/jo5008543DOI Listing
June 2014

Prothrombin G20210A mutation is associated with young-onset stroke: the genetics of early-onset stroke study and meta-analysis.

Stroke 2014 Apr 11;45(4):961-7. Epub 2014 Mar 11.

From the Departments of Neurology (B.J., A.H., M.J.S., M.A.W., B.J.S., S.J.K., J.W.C.), Medicine (K.A.R., Y.C., P.F.M., J.R.O., B.D.M.), and Epidemiology and Public Health (O.C.S.), University of Maryland School of Medicine, Baltimore; Centers for Disease Control and Prevention, Atlanta, GA (D.K., C.J.B., M.G., W.C.H.); Department of Veterans Affairs, Veterans Affairs Medical Center Baltimore, MD (Y.C., M.A.W., B.J.S., S.J.K., J.W.C.); and Department of Veterans Affairs and Veterans Affairs Medical Center Baltimore, Geriatric Research, Education and Clinical Center, MD (B.D.M., S.J.K.).

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http://dx.doi.org/10.1161/STROKEAHA.113.004063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049002PMC
April 2014

Prevention opportunities for oral contraceptive-associated ischemic stroke.

Stroke 2014 Mar 21;45(3):893-5. Epub 2014 Jan 21.

From the Departments of Medicine (K.A.R., B.D.M., P.F.M., Y.-C.C.) and Neurology (J.W.C., K.S., M.J.S., S.J.K.), University of Maryland School of Medicine, Baltimore, MD; and Medical Research Service, Veteran Affairs Medical Center, Baltimore, MD (J.W.C., B.D.M., M.J.S., Y.-C.C., S.J.K.).

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http://dx.doi.org/10.1161/STROKEAHA.113.004023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010181PMC
March 2014

Analysis of the bereavement effect after the death of a spouse in the Amish: a population-based retrospective cohort study.

BMJ Open 2014 Jan 15;4(1):e003670. Epub 2014 Jan 15.

Department of Medicine and Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2013-00367
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http://dx.doi.org/10.1136/bmjopen-2013-003670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3902313PMC
January 2014

Stroke Genetics Network (SiGN) study: design and rationale for a genome-wide association study of ischemic stroke subtypes.

Stroke 2013 Oct 10;44(10):2694-702. Epub 2013 Sep 10.

From the Mayo Clinic Jacksonville, FL (J.F.M.); University of Alabama at Birmingham (D.K.A., L.A.M.); Mayo Clinic Rochester, MN (R.D.B.); Massachusetts General Hospital, Boston, MA (H.A., J.R., O.W.); University of British Columbia, Vancouver, British Columbia, Canada (O.R.B.); University of Maryland School of Medicine and Veterans Administration Medical Center, Baltimore, MD (J.W.C., P.F.M., B.D.M., A.R.S., S.J.K.); University Medical Center Utrecht, Utrecht, The Netherlands (P.I.W.d.B.); Brigham and Women's Hospital, Harvard Medical School, Boston, MA (P.I.W.d.B.); Broad Institute of Harvard, MIT, Cambridge, MA (P.I.W.d.B.); Klinikum der Universität München, Ludwig-Maximilians-University, Munich, Germany (M.D.); Johns Hopkins University, Baltimore, MD (K.F.D.); University of Texas Health Science Center at Houston (M.F.); Saint Francis Medical Center, Lynwood, CA (R.P.G.); NINDS Neurogenetics Cluster, Bethesda, MD (K.G.); IMIM-Hospital Universitari del Mar, Barcelona, Spain (J.J.C.); University of Florida, College of Pharmacy, Gainesville, FL (J.A.J.); Institute of Neuroscience and Physiology, the Sahlgrenska Academy at University of Gothenburg, Sweden (K.J., C.J.); University of Washington, Seattle, WA (C.C.L.); Washington University School of Medicine, St. Louis, MO (J.-M.L.); Lund University, Lund, Sweden (A.L.); St. George's University of London, London, United Kingdom (H.S.M.); Medical University Graz, Graz, Austria (R.S.); Brigham and Women's Hospital, Boston, MA (K.M.R.); University of Virginia, Charlottesville, VA (S.S.R., B.B.W.); Radcliffe Infirmary, Oxford, England (P.M.R.); University of Miami, Coral Gables, FL (T.R., R.L.S.); Imperial College London, London, United Kingdom (P.S.); Jagiellonian University, Krakow, Poland (A.S.); Albert Einstein College of Medicine, Bronx, NY (S.W.-S.); University of Edinburgh, Edinburgh, United Kingdom (C.S.); Universitaire Ziekenhuizen Leuven, Leuven, Belgium (V.N.S.T.); and University of Cincinnati, Cincinnati, OH (

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http://dx.doi.org/10.1161/STROKEAHA.113.001857DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056331PMC
October 2013

Association of adiposity genetic variants with menarche timing in 92,105 women of European descent.

Am J Epidemiol 2013 Aug 4;178(3):451-60. Epub 2013 Apr 4.

Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, 137 East Franklin Street, Suite 306, Campus Box 8050, Chapel Hill, NC 27514-8050, USA.

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http://dx.doi.org/10.1093/aje/kws473DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816344PMC
August 2013

Amorphous solid dispersions of sulfonamide/Soluplus® and sulfonamide/PVP prepared by ball milling.

AAPS PharmSciTech 2013 Mar 7;14(1):464-74. Epub 2013 Feb 7.

School of Pharmacy and Pharmaceutical Sciences, Trinity College Dublin, University of Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1208/s12249-013-9931-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3581644PMC
March 2013

Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.

Authors:
Anna Köttgen Eva Albrecht Alexander Teumer Veronique Vitart Jan Krumsiek Claudia Hundertmark Giorgio Pistis Daniela Ruggiero Conall M O'Seaghdha Toomas Haller Qiong Yang Toshiko Tanaka Andrew D Johnson Zoltán Kutalik Albert V Smith Julia Shi Maksim Struchalin Rita P S Middelberg Morris J Brown Angelo L Gaffo Nicola Pirastu Guo Li Caroline Hayward Tatijana Zemunik Jennifer Huffman Loic Yengo Jing Hua Zhao Ayse Demirkan Mary F Feitosa Xuan Liu Giovanni Malerba Lorna M Lopez Pim van der Harst Xinzhong Li Marcus E Kleber Andrew A Hicks Ilja M Nolte Asa Johansson Federico Murgia Sarah H Wild Stephan J L Bakker John F Peden Abbas Dehghan Maristella Steri Albert Tenesa Vasiliki Lagou Perttu Salo Massimo Mangino Lynda M Rose Terho Lehtimäki Owen M Woodward Yukinori Okada Adrienne Tin Christian Müller Christopher Oldmeadow Margus Putku Darina Czamara Peter Kraft Laura Frogheri Gian Andri Thun Anne Grotevendt Gauti Kjartan Gislason Tamara B Harris Lenore J Launer Patrick McArdle Alan R Shuldiner Eric Boerwinkle Josef Coresh Helena Schmidt Michael Schallert Nicholas G Martin Grant W Montgomery Michiaki Kubo Yusuke Nakamura Toshihiro Tanaka Patricia B Munroe Nilesh J Samani David R Jacobs Kiang Liu Pio D'Adamo Sheila Ulivi Jerome I Rotter Bruce M Psaty Peter Vollenweider Gerard Waeber Susan Campbell Olivier Devuyst Pau Navarro Ivana Kolcic Nicholas Hastie Beverley Balkau Philippe Froguel Tõnu Esko Andres Salumets Kay Tee Khaw Claudia Langenberg Nicholas J Wareham Aaron Isaacs Aldi Kraja Qunyuan Zhang Philipp S Wild Rodney J Scott Elizabeth G Holliday Elin Org Margus Viigimaa Stefania Bandinelli Jeffrey E Metter Antonio Lupo Elisabetta Trabetti Rossella Sorice Angela Döring Eva Lattka Konstantin Strauch Fabian Theis Melanie Waldenberger H-Erich Wichmann Gail Davies Alan J Gow Marcel Bruinenberg Ronald P Stolk Jaspal S Kooner Weihua Zhang Bernhard R Winkelmann Bernhard O Boehm Susanne Lucae Brenda W Penninx Johannes H Smit Gary Curhan Poorva Mudgal Robert M Plenge Laura Portas Ivana Persico Mirna Kirin James F Wilson Irene Mateo Leach Wiek H van Gilst Anuj Goel Halit Ongen Albert Hofman Fernando Rivadeneira Andre G Uitterlinden Medea Imboden Arnold von Eckardstein Francesco Cucca Ramaiah Nagaraja Maria Grazia Piras Matthias Nauck Claudia Schurmann Kathrin Budde Florian Ernst Susan M Farrington Evropi Theodoratou Inga Prokopenko Michael Stumvoll Antti Jula Markus Perola Veikko Salomaa So-Youn Shin Tim D Spector Cinzia Sala Paul M Ridker Mika Kähönen Jorma Viikari Christian Hengstenberg Christopher P Nelson James F Meschia Michael A Nalls Pankaj Sharma Andrew B Singleton Naoyuki Kamatani Tanja Zeller Michel Burnier John Attia Maris Laan Norman Klopp Hans L Hillege Stefan Kloiber Hyon Choi Mario Pirastu Silvia Tore Nicole M Probst-Hensch Henry Völzke Vilmundur Gudnason Afshin Parsa Reinhold Schmidt John B Whitfield Myriam Fornage Paolo Gasparini David S Siscovick Ozren Polašek Harry Campbell Igor Rudan Nabila Bouatia-Naji Andres Metspalu Ruth J F Loos Cornelia M van Duijn Ingrid B Borecki Luigi Ferrucci Giovanni Gambaro Ian J Deary Bruce H R Wolffenbuttel John C Chambers Winfried März Peter P Pramstaller Harold Snieder Ulf Gyllensten Alan F Wright Gerjan Navis Hugh Watkins Jacqueline C M Witteman Serena Sanna Sabine Schipf Malcolm G Dunlop Anke Tönjes Samuli Ripatti Nicole Soranzo Daniela Toniolo Daniel I Chasman Olli Raitakari W H Linda Kao Marina Ciullo Caroline S Fox Mark Caulfield Murielle Bochud Christian Gieger

Nat Genet 2013 Feb 23;45(2):145-54. Epub 2012 Dec 23.

Renal Division, Freiburg University Hospital, Freiburg, Germany.

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http://dx.doi.org/10.1038/ng.2500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3663712PMC
February 2013

Formation, physical stability, and quantification of process-induced disorder in cryomilled samples of a model polymorphic drug.

J Pharm Sci 2013 Jan 9;102(1):93-103. Epub 2012 Oct 9.

School of Chemistry, National University of Ireland, Galway, Galway, Ireland.

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http://dx.doi.org/10.1002/jps.23338DOI Listing
January 2013

Investigation of the capacity of low glass transition temperature excipients to minimize amorphization of sulfadimidine on comilling.

Mol Pharm 2013 Jan 5;10(1):386-96. Epub 2012 Dec 5.

School of Pharmacy and Pharmaceutical Sciences, University of Dublin, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1021/mp300529aDOI Listing
January 2013

17β-Hy-droxy-17α-methyl-androsta-1,4-dien-3-one.

Acta Crystallogr Sect E Struct Rep Online 2013 Jan 8;69(Pt 1):o60. Epub 2012 Dec 8.

School of Chemistry, National University of Ireland, Galway, University Road, Galway, Ireland.

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http://scripts.iucr.org/cgi-bin/paper?S1600536812049860
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http://dx.doi.org/10.1107/S1600536812049860DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3588272PMC
January 2013

Ethyl N-[2-(4-phen-oxy-phen-oxy)eth-yl]carbamate.

Acta Crystallogr Sect E Struct Rep Online 2012 Oct 5;68(Pt 10):o2834-5. Epub 2012 Sep 5.

School of Chemistry, National University of Ireland, Galway, University road, Galway, Ireland.

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http://dx.doi.org/10.1107/S1600536812037105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470196PMC
October 2012

Genotype-based changes in serum uric acid affect blood pressure.

Kidney Int 2012 Mar 21;81(5):502-7. Epub 2011 Dec 21.

Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00852538155533
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http://dx.doi.org/10.1038/ki.2011.414DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3640827PMC
March 2012

Association between bilirubin and cardiovascular disease risk factors: using Mendelian randomization to assess causal inference.

BMC Cardiovasc Disord 2012 Mar 14;12:16. Epub 2012 Mar 14.

Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, 660 West Redwood Street, Rm, 492, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1186/1471-2261-12-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313889PMC
March 2012

Common genetic variation in the 3'-BCL11B gene desert is associated with carotid-femoral pulse wave velocity and excess cardiovascular disease risk: the AortaGen Consortium.

Circ Cardiovasc Genet 2012 Feb 8;5(1):81-90. Epub 2011 Nov 8.

Cardiovascular Engineering Inc., 1 Edgewater Drive, Norwood, MA 02062, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288392PMC
http://dx.doi.org/10.1161/CIRCGENETICS.111.959817DOI Listing
February 2012

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.

Authors:
Lisette Stolk John R B Perry Daniel I Chasman Chunyan He Massimo Mangino Patrick Sulem Maja Barbalic Linda Broer Enda M Byrne Florian Ernst Tõnu Esko Nora Franceschini Daniel F Gudbjartsson Jouke-Jan Hottenga Peter Kraft Patrick F McArdle Eleonora Porcu So-Youn Shin Albert V Smith Sophie van Wingerden Guangju Zhai Wei V Zhuang Eva Albrecht Behrooz Z Alizadeh Thor Aspelund Stefania Bandinelli Lovorka Barac Lauc Jacques S Beckmann Mladen Boban Eric Boerwinkle Frank J Broekmans Andrea Burri Harry Campbell Stephen J Chanock Constance Chen Marilyn C Cornelis Tanguy Corre Andrea D Coviello Pio d'Adamo Gail Davies Ulf de Faire Eco J C de Geus Ian J Deary George V Z Dedoussis Panagiotis Deloukas Shah Ebrahim Gudny Eiriksdottir Valur Emilsson Johan G Eriksson Bart C J M Fauser Liana Ferreli Luigi Ferrucci Krista Fischer Aaron R Folsom Melissa E Garcia Paolo Gasparini Christian Gieger Nicole Glazer Diederick E Grobbee Per Hall Toomas Haller Susan E Hankinson Merli Hass Caroline Hayward Andrew C Heath Albert Hofman Erik Ingelsson A Cecile J W Janssens Andrew D Johnson David Karasik Sharon L R Kardia Jules Keyzer Douglas P Kiel Ivana Kolcic Zoltán Kutalik Jari Lahti Sandra Lai Triin Laisk Joop S E Laven Debbie A Lawlor Jianjun Liu Lorna M Lopez Yvonne V Louwers Patrik K E Magnusson Mara Marongiu Nicholas G Martin Irena Martinovic Klaric Corrado Masciullo Barbara McKnight Sarah E Medland David Melzer Vincent Mooser Pau Navarro Anne B Newman Dale R Nyholt N Charlotte Onland-Moret Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Petra H M Peeters Giorgio Pistis Andrew S Plump Ozren Polasek Victor J M Pop Bruce M Psaty Katri Räikkönen Emil Rehnberg Jerome I Rotter Igor Rudan Cinzia Sala Andres Salumets Angelo Scuteri Andrew Singleton Jennifer A Smith Harold Snieder Nicole Soranzo Simon N Stacey John M Starr Maria G Stathopoulou Kathleen Stirrups Ronald P Stolk Unnur Styrkarsdottir Yan V Sun Albert Tenesa Barbara Thorand Daniela Toniolo Laufey Tryggvadottir Kim Tsui Sheila Ulivi Rob M van Dam Yvonne T van der Schouw Carla H van Gils Peter van Nierop Jacqueline M Vink Peter M Visscher Marlies Voorhuis Gérard Waeber Henri Wallaschofski H Erich Wichmann Elisabeth Widen Colette J M Wijnands-van Gent Gonneke Willemsen James F Wilson Bruce H R Wolffenbuttel Alan F Wright Laura M Yerges-Armstrong Tatijana Zemunik Lina Zgaga M Carola Zillikens Marek Zygmunt Alice M Arnold Dorret I Boomsma Julie E Buring Laura Crisponi Ellen W Demerath Vilmundur Gudnason Tamara B Harris Frank B Hu David J Hunter Lenore J Launer Andres Metspalu Grant W Montgomery Ben A Oostra Paul M Ridker Serena Sanna David Schlessinger Tim D Spector Kari Stefansson Elizabeth A Streeten Unnur Thorsteinsdottir Manuela Uda André G Uitterlinden Cornelia M van Duijn Henry Völzke Anna Murray Joanne M Murabito Jenny A Visser Kathryn L Lunetta

Nat Genet 2012 Jan 22;44(3):260-8. Epub 2012 Jan 22.

Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.1051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288642PMC
January 2012

Asymmetric organocatalytic 1,6-conjugate addition of aldehydes to dienic sulfones.

Angew Chem Int Ed Engl 2011 May 28;50(22):5095-8. Epub 2011 Apr 28.

Department of Chemistry, National University of Ireland Maynooth, Co. Kildare, Ireland.

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http://dx.doi.org/10.1002/anie.201100804DOI Listing
May 2011

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

Authors:
Cathy E Elks John R B Perry Patrick Sulem Daniel I Chasman Nora Franceschini Chunyan He Kathryn L Lunetta Jenny A Visser Enda M Byrne Diana L Cousminer Daniel F Gudbjartsson Tõnu Esko Bjarke Feenstra Jouke-Jan Hottenga Daniel L Koller Zoltán Kutalik Peng Lin Massimo Mangino Mara Marongiu Patrick F McArdle Albert V Smith Lisette Stolk Sophie H van Wingerden Jing Hua Zhao Eva Albrecht Tanguy Corre Erik Ingelsson Caroline Hayward Patrik K E Magnusson Erin N Smith Shelia Ulivi Nicole M Warrington Lina Zgaga Helen Alavere Najaf Amin Thor Aspelund Stefania Bandinelli Inês Barroso Gerald S Berenson Sven Bergmann Hannah Blackburn Eric Boerwinkle Julie E Buring Fabio Busonero Harry Campbell Stephen J Chanock Wei Chen Marilyn C Cornelis David Couper Andrea D Coviello Pio d'Adamo Ulf de Faire Eco J C de Geus Panos Deloukas Angela Döring George Davey Smith Douglas F Easton Gudny Eiriksdottir Valur Emilsson Johan Eriksson Luigi Ferrucci Aaron R Folsom Tatiana Foroud Melissa Garcia Paolo Gasparini Frank Geller Christian Gieger Vilmundur Gudnason Per Hall Susan E Hankinson Liana Ferreli Andrew C Heath Dena G Hernandez Albert Hofman Frank B Hu Thomas Illig Marjo-Riitta Järvelin Andrew D Johnson David Karasik Kay-Tee Khaw Douglas P Kiel Tuomas O Kilpeläinen Ivana Kolcic Peter Kraft Lenore J Launer Joop S E Laven Shengxu Li Jianjun Liu Daniel Levy Nicholas G Martin Wendy L McArdle Mads Melbye Vincent Mooser Jeffrey C Murray Sarah S Murray Michael A Nalls Pau Navarro Mari Nelis Andrew R Ness Kate Northstone Ben A Oostra Munro Peacock Lyle J Palmer Aarno Palotie Guillaume Paré Alex N Parker Nancy L Pedersen Leena Peltonen Craig E Pennell Paul Pharoah Ozren Polasek Andrew S Plump Anneli Pouta Eleonora Porcu Thorunn Rafnar John P Rice Susan M Ring Fernando Rivadeneira Igor Rudan Cinzia Sala Veikko Salomaa Serena Sanna David Schlessinger Nicholas J Schork Angelo Scuteri Ayellet V Segrè Alan R Shuldiner Nicole Soranzo Ulla Sovio Sathanur R Srinivasan David P Strachan Mar-Liis Tammesoo Emmi Tikkanen Daniela Toniolo Kim Tsui Laufey Tryggvadottir Jonathon Tyrer Manuela Uda Rob M van Dam Joyce B J van Meurs Peter Vollenweider Gerard Waeber Nicholas J Wareham Dawn M Waterworth Michael N Weedon H Erich Wichmann Gonneke Willemsen James F Wilson Alan F Wright Lauren Young Guangju Zhai Wei Vivian Zhuang Laura J Bierut Dorret I Boomsma Heather A Boyd Laura Crisponi Ellen W Demerath Cornelia M van Duijn Michael J Econs Tamara B Harris David J Hunter Ruth J F Loos Andres Metspalu Grant W Montgomery Paul M Ridker Tim D Spector Elizabeth A Streeten Kari Stefansson Unnur Thorsteinsdottir André G Uitterlinden Elisabeth Widen Joanne M Murabito Ken K Ong Anna Murray

Nat Genet 2010 Dec;42(12):1077-85

Medical Research Council (MRC) Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1038/ng.714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140055PMC
December 2010

Quantitative analysis of sulfathiazole polymorphs in ternary mixtures by attenuated total reflectance infrared, near-infrared and Raman spectroscopy.

J Pharm Biomed Anal 2010 Nov 10;53(3):412-20. Epub 2010 May 10.

School of Chemistry, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1016/j.jpba.2010.05.002DOI Listing
November 2010

Access to resorcylic acid lactones via phosphonate based intramolecular olefination.

J Org Chem 2010 Nov;75(21):7404-7

School of Chemistry, National University of Ireland, Galway, University Road, Galway, Ireland.

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http://dx.doi.org/10.1021/jo100998bDOI Listing
November 2010

A family of double-bowl pseudo metallocalix[6]arene discs.

Dalton Trans 2010 May;39(20):4809-16

School of Chemistry, University Road, National University of Ireland, Galway, Ireland.

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http://dx.doi.org/10.1039/b926704bDOI Listing
May 2010

A F-bridged Mn(II) molecular square.

Chem Commun (Camb) 2009 Dec 8(45):7024-6. Epub 2009 Oct 8.

School of Chemistry, National University of Ireland, Galway, University Road, Galway, Ireland.

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http://dx.doi.org/10.1039/b916153hDOI Listing
December 2009

A molecular mechanics approach to mapping the conformational space of diaryl and triarylphosphines.

Dalton Trans 2006 Dec 13(46):5464-75. Epub 2006 Oct 13.

School of Chemistry, Cantock's Close, Clifton, Bristol, UKBS8 1TS.

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http://dx.doi.org/10.1039/b610123bDOI Listing
December 2006

1,3-Dipolar character of 2-vinyl quinazoline 3-oxides; first and second generation cycloaddition products.

Org Biomol Chem 2006 Jun 11;4(12):2408-16. Epub 2006 May 11.

Department of Chemistry, National University of Ireland, Maynooth, Ireland.

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http://dx.doi.org/10.1039/b602423hDOI Listing
June 2006

Does having children extend life span? A genealogical study of parity and longevity in the Amish.

J Gerontol A Biol Sci Med Sci 2006 Feb;61(2):190-5

Department of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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http://dx.doi.org/10.1093/gerona/61.2.190DOI Listing
February 2006

Alpha-oximono-esters as precursors to heterocycles--generation of oxazinone N-oxides and cycloaddition to alkene dipolarophiles.

Org Biomol Chem 2003 Dec 29;1(23):4302-16. Epub 2003 Oct 29.

Department of Chemistry, National University of Ireland, Maynooth, Ireland.

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http://dx.doi.org/10.1039/b307077hDOI Listing
December 2003