Patricia J Kiley

Patricia J Kiley

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Patricia J Kiley

Publications by authors named "Patricia J Kiley"

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Tailoring a Global Iron Regulon to a Uropathogen.

mBio 2020 Mar 24;11(2). Epub 2020 Mar 24.

Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA

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http://dx.doi.org/10.1128/mBio.00351-20DOI Listing
March 2020

Iron availability and oxygen tension regulate the Yersinia Ysc type III secretion system to enable disseminated infection.

PLoS Pathog 2019 12 23;15(12):e1008001. Epub 2019 Dec 23.

Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, CA United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1008001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946166PMC
December 2019

Phage integration alters the respiratory strategy of its host.

Elife 2019 10 25;8. Epub 2019 Oct 25.

Graduate Group in Biochemistry and Molecular Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, United States.

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http://dx.doi.org/10.7554/eLife.49081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814406PMC
October 2019

A Markerless Method for Genome Engineering in ZM4.

Front Microbiol 2019 11;10:2216. Epub 2019 Oct 11.

DOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, United States.

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http://dx.doi.org/10.3389/fmicb.2019.02216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6797605PMC
October 2019

Systems Metabolic Engineering of Escherichia coli Improves Coconversion of Lignocellulose-Derived Sugars.

Biotechnol J 2019 Sep 5;14(9):e1800441. Epub 2019 Aug 5.

US Department of Energy Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, 53711, USA.

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http://dx.doi.org/10.1002/biot.201800441DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718303PMC
September 2019

Control of Heme Uptake Genes in in Response to Iron Sources.

Front Cell Infect Microbiol 2018 22;8:47. Epub 2018 Feb 22.

Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, CA, United States.

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http://dx.doi.org/10.3389/fcimb.2018.00047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827684PMC
February 2019

Reassessing the Structure and Function Relationship of the O Sensing Transcription Factor FNR.

Antioxid Redox Signal 2018 12 14;29(18):1830-1840. Epub 2017 Nov 14.

Department of Biomolecular Chemistry, University of Wisconsin-Madison , Madison, Wisconsin.

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http://dx.doi.org/10.1089/ars.2017.7365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6217745PMC
December 2018

Regulated Stochasticity in a Bacterial Signaling Network Permits Tolerance to a Rapid Environmental Change.

Cell 2018 03 1;173(1):196-207.e14. Epub 2018 Mar 1.

Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Physics & Astronomy, University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5866230PMC
March 2018

O availability impacts iron homeostasis in .

Proc Natl Acad Sci U S A 2017 11 30;114(46):12261-12266. Epub 2017 Oct 30.

Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI 53706;

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http://www.pnas.org/lookup/doi/10.1073/pnas.1707189114
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http://dx.doi.org/10.1073/pnas.1707189114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699043PMC
November 2017

How Is Fe-S Cluster Formation Regulated?

Annu Rev Microbiol 2015 ;69:505-26

Department of Biomolecular Chemistry, School of Medicine and Public Health, University of Wisconsin-Madison, email: ,

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http://dx.doi.org/10.1146/annurev-micro-091014-104457DOI Listing
June 2016

Defining bacterial regulons using ChIP-seq.

Methods 2015 Sep 29;86:80-8. Epub 2015 May 29.

Department of Biomolecular Chemistry, University of Wisconsin - Madison, Madison, WI 53706, USA; Great Lakes Bioenergy Research Center, University of Wisconsin - Madison, Madison, WI 53706, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2015.05.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577457PMC
September 2015

Design principles of a conditional futile cycle exploited for regulation.

Mol Biosyst 2015 Jul;11(7):1841-9

Biomedical Engineering Department, University of California, One Shields Ave, Davis, CA 95616, USA.

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http://dx.doi.org/10.1039/c5mb00055fDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470783PMC
July 2015

Fe-S proteins that regulate gene expression.

Biochim Biophys Acta 2015 Jun 20;1853(6):1284-93. Epub 2014 Nov 20.

University of Wisconsin-Madison, Department of Biomolecular Chemistry, 440 Henry Mall, Biochemical Sciences Building, Room 4204C, Madison, WI 53706, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2014.11.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4390428PMC
June 2015

Coordinate regulation of the Suf and Isc Fe-S cluster biogenesis pathways by IscR is essential for viability of Escherichia coli.

J Bacteriol 2014 Dec 29;196(24):4315-23. Epub 2014 Sep 29.

Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA

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http://dx.doi.org/10.1128/JB.01975-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4248859PMC
December 2014

Aromatic inhibitors derived from ammonia-pretreated lignocellulose hinder bacterial ethanologenesis by activating regulatory circuits controlling inhibitor efflux and detoxification.

Front Microbiol 2014 13;5:402. Epub 2014 Aug 13.

Great Lakes Bioenergy Research Center, University of Wisconsin-Madison Madison, WI, USA ; Department of Biochemistry, University of Wisconsin-Madison Madison, WI, USA ; Department of Bacteriology, University of Wisconsin-Madison Madison, WI, USA.

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http://dx.doi.org/10.3389/fmicb.2014.00402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4132294PMC
September 2014

Transcriptome changes associated with anaerobic growth in Yersinia intermedia (ATCC29909).

PLoS One 2013 7;8(10):e76567. Epub 2013 Oct 7.

Biotechnology Center, University of Wisconsin - Madison, Madison, Wisconsin, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0076567PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792023PMC
August 2014

The influence of repressor DNA binding site architecture on transcriptional control.

mBio 2014 Aug 26;5(5):e01684-14. Epub 2014 Aug 26.

Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA

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http://dx.doi.org/10.1128/mBio.01684-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173790PMC
August 2014

IscR is essential for yersinia pseudotuberculosis type III secretion and virulence.

PLoS Pathog 2014 Jun 12;10(6):e1004194. Epub 2014 Jun 12.

Department of Microbiology and Environmental Toxicology, University of California Santa Cruz, Santa Cruz, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1004194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055776PMC
June 2014

The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally.

PLoS Genet 2013 17;9(10):e1003839. Epub 2013 Oct 17.

Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

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http://dx.plos.org/10.1371/journal.pgen.1003839
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http://dx.doi.org/10.1371/journal.pgen.1003839DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3798270PMC
March 2014

Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity.

Nat Struct Mol Biol 2013 Jun 5;20(6):740-7. Epub 2013 May 5.

Genomic Medicine Program, The Methodist Hospital Research Institute, Houston, Texas, USA.

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http://dx.doi.org/10.1038/nsmb.2568DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3676455PMC
June 2013

Genome-scale analysis of escherichia coli FNR reveals complex features of transcription factor binding.

PLoS Genet 2013 Jun 20;9(6):e1003565. Epub 2013 Jun 20.

Microbiology Doctoral Training Program, University of Wisconsin-Madison, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1371/journal.pgen.1003565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3688515PMC
June 2013

Regulation of iron-sulphur cluster homeostasis through transcriptional control of the Isc pathway by [2Fe-2S]-IscR in Escherichia coli.

Mol Microbiol 2013 Feb 17;87(3):478-92. Epub 2012 Oct 17.

Microbiology Doctoral Training Program, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1111/mmi.12052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4108476PMC
February 2013

Characterization of the [2Fe-2S] cluster of Escherichia coli transcription factor IscR.

Biochemistry 2012 Jun 24;51(22):4453-62. Epub 2012 May 24.

Department of Biomolecular Chemistry, University of Wisconsin, Madison, Wisconsin 53706, United States.

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http://dx.doi.org/10.1021/bi3003204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447993PMC
June 2012

Iron-containing transcription factors and their roles as sensors.

Curr Opin Chem Biol 2011 Apr 1;15(2):335-41. Epub 2011 Feb 1.

Department of Biomolecular Chemistry, University of Wisconsin School of Medicine and Public Health, Madison, WI 53706, United States.

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http://dx.doi.org/10.1016/j.cbpa.2011.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3074041PMC
April 2011

A shared mechanism of SoxR activation by redox-cycling compounds.

Mol Microbiol 2011 Mar 31;79(5):1119-22. Epub 2011 Jan 31.

Department of Biological Sciences, 1212 Amsterdam Avenue, Columbia University, New York, NY 10027, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2011.07552.xDOI Listing
March 2011

Reconstruction of the core and extended regulons of global transcription factors.

PLoS Genet 2010 Jul 22;6(7):e1001027. Epub 2010 Jul 22.

Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1001027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2908626PMC
July 2010

Global approaches for finding small RNA and small open reading frame functions.

J Bacteriol 2010 Jan;192(1):26-8

Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/JB.01316-09DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2798257PMC
January 2010

Techniques to isolate O2-sensitive proteins: [4Fe-4S]-FNR as an example.

Methods Enzymol 2009 ;463:787-805

School of Biological Sciences, The University of Hong Kong, Hong Kong, SAR.

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http://dx.doi.org/10.1016/S0076-6879(09)63042-1DOI Listing
January 2010

Dissecting the role of the N-terminal region of the Escherichia coli global transcription factor FNR.

J Bacteriol 2008 Dec 17;190(24):8230-3. Epub 2008 Oct 17.

Department of Biomolecular Chemistry, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1128/JB.01242-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2593217PMC
December 2008

The impact of O(2) on the Fe-S cluster biogenesis requirements of Escherichia coli FNR.

J Mol Biol 2008 Dec 10;384(4):798-811. Epub 2008 Oct 10.

Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, USA.

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http://dx.doi.org/10.1016/j.jmb.2008.09.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2648814PMC
December 2008

Contributions of [4Fe-4S]-FNR and integration host factor to fnr transcriptional regulation.

J Bacteriol 2007 Apr 9;189(8):3036-43. Epub 2007 Feb 9.

Department of Biomolecular Chemistry, University of Wisconsin-Madison, 1300 University Avenue, 574 MSC, Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/JB.00052-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1855857PMC
April 2007

Regulation of FNR dimerization by subunit charge repulsion.

J Biol Chem 2006 Nov 7;281(44):33268-75. Epub 2006 Sep 7.

Department of Chemistry, Monmouth College, Monmouth, Illinois 61462, USA.

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http://dx.doi.org/10.1074/jbc.M608331200DOI Listing
November 2006

IscR-dependent gene expression links iron-sulphur cluster assembly to the control of O2-regulated genes in Escherichia coli.

Mol Microbiol 2006 May;60(4):1058-75

Microbiology Doctoral Training Program, Department of Biomolecular Chemistry, University of Winsconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1111/j.1365-2958.2006.05160.xDOI Listing
May 2006

ClpXP-dependent proteolysis of FNR upon loss of its O2-sensing [4Fe-4S] cluster.

J Mol Biol 2005 Nov 7;354(2):220-32. Epub 2005 Oct 7.

Department of Biomolecular Chemistry, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1016/j.jmb.2005.09.066DOI Listing
November 2005

Kinetic analysis of the oxidative conversion of the [4Fe-4S]2+ cluster of FNR to a [2Fe-2S]2+ Cluster.

J Bacteriol 2004 Dec;186(23):8018-25

Program in Cellular & Molecular Biology, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/JB.186.23.8018-8025.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC529072PMC
December 2004

Exploiting thiol modifications.

PLoS Biol 2004 Nov 16;2(11):e400. Epub 2004 Nov 16.

Department of Biomolecular Chemistry, University of Wisconsin Medical School in Madison, Wisconsin, USA.

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http://dx.doi.org/10.1371/journal.pbio.0020400DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC526781PMC
November 2004

Techniques for studying the oxygen-sensitive transcription factor FNR from Escherichia coli.

Methods Enzymol 2003 ;370:300-12

Department of Biomolecular Chemistry, University of Wisconsin, 574 Medical Science Center, 1300 University Avenue, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1016/S0076-6879(03)70027-5DOI Listing
February 2004

Superoxide destroys the [2Fe-2S]2+ cluster of FNR from Escherichia coli.

Biochemistry 2004 Jan;43(3):791-8

Program in Cellular & Molecular Biology, University of Wisconsin, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1021/bi0357053DOI Listing
January 2004

The role of Fe-S proteins in sensing and regulation in bacteria.

Curr Opin Microbiol 2003 Apr;6(2):181-5

Department of Biomolecular Chemistry, Medical School, University of Wisconsin, 1300 University Avenue, Madison, Wisconsin 53706, USA.

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http://dx.doi.org/10.1016/s1369-5274(03)00039-0DOI Listing
April 2003

Characterization of activating region 3 from Escherichia coli FNR.

J Mol Biol 2002 Jan;315(3):275-83

Department of Bacteriology, University of Wisconsin, Madison, WI 53706, USA.

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http://dx.doi.org/10.1006/jmbi.2001.5241DOI Listing
January 2002