Publications by authors named "Pascale Varlet"

100Publications

[Low grade glioma with MYBL1 alteration: Case report of an uncommon pediatric neoplasm].

Ann Pathol 2020 Jul 27. Epub 2020 Jul 27.

Service d'anatomie pathologique et de neuropathologie, hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille, 264, rue Saint-Pierre, 13005 Marseille cedex 5, France.

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http://dx.doi.org/10.1016/j.annpat.2020.07.003DOI Listing
July 2020

In Reply: High Prevalence of Developmental Venous Anomaly in Diffuse Intrinsic Pontine Gliomas: A Pediatric Control Study.

Neurosurgery 2020 Sep;87(4):E527

Service de Neurochirurgie GHU Paris-Hôpital Sainte-Anne Paris, France.

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http://dx.doi.org/10.1093/neuros/nyaa292DOI Listing
September 2020

Data Resource Profile: The French Childhood Cancer Observation Platform (CCOP).

Int J Epidemiol 2020 Jul 9. Epub 2020 Jul 9.

Epidémiologie des Cancers des Enfants et des Adolescents (EPICEA), Centre de Recherche en Epidémiologie et Statistiques (CRESS), INSERM, UMR 1153, Université de Paris, Paris, France.

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http://dx.doi.org/10.1093/ije/dyaa048DOI Listing
July 2020

Diffuse leptomeningeal glioneuronal tumor: a double misnomer? A report of two cases.

Acta Neuropathol Commun 2020 06 30;8(1):95. Epub 2020 Jun 30.

APHM, CHU Timone, Service d'Anatomie Pathologique et de Neuropathologie, Marseille, France.

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http://dx.doi.org/10.1186/s40478-020-00978-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325675PMC
June 2020

In Reply: High Prevalence of Developmental Venous Anomaly in Diffuse Intrinsic Pontine Gliomas: A Pediatric Control Study.

Neurosurgery 2020 02;86(2):E255

Department of Neurosurgery GHU Paris - Sainte-Anne Hospital Paris, France.

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http://dx.doi.org/10.1093/neuros/nyz448DOI Listing
February 2020

Rapid fully-automated assay for routine molecular diagnosis of mutations for personalized therapy of low grade gliomas.

Pediatr Hematol Oncol 2020 Feb 23;37(1):29-40. Epub 2019 Oct 23.

Université de Lorraine, CNRS UMR7039 CRAN, Institut de Cancérologie de Lorraine, Service de Biopathologie, Vandoeuvre-lès- Nancy, France.

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http://dx.doi.org/10.1080/08880018.2019.1679304DOI Listing
February 2020

MRI Atlas of IDH Wild-Type Supratentorial Glioblastoma: Probabilistic Maps of Phenotype, Management, and Outcomes.

Radiology 2019 12 8;293(3):633-643. Epub 2019 Oct 8.

From the Department of Neurosurgery, Sainte-Anne Hospital, Paris, France (A.R., M.Z., E.D., J.P.); Paris Descartes University, Sorbonne Paris Cité, Paris, France (A.R., P.R., M.E., M.Z., J.F.M., F.C., E.L., P.V., C.O., J.P.); UMR 1266 INSERM, IMA-BRAIN, Institute of Psychiatry and Neurosciences of Paris, Paris, France (A.R., P.R., M.E., K.S., M.Z., P.G., S.L., A.F., J.F.M., P.V., C.O., J.P.); Department of Neuroradiology, Sainte-Anne Hospital, Paris, France (M.E., J.F.M., C.O.); Department of Radiology, Juntendo University School of Medicine, Tokyo, Japan (K.S.); LTCI, Telecom ParisTech, Paris, France (P.G.); Department of Radiotherapy, Gustave Roussy University Hospital, Villejuif, France (F.D.); and Department of Neuropathology, Sainte-Anne Hospital, Paris, France (F.C., E.L., P.V.).

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http://dx.doi.org/10.1148/radiol.2019190491DOI Listing
December 2019

TP53 Pathway Alterations Drive Radioresistance in Diffuse Intrinsic Pontine Gliomas (DIPG).

Clin Cancer Res 2019 11 3;25(22):6788-6800. Epub 2019 Sep 3.

UMR8203, "Vectorologie & Thérapeutiques Anticancéreuses," CNRS, Gustave Roussy, Université Paris-Sud, Université Paris-Saclay, Villejuif, France.

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http://dx.doi.org/10.1158/1078-0432.CCR-19-0126DOI Listing
November 2019

Comparison of optically-derived biomarkers in healthy and brain tumor tissue under one- and two-photon excitation.

J Biophotonics 2019 11 23;12(11):e201900111. Epub 2019 Jul 23.

Imagerie et Modélisation en Neurobiologie et Cancérologie (IMNC), CNRS, Univ Paris Sud, Université Paris-Saclay, Orsay, France.

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http://dx.doi.org/10.1002/jbio.201900111DOI Listing
November 2019

H3F3A-G34R mutant high grade neuroepithelial neoplasms with glial and dysplastic ganglion cell components.

Acta Neuropathol Commun 2019 05 20;7(1):78. Epub 2019 May 20.

Department of Neuropathology, DGNN Brain Tumor Reference Center, University of Bonn Medical Center, Bonn, Germany.

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http://dx.doi.org/10.1186/s40478-019-0731-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526605PMC
May 2019

Developmental venous anomaly in adult patients with diffuse glioma: A clinically relevant coexistence?

Neurology 2019 01 30;92(1):e55-e62. Epub 2018 Nov 30.

From the Departments of Neurosurgery (A.R., M.Z., E.D., G.Z.-B., J.P.), Neuroradiology (M.E., S. Porelli, C.O), and Neuropathology (A.T.-E., P.V.), Sainte-Anne Hospital; Paris Descartes University (A.R., M.E., S. Porelli, A.T.-E., M.Z., E.D., G.Z.-B., S. Puget, P.V., C.O., J.P.), Sorbonne Paris Cité; Inserm (A.R., M.E., M.Z., E.D., P.V., C.O., J.P.), U894, IMA-Brain, Centre Psychiatrie et Neurosciences; Departments of Neuro-oncology (M.S.) and Neurosurgery (L.C.), Pitié-Salpêtrière Hospital; and Department of Pediatric Neurosurgery (S. Puget), Necker Hospital, Paris, France.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000006690DOI Listing
January 2019

Multimodal imaging to explore endogenous fluorescence of fresh and fixed human healthy and tumor brain tissues.

J Biophotonics 2019 03 23;12(3):e201800178. Epub 2018 Oct 23.

IMNC Laboratory, UMR 8165-CNRS/ IN2P3, Paris-Saclay University, Orsay, France.

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http://dx.doi.org/10.1002/jbio.201800178DOI Listing
March 2019

Combined Diffuse Astrocytoma and Pleomorphic Xanthoastrocytoma Grade III Sharing IDH1 R132H Mutation.

World Neurosurg 2018 Aug 30;116:316-321. Epub 2018 May 30.

Department of Neuropathology, Sainte-Anne Hospital, Descartes University, Paris, France.

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http://dx.doi.org/10.1016/j.wneu.2018.05.156DOI Listing
August 2018

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

Clinical, Radiologic, Pathologic, and Molecular Characteristics of Long-Term Survivors of Diffuse Intrinsic Pontine Glioma (DIPG): A Collaborative Report From the International and European Society for Pediatric Oncology DIPG Registries.

J Clin Oncol 2018 07 10;36(19):1963-1972. Epub 2018 May 10.

Lindsey M. Hoffman and Nicholas K. Foreman, University of Colorado Denver; Lindsey M. Hoffman and Nicholas K. Foreman, Children's Hospital Colorado, Aurora, CO; Sophie E.M. Veldhuijzen van Zanten, Esther Hulleman, Gertjan J.L. Kaspers, Esther Sanchez, and Dannis G. van Vuurden, Vrije Universiteit University Medical Center, Amsterdam; William P. Vandertop, Academy of Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands; Niclas Colditz, Marion Hoffmann, Brigitte Bison, Monika Warmuth-Metz, and Christof M. Kramm, University Medical Center Goettingen, Goettingen; Torsten Pietsch and Gerrit H. Gielen, University of Bonn Medical Center, Bonn; David T.W. Jones, Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, German Cancer Research Center, Hopp-Children's Cancer Center at the Nationale Centrum für Tumorerkrankungen Heidelberg, and German Consortium for Translational Cancer Research; Dominik Sturm, Stefan M. Pfister, and Elke Pfaff, Heidelberg University Hospital, Heidelberg, Germany; Joshua Baugh, Brooklyn Chaney, Adam Lane, Christine Fuller, Nancy Yanez Escorza, Renee Doughman, Rachid Drissi, James Leach, Blaise Jones, and Maryam Fouladi, Cincinnati Children's Hospital Medical Center, Cincinnati; Emmett Broxson, Wright State University and The Children's Medical Center, Dayton, OH; Lili Miles, Nemours Children's Hospital, Orlando, FL; Cynthia Hawkins, Ute Bartels, and Eric Bouffet, The Hospital for Sick Children, Toronto, Ontario; Anne Sophie Carret, Centre Hospitalier Universitaire Sainte-Justine; Nada Jabado, McGill University, Montreal, Quebec, Canada; Stewart Goldman, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL; Sarah Leary, Seattle Children's Hospital, University of Washington and Fred Hutchinson Cancer Research Center, Seattle, WA; Roger Packer, Children's National Health System; Javad Nazarian, Children's National Medical Center, Washington, DC; Katherine E. Warren, National Cancer Institute, Bethesda, MD; Alberto Broniscer, St Jude Children's Research Hospital, Memphis, TN; Mark W. Kieran, Dana-Farber Boston Children's Cancer and Blood Disorders Center, Boston, MA; Jane Minturn, Children's Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia; Melanie Comito, The Pennsylvania State University, Hershey, PA; Chie-Schin Shih, Indiana University, Indianapolis, IN; Soumen Khatua, The University of Texas MD Anderson Cancer Center; Murali Chintagumpala, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX; Timothy Hassall, Lady Cilento Children's Hospital, Brisbane, Queensland; David S. Ziegler, Kids Cancer Centre, Sydney Children's Hospital, Randwick; David S. Ziegler, University of New South Wales, Sydney, New South Wales; Nicholas Gottardo and Hetal Dholaria, Princess Margaret Hospital for Children, Perth, Western Australia, Australia; Martin Benesch, Medical University of Graz, Graz, Austria; Nathalie Boddaert. Stephanie Puget, and Raphaël Calmon, Hôpital Necker Enfants Malades; Pascale Varlet, Hôpital Sainte-Anne, Université Paris V Descartes, Sorbonne Paris Cité, Paris; Géraldine Giraud, David Castel, and Jacques Grill, Gustave Roussy, Université Paris-Sud, Université Paris-Saclay, Villejuif, France; Géraldine Giraud, Uppsala University, Uppsala, Sweden; Chris Jones, The Institute of Cancer Research, Sutton; Darren Hargrave, Great Ormond Street Hospital, London; Guirish A. Solanki, Birmingham Women's and Children's Hospital, Birmingham; Simon Bailey, Great North Children's Hospital, Victoria Wing, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom; Piergiorgio Modena and Marzia Giagnacovo, Sant' Anna Como General Hospital, Como; Manila Antonelli, Sapienza University of Rome, Rome; Veronica Biassoni and Maura Massimino, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milan, Italy; Nicolas U. Gerber and Michael A. Grotzer, University Children's Hospital of Zurich, Zurich; André O. von Bueren, University Hospital of Geneva and University of Geneva, Geneva, Switzerland; and Filip Jadrijevic Cvrlje and Gertjan J.L. Kaspers, Children's Hospital Zagreb, Zagreb, Croatia.

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http://dx.doi.org/10.1200/JCO.2017.75.9308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075859PMC
July 2018

Modeling the dynamics of oligodendrocyte precursor cells and the genesis of gliomas.

PLoS Comput Biol 2018 03 28;14(3):e1005977. Epub 2018 Mar 28.

IMNC Laboratory, CNRS, Univ Paris Saclay, Univ Paris-Sud, Univ Paris Diderot, France.

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http://dx.doi.org/10.1371/journal.pcbi.1005977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903643PMC
March 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.

Cancer Cell 2018 03;33(3):435-449.e6

Institut Curie - Recherche, Laboratoire 110, Centre Universitaire, Orsay Cedex 91405, France; INSERM U1021, Centre Universitaire, Orsay 91405, France; CNRS UMR 3347, Centre Universitaire, Orsay 91405, France; Université Paris Sud-11, 91405 Orsay, France; PSL Research University, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15356108183005
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http://dx.doi.org/10.1016/j.ccell.2018.02.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368680PMC
March 2018

Historadiological correlations in high-grade glioma with the histone 3.3 G34R mutation.

J Neuroradiol 2018 Sep 2;45(5):316-322. Epub 2018 Mar 2.

Department of Pathology, Sainte-Anne Hospital, université Paris-Descartes, U1000, France.

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http://dx.doi.org/10.1016/j.neurad.2018.02.006DOI Listing
September 2018

Functional-Based Resection Does Not Worsen Quality of Life in Patients with a Diffuse Low-Grade Glioma Involving Eloquent Brain Regions: A Prospective Cohort Study.

World Neurosurg 2018 May 9;113:e200-e212. Epub 2018 Feb 9.

Department of Neurosurgery, Sainte-Anne Hospital, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Paris, France; IMA-BRAIN, Inserm, U894, Centre de Psychiatrie et Neurosciences, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.wneu.2018.01.213DOI Listing
May 2018

Phase II, Open-Label, Randomized, Multicenter Trial (HERBY) of Bevacizumab in Pediatric Patients With Newly Diagnosed High-Grade Glioma.

J Clin Oncol 2018 04 7;36(10):951-958. Epub 2018 Feb 7.

Jacques Grill, Marie-Cécile Le Deley, and Gilles Vassal, Institut Gustave-Roussy, Villejuif; Marie-Cécile Le Deley, Paris-Saclay and Paris-Sud Universities, CESP, Institut National de la Santé et de la Recherche Médicale, Orsay; Pascale Varlet, Sainte-Anne Hospital, Paris, France; Maura Massimino, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milan; Felice Giangaspero, Sapienza University, Rome; Felice Giangaspero, IRCCS Neuromed, Pozzilli, Italy; Eric Bouffet, Hospital for Sick Children, Toronto, Ontario, Canada; Amedeo A. Azizi, Medical University of Vienna, Vienna, Austria; Geoffrey McCowage, Australasian Children's Cancer Trials, Clayton, Victoria, Australia; Adela Cañete, Hospital La Fe, Valencia, Spain; Frank Saran, The Royal Marsden Hospital; Chris Jones, The Institute of Cancer Research; Darren Hargrave, Great Ormond Street Hospital, London; Paul S. Morgan and Tim Jaspan, Nottingham University Hospitals, Queen's Medical Centre, Nottingham, United Kingdom; Helen Smith, Josep Garcia, Markus C. Elze, and Lauren Abrey, F. Hoffmann-La Roche Ltd, Basel, Switzerland; and Raphaël F. Rousseau, Gritstone Oncology, Emeryville, CA.

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http://dx.doi.org/10.1200/JCO.2017.76.0611DOI Listing
April 2018

Multimodal Magnetic Resonance Imaging of Treatment-Induced Changes to Diffuse Infiltrating Pontine Gliomas in Children and Correlation to Patient Progression-Free Survival.

Int J Radiat Oncol Biol Phys 2017 10 11;99(2):476-485. Epub 2017 Apr 11.

Pediatric Radiology Department, Hôpital Necker Enfants Malades, Paris, France; Institut National de la Santé et de la Recherche Médicale, Unité 1000, Paris, France; Imagine-Institut des Maladies Génétiques, UMR 1163, Paris, France; Université Paris Descartes, ComUE Sorbonne Paris Cité, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S03603016173080
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http://dx.doi.org/10.1016/j.ijrobp.2017.04.007DOI Listing
October 2017

Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours.

Acta Neuropathol Commun 2017 06 6;5(1):45. Epub 2017 Jun 6.

Children's Brain Tumour Research Centre (CBTRC), School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, NG7 2UH, UK.

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http://dx.doi.org/10.1186/s40478-017-0449-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5461722PMC
June 2017

Development of the SIOPE DIPG network, registry and imaging repository: a collaborative effort to optimize research into a rare and lethal disease.

J Neurooncol 2017 04 21;132(2):255-266. Epub 2017 Jan 21.

Department of Paediatrics, Division of Oncology/Haematology, VU University Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s11060-016-2363-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378734PMC
April 2017

Arterial Spin Labeling to Predict Brain Tumor Grading in Children: Correlations between Histopathologic Vascular Density and Perfusion MR Imaging.

Radiology 2016 Nov 3;281(2):553-566. Epub 2016 Jun 3.

From the Department of Pediatric Radiology, Hôpital Necker Enfants Malades, AP-HP, 149 rue de Sèvres, 75105 Paris, France (V.D., E.S., D.G., R.C., F.B., N.B.); INSERM U1000, Paris, France (V.D., D.G., R.C., F.B., P.V., N.B.); IMNC, UMR 8165 CNRS, University Paris Diderot and University Paris Sud, Campus d'Orsay, Orsay, France (C. Deroulers, M.B.); Clinical Research Unit, Hôpital Tarnier, AP-HP, Paris, France (F.F.); UMR 1163, Institut Imagine, Paris, France (D.G., R.C., F.B., N.B.); University René Descartes, PRES Sorbonne Paris Cité, Paris, France (R.C., M.P., T.B., S.P., M.Z., C.S., F.B., P.V., N.B.); Department of Neuropathology, Centre Hospitalier Sainte Anne, Paris, France (M.P., P.V.); Department of Pediatric and Adolescent Oncology, Gustave Roussy Institute, Villejuif, France (J.G., C. Dufour); CNRS, UMR 8203, Gustave Roussy Institute, University Paris-Sud, Villejuif, France (J.G., C. Dufour); and Department of Pediatric Neurosurgery, Hôpital Necker Enfants Malades, Paris, France (T.B., S.P., M.Z., C.S.).

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http://dx.doi.org/10.1148/radiol.2016152228DOI Listing
November 2016

Clinical, Imaging, Histopathological and Molecular Characterization of Anaplastic Ganglioglioma.

J Neuropathol Exp Neurol 2016 Oct 18;75(10):971-980. Epub 2016 Aug 18.

From the Department of Neurosurgery(MZ, ED, BD, JP), Department of Neuropathology, Sainte-Anne Hospital, Paris, France(MP, AT-E, FC, FA, PV), Department of Biochemistry, Paul Brousse Hospital, Paris, France(RS) Department of Pediatric Neurosurgery, Necker Enfants Malades Hospital, Paris, France(SP, CS-R, MZ), Paris Descartes University, Paris, France(MZ, MP, AT-E, SP, ED, BD, FC, FA, CS-R, MZ, J-FM, JP, PV), Department of Medical Biology and Pathology(LL), Department of Neurooncology, Gustave Roussy Institute, Villejuif, France(FD, SD, GL), Department of Neuroradiology, Sainte-Anne Hospital, Paris, France(J-FM) and Department of Pediatric Oncology, Gustave Roussy Institute, Villejuif, France(JG, CD).

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http://dx.doi.org/10.1093/jnen/nlw074DOI Listing
October 2016

The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.

EMBO Mol Med 2016 05 2;8(5):511-26. Epub 2016 May 2.

INSERM, UMR-S 1130, Neuroscience Paris Seine-IBPS, Paris, France CNRS, UMR 8246, Neuroscience Paris Seine-IBPS, Paris, France Sorbonne Universités, UPMC Université Paris 06, UMR-S 8246, Neuroscience Paris Seine-IBPS, Paris, France

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http://dx.doi.org/10.15252/emmm.201505421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130115PMC
May 2016

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Authors:
Dominik Sturm Brent A Orr Umut H Toprak Volker Hovestadt David T W Jones David Capper Martin Sill Ivo Buchhalter Paul A Northcott Irina Leis Marina Ryzhova Christian Koelsche Elke Pfaff Sariah J Allen Gnanaprakash Balasubramanian Barbara C Worst Kristian W Pajtler Sebastian Brabetz Pascal D Johann Felix Sahm Jüri Reimand Alan Mackay Diana M Carvalho Marc Remke Joanna J Phillips Arie Perry Cynthia Cowdrey Rachid Drissi Maryam Fouladi Felice Giangaspero Maria Łastowska Wiesława Grajkowska Wolfram Scheurlen Torsten Pietsch Christian Hagel Johannes Gojo Daniela Lötsch Walter Berger Irene Slavc Christine Haberler Anne Jouvet Stefan Holm Silvia Hofer Marco Prinz Catherine Keohane Iris Fried Christian Mawrin David Scheie Bret C Mobley Matthew J Schniederjan Mariarita Santi Anna M Buccoliero Sonika Dahiya Christof M Kramm André O von Bueren Katja von Hoff Stefan Rutkowski Christel Herold-Mende Michael C Frühwald Till Milde Martin Hasselblatt Pieter Wesseling Jochen Rößler Ulrich Schüller Martin Ebinger Jens Schittenhelm Stephan Frank Rainer Grobholz Istvan Vajtai Volkmar Hans Reinhard Schneppenheim Karel Zitterbart V Peter Collins Eleonora Aronica Pascale Varlet Stephanie Puget Christelle Dufour Jacques Grill Dominique Figarella-Branger Marietta Wolter Martin U Schuhmann Tarek Shalaby Michael Grotzer Timothy van Meter Camelia-Maria Monoranu Jörg Felsberg Guido Reifenberger Matija Snuderl Lynn Ann Forrester Jan Koster Rogier Versteeg Richard Volckmann Peter van Sluis Stephan Wolf Tom Mikkelsen Amar Gajjar Kenneth Aldape Andrew S Moore Michael D Taylor Chris Jones Nada Jabado Matthias A Karajannis Roland Eils Matthias Schlesner Peter Lichter Andreas von Deimling Stefan M Pfister David W Ellison Andrey Korshunov Marcel Kool

Cell 2016 Feb;164(5):1060-1072

Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ) and German Cancer Consortium (DKTK), 69120 Heidelberg, Germany.

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http://www.cell.com/cell/pdf/S0092-8674(16)00055-6.pdf
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http://www.cell.com/cms/attachment/2048488015/2058390163/mmc
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http://linkinghub.elsevier.com/retrieve/pii/S009286741600055
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http://dx.doi.org/10.1016/j.cell.2016.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5139621PMC
February 2016

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups.

Neuro Oncol 2016 06 28;18(6):790-6. Epub 2016 Jan 28.

Institute of Neuropathology, University Hospital Münster, Münster, Germany (C.T., V.R., A.J., W.P., M.H.); Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany (M.S.); Core Facility Genomics of the Medical Faculty Münster, Münster, Germany (A.W.); Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany (S.H., U.K.); Department of Neuropathology, Institute for Pathology and Neuropathology, University of Tübingen, Tübingen, Germany (R.B.); Faculty of Medicine, Institute of Neuropathology, University of Duisburg-Essen, Essen, Germany (K.K.); Department of Neuropathology, Klinikum Bremen-Mitte, Bremen, Germany (M.B.); Institute of Neurology (Edinger Institute), Goethe University, Frankfurt, Germany (M.M.); Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany (T.P.); Department of Neuropathology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany (J.F.); Department of Neuropathology, Institute of Pathology, University of Würzburg, and Comprehensive Cancer Center Mainfranken (CCCM), Würzburg, Germany (C.M.M.); Department of Neuropathology, Sainte-Anne Hospital, Paris, France (P.V.); 2nd Department of Paediatrics, Semmelweis University, Budapest, Hungary (P.H.); Department of Hematopathology, Molecular Diagnostic Laboratory, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.O.); Children's Brain Tumour Research Centre, School of Medicine, Queen's Medical Centre, University of Nottingham, Nottingham, UK (R.G.G.); Department of Pediatric Hematology Oncology and Blood and Marrow Transplantation, Cleveland Clinic Children's Hospital, Cleveland, Ohio (J.E.W.); Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany (A.K., A.v.D., D.C.); Clinical Cooperation Unit Neuropathology, German Research Center (DKFZ), Heidelberg, Germany (A.K., A.v.D., D.C.); German Cancer Consortium (DKTK), German Cancer Research Ce

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4864264PMC
June 2016

Primary Leptomeningeal Gliomatosis in Children and Adults: A Morphological and Molecular Comparative Study With Literature Review.

Neurosurgery 2016 Mar;78(3):343-52

*Department of Pathology, Lariboisière Hospital, Paris, France; ‡Department of Pathology, La Timone, Marseille, France; §Department of Neuropathology, Sainte-Anne's Hospital, Paris, France; ¶Department of Pathology, Charles Nicolle Hospital, Rouen, France; ‖Department of Neuropediatry, La Timone, Marseille, France; #Department of Neurology, Jean Minjoz Hospital, Besançon, France; **Department of Pathology, Jean Minjoz Hospital, Besançon, France; ‡‡Department of Neuropediatry, Necker Hospital, Paris, France; §§Department of Oncology, Rennes Hospital, Rennes, France; ¶¶Department of Oncology, Gustave Roussy Institute, Paris, France; ‖‖Department of Pathology, Rennes Hospital, Rennes, France; ##Department of Pathology, CHU Est Lyon, Bron, France.

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March 2016

Biopsy in a series of 130 pediatric diffuse intrinsic Pontine gliomas.

Childs Nerv Syst 2015 Oct 9;31(10):1773-80. Epub 2015 Sep 9.

Department of Pediatric Neurosurgery, Necker Enfants Malades Hospital, 149 rue de Sèvres, 75015, Paris, France.

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October 2015

Pediatric infratentorial ganglioglioma.

Childs Nerv Syst 2015 Oct 9;31(10):1707-16. Epub 2015 Sep 9.

Department of Pediatric Neurosurgery, Necker Enfants Malades Hospital, 149 rue de Sèvres, 75015, Paris, France.

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October 2015

An Unusual Case of Constitutional Mismatch Repair Deficiency Syndrome With Anaplastic Ganglioglioma, Colonic Adenocarcinoma, Osteosarcoma, Acute Myeloid Leukemia, and Signs of Neurofibromatosis Type 1: Case Report.

Neurosurgery 2015 Jul;77(1):E145-52; discussion E152

*Department of Neurosurgery, Thomas Jefferson University and Jefferson Hospital for Neuroscience, Philadelphia, Pennsylvania; ‡Department of Neurosurgery, Sainte-Anne University Hospital, Paris, France; §Paris Descartes University, Paris, France; ¶Department of Neuropathology, Sainte-Anne Hospital, Paris, France; ‖Department of Pediatric Oncology, Gustave Roussy Institute, Villejuif, France; #Department of Medical Oncology, Gustave Roussy Institute, Villejuif, France; **Department of Radiotherapy, Gustave Roussy Institute, Villejuif, France; ‡‡Department of Hematology, Gustave Roussy Institute, Villejuif, France; §§Department of Pathology, Cochin Hospital, Paris, France; ¶¶Department of Gastroenterology, Gustave Roussy Institute, Villejuif, France; ‖‖Department of Pathology, Caen University Hospital, Caen, France.

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July 2015

Imaging of gliomas at 1.5 and 3 Tesla - A comparative study.

Neuro Oncol 2015 Jun 18;17(6):895-900. Epub 2014 Dec 18.

Neuroimaging Department, Centre Hospitalier Sainte-Anne, Paris, France (L.T., R.S.-S., O.N., C.M., J.-F.M., C.O.); Neurosurgery Department, Centre Hospitalier Sainte-Anne, Paris, France (E.D., B.D., J.P.); Neuropathology Department, Centre Hospitalier Sainte-Anne, Paris, France (P.V., F.C.); INSERM U 894 Centre Hospitalier Sainte-Anne, Paris, France (O.N., C.O.); Radiation Therapy and Physics Department, Gustave Roussy Institute, Villejuif, France (F.D.); Medical Oncology department, Gustave Roussy Institute, Villejuif, France (J.D.); Université Paris Descartes, Paris, France (O.N., P.V., F.C., J.-F.M., J.P., C.O.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483120PMC
June 2015

Arterial Spin Labeling MRI: a step forward in non-invasive delineation of focal cortical dysplasia in children.

Epilepsy Res 2014 Dec 13;108(10):1932-9. Epub 2014 Oct 13.

Université Paris Descartes, Sorbonne Paris Cité, Paris, France; INSERM U1129, Pediatric Epilepsies and Brain Plasticity, Paris, France; APHP, Department of Pediatric Neurology, Reference Centre for Rare Epilepsies, Hospital Necker, Paris, France.

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December 2014

Imaging growth and isocitrate dehydrogenase 1 mutation are independent predictors for diffuse low-grade gliomas.

Neuro Oncol 2014 Aug 20;16(8):1100-9. Epub 2014 May 20.

Cell Biology Laboratory, CHU Gui de Chauliac Hospital, Montpellier, France (C.G.); INSERM U1051 Institut des Neurosciences de Montpellier, Montpellier, France (C.G., H.D., L.B.); Centre des Collections Biologiques Hospitalières de Montpellier (CCBH-M), CHU Gui de Chauliac Hospital, Montpellier, France (C.G.); Réseau d'Etude des Gliomes, REG, Groland, France (C.G., M.B., L.B., L.C., L.T., J.P.); Department of Neuro-Oncology, Nancy Neurological Hospital, Nancy, France (M.B., H.D., J.D.); Department of Neurosurgery, Sainte-Anne Hospital, Paris, France (G.L.M., E.D., P.P., B.D., J.P.); University Paris Descartes, Paris, France (G.L.M., E.D., P.P., P.V., B.D., J.P.); Department of Neurosurgery, Gui de Chauliac Hospital, Montpellier, France (L.B., H.D.); Department of Neuropathology, Sainte-Anne Hospital, Paris, France (P.V.); Department of Neurosurgery, Pitié-Salpêtrière University Hospital, Paris, France (L.C.); Department of Neuro-Oncology, CHU de Poitiers, Université de Poitiers, Poitiers, France (L.T.).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4096178PMC
August 2014

[National network of paediatric central nervous system tumours reviewing by the Groupe d'Étude de Neuropathologie Oncologique Pediatrique (GENOP)].

Ann Pathol 2014 Feb 20;34(1):74-86. Epub 2014 Feb 20.

Neuro-oncology and neuro-inflammation team, Inserm U1028, CNRS UMR 5292, university Lyon-1, neuroscience center, 69000 Lyon, France; Centre de pathologie et de neuropathologie Est, hospices civils de Lyon, 69003 Lyon, France. Electronic address:

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February 2014