Patrick F H Lai

Patrick F H Lai

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Patrick F H Lai

Patrick F H Lai

Publications by authors named "Patrick F H Lai"

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19Publications

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Essential role of ryanodine receptor 2 phosphorylation in the effect of azumolene on ventricular arrhythmia vulnerability in a rabbit heart model.

J Cardiovasc Electrophysiol 2018 12 31;29(12):1707-1715. Epub 2018 Oct 31.

The Hull Family Cardiac Fibrillation Management Laboratory, Division of Cardiology, Toronto General Hospital, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1111/jce.13737
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http://dx.doi.org/10.1111/jce.13737DOI Listing
December 2018

Resolving Bipolar Electrogram Voltages During Atrial Fibrillation Using Omnipolar Mapping.

Circ Arrhythm Electrophysiol 2017 Sep;10(9)

From the The Hull Family Cardiac Fibrillation Management Laboratory (S.K.H., K.M., A.P.-S., S.M., P.F.H.L., M.A.A., J.A., M.K., A.C.T.H., V.C., K.N.) and Toronto Health Economics and Technology Assessment Collaborative (N.M.), Toronto General Hospital, University Health Network, Ontario, Canada; St. Michael's Hospital, Toronto, Ontario, Canada (P.D.); and Abbott Laboratories, St. Paul, MN (D.C.D.).

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http://dx.doi.org/10.1161/CIRCEP.117.005018DOI Listing
September 2017

Physiological Assessment of Ventricular Myocardial Voltage Using Omnipolar Electrograms.

J Am Heart Assoc 2017 Aug 16;6(8). Epub 2017 Aug 16.

The Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada

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http://dx.doi.org/10.1161/JAHA.117.006447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586472PMC
August 2017

Effects of Renal Artery Denervation on Ventricular Arrhythmias in a Postinfarct Model.

Circ Cardiovasc Interv 2017 Mar;10(3):e004172

From the Hull Family Cardiac Fibrillation Management Laboratory, Division of Cardiology (N.J., S.G., M.A.A., B.K., N.Z., A.P.-S., M.K., S.M., P.F.H.L., G.K.K.N., K.N.) and Department of Pathology (R.J., T.-R.K.), University Health Network, Toronto, Ontario, Canada; St Michael's Hospital, Toronto, Ontario, Canada (A.R., A.A.-H., J.G., P.D.); University of Newcastle, Australia (N.J.); and Mount Sinai Hospital, Toronto, Ontario, Canada (J.P.).

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http://dx.doi.org/10.1161/CIRCINTERVENTIONS.116.004172DOI Listing
March 2017

Effects of Late Sodium Current Blockade on Ventricular Refibrillation in a Rabbit Model.

Circ Arrhythm Electrophysiol 2017 Mar;10(3)

From the Hull Family Cardiac Fibrillation Management Laboratory, Toronto General Hospital, University Health Network, Ontario, Canada (M.A.A., N.Z., S.M., M.K., P.F.H.L., G.K.N., N.S.T., K.N.); and Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (C.L.).

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http://dx.doi.org/10.1161/CIRCEP.116.004331DOI Listing
March 2017

The need for and the challenges of measuring renal sympathetic nerve activity.

Heart Rhythm 2016 05 19;13(5):1166-1171. Epub 2016 Jan 19.

University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2016.01.018DOI Listing
May 2016

Feature-based MRI data fusion for cardiac arrhythmia studies.

Comput Biol Med 2016 May 19;72:13-21. Epub 2016 Feb 19.

Department of Electrical and Computer Engineering, Ryerson University, 350 Victoria Street, Toronto, Ontario, Canada M5B2K3.

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http://dx.doi.org/10.1016/j.compbiomed.2016.02.006DOI Listing
May 2016

Feeding the fibrillating heart: Dichloroacetate improves cardiac contractile dysfunction following VF.

Am J Physiol Heart Circ Physiol 2015 Nov 4;309(9):H1543-53. Epub 2015 Sep 4.

The Hull Family Cardiac Fibrillation Management Laboratory, University Health Network, Toronto, Ontario, Canada;

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http://dx.doi.org/10.1152/ajpheart.00404.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666969PMC
November 2015

Dantrolene improves survival after ventricular fibrillation by mitigating impaired calcium handling in animal models.

Circulation 2014 Feb 8;129(8):875-85. Epub 2014 Jan 8.

From The Hull Family Cardiac Fibrillation Management Laboratory, University Health Network, University of Toronto, Toronto, ON, Canada (A.M., N.Z., S.M., M.K., M.A.A, P.F.H.L., M.B.W., K.N.); Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, ON, Canada (A.R., X.H., A.A.-H., P.D.); Institute of Medical Science, University of Toronto, Toronto, ON, Canada (N.Z.); Department of Physiology, University of Toronto, Toronto, ON, Canada (J.L., P.B.); Institute LIRYC, Université Bordeaux 1, Bordeaux, France (E.J.V.); Institute for Computational Medicine, Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD (P.M.B.); and Department of Electrical Engineering, University of Calgary, Calgary, AB, Canada (E.B.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005443DOI Listing
February 2014

Mesenchymal stem cell transplantation mitigates electrophysiological remodeling in a rat model of myocardial infarction.

J Cardiovasc Electrophysiol 2013 Jul 3;24(7):813-21. Epub 2013 May 3.

The Hull Family Cardiac Fibrillation Management Laboratory, Division of Cardiology, Toronto General Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/jce.12162DOI Listing
July 2013

Mesenchymal stem cells reduce inflammation while enhancing bacterial clearance and improving survival in sepsis.

Am J Respir Crit Care Med 2010 Oct 17;182(8):1047-57. Epub 2010 Jun 17.

The Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ontario, Canada, K1H 8L6.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201001-0010O
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http://dx.doi.org/10.1164/rccm.201001-0010OCDOI Listing
October 2010

Tyrosine phosphatase beta regulates angiopoietin-Tie2 signaling in human endothelial cells.

Angiogenesis 2009 1;12(1):25-33. Epub 2009 Jan 1.

Terrence Donnelly Heart Centre and Division of Cardiology, St Michael's Hospital, 30 Bond Street, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s10456-008-9126-0DOI Listing
June 2009

Cell-based angiopoietin-1 gene therapy for acute lung injury.

Am J Respir Crit Care Med 2007 May 22;175(10):1014-26. Epub 2007 Feb 22.

St. Michael's Hospital, Toronto, ON, M5B 1W8, Canada.

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http://dx.doi.org/10.1164/rccm.200609-1370OCDOI Listing
May 2007

Regulation of endothelin-1 by angiopoietin-1: implications for inflammation.

Exp Biol Med (Maywood) 2006 Jun;231(6):985-91

Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michae's Hospital, Toronto, Ontario, Canada.

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June 2006

Downregulation of eNOS mRNA expression by TNFalpha: identification and functional characterization of RNA-protein interactions in the 3'UTR.

Cardiovasc Res 2003 Jul;59(1):160-8

The Terrence Donnelly Research Laboratories, Division of Cardiology, St. Michael's Hospital, and Institute of Medical Science, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/s0008-6363(03)00296-7DOI Listing
July 2003