Publications by authors named "Patrick Kwok-Shing Ng"

30Publications

Comprehensive assessment of computational algorithms in predicting cancer driver mutations.

Genome Biol 2020 02 20;21(1):43. Epub 2020 Feb 20.

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s13059-020-01954-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7033911PMC
February 2020

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer.

Cell Rep 2018 10;25(5):1304-1317.e5

Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Graduate Program in Quantitative and Computational Biosciences, Baylor College of Medicine, Houston, TX 77030, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183156
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http://dx.doi.org/10.1016/j.celrep.2018.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326181PMC
October 2018

Hypermethylation of NF-κB-Activating Protein-Like (NKAPL) Promoter in Hepatocellular Carcinoma Suppresses Its Expression and Predicts a Poor Prognosis.

Dig Dis Sci 2018 03 20;63(3):676-686. Epub 2018 Jan 20.

School of Biomedical Sciences, The Chinese University of Hong Kong, Room 524, Lo Kwee-Seong Integrated Biomedical Sciences Building, Area 39, Hong Kong, China.

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http://dx.doi.org/10.1007/s10620-018-4929-3DOI Listing
March 2018

Unique protein expression signatures of survival time in kidney renal clear cell carcinoma through a pan-cancer screening.

BMC Genomics 2017 Oct 3;18(Suppl 6):678. Epub 2017 Oct 3.

Center for Precision Health, School of Biomedical Informatics, The University of Texas Health Science Center at Houston, 7000 Fannin St., Suite 820, Houston, TX, 77030, USA.

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http://dx.doi.org/10.1186/s12864-017-4026-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629613PMC
October 2017

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations.

Cancer Cell 2017 06 18;31(6):820-832.e3. Epub 2017 May 18.

Dan L. Duncan Comprehensive Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA; Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2017.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5502825PMC
June 2017

Ba/F3 transformation assays.

Oncotarget 2017 May;8(22):35488-35489

Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.17828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482591PMC
May 2017

RET fusion as a novel driver of medullary thyroid carcinoma.

J Clin Endocrinol Metab 2015 Mar 29;100(3):788-93. Epub 2014 Dec 29.

Departments of Surgical Oncology (E.G.G., J.B., J.E.L., F.M.-B., N.D.P.), Institute of Personalized Cancer Therapy (P.K.-S.N., K.R.S.), Endocrine Neoplasia and Hormonal Disorders (N.L.B., S.G.W., G.J.C.), Bioinformatics and Computational Biology (K.C.), Hematopathology (X.L.), Investigational Cancer Therapeutics (F.M.-B.), Systems Biology (G.B.M.), and Pathology (M.D.W.), University of Texas MD Anderson Cancer Center, Houston, Texas 77030; Foundation Medicine (G.P., R.Y.), Cambridge, Massachusetts 02141; and Integrative Molecular and Biomedical Sciences Graduate Program (H.L., K.L.S.), Baylor College of Medicine, Houston, Texas 77030.

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http://dx.doi.org/10.1210/jc.2014-4153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333032PMC
March 2015

The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens.

J Allergy Clin Immunol 2015 Feb 31;135(2):539-48. Epub 2014 Oct 31.

Hong Kong Bioinformatics Centre, Chinese University of Hong Kong, Hong Kong, China; School of Biomedical Sciences, Chinese University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.09.031DOI Listing
February 2015

A comprehensive evaluation of biomarkers predictive of response to PI3K inhibitors and of resistance mechanisms in head and neck squamous cell carcinoma.

Mol Cancer Ther 2014 Nov 5;13(11):2738-50. Epub 2014 Sep 5.

Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. The University of Texas Graduate School of Biomedical Sciences, Houston, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-13-1090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4221385PMC
November 2014

Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer.

Proc Natl Acad Sci U S A 2014 Jan 6;111(3):1114-9. Epub 2014 Jan 6.

Departments of Otolaryngology, Pharmacology and Chemical Biology, Structural Biology, and Computational and Systems Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213.

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http://dx.doi.org/10.1073/pnas.1319551111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3903220PMC
January 2014

Full-length Mst1 exhibits growth promoting function in human hepatocellular carcinoma cells.

FEBS Lett 2013 Mar 21;587(5):496-503. Epub 2013 Jan 21.

Department of Pharmacology and Chemical Biology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15232, USA.

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http://dx.doi.org/10.1016/j.febslet.2013.01.018DOI Listing
March 2013

p63 regulates cell proliferation and cell cycle progression‑associated genes in stromal cells of giant cell tumor of the bone.

Int J Oncol 2013 Feb 3;42(2):437-43. Epub 2012 Dec 3.

Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong, SAR, P.R. China.

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http://dx.doi.org/10.3892/ijo.2012.1727DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583652PMC
February 2013

Characterization of human FHL2 transcript variants and gene expression regulation in hepatocellular carcinoma.

Gene 2011 Jul 22;481(1):41-7. Epub 2011 Apr 22.

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong.

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http://dx.doi.org/10.1016/j.gene.2011.04.005DOI Listing
July 2011

FHL2 exhibits anti-proliferative and anti-apoptotic activities in liver cancer cells.

Cancer Lett 2011 May 5;304(2):97-106. Epub 2011 Mar 5.

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, NT, Hong Kong.

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http://dx.doi.org/10.1016/j.canlet.2011.02.001DOI Listing
May 2011

Transcriptional regulation and functional implication of the grass carp CITED1 (gcCITED1) in the negative regulation of HIF-1.

Int J Biochem Cell Biol 2010 Sep 12;42(9):1544-52. Epub 2010 Jun 12.

Department of Biochemistry, Chinese University of Hong Kong, New Territories, Hong Kong Special Administrative Region, China.

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https://linkinghub.elsevier.com/retrieve/pii/S13572725100020
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http://dx.doi.org/10.1016/j.biocel.2010.06.007DOI Listing
September 2010

CCAAT/enhancer binding protein beta is up-regulated in giant cell tumor of bone and regulates RANKL expression.

J Cell Biochem 2010 May;110(2):438-46

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR.

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http://doi.wiley.com/10.1002/jcb.22556
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http://dx.doi.org/10.1002/jcb.22556DOI Listing
May 2010

Enhancement of hypoxia-induced gene expression in fish liver by the aryl hydrocarbon receptor (AhR) ligand, benzo[a]pyrene (BaP).

Aquat Toxicol 2008 Nov 12;90(3):235-42. Epub 2008 Sep 12.

Department of Biology and Chemistry, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong, China.

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https://linkinghub.elsevier.com/retrieve/pii/S0166445X080029
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http://dx.doi.org/10.1016/j.aquatox.2008.09.004DOI Listing
November 2008