Patrick Kwan

Patrick Kwan

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Patrick Kwan

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Distinct psychopathology profiles in patients with epileptic seizures compared to non-epileptic psychogenic seizures.

Epilepsy Res 2019 Dec 1;158:106234. Epub 2019 Nov 1.

Clinical Outcomes Research Unit (CORe), Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Australia; Melbourne School of Psychological Sciences, The University of Melbourne, Australia; Department of Neurosciences, Monash University, Australia; Department of Neurology, Alfred Health, Australia; Department of Neurology, Royal Melbourne Hospital, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.eplepsyres.2019.106234DOI Listing
December 2019

Abbreviated assessment of psychopathology in patients with suspected seizure disorders.

Epilepsy Behav 2019 Nov 25;100(Pt A):106530. Epub 2019 Oct 25.

Department of Psychiatry, Royal Melbourne Hospital, Australia; Department of Psychiatry, The University of Melbourne, Australia.

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http://dx.doi.org/10.1016/j.yebeh.2019.106530DOI Listing
November 2019

Relative Seizure Relapse Risks Associated with Antiepileptic Drug Withdrawal After Different Seizure-Free Periods in Adults with Focal Epilepsy: A Prospective, Controlled Follow-Up Study.

CNS Drugs 2019 Nov;33(11):1121-1132

Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China.

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http://dx.doi.org/10.1007/s40263-019-00679-3DOI Listing
November 2019

Tau Related Pathways as a Connecting Link between Epilepsy and Alzheimer's Disease.

ACS Chem Neurosci 2019 Oct 30;10(10):4199-4212. Epub 2019 Sep 30.

Neuropharmacology Research Laboratory, Jeffrey Cheah School of Medicine and Health Sciences , Monash University Malaysia , Bandar Sunway , Selangor 46150 , Malaysia.

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http://dx.doi.org/10.1021/acschemneuro.9b00460DOI Listing
October 2019

Personality profiles differ between patients with epileptic seizures and patients with psychogenic non-epileptic seizures.

Seizure 2019 Oct 17;73:1-8. Epub 2019 Oct 17.

Clinical Outcomes Research Unit (CORe), Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, 3010, Australia; Melbourne School of Psychological Sciences, The University of Melbourne, Parkville, Victoria, 3010, Australia; Department of Neuroscience, Monash University, Clayton, Victoria, 3800, Australia; Department of Neurology, Alfred Health, Melbourne, Victoria, 3004, Australia; Department of Neurology, Royal Melbourne Hospital, Parkville, Victoria, 3010, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2019.10.011DOI Listing
October 2019

First seizure presentations in adults: beyond assessment and treatment.

J Neurol Neurosurg Psychiatry 2019 Sep 4;90(9):1039-1045. Epub 2019 Apr 4.

Neurology, Alfred Health, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1136/jnnp-2018-320215DOI Listing
September 2019

Pharmacoresistance - Epidemiology, mechanisms, and impact on epilepsy treatment.

Neuropharmacology 2019 Sep 24:107790. Epub 2019 Sep 24.

Department of Neuroscience, Alfred Hospital, Central Clinical School, Monash University, Melbourne, Victoria, Australia; Departments of Medicine and Neurology, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neuropharm.2019.107790DOI Listing
September 2019

Cross-ethnicity tagging SNPs for HLA alleles associated with adverse drug reaction.

Pharmacogenomics J 2019 06 10;19(3):230-239. Epub 2018 Aug 10.

Centre for Neural Engineering, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/s41397-018-0039-zDOI Listing
June 2019

Bilateral volume reduction in posterior hippocampus in psychosis of epilepsy.

J Neurol Neurosurg Psychiatry 2019 Jun 22;90(6):688-694. Epub 2019 Feb 22.

Melbourne School of Psychological Sciences, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1136/jnnp-2018-319396DOI Listing
June 2019

HLA-associated antiepileptic drug-induced cutaneous adverse reactions.

HLA 2019 Jun 9;93(6):417-435. Epub 2019 Apr 9.

Infection and Immunity Program, Monash Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1111/tan.13530DOI Listing
June 2019

Commentary on "Do neurologists agree in diagnosing drug resistance in adults with focal epilepsy?"

Authors:
Patrick Kwan

Epilepsia 2019 Jun 9;60(6):1124-1125. Epub 2019 May 9.

Department of Neuroscience, Central Clinical School, Alfred Hospital, Monash University, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.14886DOI Listing
June 2019

Pharmacological outcomes in teenagers with newly diagnosed epilepsy: A 30-year cohort study.

Epilepsia 2019 Jun 21;60(6):1083-1090. Epub 2019 May 21.

University of Glasgow, Glasgow, Scotland, UK.

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http://dx.doi.org/10.1111/epi.15664DOI Listing
June 2019

The utility of an automated and ambulatory device for detecting and differentiating epileptic and psychogenic non-epileptic seizures.

Epilepsia Open 2019 Jun 13;4(2):309-317. Epub 2019 May 13.

Departments of Neurology and Medicine The Melbourne Brain Centre, The Royal Melbourne Hospital Parkville Victoria Australia.

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http://dx.doi.org/10.1002/epi4.12327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6546070PMC
June 2019

Development of an Ultrasensitive Impedimetric Immunosensor Platform for Detection of Lactate Dehydrogenase.

Sensors (Basel) 2019 May 29;19(11). Epub 2019 May 29.

Department of Medicine, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, 792 Elizabeth Street, Melbourne, VIC 3000, Australia.

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http://dx.doi.org/10.3390/s19112446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603725PMC
May 2019

The Concept of Drug-Resistant Epileptogenic Zone.

Front Neurol 2019 31;10:558. Epub 2019 May 31.

Department of Neuroscience, Alfred Hospital, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fneur.2019.00558DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6555267PMC
May 2019

The safety of treating newly diagnosed epilepsy.

Expert Opin Drug Saf 2019 04 11;18(4):273-283. Epub 2019 Apr 11.

a Department of Neuroscience , Central Clinical School, Monash University , Melbourne , Australia.

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http://dx.doi.org/10.1080/14740338.2019.1602607DOI Listing
April 2019

Epilepsy in Asia: Disease burden, management barriers, and challenges.

Epilepsia 2019 Mar 28;60 Suppl 1:7-21. Epub 2018 Jun 28.

Eisai Singapore Pte Ltd, Singapore.

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http://dx.doi.org/10.1111/epi.14458DOI Listing
March 2019

Targeting neurodegeneration to prevent post-traumatic epilepsy.

Neurobiol Dis 2019 03 9;123:100-109. Epub 2018 Aug 9.

Department of Neuroscience, Central Clinical School, Monash University, The Alfred Hospital, Melbourne, Australia; Department of Medicine (Royal Melbourne Hospital), The University of Melbourne, Melbourne, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09699961183042
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http://dx.doi.org/10.1016/j.nbd.2018.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348126PMC
March 2019

Randomized trial of add-on triheptanoin vs medium chain triglycerides in adults with refractory epilepsy.

Epilepsia Open 2019 Mar 22;4(1):153-163. Epub 2019 Feb 22.

Departments of Medicine and Neurology Royal Melbourne Hospital University of Melbourne Parkville Victoria Australia.

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http://dx.doi.org/10.1002/epi4.12308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398112PMC
March 2019

Metabolic patterns and seizure outcomes following anterior temporal lobectomy.

Ann Neurol 2019 Feb 17;85(2):241-250. Epub 2019 Jan 17.

Departments of Medicine and Neurology, Melbourne Brain Centre, University of Melbourne, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/ana.25405DOI Listing
February 2019

Oral health and dental status in people with epilepsy in rural China.

Seizure 2019 Feb 28;65:42-47. Epub 2018 Dec 28.

NIHR University College London Hospitals Biomedical Research Centre, UCL Queen Square Institute of Neurology, Queen Square, London, WC1N 3BG, United Kingdom; Chalfont Centre for Epilepsy, Chalfont St Peter, SL9 0RJ, United Kingdom; Stichting Epilepsie Instellingen Nederland (SEIN), Achterweg 5, Heemstede, 2103 SW, the Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S10591311183059
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http://dx.doi.org/10.1016/j.seizure.2018.12.022DOI Listing
February 2019

Determining the cost of first-ever seizures: A narrative review and future directions.

Epilepsy Behav 2019 01 23;90:291-294. Epub 2018 Nov 23.

Department of Neurology, Alfred Health, Commercial Road, Melbourne, VIC 3000, Australia; Department of Neurology, The Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3052, Australia; Department of Neuroscience, Central Clinical School, Monash University, Melbourne, VIC 3000, Australia.

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http://dx.doi.org/10.1016/j.yebeh.2018.10.045DOI Listing
January 2019

Novel features for capturing temporal variations of rhythmic limb movement to distinguish convulsive epileptic and psychogenic nonepileptic seizures.

Epilepsia 2019 Jan 9;60(1):165-174. Epub 2018 Dec 9.

Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.14619DOI Listing
January 2019

Sleep-disordered breathing among patients admitted for inpatient video-EEG monitoring.

Neurology 2019 01 14;92(3):e194-e204. Epub 2018 Dec 14.

From the Departments of Medicine (S.S., Z.C., A.P., C.J.R., N.C.J., C.F., P.P., P.K., T.J.O.), Neurology (S.S., E.J.W., A.P., C.H., J.C., C.J.R., R.Y., C.F., P.P., P.K., T.J.O.), and Respiratory and Sleep Disorders Medicine (T.M., J.G.), The Royal Melbourne Hospital, The University of Melbourne, Parkville; Department of Neuroscience (S.S., Z.C., A.P., N.C.J., C.F., P.P., P.K., T.J.O.), Central Clinical School, Monash University; Department of Neurology (S.S., A.P., P.P., P.K., T.J.O.), The Alfred Hospital; and Neuropsychiatry Unit (S.F., D.V.), The Royal Melbourne Hospital and Melbourne Neuropsychiatry Centre, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000006776DOI Listing
January 2019

Generalized polyspike train: An EEG biomarker of drug-resistant idiopathic generalized epilepsy.

Neurology 2018 11 12;91(19):e1822-e1830. Epub 2018 Oct 12.

From the Department of Neurology (Y.S.), The Affiliated Hospital of Qingdao University, Qingdao, China; Department of Neurology (Y.S.), Xuanwu Hospital, Capital Medical University, Beijing, China; Departments of Neurology (Y.S., P.P., M.K.T., T.J.O., P.K.) and Medicine (P.P., Z.C., T.J.O., P.K.), The Royal Melbourne Hospital, The University of Melbourne, Victoria; Department of Medicine (U.S., W.D.), St. Vincent's Hospital Melbourne, The University of Melbourne, Victoria; Department of Medicine, The School of Clinical Sciences at Monash Health (U.S.), and Departments of Neuroscience, The Central Clinical School (P.P., T.J.O., P.K.), Monash University, Victoria; and Department of Neurology (P.P., T.J.O., P.K.), The Alfred Hospital, Victoria, Australia.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006472DOI Listing
November 2018

New-onset epilepsy in the elderly.

Br J Clin Pharmacol 2018 10 28;84(10):2208-2217. Epub 2018 Jul 28.

Melbourne Brain Centre at the Royal Melbourne Hospital; Departments of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, 3050, Australia.

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http://dx.doi.org/10.1111/bcp.13653DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6138506PMC
October 2018

The Association Between Atrial Fibrillation and Poststroke Seizures is Influenced by Ethnicity and Environmental Factors.

J Stroke Cerebrovasc Dis 2018 Oct 21;27(10):2755-2760. Epub 2018 Jul 21.

Melbourne Brain Centre, Royal Melbourne Hospital and Department of Medicine, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.05.044DOI Listing
October 2018

Presentation and management of community-onset vs hospital-onset first seizures.

Neurol Clin Pract 2018 Oct;8(5):421-428

Department of Neurosciences (EF, PK), Alfred Health, Prahran; Cabrini Health (EF, PK), Malvern; Department of Neurology (EF, SH, PK), The Royal Melbourne Hospital, Parkville; Central Clinical School (EF, PK), Monash University, Melbourne; Department of Medicine (ZC), The Royal Melbourne Hospital, The University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1212/CPJ.0000000000000524DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6276335PMC
October 2018

An interdigitated electrode biosensor platform for rapid HLA-B*15:02 genotyping for prevention of drug hypersensitivity.

Biosens Bioelectron 2018 Jul 2;111:174-183. Epub 2018 Feb 2.

Department of Medicine, The University of Melbourne, Royal Melbourne Hospital, Victoria 3050, Australia; Department of Electrical and Electronic Engineering, Melbourne School of Engineering, The University of Melbourne, Victoria 3010, Australia; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09565663183007
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http://dx.doi.org/10.1016/j.bios.2018.01.063DOI Listing
July 2018

Rare variants and de novo variants in mesial temporal lobe epilepsy with hippocampal sclerosis.

Neurol Genet 2018 Jun 11;4(3):e245. Epub 2018 Jun 11.

Centre for Genomic Sciences and Department of Psychiatry (J.K.L.W., H.G., L.B., P.C.S., S.S.C.), Li Ka Shing Faculty of Medicine, The University of Hong Kong; Department of Medicine and Therapeutics (M.K., P.K.), The Chinese University of Hong Kong; Department of Medicine (P.W.N.), United Christian Hospital; Department of Medicine (C.H.T.L.), Queen Elizabeth Hospital, Hong Kong, China; Departments of Medicine and Neurology (P.K.), The University of Melbourne, Royal Melbourne Hospital, Australia; Department of Epidemiology and Preventive Medicine (S.S.C.) and Department of Anatomy and Anthropology (S.S.C.), Sackler Faculty of Medicine, Tel Aviv University, Israel; and The State Key Laboratory of Brain and Cognitive Sciences (P.C.S., S.S.C.).

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http://dx.doi.org/10.1212/NXG.0000000000000245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999346PMC
June 2018

Rapid, Loop-Mediated Isothermal Amplification Detection of Celiac Disease Risk Alleles.

J Mol Diagn 2018 05 17;20(3):307-315. Epub 2018 Feb 17.

Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia; Department of Electrical and Electronic Engineering, University of Melbourne, Melbourne, Victoria, Australia; Department of Neurology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2018.01.005DOI Listing
May 2018

Association between different acute stroke therapies and development of post stroke seizures.

BMC Neurol 2018 May 3;18(1):61. Epub 2018 May 3.

Melbourne Brain Centre, Royal Melbourne Hospital and Department of Neurology, University of Melbourne, Parkville, Melbourne, Australia.

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http://dx.doi.org/10.1186/s12883-018-1064-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5932812PMC
May 2018

Neurologist-patient communication about epilepsy in the United States, Spain, and Germany.

Neurol Clin Pract 2018 Apr;8(2):93-101

David Geffen School of Medicine (JMS), University of California Los Angeles; University of Campinas (UNICAMP) and the Brazilian Institute of Neuroscience and Neurotechnology (BRAINN) (FC), Campinas, São Paulo, Brazil; University of Kentucky Epilepsy Center (EpiC) (FG), Lexington; University of Melbourne (PK), Parkville, Australia; Centre Hospitalier Universitaire Vaudois (PR), Lausanne, Switzerland; Mayo Clinic (JS), Scottsdale, AZ; Spectrum Health Medical Group (BS), Grand Rapids, MI; MicroMass Communications, Inc. (AA), Cary, NC; and Verilogue, Inc. (LW), Horsham, PA.

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http://dx.doi.org/10.1212/CPJ.0000000000000442DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5914745PMC
April 2018

Association between implementation of a code stroke system and poststroke epilepsy.

Neurology 2018 03 21;90(13):e1126-e1133. Epub 2018 Feb 21.

From the Department of Neurology, Melbourne Brain Centre, Royal Melbourne Hospital (Ziyi Chen, Ziyuan Chen, J.N., M.K., B.Y., P.K.), and Florey Institute of Neuroscience and Mental Health, Austin Health (L.C.), The University of Melbourne, Australia; and Department of Neurology (Ziyi Chen), The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005212DOI Listing
March 2018

Association between hemorrhagic transformation after endovascular therapy and poststroke seizures.

Epilepsia 2018 02 30;59(2):403-409. Epub 2017 Dec 30.

Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, Vic., Australia.

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http://doi.wiley.com/10.1111/epi.13982
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http://dx.doi.org/10.1111/epi.13982DOI Listing
February 2018

Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study.

Brain 2018 02;141(2):391-408

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK.

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https://academic.oup.com/brain/article/141/2/391/4818311
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http://dx.doi.org/10.1093/brain/awx341DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5837616PMC
February 2018

Post-Stroke Seizures Is Associated with Low Alberta Stroke Program Early CT Score.

Cerebrovasc Dis 2017 4;43(5-6):259-265. Epub 2017 Mar 4.

Melbourne Brain Centre, The Royal Melbourne Hospital, Department of Medicine, Parkville, VIC, Australia.

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http://dx.doi.org/10.1159/000458449DOI Listing
January 2018

Genetic overlap between epilepsy and schizophrenia: Evidence from cross phenotype analysis in Hong Kong Chinese population.

Am J Med Genet B Neuropsychiatr Genet 2018 Jan 17;177(1):86-92. Epub 2017 Nov 17.

Center for Genomic Sciences, The University of Hong Kong, Hong Kong, SAR, China.

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http://dx.doi.org/10.1002/ajmg.b.32607DOI Listing
January 2018

IDH1 and IDH2 mutations in postoperative diffuse glioma-associated epilepsy.

Epilepsy Behav 2018 01 22;78:30-36. Epub 2017 Dec 22.

Department of Surgery, The University of Melbourne, Parkville, Australia; Department of Neurosurgery, Royal Melbourne Hospital, Parkville, Australia.

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http://dx.doi.org/10.1016/j.yebeh.2017.10.027DOI Listing
January 2018

Evaluation of perampanel as monotherapy for focal seizures: Experience from open-label extension studies.

Epilepsy Behav Case Rep 2018 1;9:1-5. Epub 2017 Dec 1.

Formerly: Eisai Ltd., Hatfield, Hertfordshire, AL10 9SN, UK.

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http://dx.doi.org/10.1016/j.ebcr.2017.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916525PMC
December 2017

Incidence of sudden unexpected death in epilepsy in community-based cohort in China.

Epilepsy Behav 2017 11 27;76:76-83. Epub 2017 Sep 27.

NIHR University College London Hospitals Biomedical Research Centre, UCL Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom; Chalfont Centre for Epilepsy, Chalfont St Peter SL9 0RJ, United Kingdom; Stichting Epilepsie Instellingen Nederland (SEIN), Achterweg 5, Heemstede 2103 SW, The Netherlands; UCL Institute of Neurology, Box 29, 33 Queen Square, London WC1N 3BG, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2017.08.024DOI Listing
November 2017

Accelerated kindling epileptogenesis in Tg4510 tau transgenic mice, but not in tau knockout mice.

Epilepsia 2017 09 15;58(9):e136-e141. Epub 2017 Jul 15.

Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.13847DOI Listing
September 2017

Association between switching antiepileptic drug products and healthcare utilization: A systematic review.

Epilepsy Behav 2017 08 20;73:166-172. Epub 2017 Jun 20.

Faculty of Medicine, Neurology Service & Porto Alegre Epilepsy Surgery Program, Hospital São Lucas, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS), Porto Alegre, Brazil. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15255050173007
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http://dx.doi.org/10.1016/j.yebeh.2017.05.010DOI Listing
August 2017

Familial mesial temporal lobe epilepsy and the borderland of déjà vu.

Ann Neurol 2017 Aug 19;82(2):166-176. Epub 2017 Jul 19.

Epilepsy Research Centre, Department of Medicine, Austin Health, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/ana.24984DOI Listing
August 2017

Understanding the burden of focal epilepsy as a function of seizure frequency in the United States, Europe, and Brazil.

Epilepsia Open 2017 06 27;2(2):199-213. Epub 2017 Mar 27.

The University of Melbourne and Royal Melbourne Hospital Parkville Victoria Australia.

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http://dx.doi.org/10.1002/epi4.12050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719850PMC
June 2017

Impact of Drug Manipulation on Seizure Freedom in Adults with Uncontrolled Epilepsy: A Prospective Controlled Study in Rural China.

CNS Drugs 2017 Mar;31(3):237-243

Department of Neurology, West China Hospital, Sichuan University, Chengdu, Sichuan, 610000, China.

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http://link.springer.com/10.1007/s40263-016-0397-5
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http://dx.doi.org/10.1007/s40263-016-0397-5DOI Listing
March 2017

Real-world utility of whole exome sequencing with targeted gene analysis for focal epilepsy.

Epilepsy Res 2017 03 7;131:1-8. Epub 2017 Feb 7.

Departments of Medicine and Neurology, The Royal Melbourne Hospital, The University of Melbourne, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1016/j.eplepsyres.2017.02.001DOI Listing
March 2017

Drug development for refractory epilepsy: The past 25 years and beyond.

Seizure 2017 Jan 6;44:147-156. Epub 2016 Dec 6.

Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville, Australia; Department of Neurology, Royal Melbourne Hospital, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.seizure.2016.11.022DOI Listing
January 2017

Cathodal transcranial direct-current stimulation for treatment of drug-resistant temporal lobe epilepsy: A pilot randomized controlled trial.

Epilepsia Open 2016 12 17;1(3-4):130-135. Epub 2016 Oct 17.

School of Primary Health Care Faculty of Medicine, Nursing and Health Sciences Monash University Frankston Victoria Australia.

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http://dx.doi.org/10.1002/epi4.12020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719830PMC
December 2016

Postoperative seizure control in patients with tumor-associated epilepsy.

Epilepsia 2016 11 26;57(11):1779-1788. Epub 2016 Sep 26.

Department of Medicine, The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.13562DOI Listing
November 2016

Contribution of GABRG2 Polymorphisms to Risk of Epilepsy and Febrile Seizure: a Multicenter Cohort Study and Meta-analysis.

Mol Neurobiol 2016 10 9;53(8):5457-67. Epub 2015 Oct 9.

Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Lembah Pantai, 59100, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s12035-015-9457-yDOI Listing
October 2016

Psychotic disorders induced by antiepileptic drugs in people with epilepsy.

Brain 2016 Oct 8;139(Pt 10):2668-2678. Epub 2016 Aug 8.

1 Departments of Medicine and Neurology, The Melbourne Brain Centre, The University of Melbourne, The Royal Melbourne Hospital, Victoria, Australia

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
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http://dx.doi.org/10.1093/brain/aww196DOI Listing
October 2016

White Matter Hyperintensities on Brain Magnetic Resonance Imaging in People with Epilepsy: A Hospital-Based Study.

CNS Neurosci Ther 2016 09 6;22(9):758-63. Epub 2016 Jun 6.

Melbourne Brain Centre, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Vic, Australia.

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http://dx.doi.org/10.1111/cns.12571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492825PMC
September 2016

Peritumoural glutamate correlates with post-operative seizures in supratentorial gliomas.

J Neurooncol 2016 09 16;129(2):259-67. Epub 2016 Jun 16.

Department of Neurosurgery, Royal Melbourne Hospital, University of Melbourne, 3050, Parkville, VIC, Australia.

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September 2016

Efficacy and safety of retigabine/ezogabine as adjunctive therapy in adult Asian patients with drug-resistant partial-onset seizures: A randomized, placebo-controlled Phase III study.

Epilepsy Behav 2016 08 1;61:224-230. Epub 2016 Jul 1.

Departments of Medicine and Neurology, University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2016.05.018DOI Listing
August 2016

Excess mortality and hospitalized morbidity in newly treated epilepsy patients.

Neurology 2016 Aug 15;87(7):718-25. Epub 2016 Jul 15.

From the Department of Medicine (Z.C., D.L., P.K.), The University of Melbourne; Melbourne Brain Centre (Z.C., D.L.), Melbourne EpiCentre (D.L.), and Department of Neurology (P.K.), Royal Melbourne Hospital, Parkville, Australia; and Department of Medicine and Therapeutics (P.K.), Chinese University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1212/WNL.0000000000002984DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999164PMC
August 2016

Association of BDNF Polymorphisms with the Risk of Epilepsy: a Multicenter Study.

Mol Neurobiol 2016 07 16;53(5):2869-2877. Epub 2015 Apr 16.

Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Lembah Pantai, 59100, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s12035-015-9150-1DOI Listing
July 2016

Safety, tolerability, and seizure control during long-term treatment with adjunctive brivaracetam for partial-onset seizures.

Epilepsia 2016 07 6;57(7):1139-51. Epub 2016 Jun 6.

University of Melbourne and Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.13416DOI Listing
July 2016

Point-of-care molecular diagnostic devices: an overview.

Pharmacogenomics 2015 31;16(12):1399-409. Epub 2015 Jul 31.

Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Parkville, VIC 3050, Australia.

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https://www.futuremedicine.com/doi/10.2217/pgs.15.92
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http://dx.doi.org/10.2217/pgs.15.92DOI Listing
June 2016

Computed tomography perfusion as a diagnostic tool for seizures after ischemic stroke.

Neuroradiology 2016 Jun 9;58(6):577-584. Epub 2016 Mar 9.

Melbourne Brain Centre, The Royal Melbourne Hospital, Parkville, VIC, 3050, Australia.

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http://dx.doi.org/10.1007/s00234-016-1670-5DOI Listing
June 2016

The Effects of Cathodal Transcranial Direct Current Stimulation in a Patient with Drug-Resistant Temporal Lobe Epilepsy (Case Study).

Brain Stimul 2016 Sep-Oct;9(5):790-792. Epub 2016 Jun 1.

School of Primary Health Care, Faculty of Medicine, Nursing and Health Sciences, Monash University, Australia.

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http://dx.doi.org/10.1016/j.brs.2016.05.011DOI Listing
June 2016

Real-world cost-effectiveness of pharmacogenetic screening for epilepsy treatment.

Neurology 2016 Mar 17;86(12):1086-94. Epub 2016 Feb 17.

From the Department of Medicine (Z.C., D.L., P.K.), The University of Melbourne, Parkville; Melbourne Brain Centre (Z.C., D.L.), Melbourne EpiCentre (D.L.), and Department of Neurology (P.K.), Royal Melbourne Hospital, Parkville, Australia; and Department of Medicine and Therapeutics (P.K.), Chinese University of Hong Kong, China.

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http://dx.doi.org/10.1212/WNL.0000000000002484DOI Listing
March 2016

Understanding the burden of idiopathic generalized epilepsy in the United States, Europe, and Brazil: An analysis from the National Health and Wellness Survey.

Epilepsy Behav 2016 Feb 14;55:146-56. Epub 2016 Jan 14.

Centre Hospitalier Universitaire Vaudois, Département des Neurosciences Cliniques, BH/10/137 Rue du Bugnon 46, CH-1011 Lausanne, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2015.12.018DOI Listing
February 2016

The [NiFe]-Hydrogenase of Pyrococcus furiosus Exhibits a New Type of Oxygen Tolerance.

J Am Chem Soc 2015 Oct 16;137(42):13556-65. Epub 2015 Oct 16.

Department of Chemistry and Biochemistry, Arizona State University , Tempe, Arizona 85287, United States.

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http://dx.doi.org/10.1021/jacs.5b07680DOI Listing
October 2015

Mindfulness-based therapy for drug-resistant epilepsy: An assessor-blinded randomized trial.

Neurology 2015 Sep 2;85(13):1100-7. Epub 2015 Sep 2.

From the Department of Clinical Psychology (V.T.), the Division of Neurosurgery, Department of Surgery, Faculty of Medicine (V.T., W.S.P.), and the Division of Neurology, Department of Medicine and Therapeutics, Faculty of Medicine (P.K.), Prince of Wales Hospital, The Chinese University of Hong Kong; and the Departments of Medicine and Neurology (P.K.), The University of Melbourne, Royal Melbourne Hospital, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000001967DOI Listing
September 2015

Real-world efficiency of pharmacogenetic screening for carbamazepine-induced severe cutaneous adverse reactions.

PLoS One 2014 7;9(5):e96990. Epub 2014 May 7.

Department of Medicine, The University of Melbourne, Parkville, Australia; Department of Neurology, Royal Melbourne Hospital, Parkville, Australia; Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013087PMC
June 2015

A mouse model of Alzheimer's disease displays increased susceptibility to kindling and seizure-associated death.

Epilepsia 2015 Jun 16;56(6):e73-7. Epub 2015 Apr 16.

Department of Medicine (RMH), The University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.12993DOI Listing
June 2015

Research priorities in epilepsy for the Asia-Oceanian region.

Epilepsia 2015 May 30;56(5):667-73. Epub 2015 Mar 30.

Department of Psychiatry, National Center of Neurology and Psychiatry, Tokyo, Japan.

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http://dx.doi.org/10.1111/epi.12957DOI Listing
May 2015

Magnetic resonance imaging in adults with epilepsy: a pictorial essay.

J Med Imaging Radiat Oncol 2014 16;58(3):312-9. Epub 2014 Jan 16.

Department of Radiology, The Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/1754-9485.12150DOI Listing
April 2015

Mortality in epilepsy: questions beyond death.

Neurology 2014 Nov 22;83(21):1886-7. Epub 2014 Oct 22.

From the Departments of Medicine and Neurology (P.K.), The University of Melbourne, Royal Melbourne Hospital, Parkville, Victoria, Australia; and the Division of Neurology (D.D.), The Children's Hospital of Philadelphia, PA.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000100
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November 2014

Effects of a HLA-B*15:02 screening policy on antiepileptic drug use and severe skin reactions.

Neurology 2014 Nov 29;83(22):2077-84. Epub 2014 Oct 29.

From the Department of Medicine (Z.C., D.L., P.K.), The University of Melbourne, Parkville; Melbourne Brain Centre (Z.C., D.L.), Melbourne EpiCentre (D.L.), and Department of Neurology (P.K.), Royal Melbourne Hospital, Parkville, Australia; and Department of Medicine and Therapeutics (P.K.), Chinese University of Hong Kong, Prince of Wales Hospital, China.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000103
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http://dx.doi.org/10.1212/WNL.0000000000001034DOI Listing
November 2014

Multilocus sequence typing confirms wild birds as the source of a Campylobacter outbreak associated with the consumption of raw peas.

Appl Environ Microbiol 2014 Aug;80(15):4540-6

Enteric Diseases Laboratory Branch, Division of Foodborne, Waterborne and Environmental Diseases, National Center for Emerging and Zoonotic Infectious Diseases

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http://dx.doi.org/10.1128/AEM.00537-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4148789PMC
August 2014

Psychobehavioral therapy for epilepsy.

Epilepsy Behav 2014 Mar 10;32:147-55. Epub 2014 Jan 10.

Departments of Medicine and Neurology, The University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia; Division of Neurology, Department of Medicine and Therapeutics, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1016/j.yebeh.2013.12.004DOI Listing
March 2014

In vitro transport assays of rufinamide, pregabalin, and zonisamide by human P-glycoprotein.

Epilepsy Res 2014 Mar 30;108(3):359-66. Epub 2014 Jan 30.

School of Pharmacy, The Chinese University of Hong Kong, Shatin, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.eplepsyres.2014.01.011DOI Listing
March 2014

Perampanel for adjunctive treatment of partial-onset seizures: a pooled dose-response analysis of phase III studies.

Epilepsia 2014 Mar 7;55(3):423-31. Epub 2014 Mar 7.

Eisai Neuroscience and General Medicine Product Creation Unit, Eisai Inc, Woodcliff Lake, New Jersey, U.S.A.

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http://doi.wiley.com/10.1111/epi.12527
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March 2014

ABCC2 rs2273697 and rs3740066 polymorphisms and resistance to antiepileptic drugs in Asia Pacific epilepsy cohorts.

Pharmacogenomics 2014 Mar;15(4):459-66

Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.2217/pgs.13.239DOI Listing
March 2014

Febrile seizure recurrence reduced by intermittent oral levetiracetam.

Ann Clin Transl Neurol 2014 Mar 24;1(3):171-9. Epub 2014 Feb 24.

Departments of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne Melbourne, Australia ; Department of Medicine and Therapeutics, Chinese University of Hong Kong Hong Kong, China.

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http://dx.doi.org/10.1002/acn3.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184546PMC
March 2014

Pregabalin monotherapy in patients with partial-onset seizures: a historical-controlled trial.

Neurology 2014 02 10;82(7):590-7. Epub 2014 Jan 10.

From the NYU Comprehensive Epilepsy Center (J.F.), New York, NY; Departments of Medicine and Neurology (P.K.), University of Melbourne, Royal Melbourne Hospital, Australia; Department of Medicine and Therapeutics (P.K.), Chinese University of Hong Kong, China; St. Joseph Health System (T.F.), Lexington, KY; and Pfizer Inc. (V.P., S.D., L.K., L.Y.), New York, NY.

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http://dx.doi.org/10.1212/WNL.0000000000000119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3963419PMC
February 2014

Adjunctive brivaracetam for uncontrolled focal and generalized epilepsies: results of a phase III, double-blind, randomized, placebo-controlled, flexible-dose trial.

Epilepsia 2014 Jan 3;55(1):38-46. Epub 2013 Oct 3.

Division of Neurology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; Departments of Medicine and Neurology, The University of Melbourne, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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http://doi.wiley.com/10.1111/epi.12391
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http://dx.doi.org/10.1111/epi.12391DOI Listing
January 2014

Neurocognitive and psychological profiles of adult patients with epilepsy in Hong Kong.

Epilepsy Behav 2013 Nov 4;29(2):337-43. Epub 2013 Sep 4.

Department of Clinical Psychology, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region; Division of Neurosurgery, Department of Surgery, Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region. Electronic address:

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http://dx.doi.org/10.1016/j.yebeh.2013.07.027DOI Listing
November 2013

The potential role of CAMSAP1L1 in symptomatic epilepsy.

Neurosci Lett 2013 Nov 20;556:146-51. Epub 2013 Oct 20.

School of Pharmacy, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

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http://dx.doi.org/10.1016/j.neulet.2013.10.020DOI Listing
November 2013