Pascal M Lavoie

Pascal M Lavoie

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Pascal M Lavoie

Pascal M Lavoie

Publications by authors named "Pascal M Lavoie"

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Rethinking management of neonates at risk of sepsis.

Lancet 2019 Jul;394(10195):279-281

Department of Pediatrics, University of British Columbia and Children's and Women's Health Centres, Vancouver, BC V6H3V4, Canada.

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http://dx.doi.org/10.1016/S0140-6736(19)31627-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675455PMC
July 2019

Evolution of Training Guidelines for Echocardiography Performed by the Neonatologist: Toward Hemodynamic Consultation.

J Am Soc Echocardiogr 2019 Jun 26;32(6):785-790. Epub 2019 Mar 26.

UI Stead Family Children's Hospital, University of Iowa, Iowa City, Iowa; Mount Sinai Hospital, and Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.echo.2019.02.002DOI Listing
June 2019

Congenital lactic acidosis, cerebral cysts and pulmonary hypertension in an infant with FOXRED1 related complex 1 deficiency.

Mol Genet Metab Rep 2019 Jun 30;19:100472. Epub 2019 Apr 30.

Head Division of Biochemical Genetics, BC Children's Hospital, University of British Columbia, Room K3-205, 4480 Oak Street, Vancouver, BC V6H 3V4, Canada.

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http://dx.doi.org/10.1016/j.ymgmr.2019.100472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495215PMC
June 2019

Genetics of bronchopulmonary dysplasia: When things do not match up, it is only the beginning.

J Pediatr 2019 May 6;208:298-299. Epub 2019 Feb 6.

Department of Pediatrics, Division of Neonatology, Children's and Women's Health Centre of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.jpeds.2019.01.014DOI Listing
May 2019

Congenital lactic acidosis, cerebral cysts and pulmonary hypertension in an infant with FOXRED1 related complex I deficiency.

Mol Genet Metab Rep 2019 Mar 18;18:32-38. Epub 2019 Jan 18.

University of British Columbia, Head Division of Biochemical Genetics, BC Children's Hospital, Room K3-205, 4480 Oak Street, Vancouver, BC V6H 3V4, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S22144269183009
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http://dx.doi.org/10.1016/j.ymgmr.2018.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6349952PMC
March 2019

Outcomes related to respiratory syncytial virus with an abbreviated palivizumab regimen in children with congenital heart disease: a descriptive analysis.

CMAJ Open 2019 Jan-Mar;7(1):E88-E93. Epub 2019 Feb 18.

Children's & Women's Health Centre of British Columbia (Claydon, Popescu, Christopherson, Human, Solimano, Lavoie); Divisions of Neonatology (Popescu, Shaiba, Solimano, Lavoie) and Cardiology (Human), Department of Pediatrics, University of British Columbia; British Columbia Children's Hospital Research Institute (Popescu, Human, Lavoie), Vancouver, BC; Victoria General Hospital (Taylor), Victoria, BC; University of Toronto (Shaiba), Toronto, Ont.

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http://cmajopen.ca/lookup/doi/10.9778/cmajo.20180167
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http://dx.doi.org/10.9778/cmajo.20180167DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6380901PMC
February 2019

Predictor variables for post-discharge mortality modelling in infants: a protocol development project.

Afr Health Sci 2018 Dec;18(4):1214-1225

Department of Anesthesiology, Pharmacology, and Therapeutics, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.4314/ahs.v18i4.43DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354852PMC
December 2018

Glucose control and autonomic response during acute stress in youth with type 1 diabetes: A pilot study.

Pediatr Diabetes 2018 08 7;19(5):1020-1024. Epub 2018 May 7.

Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/pedi.12680DOI Listing
August 2018

A Potential Role for the NOD1 Variant (rs6958571) in Gram-Positive Blood Stream Infection in ELBW Infants.

Neonatology 2017 3;112(4):354-358. Epub 2017 Aug 3.

Department of Pediatrics, Children's Mercy, Kansas City, MO, USA.

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http://dx.doi.org/10.1159/000477433DOI Listing
July 2018

A Time-Based Analysis of Inflammation in Infants at Risk of Bronchopulmonary Dysplasia.

J Pediatr 2018 01 31;192:60-65.e1. Epub 2017 Oct 31.

Neonatal Program, Children's and Women's Hospitals of British Columbia, Vancouver, British Columbia, Canada; BC Children's Hospital Research Institute, Vancouver, British Columbia, Canada; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jpeds.2017.09.011DOI Listing
January 2018

Cord blood hematopoietic cells from preterm infants display altered DNA methylation patterns.

Clin Epigenetics 2017 20;9:39. Epub 2017 Apr 20.

BC Children's Hospital Research Institute, Room 2082, 950W 28th Avenue, Vancouver, BC V5Z 4H4 Canada.

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http://dx.doi.org/10.1186/s13148-017-0339-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397745PMC
December 2017

Why haven't the documented benefits of probiotics on preterm babies led to their wider acceptance and use?

Acta Paediatr 2017 11 22;106(11):1720-1721. Epub 2017 Aug 22.

BC Children's Hospital Research Institute, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/apa.13893DOI Listing
November 2017

The phenotype and function of preterm infant monocytes: implications for susceptibility to infection.

J Leukoc Biol 2017 09 19;102(3):645-656. Epub 2017 Jun 19.

School of Paediatrics and Child Health, University of Western Australia, Crawley, Australia;

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http://dx.doi.org/10.1189/jlb.4RU0317-111RDOI Listing
September 2017

Cardiac Autonomic Function at Baseline and under Stress and Its Relationship to Circulatory Markers of Inflammation in Obese Compared to Nonobese Children: A Pilot Study.

Horm Res Paediatr 2016 23;85(5):339-46. Epub 2016 Apr 23.

Endocrinology and Diabetes Unit, BC Children's Hospital, The University of British Columbia, Vancouver, B.C., Canada.

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http://dx.doi.org/10.1159/000445685DOI Listing
April 2017

Antifungal Immunological Defenses in Newborns.

Front Immunol 2017 15;8:281. Epub 2017 Mar 15.

British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada; Department of Medicine, University of British Columbia, Vancouver, BC, Canada; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.3389/fimmu.2017.00281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350100PMC
March 2017

Characterizing the hypomethylated DNA methylation profile of nucleated red blood cells from cord blood.

Epigenomics 2016 11 30;8(11):1481-1494. Epub 2016 Sep 30.

Child & Family Research Institute, Vancouver, British Columbia, V5Z 4H4, Canada.

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http://dx.doi.org/10.2217/epi-2016-0069DOI Listing
November 2016

A Randomized Controlled Trial of the Use of Oral Glucose with or without Gentle Facilitated Tucking of Infants during Neonatal Echocardiography.

PLoS One 2015 23;10(10):e0141015. Epub 2015 Oct 23.

Child & Family Research Institute, Vancouver, Canada; Department of Occupational Science and Occupational Therapy, University of British Columbia, Vancouver, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0141015PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619855PMC
June 2016

Cerebral Palsy and Polymorphism of the Chemokine CCL18 in Very Preterm Children.

Neonatology 2015 20;108(2):124-9. Epub 2015 Jun 20.

PEDEGO Research Center, and Medical Research Center Oulu, University of Oulu, Oulu, Finland.

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https://www.karger.com/Article/FullText/430765
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http://dx.doi.org/10.1159/000430765DOI Listing
May 2016

An Immunological Perspective on Neonatal Sepsis.

Trends Mol Med 2016 Apr 15;22(4):290-302. Epub 2016 Mar 15.

Child and Family Research Institute, Vancouver, British Columbia, Canada; Experimental Medicine Program, Department of Medicine, University of British Columbia, Vancouver, Canada; Department of Pediatrics, University of British Columbia, Vancouver, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14714914160003
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http://dx.doi.org/10.1016/j.molmed.2016.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104533PMC
April 2016

Genes Encoding Vascular Endothelial Growth Factor A (VEGF-A) and VEGF Receptor 2 (VEGFR-2) and Risk for Bronchopulmonary Dysplasia.

Neonatology 2015 13;108(1):53-9. Epub 2015 May 13.

PEDEGO Research Center, and Medical Research Center Oulu, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1159/000381279DOI Listing
March 2016

Multiple Successful Angioembolizations for Refractory Cardiac Failure in a Preterm with Rapidly Involuting Congenital Hemangioma.

AJP Rep 2016 Mar 4;6(1):e99-e103. Epub 2016 Jan 4.

Children's and Women's Health Centre of British Columbia, Vancouver, Canada; Department of Pediatrics, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1055/s-0035-1570342DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4737636PMC
March 2016

Outcomes of Respiratory Syncytial Virus Immunoprophylaxis in Infants Using an Abbreviated Dosing Regimen of Palivizumab.

JAMA Pediatr 2016 Feb;170(2):174-6

Children's & Women's Health Centre of British Columbia, University of British Columbia, Vancouver7Canadian Center for Vaccinology, Halifax, Nova Scotia8Sidra Medical and Research Center, Doha, Qatar.

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http://archpedi.jamanetwork.com/article.aspx?doi=10.1001/jam
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http://dx.doi.org/10.1001/jamapediatrics.2015.3235DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647159PMC
February 2016

Attenuated innate immune defenses in very premature neonates during the neonatal period.

Pediatr Res 2015 Nov 17;78(5):492-7. Epub 2015 Jul 17.

Child & Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5059157PMC
http://dx.doi.org/10.1038/pr.2015.132DOI Listing
November 2015

Nucleated red blood cells impact DNA methylation and expression analyses of cord blood hematopoietic cells.

Clin Epigenetics 2015 11;7:95. Epub 2015 Sep 11.

Child & Family Research Institute, 950 W 28th Avenue, Vancouver, BC V5Z 4H4 Canada ; Department of Pediatrics, University of British Columbia, Vancouver, BC V6T 1Z3 Canada.

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http://dx.doi.org/10.1186/s13148-015-0129-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567832PMC
September 2015

Oral glucose during targeted neonatal echocardiography: is it useful?

Arch Dis Child Fetal Neonatal Ed 2015 Jul 8;100(4):F374-5. Epub 2015 Jun 8.

Children's & Women's Health Centre of British Columbia, Vancouver, British Columbia, Canada Department of Pediatrics/Division of Neonatology, University of British Columbia, Vancouver, British Columbia, Canada Occupational Science and Occupational Therapy, University of British Columbia, Vancouver, British Columbia, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5050030PMC
http://dx.doi.org/10.1136/archdischild-2015-308191DOI Listing
July 2015

Polymorphisms of the gene encoding Kit ligand are associated with bronchopulmonary dysplasia.

Pediatr Pulmonol 2015 Mar 9;50(3):260-270. Epub 2014 Mar 9.

Department of Pediatrics, Institute of Clinical Medicine, and Medical Research Center Oulu, University of Oulu, Oulu, Finland.

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http://dx.doi.org/10.1002/ppul.23018DOI Listing
March 2015

Impaired NLRP3 inflammasome activity during fetal development regulates IL-1β production in human monocytes.

Eur J Immunol 2015 Jan 17;45(1):238-49. Epub 2014 Nov 17.

Child & Family Research Institute, Vancouver, BC, Canada; Department of Experimental Medicine, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1002/eji.201444707DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619041PMC
January 2015

Neonatal pain-related stress and NFKBIA genotype are associated with altered cortisol levels in preterm boys at school age.

PLoS One 2013 16;8(9):e73926. Epub 2013 Sep 16.

Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada ; Developmental Neurosciences and Child Health, Child & Family Research Institute, Vancouver, BC, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073926PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774765PMC
May 2014

Surgical site infections in infants admitted to the neonatal intensive care unit.

J Pediatr Surg 2014 Mar;49(3):381-4

Children's & Women's Health Centre of British Columbia, Vancouver, BC, Canada V6H 3 N1; Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada V6T 1ZA; Child & Family Research Institute, Vancouver, BC, Canada V5Z4H4. Electronic address:

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http://dx.doi.org/10.1016/j.jpedsurg.2013.08.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756080PMC
March 2014

Attenuation of respiratory syncytial virus-induced and RIG-I-dependent type I IFN responses in human neonates and very young children.

J Immunol 2014 Feb 3;192(3):948-57. Epub 2014 Jan 3.

Department of Pediatrics, University of British Columbia and Children's and Women's Health Centre of British Columbia, Vancouver, British Columbia V6H 3V4, Canada.

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http://dx.doi.org/10.4049/jimmunol.1302007DOI Listing
February 2014

Neonatal sepsis due to coagulase-negative staphylococci.

Clin Dev Immunol 2013 22;2013:586076. Epub 2013 May 22.

Child and Family Research Institute, 4th Floor, Translational Research Building, 950 West 28th Avenue, Vancouver, BC, Canada V5Z 4H4.

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http://dx.doi.org/10.1155/2013/586076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674645PMC
December 2013

Inflammasome-mediated IL-1β production in humans with cystic fibrosis.

PLoS One 2012 23;7(5):e37689. Epub 2012 May 23.

Department of Microbiology & Immunology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037689PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359311PMC
October 2012

The developing human preterm neonatal immune system: a case for more research in this area.

Clin Immunol 2012 Oct 17;145(1):61-8. Epub 2012 Aug 17.

Child & Family Research Institute, 950 west 28th Avenue, Vancouver BC, Canada V5Z4H4.

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http://dx.doi.org/10.1016/j.clim.2012.08.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556448PMC
October 2012

Early inflammation in the absence of overt infection in preterm neonates exposed to intensive care.

Cytokine 2011 Dec 21;56(3):621-6. Epub 2011 Sep 21.

Child & Family Research Institute, Department of Pediatrics, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.cyto.2011.08.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4494824PMC
December 2011

Ex vivo purification and characterization of human invariant Natural Killer T cells.

J Immunol Methods 2011 Oct 11;373(1-2):1-7. Epub 2011 Aug 11.

Child & Family Research Institute, 950 West 28th Avenue, Vancouver BC, Canada.

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http://dx.doi.org/10.1016/j.jim.2011.08.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4619040PMC
October 2011

Do neonatologists limit parental decision-making authority? A Canadian perspective.

Early Hum Dev 2010 Dec 14;86(12):801-5. Epub 2010 Oct 14.

Division of Neonatology, Children's and Women's Hospitals of British Columbia, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1016/j.earlhumdev.2010.09.007DOI Listing
December 2010

Inflammatory response in preterm infants is induced early in life by oxygen and modulated by total parenteral nutrition.

Pediatr Res 2010 Sep;68(3):248-51

Division of Neonatology, Children's and Women's Health Centre of British Columbia, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1203/PDR.0b013e3181eb2f18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5647160PMC
September 2010

Genetics of bronchopulmonary dysplasia in the age of genomics.

Curr Opin Pediatr 2010 Apr;22(2):134-8

Child & Family Research Institute, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1097/MOP.0b013e328336eb85DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5104534PMC
April 2010

Incidence of septicemia immediately after elective gastrointestinal contrast procedures in infants: a cohort study.

J Pediatr Surg 2010 Mar;45(3):507-12

Children's and Women's Health Center of British Columbia, British Columbia, Canada.

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http://dx.doi.org/10.1016/j.jpedsurg.2009.07.023DOI Listing
March 2010

Neonatal innate TLR-mediated responses are distinct from those of adults.

J Immunol 2009 Dec 16;183(11):7150-60. Epub 2009 Nov 16.

Division of Infectious and Immunological Diseases, Department of Pediatrics, University of British Columbia, CFRI, 950 West 28th Avenue, Vancouver, BC, V5Z4H4, Canada.

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http://www.jimmunol.org/content/183/11/7150.full.pdf
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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.0901481
Publisher Site
http://dx.doi.org/10.4049/jimmunol.0901481DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556237PMC
December 2009

Heritability of bronchopulmonary dysplasia, defined according to the consensus statement of the national institutes of health.

Pediatrics 2008 Sep;122(3):479-85

FRCPC, Department of Pediatrics, Division of Neonatology, Children's and Women's Health Centre of British Columbia, Room 1R47, 4480 Oak St, Vancouver BC, Canada.

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http://dx.doi.org/10.1542/peds.2007-2313DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631604PMC
September 2008

Attitudes of Canadian neonatologists in delivery room resuscitation of newborns at threshold of viability.

J Obstet Gynaecol Can 2007 Sep;29(9):719-25

Division of Neonatology, Department of Pediatrics, Children's and Women's Health Centre of British Columbia, Vancouver, BC.

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September 2007

Gastrointestinal presentation of relative adrenal insufficiency in a sick preterm neonate.

Am J Perinatol 2007 Sep 12;24(8):493-5. Epub 2007 Sep 12.

Division of Neonatology, Department of Pediatrics, Children's & Women's Health Centre of British Columbia, Vancouver, BC, Canada.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-2007-986694
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http://dx.doi.org/10.1055/s-2007-986694DOI Listing
September 2007

Delayed expansion of a restricted T cell repertoire by low-density TCR ligands.

Int Immunol 2005 Jul 21;17(7):931-41. Epub 2005 Jun 21.

Laboratoire d'Immunologie, Centre de recherche du Centre Hospitalier de l'Université de Montréal, Hôpital Saint-Luc, Montréal, Québec H2X 1P1, Canada.

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http://dx.doi.org/10.1093/intimm/dxh273DOI Listing
July 2005

Lead poisoning from "lead-free" paint.

CMAJ 2004 Mar;170(6):956

Department of Pediatrics, Hôpital Sainte-Justine, Montréal, Que.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC359428PMC
March 2004