Patrick Blanco

Patrick Blanco

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Patrick Blanco

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The Innate Part of the Adaptive Immune System.

Clin Rev Allergy Immunol 2020 Apr;58(2):151-154

UMR1227, Lymphocytes B et Autoimmunité, Univ Brest, Brest, France.

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http://dx.doi.org/10.1007/s12016-019-08740-1DOI Listing
April 2020

Platelets and IgE: Shaping the Innate Immune Response in Systemic Lupus Erythematosus.

Clin Rev Allergy Immunol 2020 Apr;58(2):194-212

Laboratoire d'Immunologie et Immunogénétique, FHU ACRONIM, Hôpital Pellegrin, Centre Hospitalier Universitaire, place Amélie Raba Léon, 33076, Bordeaux, France.

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http://dx.doi.org/10.1007/s12016-019-08744-xDOI Listing
April 2020

Functions of Tfh Cells in Common Variable Immunodeficiency.

Front Immunol 2020 30;11. Epub 2020 Jan 30.

ImmunoConcEpT, CNRS-UMR 5164 and Université de Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.3389/fimmu.2020.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002358PMC
January 2020

HIV protease inhibitors and autoimmunity: An odd, but promising idea.

Autoimmun Rev 2019 Oct 9;18(10):102370. Epub 2019 Aug 9.

Laboratoire d'Immunologie et Immunogénétique, FHU ACRONIM, Hôpital Pellegrin, Centre Hospitalier Universitaire, place Amélie Raba Léon, 33076 Bordeaux, France; Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France; CNRS-UMR 5164, ImmunoConcEpt, Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15689972193017
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http://dx.doi.org/10.1016/j.autrev.2019.102370DOI Listing
October 2019

Prolonged remission in SLE is possible by using reduced doses of prednisone: An observational study from the Lupus-Cruces and Lupus-Bordeaux inception cohorts.

Autoimmun Rev 2019 Sep 16;18(9):102359. Epub 2019 Jul 16.

UMR CNRS5164, ImmunoconcEpT, Bordeaux University, Bordeaux, France; Immunology Department, Pellegrin Hospital, Bordeaux, France; ACRONIM University Hospital Federation, Bordeaux, France.

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http://dx.doi.org/10.1016/j.autrev.2019.102359DOI Listing
September 2019

Increase of follicular helper T cells skewed toward a Th1 profile in CVID patients with non-infectious clinical complications.

Clin Immunol 2018 12 13;197:130-138. Epub 2018 Sep 13.

ImmunoConcEpT, CNRS-UMR 5164, Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.09.006DOI Listing
December 2018

HIBISCUS: Hydroxychloroquine for the secondary prevention of thrombotic and obstetrical events in primary antiphospholipid syndrome.

Autoimmun Rev 2018 Dec 12;17(12):1153-1168. Epub 2018 Oct 12.

Istituto Auxologico Italiano, IRCCS, Laboratory of Immunorheumatology, Milan, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S15689972183022
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http://dx.doi.org/10.1016/j.autrev.2018.05.012DOI Listing
December 2018

Systemic lupus erythematosus and systemic sclerosis: All roads lead to platelets.

Autoimmun Rev 2018 Jun 7;17(6):625-635. Epub 2018 Apr 7.

Laboratoire d'Immunologie et Immunogénétique, FHU ACRONIM, Hôpital Pellegrin, Centre Hospitalier Universitaire, Place Amélie Raba Léon, 33076 Bordeaux, France; Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France; CNRS-UMR 5164, ImmunoConcept, Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2018.01.012DOI Listing
June 2018

IgE in lupus pathogenesis: Friends or foes?

Autoimmun Rev 2018 Apr 7;17(4):361-365. Epub 2018 Feb 7.

ImmunoConcEpT, CNRS-UMR 5164 and Université de Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux, France; Centre Hospitalier Universitaire de Bordeaux, FHU ACRONIM, Place Amélie Raba Léon, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2017.11.027DOI Listing
April 2018

CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases.

Front Immunol 2017 27;8:1216. Epub 2017 Sep 27.

Centre Eugène Marquis, Rennes, France.

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http://dx.doi.org/10.3389/fimmu.2017.01216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623854PMC
September 2017

New Insights on Platelets and Platelet-Derived Microparticles in Systemic Lupus Erythematosus.

Curr Rheumatol Rep 2017 Aug;19(8):48

Université de Bordeaux, 146 rue Léo Saignat, 33076, Bordeaux, France.

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http://dx.doi.org/10.1007/s11926-017-0678-0DOI Listing
August 2017

Biotherapies in systemic lupus erythematosus: New targets.

Joint Bone Spine 2017 May 21;84(3):267-274. Epub 2016 Sep 21.

Université de Bordeaux, 146, rue Léo-Saignat, 33076 Bordeaux, France; FHU ACRONIM, centre hospitalier universitaire de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux, France; CNRS-UMR 5164 Immuno Concept, 146, rue Léo-Saignat, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.jbspin.2016.07.004DOI Listing
May 2017

Activation, senescence and inflammation markers in HIV patients: association with renal function.

AIDS 2017 05;31(8):1119-1128

aUniversity Bordeaux, ISPED, Inserm, Bordeaux Population Health Research Center, Team MORPH3EUS, UMR 1219, CIC-EC 1401 bCNRS-UMR 5164 Immuno ConcEpT, Bordeaux University and Bordeaux Hospital cCHU de Bordeaux, Service de médecine interne et immunologie clinique dCHU de Bordeaux, Service de Maladies infectieuses et Tropicales eCHU de Bordeaux, Service de néphrologie, transplantation et dialyse fCHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, University Bordeaux, Bordeaux gCHU de Bordeaux, Service de Médecine Interne, Hôpital Haut-Lévêque, Pessac hCHU de Bordeaux, Pôle de santé publique iCHU de Bordeaux, service de Médecine Interne et Maladies Infectieuses, Bordeaux, France. *Alexandra Ozanne, Pierre Duffau, Linda Wittkop and Isabelle Pellegrin contributed equally to the article.

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http://dx.doi.org/10.1097/QAD.0000000000001461DOI Listing
May 2017

T follicular helper cells, interleukin-21 and systemic lupus erythematosus.

Rheumatology (Oxford) 2017 04;56(4):516-523

UMR-CNRS 5164 Université Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1093/rheumatology/kew297DOI Listing
April 2017

A unilateral erosive arthritis in a patient with systemic lupus erythematosus.

Joint Bone Spine 2017 03 3;84(2):245-246. Epub 2016 Jun 3.

Service de Rhumatologie, Hôpital Pellegrin, CHU de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux, France; Université de Bordeaux, 146, rue Léo-Saignat, 33076 Bordeaux, France; ALYSAI, CNRS-UMR 5164, 146, rue Léo-Saignat, 33076 Bordeaux, France.

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http://dx.doi.org/10.1016/j.jbspin.2016.03.009DOI Listing
March 2017

Mitochondria as Molecular Platforms Integrating Multiple Innate Immune Signalings.

J Mol Biol 2017 01 27;429(1):1-13. Epub 2016 Oct 27.

Bordeaux University, CIRID, 33000 Bordeaux, France; CNRS, UMR 5164, 146 rue Léo Saignat, 33076 Bordeaux, France. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2016.10.028DOI Listing
January 2017

CD95-Mediated Calcium Signaling Promotes T Helper 17 Trafficking to Inflamed Organs in Lupus-Prone Mice.

Immunity 2016 07;45(1):209-23

Centre Eugène Marquis, Rue Bataille Flandres Dunkerque, 35042 Rennes, France; INSERM ERL440-OSS, Equipe Labellisée, Ligue Contre Le Cancer, 35042 Rennes, France; Université de Rennes 1, 2 Ave. du Prof. Léon Bernard, 35043 Rennes, France; Biosit, Plateforme H2P2, Biogenouest, 2 Ave. du Prof. Léon Bernard, 35043 Rennes, France. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.06.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4961226PMC
July 2016

Understanding flow patterns and inflammatory status in intracranial aneurysms: Towards a personalized medicine.

J Neuroradiol 2016 Mar 14;43(2):141-7. Epub 2015 Nov 14.

Department of Neuroradiology, University Hospital of Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1016/j.neurad.2015.09.005DOI Listing
March 2016

Role of extracellular vesicles in autoimmune diseases.

Autoimmun Rev 2016 Feb 7;15(2):174-83. Epub 2015 Nov 7.

UMR-5164 CNRS, CIRID, University of Bordeaux, 146 rue Léo Saignat, 33076 Bordeaux Cedex, France; Internal Medicine and Clinical Immunology Department, Bordeaux Hospital, 1 rue Jean Burguet, 33075 Bordeaux Cedex, France. Electronic address:

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http://dx.doi.org/10.1016/j.autrev.2015.11.004DOI Listing
February 2016

T follicular helper (Tfh) cells in lupus: Activation and involvement in SLE pathogenesis.

Eur J Immunol 2016 Feb;46(2):281-90

Baylor Institute for Immunology Research, Dallas, USA.

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http://dx.doi.org/10.1002/eji.201545760DOI Listing
February 2016

Association of immune-activation and senescence markers with non-AIDS-defining comorbidities in HIV-suppressed patients.

AIDS 2015 Oct;29(16):2099-108

aCHU de Bordeaux, Service de médecine interne et immunologie clinique Bordeaux bUniversity Bordeaux, CIRID cCNRS, CIRID, UMR 5164 dUniversity Bordeaux, ISPED eINSERM, ISPED, Centre INSERM U897-Epidemiologie-Biostatistique fCHU de Bordeaux, Pôle de santé publique, Service d'information médicale gCHU de Bordeaux, Service de Médecine interne et maladies infectieuses hCHU de Bordeaux, Laboratoire d'Immunologie et Immunogénétique, University Bordeaux iCHU de Bordeaux, Service de Maladies Infectieuses et Tropicales jINRIA, Equipe SISTM, Bordeaux, France. †Pierre Duffau and Linda Wittkop contributed equally to the writing of this article.

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http://pdfs.journals.lww.com/aidsonline/2015/10230/Associati
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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/QAD.0000000000000807DOI Listing
October 2015

OX40/OX40L axis: not a friend in autoimmunity.

Oncotarget 2015 Sep;6(26):21779-80

UMR-CNRS 5164, CIRID, F-33000 Bordeaux Cedex, France; CNRS, CIRID, UMR 5164, F-33000 Bordeaux, France; CHU de Bordeaux, F-33076 Bordeaux, France.

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http://dx.doi.org/10.18632/oncotarget.4973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673116PMC
September 2015

Septic shock sera containing circulating histones induce dendritic cell-regulated necrosis in fatal septic shock patients.

Crit Care Med 2015 Apr;43(4):e107-16

1Medical Intensive Care Unit, Saint Andre Hospital, University Hospital of Bordeaux, Bordeaux, France. 2CNRS UMR 5164 CIRID, University of Bordeaux, Bordeaux, France. 3INSERM U892-CRCNA, University of Angers, Angers, France. 4Laboratory of Immunology and Immunogenetics, University Hospital of Bordeaux, Bordeaux, France. 5GECMIA (Groupe Epidemiologie Clinique des Maladies Inflammatoires d'Aquitaine) Study Group, University Hospital of Bordeaux, Bordeaux, France. 6Department of Rheumatology, University Hospital of Bordeaux, Bordeaux, France. 7Department of Internal Medicine, University Hospital of Bordeaux, Bordeaux, France. 8Department of Infectious and Tropical Diseases, University Hospital of Bordeaux, Bordeaux, France. 9Department of Interventional Cardiology, University Hospital of Bordeaux, Bordeaux, France. 10Medical Intensive Care Unit, Pellegrin Hospital, University Hospital of Bordeaux, Bordeaux, France.

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http://dx.doi.org/10.1097/CCM.0000000000000879DOI Listing
April 2015

Platelets: active players in the pathogenesis of arthritis and SLE.

Nat Rev Rheumatol 2012 Sep 7;8(9):534-42. Epub 2012 Aug 7.

Centre de Recherche en Rhumatologie et Immunologie, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Faculté de Médecine de l'Université Laval, Québec, Room T1-49, 2705 Laurier Boulevard, QC G1V 4G2, Canada. eric.boilard@ crchuq.ulaval.ca

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http://dx.doi.org/10.1038/nrrheum.2012.118DOI Listing
September 2012

Tocilizumab treatment decreases circulating myeloid dendritic cells and monocytes, 2 components of the myeloid lineage.

J Rheumatol 2012 Jun 1;39(6):1192-7. Epub 2012 Apr 1.

Département de Rhumatologie, CHU Bordeaux, Hôpital Pellegrin, Place Amélie Raba Léon, 33076 Bordeaux, France.

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http://www.jrheum.org/cgi/doi/10.3899/jrheum.111439
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http://dx.doi.org/10.3899/jrheum.111439DOI Listing
June 2012

Role for toll-like receptors in autoimmune disease: the example of systemic lupus erythematosus.

Joint Bone Spine 2011 Mar 18;78(2):124-30. Epub 2010 Oct 18.

CNRS UMR 5164, 146 rue Léo-Saignat, 33076 Bordeaux, France.

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http://dx.doi.org/10.1016/j.jbspin.2010.09.005DOI Listing
March 2011

Role for interferon regulatory factors in autoimmunity.

Joint Bone Spine 2010 Dec 21;77(6):525-31. Epub 2010 Sep 21.

CNRS UMR 5164, université Bordeaux 2, 146, rue Léo-Saignat, 33076 Bordeaux, France.

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http://dx.doi.org/10.1016/j.jbspin.2010.08.005DOI Listing
December 2010

[Pathophysiology of systemic lupus erythematosus].

Presse Med 2007 May 5;36(5 Pt 2):825-34. Epub 2007 Jan 5.

Clinique de médecine interne, Hôpital Haut-Lévêque, Pessac, France.

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http://dx.doi.org/10.1016/j.lpm.2006.11.017DOI Listing
May 2007

Decrease in circulating dendritic cells predicts fatal outcome in septic shock.

Intensive Care Med 2007 Jan 8;33(1):148-52. Epub 2006 Nov 8.

Département de Réanimation Médicale et Urgences, Hôpital St André, CHU de Bordeaux, Bordeaux, France.

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http://link.springer.com/content/pdf/10.1007/s00134-006-0436
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http://link.springer.com/10.1007/s00134-006-0436-7
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http://dx.doi.org/10.1007/s00134-006-0436-7DOI Listing
January 2007

Altered dendritic cell distribution in patients with common variable immunodeficiency.

Arthritis Res Ther 2005 1;7(5):R1052-5. Epub 2005 Jul 1.

Department of Internal Medicine and Infectious Diseases, Haut-Lévêque Hospital, Pessac, France.

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http://dx.doi.org/10.1186/ar1774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1257427PMC
April 2006

CD8+HLA-DR+ T lymphocytes are increased in common variable immunodeficiency patients with impaired memory B-cell differentiation.

Clin Immunol 2006 Apr 18;119(1):51-8. Epub 2006 Jan 18.

Department of Internal Medicine and Infectious Diseases, Haut-Lévêque Hospital, 5, avenue Magellan, 33604 Pessac, France.

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http://linkinghub.elsevier.com/retrieve/pii/S152166160500368
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http://dx.doi.org/10.1016/j.clim.2005.11.011DOI Listing
April 2006

Cytotoxic T lymphocytes and autoimmunity.

Curr Opin Rheumatol 2005 Nov;17(6):731-4

Clinique de Médecine Interne, Hôpital Haut-Lévêque, Pessac, France.

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http://dx.doi.org/10.1097/01.bor.0000179942.27777.f8DOI Listing
November 2005

Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus.

Arthritis Rheum 2005 Jan;52(1):201-11

CNRS-UMR5164 and IFR66, Université de Bordeaux 2, Place Amélie Raba Léon, 33076 Bordeaux, France.

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http://dx.doi.org/10.1002/art.20745DOI Listing
January 2005

Bone-marrow fibrin-ring granuloma.

Lancet 2003 Oct;362(9391):1224

Clinique de Médecine Interne et Maladies Infectieuses, Hôpital Haut-Lévêque, 33604 Cedex, Pessac, France.

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http://dx.doi.org/10.1016/S0140-6736(03)14545-XDOI Listing
October 2003

[Celiac disease and autoimmune diseases or systemic disease. Six cases and a review of the literature].

Ann Med Interne (Paris) 2003 Sep;154(4):197-204

Service des Maladies du Sang, Centre François-Magendie, CHU du Haut-Lévêque, 33604 Pessac.

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September 2003

Dendritic cells: controllers of the immune system and a new promise for immunotherapy.

Ann N Y Acad Sci 2003 Apr;987:180-7

Baylor Institute for Immunology Research, Dallas, Texas 75204, USA.

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http://dx.doi.org/10.1111/j.1749-6632.2003.tb06047.xDOI Listing
April 2003

Blood dendritic cells and DC-poietins in systemic lupus erythematosus.

Hum Immunol 2002 Dec;63(12):1172-80

Baylor Institute for Immunology Research, Dallas, Texas, USA.

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http://dx.doi.org/10.1016/s0198-8859(02)00756-5DOI Listing
December 2002

The interplay of dendritic cell subsets in systemic lupus erythematosus.

Immunol Cell Biol 2002 Oct;80(5):484-8

Baylor Institute for Immunology Research and University of Texas Southwestern Medical Center, Dallas 75204, USA.

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http://dx.doi.org/10.1046/j.1440-1711.2002.01112.xDOI Listing
October 2002