Publications by authors named "Pasqualino De Antonellis"

26Publications

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.

Cell 2020 Jun 22;181(6):1329-1345.e24. Epub 2020 May 22.

The Arthur and Sonia Labatt Brain Tumor Research Center, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Developmental & Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G 1L7, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON M5G 1L7, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.04.047DOI Listing
June 2020

Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.

Nature 2019 10 9;574(7780):707-711. Epub 2019 Oct 9.

The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-019-1650-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7141958PMC
October 2019

Hepatocellular carcinoma: H-Prune gene regulatory networks.

EBioMedicine 2019 Mar 13;41:21-22. Epub 2019 Feb 13.

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6441999PMC
March 2019

Gene methylation in liquid biopsy and risk of recurrence in lung cancer.

J Thorac Dis 2018 Mar;10(3):1286-1289

Cell Biology and Biotherapy Unit, Istituto Nazionale Tumori "Fondazione G. Pascale"-IRCCS, Naples, Italy.

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http://dx.doi.org/10.21037/jtd.2018.02.84DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5906327PMC
March 2018

A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.

Cell 2018 02;172(5):1050-1062.e14

Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada; The Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada; Division of Neurosurgery, The Hospital for Sick Children, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.01.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346737PMC
February 2018

In vivo bioluminescence imaging using orthotopic xenografts towards patient's derived-xenograft Medulloblastoma models.

Q J Nucl Med Mol Imaging 2017 Mar 16;61(1):95-101. Epub 2016 Dec 16.

Department of Molecular Medicine and Medical Biotechnology, Università degli Studi di Napoli Federico II, Naples, Italy - CEINGE Biotecnologie Avanzate, Naples, Italy; European School of Molecular Medicine (SEMM), Milan, Italy.

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http://dx.doi.org/10.23736/S1824-4785.16.02959-9DOI Listing
March 2017

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors.

Authors:
Jonathon Torchia Brian Golbourn Shengrui Feng King Ching Ho Patrick Sin-Chan Alexandre Vasiljevic Joseph D Norman Paul Guilhamon Livia Garzia Natalia R Agamez Mei Lu Tiffany S Chan Daniel Picard Pasqualino de Antonellis Dong-Anh Khuong-Quang Aline C Planello Constanze Zeller Dalia Barsyte-Lovejoy Lucie Lafay-Cousin Louis Letourneau Mathieu Bourgey Man Yu Deena M A Gendoo Misko Dzamba Mark Barszczyk Tiago Medina Alexandra N Riemenschneider A Sorana Morrissy Young-Shin Ra Vijay Ramaswamy Marc Remke Christopher P Dunham Stephen Yip Ho-Keung Ng Jian-Qiang Lu Vivek Mehta Steffen Albrecht Jose Pimentel Jennifer A Chan Gino R Somers Claudia C Faria Lucia Roque Maryam Fouladi Lindsey M Hoffman Andrew S Moore Yin Wang Seung Ah Choi Jordan R Hansford Daniel Catchpoole Diane K Birks Nicholas K Foreman Doug Strother Almos Klekner Laszló Bognár Miklós Garami Péter Hauser Tibor Hortobágyi Beverly Wilson Juliette Hukin Anne-Sophie Carret Timothy E Van Meter Eugene I Hwang Amar Gajjar Shih-Hwa Chiou Hideo Nakamura Helen Toledano Iris Fried Daniel Fults Takafumi Wataya Chris Fryer David D Eisenstat Katrin Scheinemann Adam J Fleming Donna L Johnston Jean Michaud Shayna Zelcer Robert Hammond Samina Afzal David A Ramsay Nongnuch Sirachainan Suradej Hongeng Noppadol Larbcharoensub Richard G Grundy Rishi R Lulla Jason R Fangusaro Harriet Druker Ute Bartels Ronald Grant David Malkin C Jane McGlade Theodore Nicolaides Tarik Tihan Joanna Phillips Jacek Majewski Alexandre Montpetit Guillaume Bourque Gary D Bader Alyssa T Reddy G Yancey Gillespie Monika Warmuth-Metz Stefan Rutkowski Uri Tabori Mathieu Lupien Michael Brudno Ulrich Schüller Torsten Pietsch Alexander R Judkins Cynthia E Hawkins Eric Bouffet Seung-Ki Kim Peter B Dirks Michael D Taylor Anat Erdreich-Epstein Cheryl H Arrowsmith Daniel D De Carvalho James T Rutka Nada Jabado Annie Huang

Cancer Cell 2016 Dec;30(6):891-908

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5G0A4, Canada; Department of Paediatrics, University of Toronto, Toronto, ON M5G0A4, Canada; Division of Hematology/Oncology, Hospital for Sick Children, Toronto, ON M5G1X8, Canada; Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, ON M5G1X8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2016.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500911PMC
December 2016

MiR-34a deficiency accelerates medulloblastoma formation in vivo.

Int J Cancer 2015 May 25;136(10):2293-303. Epub 2014 Nov 25.

Department of Pediatric Oncology and Hematology, University Children's Hospital Essen, Hufelandstr. 55 45147, Essen, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany; German Cancer Research Center (DKFZ), D-69120, Heidelberg, Germany.

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http://dx.doi.org/10.1002/ijc.29294DOI Listing
May 2015

A therapeutic approach to treat prostate cancer by targeting Nm23-H1/h-Prune interaction.

Naunyn Schmiedebergs Arch Pharmacol 2015 Feb 20;388(2):257-69. Epub 2014 Aug 20.

Centro di Ingegneria Genetica e Biotecnologia Avanzate (CEINGE), Naples, Italy.

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http://dx.doi.org/10.1007/s00210-014-1035-8DOI Listing
February 2015

H-Prune through GSK-3β interaction sustains canonical WNT/β-catenin signaling enhancing cancer progression in NSCLC.

Oncotarget 2014 Jul;5(14):5736-49

Centro di Ingegneria Genetica e Biotecnologie Avanzate (CEINGE), Naples, Italy; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università 'Federico II' di Naples, Italy; Azienda Ospedaliera Federico II, DAI Medicina Trasfusionale Virologia, Naples, Italy.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170634PMC
http://dx.doi.org/10.18632/oncotarget.2169DOI Listing
July 2014

Early targets of miR-34a in neuroblastoma.

Mol Cell Proteomics 2014 Aug 9;13(8):2114-31. Epub 2014 Jun 9.

From the ‡Centro di Ingegneria Genetica e Biotecnologie Avanzate (CEINGE), 80145 Naples, Italy; §Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università Federico II, 80131 Naples, Italy; ‖‖Centro di Medicina Trasfusionale, Azienda Ospedaliera Federico II, 80131 Naples, Italy

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http://dx.doi.org/10.1074/mcp.M113.035808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4125741PMC
August 2014

Afatinib, a lung cancer inhibitor of ErbB family.

Naunyn Schmiedebergs Arch Pharmacol 2014 Jun 13;387(6):503-4. Epub 2014 Apr 13.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Università 'Federico II' di Napoli, Naples, Italy,

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http://dx.doi.org/10.1007/s00210-014-0980-6DOI Listing
June 2014

Cytogenetic prognostication within medulloblastoma subgroups.

J Clin Oncol 2014 Mar 3;32(9):886-96. Epub 2014 Feb 3.

David J.H. Shih, Marc Remke, Vijay Ramaswamy, Betty Luu, Yuan Yao, Xin Wang, Adrian M. Dubuc, Livia Garzia, John Peacock, Stephen C. Mack, Xiaochong Wu, Adi Rolider, A. Sorana Morrissy, Florence M.G. Cavalli, Claudia C. Faria, Stephen W. Scherer, Uri Tabori, Cynthia E. Hawkins, David Malkin, Eric Bouffet, James T. Rutka, and Michael D. Taylor, Hospital for Sick Children; David J.H. Shih, Marc Remke, Vijay Ramaswamy, Yuan Yao, Xin Wang, Adrian M. Dubuc, John Peacock, Stephen C. Mack, and Michael D. Taylor, University of Toronto, Toronto; Boleslaw Lach, McMaster University, Hamilton, Ontario; Jennifer A. Chan, University of Calgary, Calgary, Alberta; Steffen Albrecht, Adam Fontebasso, and Nada Jabado, McGill University, Montreal, Quebec, Canada; Paul A. Northcott, Andrey Korshunov, Marcel Kool, David T.W. Jones, and Stefan M. Pfister, German Cancer Research Center; Stefan M. Pfister, University Hospital Heidelberg, Heidelberg; Ulrich Schüller, Ludwig-Maximilians-University, Munich; Stefan Rutkowski, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Karel Zitterbart, Masaryk University School of Medicine; Karel Zitterbart and Leos Kren, University Hospital Brno, Brno, Czech Republic; Toshihiro Kumabe and Teiji Tominaga, Tohoku University Graduate School of Medicine, Sendai, Japan; Young Shin Ra, University of Ulsan, Asan Medical Center; Ji-Yeoun Lee, Byung-Kyu Cho, Seung-Ki Kim, and Kyu-Chang Wang, Seoul National University Children's Hospital, Seoul; Shin Jung, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Chonnam, South Korea; Peter Hauser and Miklós Garami, Semmelweis University, Budapest; László Bognár and Almos Klekner, University of Debrecen, Medical and Health Science Centre, Debrecen, Hungary; Shenandoah Robinson, Boston Children's Hospital; Scott L. Pomeroy, Harvard Medical School, Boston, MA; Ali G. Saad, University of Arkansas for Medical Sciences, Little

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http://dx.doi.org/10.1200/JCO.2013.50.9539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948094PMC
March 2014

MicroRNA 199b-5p delivery through stable nucleic acid lipid particles (SNALPs) in tumorigenic cell lines.

Naunyn Schmiedebergs Arch Pharmacol 2013 Apr 26;386(4):287-302. Epub 2013 Jan 26.

Dipartimento di Medicina Molecolare e Biotecnologie Mediche, Federico II University of Naples, Naples, Italy.

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http://dx.doi.org/10.1007/s00210-013-0837-4DOI Listing
April 2013

Novel pyrimidopyrimidine derivatives for inhibition of cellular proliferation and motility induced by h-prune in breast cancer.

Eur J Med Chem 2012 Nov 23;57:41-50. Epub 2012 Aug 23.

Dipartimento di Chimica delle Sostanze Naturali, Università degli Studi di Napoli Federico II, Via Domenico Montesano 49, 80131 Naples, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S022352341200499
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http://dx.doi.org/10.1016/j.ejmech.2012.08.020DOI Listing
November 2012

Molecular networks that regulate cancer metastasis.

Semin Cancer Biol 2012 Jun 30;22(3):234-49. Epub 2012 Mar 30.

CEINGE, Biotecnologie Avanzate, Naples, Italy.

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http://dx.doi.org/10.1016/j.semcancer.2012.03.006DOI Listing
June 2012

Norcantharidin impairs medulloblastoma growth by inhibition of Wnt/β-catenin signaling.

J Neurooncol 2012 Jan 7;106(1):59-70. Epub 2011 Jul 7.

CEINGE, Centro di Ingegneria Genetica, Biotecnologie Avanzate, Via Gaetano Salvatore 486, 80145 Naples, Italy.

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http://dx.doi.org/10.1007/s11060-011-0645-yDOI Listing
January 2012