Publications by authors named "Pascal Finetti"

100Publications

Novel Therapeutic Insights in Dedifferentiated Liposarcoma: A Role for FGFR and MDM2 Dual Targeting.

Cancers (Basel) 2020 Oct 20;12(10). Epub 2020 Oct 20.

Institute for Research on Cancer and Aging, Nice (IRCAN), Institut National de la Santé et de la Recherche Médicale (INSERM) U1081, Centre National de la Recherche Scientifique (CNRS) UMR7284, Université Côte d'Azur, 06107 Nice, France.

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October 2020

Theranostic Targeting of CUB Domain Containing Protein 1 (CDCP1) in Pancreatic Cancer-Letter.

Clin Cancer Res 2020 Oct;26(20):5539

Laboratory of Predictive Oncology, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, Aix-Marseille Université, INSERM UMR1068, CNRS UMR725, Marseille, France.

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October 2020

Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?

Cancers (Basel) 2020 Sep 1;12(9). Epub 2020 Sep 1.

Predictive Oncology Laboratory, Cancer Research Center of Marseille (CRCM), Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix Marseille Université, 13009 Marseille, France.

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September 2020

Enhancement of Breast Cancer Cell Aggressiveness by lncRNA and its Mir-675 Derivative: Insight into Shared and Different Actions.

Cancers (Basel) 2020 Jun 29;12(7). Epub 2020 Jun 29.

University of Lille, CNRS, INSERM, CHU Lille, Centre Oscar Lambret, UMR 9020-UMR 1277-Canther-Cancer Heterogeneity, Plasticity and Resistance to Therapies, F-59000 Lille, France.

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June 2020

The therapeutic response of ER+/HER2- breast cancers differs according to the molecular Basal or Luminal subtype.

NPJ Breast Cancer 2020 6;6. Epub 2020 Mar 6.

Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille, Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix-Marseille Université, Marseille, France.

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March 2020

Inflammatory breast cancer cells are characterized by abrogated TGFβ1-dependent cell motility and SMAD3 activity.

Breast Cancer Res Treat 2020 Apr 10;180(2):385-395. Epub 2020 Feb 10.

Center for Oncological Research (CORE), Faculty of Medicine and Health Sciences - University of Antwerp, Campus Drie Eiken - Universiteitsplein 1, 2610, Wilrijk - Antwerp, Belgium.

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April 2020

expression is associated with longer postoperative, survival in adrenocortical carcinoma.

Oncoimmunology 2019;8(11):e1655362. Epub 2019 Aug 28.

Laboratoire Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille Université, Marseille, France.

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August 2019

Epigenetic down-regulation of the HIST1 locus predicts better prognosis in acute myeloid leukemia with NPM1 mutation.

Clin Epigenetics 2019 10 12;11(1):141. Epub 2019 Oct 12.

Epigenetic Factors in Normal and Malignant Hematopoiesis Team, Aix Marseille University, CNRS, Inserm, Institut Paoli-Calmettes, CRCM, 27 Boulevard Lei Roure, 13273, Marseille Cedex 09, France.

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October 2019

A Tyrosine Kinase Expression Signature Predicts the Post-Operative Clinical Outcome in Triple Negative Breast Cancers.

Cancers (Basel) 2019 Aug 13;11(8). Epub 2019 Aug 13.

Department of Medical Oncology, Institut Paoli-Calmettes, Aix-Marseille Univ, CRCM, CNRS, INSERM, 13000 Marseille, France.

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August 2019

Sensitive and easy screening for circulating tumor cells by flow cytometry.

JCI Insight 2019 06 13;5. Epub 2019 Jun 13.

Predictive Oncology Laboratory, Cancer Research Center of Marseille (CRCM), Inserm U1068, CNRS UMR7258, Institut Paoli-Calmettes, Aix Marseille Université, Marseille, France.

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June 2019

PARP1 expression in soft tissue sarcomas is a poor-prognosis factor and a new potential therapeutic target.

Mol Oncol 2019 07 7;13(7):1577-1588. Epub 2019 Jun 7.

Predictive Oncology Laboratory, Marseille Cancer Research Center (CRCM), Institut Paoli-Calmettes, U1068 INSERM, U7258 CNRS, Aix-Marseille University, Marseille, France.

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July 2019

A Comparison of DNA Mutation and Copy Number Profiles of Primary Breast Cancers and Paired Brain Metastases for Identifying Clinically Relevant Genetic Alterations in Brain Metastases.

Cancers (Basel) 2019 May 13;11(5). Epub 2019 May 13.

Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille (CRCM), Inserm, U1068, CNRS UMR7258, Aix-Marseille Université, Institut Paoli-Calmettes, F-13009 Marseille, France.

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May 2019

Expression Is a Poor-Prognosis Marker in Pancreatic Adenocarcinoma.

J Clin Med 2019 Apr 30;8(5). Epub 2019 Apr 30.

Laboratoire d'Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille, Aix-Marseille Université, INSERM UMR1068, CNRS UMR725, F-13273 Marseille, France.

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April 2019

ECT2 associated to PRICKLE1 are poor-prognosis markers in triple-negative breast cancer.

Br J Cancer 2019 04 11;120(9):931-940. Epub 2019 Apr 11.

Centre de Recherche en Cancérologie de Marseille, Equipe labellisée 'Predictive oncology' Ligue 2018, Aix Marseille Université, Inserm, CNRS, Institut Paoli Calmettes, 13009, Marseille, France.

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April 2019

Head and Body/Tail Pancreatic Carcinomas Are Not the Same Tumors.

Cancers (Basel) 2019 Apr 8;11(4). Epub 2019 Apr 8.

Laboratoire Oncologie Prédictive, Centre de Recherche en Cancérologie de Marseille, INSERM UMR1068, CNRS UMR725, Aix-Marseille Université, 13273 Marseille, France.

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April 2019

The SCRIB Paralog LANO/LRRC1 Regulates Breast Cancer Stem Cell Fate through WNT/β-Catenin Signaling.

Stem Cell Reports 2018 11 18;11(5):1040-1050. Epub 2018 Oct 18.

Centre de Recherche en Cancérologie de Marseille, CRCM, Aix Marseille University, Institut Paoli-Calmettes, CNRS, INSERM, 'Cell Polarity, Cell Signaling and Cancer'- Equipe Labellisée Ligue Contre le Cancer, Marseille, France. Electronic address:

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November 2018

CMTM6 stabilizes PD-L1 expression and refines its prognostic value in tumors.

Ann Transl Med 2018 Feb;6(3):54

Département d'Oncologie Moléculaire, ''Equipe labellisée Ligue Contre le Cancer,'' Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068, UMR7258 CNRS, Aix-Marseille Université, Marseille, France.

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February 2018

Molecular classification as prognostic factor and guide for treatment decision of pancreatic cancer.

Biochim Biophys Acta Rev Cancer 2018 Apr 28;1869(2):248-255. Epub 2018 Feb 28.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, Marseille, France; Faculté de Médecine, Aix-Marseille Université, Marseille, France.

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April 2018

"Wnt/β-Catenin in GIST"-Letter.

Mol Cancer Ther 2018 01;17(1):327-328

Department of Molecular Oncology, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Marseille, France.

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January 2018

Stromal Expression of MARCKS Protein in Ovarian Carcinomas Has Unfavorable Prognostic Value.

Int J Mol Sci 2017 Dec 23;19(1). Epub 2017 Dec 23.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Aix-Marseille Université, 13007 Marseille, France.

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December 2017

Validation and comparison of the molecular classifications of pancreatic carcinomas.

Mol Cancer 2017 11 6;16(1):168. Epub 2017 Nov 6.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Aix-Marseille Université, Marseille, France.

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November 2017

Wnt Signaling Inhibition Promotes Apoptosis in Sarcomas-Letter.

Mol Cancer Ther 2017 10;16(10):2324

Department of Molecular Oncology, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR7258, Marseille, France.

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October 2017

A 25-gene classifier predicts overall survival in resectable pancreatic cancer.

BMC Med 2017 09 20;15(1):170. Epub 2017 Sep 20.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Inserm UMR1068, CNRS UMR725, Aix-Marseille Université, Marseille, France.

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September 2017

Characterization and Targeting of Platelet-Derived Growth Factor Receptor alpha (PDGFRA) in Inflammatory Breast Cancer (IBC).

Neoplasia 2017 Jul 10;19(7):564-573. Epub 2017 Jun 10.

The Laboratory for Cytoskeletal Physiology, Department of Biological Sciences, The University of Delaware, Newark, DE; The Center for Translational Cancer Research, The University of Delaware, Newark, DE; The Helen F. Graham Cancer Center, Newark, DE. Electronic address:

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July 2017

PDL1 expression is a poor-prognosis factor in soft-tissue sarcomas.

Oncoimmunology 2017;6(3):e1278100. Epub 2017 Feb 8.

Department of Molecular Oncology, Institut Paoli-Calmettes, Centre de Recherche en Cancérologie de Marseille, UMR1068 Inserm , Marseille, France.

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February 2017

Prognostic Value of Molecular Subtypes in Pancreatic Cancer.

Pancreas 2017 04;46(4):e29-e31

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, INSERM UMR1068, CNRS UMR725, Aix-Marseille Université, Marseille, France, Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France, Faculté de Médecine, Aix-Marseille Université, Marseille, France, Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, INSERM UMR1068, CNRS UMR725, Aix-Marseille Université, Marseille, France, Faculté de Médecine, Aix-Marseille Université, Marseille, France, Département de Chirurgie Générale et Viscérale, AP-HM, Marseille, France Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, INSERM UMR1068, CNRS UMR725, Aix-Marseille Université, Marseille, France Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France Département d'Anatomopathologie, Institut Paoli-Calmettes, Marseille, France Département d'Oncologie Médicale, Institut Paoli-Calmettes, Marseille, France Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, INSERM UMR1068, CNRS UMR725, Aix-Marseille Université, Marseille, France.

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April 2017

Prognostic value of PDL1 expression in pancreatic cancer.

Oncotarget 2016 11;7(44):71198-71210

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, INSERM, CNRS, Université Aix-Marseille, Marseille, France.

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November 2016

XPO1, therapeutic … and prognostic target in sarcomas.

Oncoscience 2016 19;3(5-6):143-4. Epub 2016 May 19.

Department of Medical Oncology, Institut Paoli-Calmettes, Marseille, France.

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August 2016

Autocrine Secretion of Progastrin Promotes the Survival and Self-Renewal of Colon Cancer Stem-like Cells.

Cancer Res 2016 06 4;76(12):3618-28. Epub 2016 May 4.

CNRS, UMR-5203, Institut de Génomique Fonctionnelle, Montpellier, France. INSERM, U661, Montpellier, France. Universités de Montpellier 1 & 2, UMR-5203, Montpellier, France. Department of Pathology, The University of Melbourne, Parkville, Victoria, Australia.

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June 2016

PRICKLE1 Contributes to Cancer Cell Dissemination through Its Interaction with mTORC2.

Dev Cell 2016 May 12;37(4):311-325. Epub 2016 May 12.

Inserm, U1068, CRCM, Cell Polarity, Cell Signalling and Cancer "Equipe labellisée Ligue Contre le Cancer", Marseille 13009, France; Institut Paoli-Calmettes, Marseille 13009, France; Aix-Marseille Université, UM 105, Marseille 13284, France; CNRS, UMR7258, CRCM, Marseille 13009, France. Electronic address:

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May 2016

The PD1/PDL1 axis, a promising therapeutic target in aggressive breast cancers.

Oncoimmunology 2016 Mar 31;5(3):e1085148. Epub 2015 Aug 31.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725 , Marseille, France.

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March 2016

Expression of Genes with Copy Number Alterations and Survival of Patients with Pancreatic Adenocarcinoma.

Cancer Genomics Proteomics 2016 May-Jun;13(3):191-200

Department of Molecular Oncology UMR1068, Paoli-Calmettes Instituet, Marseille, France Aix-Marseille University, Marseille, France.

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January 2017

Comparative genomic analysis of primary tumors and metastases in breast cancer.

Oncotarget 2016 May;7(19):27208-19

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.

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May 2016

PLZF mutation alters mouse hematopoietic stem cell function and cell cycle progression.

Blood 2016 Apr 3;127(15):1881-5. Epub 2016 Mar 3.

INSERM U1068, Centre de Recherche en Cancérologie de Marseille, Marseille, France; Institut Paoli-Calmettes, Marseille, France; Aix-Marseille University, Unité Mixte 105, Marseille, France; Centre national de la recherche scientifique, Unité mixte de recherche 7258, Centre de Recherche en Cancérologie de Marseille, Marseille, France; and.

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April 2016

PDL1 expression is an independent prognostic factor in localized GIST.

Oncoimmunology 2015 May 3;4(5):e1002729. Epub 2015 Feb 3.

Department of Molecular Oncology; Institut Paoli-Calmettes; Centre de Recherche en Cancérologie de Marseille ; UMR1068 Inserm; Marseille, France.

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May 2015

Prediction of early breast cancer metastasis from DNA microarray data using high-dimensional cox regression models.

Cancer Inform 2015 5;14(Suppl 2):129-38. Epub 2015 May 5.

Département de la Recherche Clinique et de l'Innovation, Unité de Biostatistique et de Méthodologie, Institut Paoli-Calmettes, Marseille, France.

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May 2015

The E2F4 prognostic signature is also predictive of the pathological response of breast cancer to chemotherapy.

Breast Cancer Res 2015 Apr 10;17:54. Epub 2015 Apr 10.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, UMR1068 Inserm, 232 boulevard de Sainte-Marguerite, 13009, Marseille, France.

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April 2015

Disulfiram (DSF) acts as a copper ionophore to induce copper-dependent oxidative stress and mediate anti-tumor efficacy in inflammatory breast cancer.

Mol Oncol 2015 Jun 21;9(6):1155-68. Epub 2015 Feb 21.

Department of Surgery, Duke University Medical Center, Durham, NC, USA; Duke Cancer Institute, Duke University Medical Center, Durham, NC, USA; Department of Pathology, Duke University Medical Center, Durham, NC, USA. Electronic address:

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June 2015

Prognostic and predictive value of PDL1 expression in breast cancer.

Oncotarget 2015 Mar;6(7):5449-64

Département d'Oncologie Moléculaire, "Equipe labellisée Ligue Contre le Cancer", Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes, INSERM UMR1068, CNRS UMR725, Marseille, France.

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March 2015

Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterization.

Mol Cancer 2014 Oct 2;13:228. Epub 2014 Oct 2.

Department of Molecular Oncology, Centre de Recherche en Cancérologie de Marseille, UMR1068 Inserm, Institut Paoli-Calmettes (IPC), Marseille, France.

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October 2014

The functional landscape of Hsp27 reveals new cellular processes such as DNA repair and alternative splicing and proposes novel anticancer targets.

Mol Cell Proteomics 2014 Dec 2;13(12):3585-601. Epub 2014 Oct 2.

From the ‡Inserm, UMR1068, CRCM, Marseille, F-13009, France; §Institut Paoli-Calmettes, Marseille, F-13009, France; ¶Aix-Marseille Université, F-13284, Marseille, France; ‖CNRS, UMR7258, CRCM, Marseille, F-13009, France;

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December 2014

EndoPredict predicts for the response to neoadjuvant chemotherapy in ER-positive, HER2-negative breast cancer.

Cancer Lett 2014 Dec 10;355(1):70-5. Epub 2014 Sep 10.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes (IPC), UMR1068 Inserm, 13009 Marseille, France.

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December 2014

Poly(ADP-ribose) polymerase 1 (PARP1) overexpression in human breast cancer stem cells and resistance to olaparib.

PLoS One 2014 21;9(8):e104302. Epub 2014 Aug 21.

Institut Paoli-Calmettes, Department of Molecular Pharmacology, Marseille, France; Institut Paoli-Calmettes, Department of Medical Oncology, Marseille, France; Aix-Marseille University, Marseille, France; Centre de Recherche en Cancérologie de Marseille, U1068 INSERM, U7258 CNRS, Marseille, France.

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May 2015

EFA6B antagonizes breast cancer.

Cancer Res 2014 Oct 12;74(19):5493-506. Epub 2014 Aug 12.

Institut de Pharmacologie Moléculaire et Cellulaire, Université de Nice Sophia-Antipolis CNRS UMR7275, Valbonne, France.

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October 2014

ESPL1 is a candidate oncogene of luminal B breast cancers.

Breast Cancer Res Treat 2014 Aug 3;147(1):51-9. Epub 2014 Aug 3.

Department of Molecular Oncology, U1068 Inserm, Institut Paoli-Calmettes (IPC), Marseille, France.

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August 2014

Brief reports: A distinct DNA methylation signature defines breast cancer stem cells and predicts cancer outcome.

Stem Cells 2014 Nov;32(11):3031-6

CRCM, Molecular Oncology, "Equipe labellisée Ligue Contre le Cancer," Inserm, U1068, Marseille, France; Institut Paoli-Calmettes, Marseille, France; Aix-Marseille Université, Marseille, France; CNRS, UMR7258, Marseille, France.

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November 2014

Genomic profiling of inflammatory breast cancer: a review.

Breast 2014 Oct 4;23(5):538-45. Epub 2014 Jul 4.

Translational Cancer Research Unit, GZA Hospitals Sint-Augustinus, Wilrijk, Belgium; Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp, Belgium; Department of Oncology, KU Leuven, Leuven, Belgium. Electronic address:

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October 2014

ALDH1-positive cancer stem cells predict engraftment of primary breast tumors and are governed by a common stem cell program.

Cancer Res 2013 Dec 18;73(24):7290-300. Epub 2013 Oct 18.

Authors' Affiliations: INSERM, U1068, CRCM, Molecular Oncology, Institut Paoli-Calmettes, Biopathology, Aix-Marseille Univ, UM 105, F-13284, Départements d'Oncologie Médicale, Chirugie oncologique, and Radiologie, Institut Paoli-Calmettes, Marseille; and Plateforme ARN interference PArI, CEA SACLAY, Gif-sur-Yvette, France.

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December 2013

The histone deacetylase inhibitor abexinostat induces cancer stem cells differentiation in breast cancer with low Xist expression.

Clin Cancer Res 2013 Dec 18;19(23):6520-31. Epub 2013 Oct 18.

Authors' Affiliations: Institut national de la santé et de la recherche medicale (INSERM), CRCM, U1068, Laboratoire d'Oncologie Moléculaire; Département de Biopathologie, Institut Paoli-Calmettes; Aix Marseille Université, F-13007; CNRS, CRCM, 7258; INSERM, CRCM, U1068, TrGET, Marseille; and Institut de Recherches Internationales Servier, Paris, France.

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December 2013

Difference in therapeutic response between basal and nonbasal triple-negative breast cancers.

Oncologist 2013 19;18(9):1060-1. Epub 2013 Aug 19.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, Institut Paoli-Calmettes, UMR1068 Inserm; Marseille, France;

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September 2014

Gene expression profiling of solitary fibrous tumors.

PLoS One 2013 29;8(5):e64497. Epub 2013 May 29.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille (CRCM), Institut Paoli-Calmettes (IPC), UMR1068 Inserm, Marseille, France.

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January 2014

8q24 Cancer risk allele associated with major metastatic risk in inflammatory breast cancer.

PLoS One 2012 29;7(5):e37943. Epub 2012 May 29.

Centre de Recherche en Cancérologie de Marseille, Department of Molecular Oncology, Institut Paoli-Calmettes, Marseille, France.

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October 2012

Down-regulation of ECRG4, a candidate tumor suppressor gene, in human breast cancer.

PLoS One 2011 16;6(11):e27656. Epub 2011 Nov 16.

Département d'Oncologie Moléculaire, Centre de Recherche en Cancérologie de Marseille, UMR891 INSERM and Institut Paoli-Calmettes Marseille, Marseille, France.

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March 2012

Gene expression profiling of breast tumor cell lines to predict for therapeutic response to microtubule-stabilizing agents.

Breast Cancer Res Treat 2012 Apr 27;132(3):1035-47. Epub 2011 Jul 27.

Département de Pharmacologie Moléculaire and U891 INSERM, Centre de Recherche En Cancérologie de Marseille, Institut Paoli-Calmettes, Marseille, France.

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April 2012

Kinome expression profiling and prognosis of basal breast cancers.

Mol Cancer 2011 Jul 21;10:86. Epub 2011 Jul 21.

Department of Molecular Oncology, Centre de Recherche en Cancérologie de Marseille, UMR891 Inserm, Institut Paoli-Calmettes, 27 bd Leï Roure, 13009 Marseille, France.

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July 2011

Gene expression profiling and its utility in prediction of local relapse after breast-conserving therapy in early breast cancer.

Cancer Genomics Proteomics 2011 Jul-Aug;8(4):199-209

Department of Molecular Oncology, Marseille Cancer Research Center, Paoli Calmettes Institute, UMR891 Inserm, Marseille, France.

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December 2011