Publications by authors named "Pasquale Chitano"

23Publications

Mechanopharmacology of Rho-kinase antagonism in airway smooth muscle and potential new therapy for asthma.

Pharmacol Res 2020 09 10;159:104995. Epub 2020 Jun 10.

The Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Canada.

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http://dx.doi.org/10.1016/j.phrs.2020.104995DOI Listing
September 2020

Upregulation of smooth muscle Rho-kinase protein expression in human asthma.

Eur Respir J 2020 03 5;55(3). Epub 2020 Mar 5.

Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1183/13993003.01785-2019DOI Listing
March 2020

The Huxley crossbridge model as the basic mechanism for airway smooth muscle contraction.

Am J Physiol Lung Cell Mol Physiol 2019 08 22;317(2):L235-L246. Epub 2019 May 22.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1152/ajplung.00051.2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6734385PMC
August 2019

Mechanopharmacology and Synergistic Relaxation of Airway Smooth Muscle.

J Eng Sci Med Diagn Ther 2019 Feb 13;2(1):0110041-110047. Epub 2019 Feb 13.

Department of Pathology and Laboratory Medicine, Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Vancouver, BC V6Z 1Y6, Canada.

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http://dx.doi.org/10.1115/1.4042477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164492PMC
February 2019

Smooth muscle function and myosin polymerization.

J Cell Sci 2017 Aug 8;130(15):2468-2480. Epub 2017 Jun 8.

Centre for Heart Lung Innovation - St Paul's Hospital, University of British Columbia, Vancouver, BC, Canada, V6Z 1Y6

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http://dx.doi.org/10.1242/jcs.202812DOI Listing
August 2017

Models to understand contractile function in the airways.

Authors:
Pasquale Chitano

Pulm Pharmacol Ther 2011 Oct 14;24(5):444-51. Epub 2011 Apr 14.

Division of Pulmonary and Sleep Medicine, Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/j.pupt.2011.04.028DOI Listing
October 2011

Reduced spontaneous relaxation in immature guinea pig airway smooth muscle is associated with increased prostanoid release.

Am J Physiol Lung Cell Mol Physiol 2008 May 7;294(5):L964-73. Epub 2008 Mar 7.

Division of Pediatric Pulmonary Medicine, Department of Pediatrics, Duke University Medical Center, Durham, NC, USA.

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http://dx.doi.org/10.1152/ajplung.00401.2007DOI Listing
May 2008

Airway smooth muscle relaxation is impaired in mice lacking the p47phox subunit of NAD(P)H oxidase.

Am J Physiol Lung Cell Mol Physiol 2008 Jan 9;294(1):L139-48. Epub 2007 Nov 9.

Dept. of Pediatrics and Neonatal Perinatal Research Institute, Duke Univ. Medical Center, Rm. 302, Bell Bldg., Box 2994, Durham, NC 27710, USA.

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http://dx.doi.org/10.1152/ajplung.00384.2007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3391573PMC
January 2008

Three paradigms of airway smooth muscle hyperresponsiveness in young guinea pigs.

Can J Physiol Pharmacol 2007 Jul;85(7):715-26

Division of Pediatric Pulmonary and Sleep Medicine and the Neonatal Perinatal Research Institute, Room 302, Bell Building, Duke University, Durham, NC 27710, USA.

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http://dx.doi.org/10.1139/Y07-063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527444PMC
July 2007

Nox4 mediates TGF-beta1-induced retinoblastoma protein phosphorylation, proliferation, and hypertrophy in human airway smooth muscle cells.

Am J Physiol Lung Cell Mol Physiol 2007 Jun 16;292(6):L1543-55. Epub 2007 Mar 16.

Division of Respiratory, Critical Care and Occupational Pulmonary Medicine, University of Utah Health Sciences Center and Veterans Administration Medical Center, Salt Lake City, Utah 84132, USA.

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http://dx.doi.org/10.1152/ajplung.00430.2006DOI Listing
June 2007

Mechanisms of airway smooth muscle relaxation during maturation.

Can J Physiol Pharmacol 2005 Oct;83(10):833-40

Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1139/y05-056DOI Listing
October 2005

A maturational model for the study of airway smooth muscle adaptation to mechanical oscillation.

Can J Physiol Pharmacol 2005 Oct;83(10):817-24

Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1139/y05-057DOI Listing
October 2005

S-nitrosoglutathione inhibits alpha1-adrenergic receptor-mediated vasoconstriction and ligand binding in pulmonary artery.

Am J Physiol Lung Cell Mol Physiol 2006 Jan 26;290(1):L136-43. Epub 2005 Aug 26.

Department of Pediatrics, University of Colorado Health Science Center, Denver, CO 80262, USA.

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http://dx.doi.org/10.1152/ajplung.00230.2005DOI Listing
January 2006

Maturation of guinea pig tracheal strip stiffness.

Am J Physiol Lung Cell Mol Physiol 2005 Dec 10;289(6):L902-8. Epub 2005 Jun 10.

Dept. of Pediatrics, Duke University Medical Center, Rm. 302, Bell Bldg., Box 2994, Durham, NC 27710, USA.

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http://dx.doi.org/10.1152/ajplung.00005.2005DOI Listing
December 2005

Length oscillation induces force potentiation in infant guinea pig airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2005 Dec 3;289(6):L909-15. Epub 2005 Jun 3.

Dept. of Pediatrics, Duke University Medical Center, Rm. 302, Bell Bldg., Box 2994, Durham, NC 27710, USA.

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http://dx.doi.org/10.1152/ajplung.00128.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527452PMC
December 2005

Ontogenesis of myosin light chain phosphorylation in guinea pig tracheal smooth muscle.

Pediatr Pulmonol 2005 Feb;39(2):108-16

Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1002/ppul.20150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527443PMC
February 2005

Growing up and advancing in airway smooth muscle research.

Trends Pharmacol Sci 2002 Oct;23(10):450-1

Division of Pediatric Pulmonary Medicine, Room 302, Bell Building, Box 2994, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1016/s0165-6147(02)02101-6DOI Listing
October 2002

Relaxation of guinea pig trachealis during electrical field stimulation increases with age.

J Appl Physiol (1985) 2002 May;92(5):1835-42

Department of Pediatrics, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1152/japplphysiol.00688.2001DOI Listing
May 2002

NADPH oxidase promotes NF-kappaB activation and proliferation in human airway smooth muscle.

Am J Physiol Lung Cell Mol Physiol 2002 Apr;282(4):L782-95

Department of Internal Medicine, Cannon Research Center, Carolinas Medical Center, Charlotte, NC 28232, USA.

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http://www.physiology.org/doi/10.1152/ajplung.00206.2001
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http://dx.doi.org/10.1152/ajplung.00206.2001DOI Listing
April 2002