Publications by authors named "Patricia A Hebda"

56Publications

The Contractile Phenotype of Dermal Fetal Fibroblasts in Scarless Wound Healing.

Curr Pathobiol Rep 2017 Sep 28;5(3):271-277. Epub 2017 Jul 28.

Department of Plastic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1007/s40139-017-0149-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5640269PMC
September 2017

The Wound Healing Society celebrates 25 years.

Authors:
Patricia A Hebda

Wound Repair Regen 2013 Nov-Dec;21(6):771

Editor-in-Chief, Wound Repair and Regeneration Past President of the Wound Healing Society.

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http://dx.doi.org/10.1111/wrr.12124DOI Listing
November 2014

Role of steroids in acute phonotrauma: A basic science investigation.

Laryngoscope 2014 Apr 28;124(4):921-7. Epub 2014 Jan 28.

University of Pittsburgh Voice Center, Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/lary.23691DOI Listing
April 2014

Vocal exercise may attenuate acute vocal fold inflammation.

J Voice 2012 Nov;26(6):814.e1-13

Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.jvoice.2012.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509805PMC
November 2012

Cyclooxygenase-2 inhibition for the prevention of subglottic stenosis.

Arch Otolaryngol Head Neck Surg 2012 Oct;138(10):962-8

Division of Pediatric Otolaryngology, Children’s Hospital of Pittsburgh of the University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1001/archotol.2013.184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4126655PMC
October 2012

Novel rat model of tympanostomy tube otorrhea.

Int J Pediatr Otorhinolaryngol 2012 Feb 22;76(2):179-82. Epub 2011 Dec 22.

Department of Otolaryngology, University of Florida, Gainesville, FL 32610, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S01655876110056
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http://dx.doi.org/10.1016/j.ijporl.2011.11.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3260415PMC
February 2012

Biosimulation of acute phonotrauma: an extended model.

Laryngoscope 2011 Nov;121(11):2418-28

Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin, USA.

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http://dx.doi.org/10.1002/lary.22226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3360963PMC
November 2011

Biosimulation of inflammation and healing in surgically injured vocal folds.

Ann Otol Rhinol Laryngol 2010 Jun;119(6):412-23

Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910548PMC
http://dx.doi.org/10.1177/000348941011900609DOI Listing
June 2010

Subglottic stenosis examined as a fibrotic response to airway injury characterized by altered mucosal fibroblast activity.

Arch Otolaryngol Head Neck Surg 2010 Feb;136(2):163-70

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, PA 15224, USA.

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http://dx.doi.org/10.1001/archoto.2009.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000122PMC
February 2010

Translational systems biology and voice pathophysiology.

Laryngoscope 2010 Mar;120(3):511-5

Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.

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http://dx.doi.org/10.1002/lary.20755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3032590PMC
March 2010

Regeneration of epidermal appendages.

Authors:
Patricia A Hebda

Wound Repair Regen 2009 May-Jun;17(3):293

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http://dx.doi.org/10.1111/j.1524-475X.2009.00495.xDOI Listing
November 2009

Prostaglandin E2 is activated by airway injury and regulates fibroblast cytoskeletal dynamics.

Laryngoscope 2009 Jul;119(7):1365-73

Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15201, USA.

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http://dx.doi.org/10.1002/lary.20173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000119PMC
July 2009

Repair of the tympanic membrane with urinary bladder matrix.

Laryngoscope 2009 Jun;119(6):1206-13

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://doi.wiley.com/10.1002/lary.20233
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http://dx.doi.org/10.1002/lary.20233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3003594PMC
June 2009

Delayed reepithelialization and basement membrane regeneration after wounding in mice lacking CXCR3.

Wound Repair Regen 2009 Jan-Feb;17(1):34-41

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1111/j.1524-475X.2008.00439.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928121PMC
May 2009

ELR-negative CXC chemokine CXCL11 (IP-9/I-TAC) facilitates dermal and epidermal maturation during wound repair.

Am J Pathol 2008 Sep 31;173(3):643-52. Epub 2008 Jul 31.

Department of Pathology, University of Pittsburgh and Pittsburgh Veteran's Administration Medical Center, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.2353/ajpath.2008.070990DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527079PMC
September 2008

A patient-specific in silico model of inflammation and healing tested in acute vocal fold injury.

PLoS One 2008 Jul 30;3(7):e2789. Epub 2008 Jul 30.

Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0002789PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2481293PMC
July 2008

Acute and chronic changes in the subglottis induced by graded carbon dioxide laser injury in the rabbit airway.

Arch Otolaryngol Head Neck Surg 2008 Jul;134(7):694-702

Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Rangos Research Center, 3460 Fifth Ave, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1001/archotol.134.7.694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3000118PMC
July 2008

Prevention vs. cure.

Authors:
Patricia A Hebda

Wound Repair Regen 2008 Mar-Apr;16(2):144

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http://dx.doi.org/10.1111/j.1524-475X.2008.00353.xDOI Listing
June 2008

Age-dependent differential expression of fibronectin variants in skin and airway mucosal wounds.

Arch Otolaryngol Head Neck Surg 2007 Sep;133(9):919-24

Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, 8100 Rangos Research Center, 3460 Fifth Avenue, Pittsburgh, PA 15213, USA.

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http://archotol.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archotol.133.9.919DOI Listing
September 2007

Fetal dermal fibroblasts retain a hyperactive migratory and contractile phenotype under 2-and 3-dimensional constraints compared to normal adult fibroblasts.

Tissue Eng 2007 Nov;13(11):2791-801

Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1089/ten.2006.0412DOI Listing
November 2007

Delayed and deficient dermal maturation in mice lacking the CXCR3 ELR-negative CXC chemokine receptor.

Am J Pathol 2007 Aug 28;171(2):484-95. Epub 2007 Jun 28.

Department of Pathology, University of Pittsburgh and Pittsburgh VAMC, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.2353/ajpath.2007.061092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1934531PMC
August 2007

Differential regulation of free-floating collagen gel contraction by human fetal and adult dermal fibroblasts in response to prostaglandin E2 mediated by an EP2/cAMP-dependent mechanism.

Wound Repair Regen 2007 May-Jun;15(3):390-8

Pittsburgh Tissue Engineering Initiative; Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1524-475X.2007.00241.xDOI Listing
August 2007

Elucidating the role of interleukin 1beta and prostaglandin E2 in upper airway mucosal wound healing.

Arch Otolaryngol Head Neck Surg 2007 Apr;133(4):365-74

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1001/archotol.133.4.365DOI Listing
April 2007

Graded carbon dioxide laser-induced subglottic injury in the rabbit model.

Arch Otolaryngol Head Neck Surg 2007 Apr;133(4):358-64

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, PA, USA.

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http://dx.doi.org/10.1001/archotol.133.4.358DOI Listing
April 2007

Effects of ciprofloxacin-dexamethasone on myringotomy wound healing.

Laryngoscope 2007 Mar;117(3):522-8

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://doi.wiley.com/10.1097/MLG.0b013e31802f3c86
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http://dx.doi.org/10.1097/MLG.0b013e31802f3c86DOI Listing
March 2007

Prostaglandin E2 inhibition of keloid fibroblast migration, contraction, and transforming growth factor (TGF)-beta1-induced collagen synthesis.

Wound Repair Regen 2007 Jan-Feb;15(1):122-33

Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1111/j.1524-475X.2006.00193.xDOI Listing
June 2007

Primed fibroblasts and exogenous decorin: potential treatments for subacute vocal fold scar.

Otolaryngol Head Neck Surg 2006 Dec;135(6):937-45

University of Pittsburgh Voice Center, Department of Otolaryngology, PA 15213, USA.

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http://dx.doi.org/10.1016/j.otohns.2006.07.011DOI Listing
December 2006

Evaluation of microbial RNA extractions from Streptococcus pneumoniae.

J Microbiol Methods 2007 Feb 13;68(2):342-8. Epub 2006 Nov 13.

Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, 15213, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S016770120600278
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http://dx.doi.org/10.1016/j.mimet.2006.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1803758PMC
February 2007

Prostaglandin E2 differentially modulates human fetal and adult dermal fibroblast migration and contraction: implication for wound healing.

Wound Repair Regen 2006 Sep-Oct;14(5):633-43

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1111/j.1743-6109.2006.00156.xDOI Listing
February 2007

Gene expression patterns in isolated keloid fibroblasts.

Wound Repair Regen 2006 Jul-Aug;14(4):463-70

Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1111/j.1743-6109.2006.00135.xDOI Listing
January 2007

Dynamic biomechanical strain inhibits IL-1beta-induced inflammation in vocal fold fibroblasts.

J Voice 2007 Nov 14;21(6):651-60. Epub 2006 Aug 14.

Head and Neck Surgery, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/j.jvoice.2006.06.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948979PMC
November 2007

Fibroblast transplantation in the airway: implications for subglottic stenosis.

Arch Otolaryngol Head Neck Surg 2005 Dec;131(12):1090-6

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1001/archotol.131.12.1090DOI Listing
December 2005

Vocal fold wound healing: a review for clinicians.

J Voice 2006 Sep 1;20(3):432-42. Epub 2005 Dec 1.

Department of Head and Neck Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA.

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http://dx.doi.org/10.1016/j.jvoice.2005.08.005DOI Listing
September 2006

Identification of a pre-mRNA splicing factor, arginine/serine-rich 3 (Sfrs3), and its co-expression with fibronectin in fetal and postnatal rabbit airway mucosal and skin wounds.

Biochim Biophys Acta 2006 Jan 26;1762(1):34-45. Epub 2005 Aug 26.

Division of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.bbadis.2005.08.006DOI Listing
January 2006

Mucosal biofilm formation on middle-ear mucosa in a nonhuman primate model of chronic suppurative otitis media.

Laryngoscope 2005 Aug;115(8):1469-72

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, 3705 5th Avenue, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1097/01.mlg.0000172036.82897.d4DOI Listing
August 2005

Adult-fetal fibroblast interactions: effects on cell migration and implications for cell transplantation.

Cell Transplant 2005 ;14(5):331-7

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.3727/000000005783983025DOI Listing
October 2005

Gene expression profiles of early pneumococcal otitis media in the rat.

Int J Pediatr Otorhinolaryngol 2005 Oct;69(10):1383-93

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, and Department of Otolaryngology, University of Pittsburgh Medical School, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1016/j.ijporl.2005.03.033DOI Listing
October 2005

Biochemical markers associated with acute vocal fold wound healing: a rabbit model.

J Voice 2005 Jun;19(2):283-9

Department of Communication Science and Disorders, University of Pittsburgh, Pittsburgh, PA, USA.

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http://dx.doi.org/10.1016/j.jvoice.2004.04.003DOI Listing
June 2005

Mucosal wound healing in a rabbit model of subglottic stenosis: biochemical analysis of secretions.

Arch Otolaryngol Head Neck Surg 2005 Feb;131(2):153-7

Otolaryngology Wound Healing Laboratory, Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1001/archotol.131.2.153DOI Listing
February 2005

Recent advances in otitis media. 2. Eustachian tube, middle ear, and mastoid anatomy; physiology, pathophysiology, and pathogenesis.

Ann Otol Rhinol Laryngol Suppl 2005 Jan;194:16-30

Department of Otolaryngology, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1177/00034894051140s105DOI Listing
January 2005

Acute vocal fold wound healing in a rabbit model.

Ann Otol Rhinol Laryngol 2005 Jan;114(1 Pt 1):19-24

Department of Communication Science and Disorders the University of Pittsburgh Voice Center, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1177/000348940511400105DOI Listing
January 2005

Cathepsin gene expression profile in rat acute pneumococcal otitis media.

Laryngoscope 2004 Jun;114(6):1032-6

Department of Otolaryngology, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/00005537-200406000-00014DOI Listing
June 2004

Keloid fibroblast responsiveness to epidermal growth factor and activation of downstream intracellular signaling pathways.

Wound Repair Regen 2004 Mar-Apr;12(2):183-92

Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1111/j.1067-1927.2004.012111.xDOI Listing
September 2004

Markers of wound healing in vocal fold secretions from patients with laryngeal pathology.

Ann Otol Rhinol Laryngol 2004 Jan;113(1):23-9

Department of Otolaryngology and University of Pittsburgh Voice Center, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://journals.sagepub.com/doi/10.1177/000348940411300105
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http://dx.doi.org/10.1177/000348940411300105DOI Listing
January 2004

Shifts in biochemical markers associated with wound healing in laryngeal secretions following phonotrauma: a preliminary study.

Ann Otol Rhinol Laryngol 2003 Dec;112(12):1021-5

Department of Otolaryngology, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1177/000348940311201205DOI Listing
December 2003

Absence of inhibition of cutaneous wound healing in mice by oral doxycycline.

Wound Repair Regen 2003 Sep-Oct;11(5):373-9

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Rangos Research Center, 3460 Fifth Avenue, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1046/j.1524-475x.2003.11510.xDOI Listing
March 2004

Mucosal expression of genes encoding possible upstream regulators of Na+ transport during pneumococcal otitis media.

Acta Otolaryngol 2003 Jun;123(5):575-82

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh Pennsylvania 15213, USA.

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http://dx.doi.org/10.1080/00016480310002465DOI Listing
June 2003

The effect of changes in ambient oxygen concentration on the bioelectric properties of middle ear mucosa.

Am J Physiol Cell Physiol 2003 Sep 21;285(3):C618-22. Epub 2003 May 21.

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1152/ajpcell.00553.2002DOI Listing
September 2003

Impact of transplanted fibroblasts on rabbit skin wounds.

Arch Otolaryngol Head Neck Surg 2003 Mar;129(3):345-50

University of Pittsburgh School of Medicine, Pa, USA.

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http://dx.doi.org/10.1001/archotol.129.3.345DOI Listing
March 2003

Cytokine profiles in a rat model of otitis media with effusion caused by eustachian tube obstruction with and without Streptococcus pneumoniae infection.

Laryngoscope 2002 Sep;112(9):1657-62

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pennsyvania 15213, USA.

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http://dx.doi.org/10.1097/00005537-200209000-00024DOI Listing
September 2002

Suppression of epithelial ion transport transcripts during pneumococcal acute otitis media in the rat.

Acta Otolaryngol 2002 Jul;122(5):488-94

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, Pennsylvania 15213, USA.

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http://dx.doi.org/10.1080/00016480260092273DOI Listing
July 2002

Effect of 10 pharmacologic probes on mRNA levels of inducible nitric oxide synthetase and selected inflammatory cytokines in a rat model of acute otitis media.

Acta Otolaryngol 2002 Apr;122(3):255-61

Department of Pediatric Otolaryngology, Children's Hospital of Pittsburgh, University of Pittsburgh, Pennsylvania 15213-2583, USA.

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http://dx.doi.org/10.1080/000164802753648123DOI Listing
April 2002