Patrick Calsou

Patrick Calsou

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Patrick Calsou

Patrick Calsou

Publications by authors named "Patrick Calsou"

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CNBP controls transcription by unfolding DNA G-quadruplex structures.

Nucleic Acids Res 2019 Sep;47(15):7901-7913

Instituto de Biología Molecular y Celular de Rosario (IBR), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) - Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Ocampo y Esmeralda, S2000EZP, Rosario, Argentina.

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http://dx.doi.org/10.1093/nar/gkz527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6735679PMC
September 2019

G-Quadruplex binding optimization by gold(iii) insertion into the center of a porphyrin.

Dalton Trans 2019 May;48(18):6091-6099

Institut de Pharmacologie et Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.

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http://xlink.rsc.org/?DOI=C8DT04703K
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http://dx.doi.org/10.1039/c8dt04703kDOI Listing
May 2019

Plugged into the Ku-DNA hub: The NHEJ network.

Prog Biophys Mol Biol 2019 Mar 6. Epub 2019 Mar 6.

Institut de Pharmacologie et Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France; Equipe Labellisée Ligue Contre le Cancer, Toulouse, France. Electronic address:

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http://dx.doi.org/10.1016/j.pbiomolbio.2019.03.001DOI Listing
March 2019

Alkyne-Tagged Analogue of Jaspine B: New Tool for Identifying Jaspine B Mode of Action.

Chembiochem 2018 12 7;19(23):2438-2442. Epub 2018 Nov 7.

SPCMIB, UMR5068 CNRS-Université Paul Sabatier-Toulouse III, 118 route de Narbonne, 31062, Toulouse, France.

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http://doi.wiley.com/10.1002/cbic.201800496
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http://dx.doi.org/10.1002/cbic.201800496DOI Listing
December 2018

The DNA-Binding Polyamine Moiety in the Vectorized DNA Topoisomerase II Inhibitor F14512 Alters Reparability of the Consequent Enzyme-Linked DNA Double-Strand Breaks.

Mol Cancer Ther 2017 10 13;16(10):2166-2177. Epub 2017 Jun 13.

Institut de Pharmacologie et Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-16-0767DOI Listing
October 2017

Coordinated nuclease activities counteract Ku at single-ended DNA double-strand breaks.

Nat Commun 2016 09 19;7:12889. Epub 2016 Sep 19.

Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, 31077 Toulouse, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031800PMC
http://dx.doi.org/10.1038/ncomms12889DOI Listing
September 2016

Structure-Based Virtual Ligand Screening on the XRCC4/DNA Ligase IV Interface.

Sci Rep 2016 Mar 11;6:22878. Epub 2016 Mar 11.

Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, CNRS, UPS, France.

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http://dx.doi.org/10.1038/srep22878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4786802PMC
March 2016

Single-stranded DNA oligomers stimulate error-prone alternative repair of DNA double-strand breaks through hijacking Ku protein.

Nucleic Acids Res 2015 Dec 8;43(21):10264-76. Epub 2015 Sep 8.

CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), BP 64182, 205 route de Narbonne, F-31077 Toulouse, Cedex4, France Université de Toulouse, UPS, IPBS, F-31077 Toulouse, France Equipe labellisée Ligue Nationale Contre le Cancer, France

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http://nar.oxfordjournals.org/content/early/2015/09/07/nar.g
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkv894
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http://dx.doi.org/10.1093/nar/gkv894DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4666393PMC
December 2015

The nickel(II) complex of guanidinium phenyl porphyrin, a specific G-quadruplex ligand, targets telomeres and leads to POT1 mislocalization in culture cells.

J Biol Inorg Chem 2015 Jun 7;20(4):729-38. Epub 2015 Apr 7.

Centre National de la Recherche Scientifique, Laboratoire de Chimie de Coordination, 205 Route de Narbonne, 31077, Toulouse, France.

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http://dx.doi.org/10.1007/s00775-015-1260-8DOI Listing
June 2015

Neddylation promotes ubiquitylation and release of Ku from DNA-damage sites.

Cell Rep 2015 May 23;11(5):704-14. Epub 2015 Apr 23.

The Wellcome Trust and Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge 2 1QN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.03.058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4431666PMC
May 2015

Loss of BRCA1 impairs centromeric cohesion and triggers chromosomal instability.

FASEB J 2014 Dec 9;28(12):5250-61. Epub 2014 Sep 9.

Institute of Pharmacology and Structural Biology, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 5089, Toulouse, France; University of Toulouse, Université Paul Sabatier, Toulouse, France; and

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http://dx.doi.org/10.1096/fj.14-250266DOI Listing
December 2014

DNA damage triggers SAF-A and RNA biogenesis factors exclusion from chromatin coupled to R-loops removal.

Nucleic Acids Res 2014 Aug 16;42(14):9047-62. Epub 2014 Jul 16.

CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), BP 64182, 205 route de Narbonne, F-31077 Toulouse, Cedex 4, France Université de Toulouse, UPS, IPBS, F-31077 Toulouse, France Equipe Labellisée Ligue Nationale Contre le Cancer

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http://dx.doi.org/10.1093/nar/gku601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132723PMC
August 2014

Alternative end-joining pathway(s): bricolage at DNA breaks.

DNA Repair (Amst) 2014 May 6;17:81-97. Epub 2014 Mar 6.

CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), BP 64182, 205 route de Narbonne, 31077 Toulouse, Cedex4, France; Université de Toulouse, UPS, IPBS, F-31077 Toulouse, France; Equipe labellisée Ligue Nationale Contre le Cancer, France. Electronic address:

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http://dx.doi.org/10.1016/j.dnarep.2014.02.007DOI Listing
May 2014

Role of intercalation and redox potential in DNA photosensitization by ruthenium(II) polypyridyl complexes: assessment using DNA repair protein tests.

Photochem Photobiol Sci 2013 Aug;12(8):1517-26

Université de Toulouse, Laboratoire des IMRCP, UMR 5623 CNRS, 118 Route de Narbonne, F-31062 Toulouse Cedex 9, France.

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http://dx.doi.org/10.1039/c3pp50070eDOI Listing
August 2013

A noncatalytic function of the ligation complex during nonhomologous end joining.

J Cell Biol 2013 Jan;200(2):173-86

Centre National de la Recherche Scientifique, Institut de Pharmacologie et de Biologie Structurale, Toulouse F-31077, Cedex 4, France.

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http://dx.doi.org/10.1083/jcb.201203128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3549972PMC
January 2013

Ku counteracts mobilization of PARP1 and MRN in chromatin damaged with DNA double-strand breaks.

Nucleic Acids Res 2011 Dec 31;39(22):9605-19. Epub 2011 Aug 31.

CNRS, Institut de Pharmacologie et de Biologie Structurale, F-31077 Toulouse, France.

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http://dx.doi.org/10.1093/nar/gkr656DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3239177PMC
December 2011

Improvement of porphyrins for G-quadruplex DNA targeting.

Biochimie 2011 Aug 17;93(8):1310-7. Epub 2011 Jun 17.

CNRS, Laboratoire de Chimie de Coordination, 205 Route de Narbonne, Toulouse Cedex 4, France.

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http://dx.doi.org/10.1016/j.biochi.2011.06.008DOI Listing
August 2011

A G-quadruplex structure within the 5'-UTR of TRF2 mRNA represses translation in human cells.

Nucleic Acids Res 2010 Nov 22;38(20):7187-98. Epub 2010 Jun 22.

CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), 205 route de Narbonne, 31077 Toulouse, Université de Toulouse, UPS, IPBS, F-31077 Toulouse, France.

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http://dx.doi.org/10.1093/nar/gkq563DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978344PMC
November 2010

Cell nonhomologous end joining capacity controls SAF-A phosphorylation by DNA-PK in response to DNA double-strand breaks inducers.

Cell Cycle 2009 Nov 9;8(22):3717-22. Epub 2009 Nov 9.

CNRS, IPBS (Institut de Pharmacologie et de Biologie Structurale), Toulouse, France; Université de Toulouse, UPS, IPBS, Toulouse, France.

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http://dx.doi.org/10.4161/cc.8.22.10025DOI Listing
November 2009

ARTEMIS nuclease facilitates apoptotic chromatin cleavage.

Cancer Res 2009 Oct 6;69(20):8120-6. Epub 2009 Oct 6.

CNRS, Institut de Pharmacologie et de Biologie Structurale, Université de Toulouse, UPS, Institut de Pharmacologie et de Biologie Structurale, Toulouse, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4400DOI Listing
October 2009

Effect of double-strand break DNA sequence on the PARP-1 NHEJ pathway.

Biochem Biophys Res Commun 2008 May 3;369(3):982-8. Epub 2007 Dec 3.

Institut de Pharmacologie et de Biologie Structurale, CNRS UMR5089, 205 route de Narbonne, F-31077 Toulouse, Cedex, France.

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http://dx.doi.org/10.1016/j.bbrc.2007.11.132DOI Listing
May 2008

c-MYC protein is degraded in response to UV irradiation.

Cell Cycle 2008 Jan 2;7(1):63-70. Epub 2007 Oct 2.

Institut de Pharmacologie et de Biologie Structurale, CNRS-Université de Toulouse, Toulouse, France.

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http://dx.doi.org/10.4161/cc.7.1.5111DOI Listing
January 2008

Interplay between Cernunnos-XLF and nonhomologous end-joining proteins at DNA ends in the cell.

J Biol Chem 2007 Nov 24;282(44):31937-43. Epub 2007 Aug 24.

Institut de Pharmacologie et de Biologie Structurale, CNRS-Université de Toulouse, UMR 5089, Toulouse, and INSERM, Hôpital Necker-Enfants Malades, U768, Unité Développement Normal et Pathologique du Système Immunitaire, F-75015 Paris, France.

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http://dx.doi.org/10.1074/jbc.M704554200DOI Listing
November 2007

Long-term XPC silencing reduces DNA double-strand break repair.

Cancer Res 2007 Mar;67(6):2526-34

Commissariat à l'Energie Atomique, Laboratoire de Génétique de la Radiosensibilité, Département de Radiobiologie et de Radiopathologie, Direction des Sciences du Vivant, Fontenay-aux-Roses, France.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-3371DOI Listing
March 2007

Interplay between Ku, Artemis, and the DNA-dependent protein kinase catalytic subunit at DNA ends.

J Biol Chem 2006 Sep 19;281(38):27784-93. Epub 2006 Jul 19.

Institut de Pharmacologie et de Biologie Structurale, CNRS UMR 5089, 205 Route de Narbonne, 31077 Toulouse, Cedex 4, France.

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http://dx.doi.org/10.1074/jbc.M603047200DOI Listing
September 2006

Involvement of polynucleotide kinase in a poly(ADP-ribose) polymerase-1-dependent DNA double-strand breaks rejoining pathway.

J Mol Biol 2006 Feb 28;356(2):257-65. Epub 2005 Nov 28.

Institut de Pharmacologie et de Biologie Structurale, CNRS UMR 5089, Toulouse, France.

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http://dx.doi.org/10.1016/j.jmb.2005.11.028DOI Listing
February 2006

DNA-dependent protein kinase and XRCC4-DNA ligase IV mobilization in the cell in response to DNA double strand breaks.

J Biol Chem 2005 Feb 31;280(8):7060-9. Epub 2004 Oct 31.

Institut de Pharmacologie et de Biologie Structurale, CNRS UMR 5089, 205 route de Narbonne, 31077 Toulouse, Cedex 4, France.

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http://dx.doi.org/10.1074/jbc.M410746200DOI Listing
February 2005

Involvement of poly(ADP-ribose) polymerase-1 and XRCC1/DNA ligase III in an alternative route for DNA double-strand breaks rejoining.

J Biol Chem 2004 Dec 21;279(53):55117-26. Epub 2004 Oct 21.

Institut de Pharmacologie et de Biologie Structurale, CNRS UMR 5089, 205 route de Narbonne, F-31077 Toulouse Cedex, France.

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http://dx.doi.org/10.1074/jbc.M404524200DOI Listing
December 2004

Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processing.

Nucleic Acids Res 2003 Nov;31(21):6272-82

Centre National de la Recherche Scientifique, Unité Mixte de Recherche 8126, Institut Gustave Roussy, 39 Rue Camille Desmoulins, 94805 Villejuif Cedex, France.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC275476PMC
http://dx.doi.org/10.1093/nar/gkg834DOI Listing
November 2003

Long-patch DNA repair synthesis during base excision repair in mammalian cells.

EMBO Rep 2003 Apr;4(4):363-7

Institut de Pharmacologie et Ciologie Structurale, CNRS UMR, Toulouse, France.

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http://dx.doi.org/10.1038/sj.embor.embor796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1319152PMC
April 2003

Coordinated assembly of Ku and p460 subunits of the DNA-dependent protein kinase on DNA ends is necessary for XRCC4-ligase IV recruitment.

J Mol Biol 2003 Feb;326(1):93-103

Institut de Pharmacologie et de Biologie Structurale, CNRS UMR 5089, 205 route de Narbonne, 31077, Cedex 4, Toulouse, France.

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http://dx.doi.org/10.1016/s0022-2836(02)01328-1DOI Listing
February 2003