Publications by authors named "Patrick Kwok-Shing Ng"

30Publications

Comprehensive assessment of computational algorithms in predicting cancer driver mutations.

Genome Biol 2020 02 20;21(1):43. Epub 2020 Feb 20.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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February 2020

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.

Cell Rep 2018 10;25(5):1304-1317.e5

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Program in Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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October 2018

Hypermethylation of NF-κB-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis.

Dig Dis Sci 2018 03 20;63(3):676-686. Epub 2018 Jan 20.

School of Biomedical Sciences, The Chinese University of Hong Kong, Room 524, Lo Kwee-Seong Integrated Biomedical Sciences Building, Area 39, Hong Kong, China.

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March 2018

Unique protein expression signatures of survival time in kidney renal clear cell carcinoma through a pan-cancer screening.

BMC Genomics 2017 Oct 3;18(Suppl 6):678. Epub 2017 Oct 3.

Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St., Suite 820, Houston, TX, 77030, USA.

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October 2017

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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June 2017

Ba/F3 transformation assays.

Oncotarget 2017 May;8(22):35488-35489

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

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May 2017

RET fusion as a novel driver of medullary thyroid carcinoma.

J Clin Endocrinol Metab 2015 Mar 29;100(3):788-93. Epub 2014 Dec 29.

Departments of Surgical Oncology (E.G.G., J.B., J.E.L., F.M.-B., N.D.P.), Institute of Personalized Cancer Therapy (P.K.-S.N., K.R.S.), Endocrine Neoplasia and Hormonal Disorders (N.L.B., S.G.W., G.J.C.), Bioinformatics and Computational Biology (K.C.), Hematopathology (X.L.), Investigational Cancer Therapeutics (F.M.-B.), Systems Biology (G.B.M.), and Pathology (M.D.W.), University of Texas MD Anderson Cancer Center, Houston, Texas 77030; Foundation Medicine (G.P., R.Y.), Cambridge, Massachusetts 02141; and Integrative Molecular and Biomedical Sciences Graduate Program (H.L., K.L.S.), Baylor College of Medicine, Houston, Texas 77030.

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March 2015

The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens.

J Allergy Clin Immunol 2015 Feb 31;135(2):539-48. Epub 2014 Oct 31.

Hong Kong Bioinformatics Centre, Chinese University of Hong Kong, Hong Kong, China; School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China. Electronic address:

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February 2015

A comprehensive evaluation of biomarkers predictive of response to PI3K inhibitors and of resistance mechanisms in head and neck squamous cell carcinoma.

Mol Cancer Ther 2014 Nov 5;13(11):2738-50. Epub 2014 Sep 5.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences, Houston, Texas.

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November 2014

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer.

Proc Natl Acad Sci U S A 2014 Jan 6;111(3):1114-9. Epub 2014 Jan 6.

Departments of Otolaryngology, Pharmacology and Chemical Biology, Structural Biology, and Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.

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January 2014