Pascal Chanez

Pascal Chanez

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Pascal Chanez

Publications by authors named "Pascal Chanez"

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Baseline blood eosinophil count as a predictor of treatment response to the licensed dose of mepolizumab in severe eosinophilic asthma.

Respir Med 2019 Nov 3;159:105806. Epub 2019 Nov 3.

Department of Allergy, Hospital La Paz Institute for Health Research (IdiPAZ), CIBER de Enfermedades Respiratorias CIBERES, Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2019.105806DOI Listing
November 2019

Bronchial Epithelial Calcium Metabolism Impairment in Smokers and Chronic Obstructive Pulmonary Disease. Decreased ORAI3 Signaling.

Am J Respir Cell Mol Biol 2019 Oct;61(4):501-511

Department of Respiratory Diseases and Addictology, Hôpital Arnaud de Villeneuve, Centre Hospitalier Universitaire Montpellier, Montpellier, France.

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http://dx.doi.org/10.1165/rcmb.2018-0228OCDOI Listing
October 2019

Efficacy of Intravenous Reslizumab in Oral Corticosteroid-Dependent Asthma.

J Allergy Clin Immunol Pract 2019 Oct 15. Epub 2019 Oct 15.

Department of Respiratory Diseases, Aix-Marseille University, Marseille, France.

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http://dx.doi.org/10.1016/j.jaip.2019.09.036DOI Listing
October 2019

Adverse publicity of serious side effects to healthy volunteers has limited effect on willingness-to-participate in clinical trials.

Clin Trials 2019 Aug 29;16(4):440-442. Epub 2019 Mar 29.

3 Department of Respiratory Diseases, University of Montpellier, CHU Montpellier, Montpellier, France.

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http://dx.doi.org/10.1177/1740774519840268DOI Listing
August 2019

Relationship between gender and survival in a real-life cohort of patients with COPD.

Respir Res 2019 Aug 22;20(1):191. Epub 2019 Aug 22.

Respiratory and Intensive Care Medicine Department, Cochin Hospital, AP-HP and Paris Descartes University (EA 2511), Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1186/s12931-019-1154-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704674PMC
August 2019

Randomized controlled trials of pharmacological treatments to prevent COPD exacerbations: applicability to real-life patients.

BMC Pulm Med 2019 Jul 12;19(1):127. Epub 2019 Jul 12.

Clinique des bronches allergies et sommeil, Aix Marseille Univ, APHM, CIC 9502, 13015, Marseille, France.

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http://dx.doi.org/10.1186/s12890-019-0882-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6625055PMC
July 2019

Goblet cell hyperplasia as a feature of neutrophilic asthma.

Clin Exp Allergy 2019 Jun 27;49(6):781-788. Epub 2019 Feb 27.

Aix Marseille University, INSERM, INRA, C2VN, Marseille, France.

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http://dx.doi.org/10.1111/cea.13359DOI Listing
June 2019

COPD beyond proximal bronchial obstruction: phenotyping and related tools at the bedside.

Eur Respir Rev 2019 Jun 8;28(152). Epub 2019 Jul 8.

Clinique des Bronches, Allergies et Sommeil, Hôpital Nord, Assistance Publique des Hôpitaux de Marseille, Aix Marseille Université, Marseille, France

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http://dx.doi.org/10.1183/16000617.0010-2019DOI Listing
June 2019

KIT as a therapeutic target for non-oncological diseases.

Pharmacol Ther 2019 05 14;197:11-37. Epub 2018 Dec 14.

Aix Marseille Université, INSERM, INRA, C2VN, Marseille, France; Clinique des Bronches, Allergies et Sommeil, Hôpital Nord, AP-HM, Marseille, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01637258183023
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http://dx.doi.org/10.1016/j.pharmthera.2018.12.008DOI Listing
May 2019

Severe asthma treated by bronchial thermoplasty: A success not due to the small airways?

Respirology 2019 May 29;24(5):402-403. Epub 2019 Jan 29.

Université de Montpellier, PhyMedExp, INSERM, CNRS, CHU de Montpellier, Department of Respiratory Diseases, Montpellier, France.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/resp.13481
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http://dx.doi.org/10.1111/resp.13481DOI Listing
May 2019

Cypress Pollinosis: from Tree to Clinic.

Clin Rev Allergy Immunol 2019 Apr;56(2):174-195

Armand Trousseau Children Hospital, AP-HP, Biochemistry Department, Allergy and Environment Research team, Paris, France.

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http://dx.doi.org/10.1007/s12016-017-8602-yDOI Listing
April 2019

Early decreases in blood eosinophil levels with reslizumab.

J Allergy Clin Immunol 2019 Apr 14;143(4):1653-1655. Epub 2019 Jan 14.

Allergy, Asthma, and Pulmonary Research, Boys Town National Research Hospital, Omaha, Neb.

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http://dx.doi.org/10.1016/j.jaci.2018.12.997DOI Listing
April 2019

Haplotypes Are Differentially Associated with Asthmatic Features.

Front Immunol 2018 23;9:278. Epub 2018 Feb 23.

UMR7268 Anthropologie bio-culturelle, Droit, Ethique et Santé (ADES), "Biologie des Groupes Sanguins", Aix Marseille Université, CNRS, Établissement Français du Sang (EFS), Marseille, France.

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http://dx.doi.org/10.3389/fimmu.2018.00278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5829031PMC
March 2019

Randomised controlled trials in severe asthma: selection by phenotype or stereotype.

Eur Respir J 2019 Feb 7;53(2). Epub 2019 Feb 7.

Aix Marseille Univ, APHM, CIC 9502, Clinique des bronches, allergies et sommeil, Marseille, France.

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http://dx.doi.org/10.1183/13993003.02187-2018DOI Listing
February 2019

Reply to Upham: The Bronchial Epithelial Secretory IgA System in Asthma.

Am J Respir Crit Care Med 2018 11;198(9):1236-1238

1 Université Catholique de Louvain Brussels, Belgium.

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http://dx.doi.org/10.1164/rccm.201806-1128LEDOI Listing
November 2018

Bronchial Thermoplasty in Severe Asthma: Best Practice Recommendations from an Expert Panel.

Respiration 2018;95(5):289-300. Epub 2018 Apr 17.

MAHSC, University of Manchester and Manchester Foundation Trust, Manchester, United Kingdom.

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http://dx.doi.org/10.1159/000488291DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492603PMC
October 2018

Relationship between blood eosinophils, clinical characteristics, and mortality in patients with COPD.

Int J Chron Obstruct Pulmon Dis 2017 20;12:1819-1824. Epub 2017 Jun 20.

Respiratory and Intensive Care Medicine Dpt, Cochin Hospital, AP-HP and Paris Descartes University (EA2511), Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.2147/COPD.S129787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490470PMC
April 2018

Asthma, COPD, and overlap in a national cohort: ACO on a gradient.

J Allergy Clin Immunol 2018 04 31;141(4):1516-1518. Epub 2018 Jan 31.

INSERM U 1046, Arnaud de Villeneuve Hospital, Crastes de Paulet Building, Montpellier, France; Department of Medical Information, Montpellier University Hospitals, La Colombière Hospital, Montpellier Cedex, France; Alexander Grothendieck Institut at Montpellier, CNRS, Montpellier University, Montpellier, France.

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http://dx.doi.org/10.1016/j.jaci.2017.11.049DOI Listing
April 2018

Lung development, regeneration and plasticity: From disease physiopathology to drug design using induced pluripotent stem cells.

Pharmacol Ther 2018 03 4;183:58-77. Epub 2017 Oct 4.

Department of Respiratory Diseases, Hôpital Arnaud de Villeneuve, Montpellier F34000, France; Université de MONTPELLIER, UFR de Médecine, Montpellier F34000, France; INSERM, U1046, PhyMedExp, Montpellier F34000, France. Electronic address:

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http://dx.doi.org/10.1016/j.pharmthera.2017.10.002DOI Listing
March 2018

Radiological abnormalities following bronchial thermoplasty: is the pathophysiology understood?

Eur Respir J 2017 12 7;50(6). Epub 2017 Dec 7.

Dept of Pneumology A, Bichat Claude Bernard Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.

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http://dx.doi.org/10.1183/13993003.02067-2017DOI Listing
December 2017

Mortality: a neglected outcome in OCS-treated severe asthma.

Eur Respir J 2017 11 30;50(5). Epub 2017 Nov 30.

Assistance Publique - Hôpitaux de Marseille, Clinique des bronches, allergies et sommeil, Hôpital Nord, Marseille, France

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http://dx.doi.org/10.1183/13993003.01486-2017DOI Listing
November 2017

Mepolizumab for Eosinophilic Chronic Obstructive Pulmonary Disease.

N Engl J Med 2017 10 11;377(17):1613-1629. Epub 2017 Sep 11.

From the Respiratory Medicine Unit and Oxford Respiratory Biomedical Research Centre, Nuffield Department of Medicine, University of Oxford, Oxford (I.D.P.), and Clinical Statistics, GlaxoSmithKline, Uxbridge (B.M.) - both in the United Kingdom; the Department of Respiratory Medicine and CIC Nord, Aix-Marseille University, Marseille, France (P.C.); the Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia (G.J.C.); the Department of Pulmonary Medicine and Tuberculosis, University of Groningen and University Medical Center Groningen, Groningen, the Netherlands (H.A.M.K.); the Pulmonary Department, Mainz University Hospital, Mainz, Germany (S.K.); the Division of Pulmonary, Allergy, and Critical Care Medicine, Duke University, Durham (N.L.), and the Respiratory Medical Franchise (F.C.A.) and the Respiratory Therapeutic Area (E.S.B., S.S.H., D.B.R., S.W.Y.), GlaxoSmithKline, Research Triangle Park - all in North Carolina; the Department of Pneumology, Centre Hospitalier Universitaire-Université Catholique de Louvain, Namur, Namur, Belgium (J.-B.M.); the Division of Allergology and Respiratory Medicine, Showa University School of Medicine, Tokyo (H.S.); and the Department of Medicine, University of Pittsburgh, Pittsburgh (F.C.S.).

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http://dx.doi.org/10.1056/NEJMoa1708208DOI Listing
October 2017

Impact of current cough on health-related quality of life in patients with COPD.

Int J Chron Obstruct Pulmon Dis 2016 13;11:2091-2097. Epub 2016 Sep 13.

Department of Respiratory Diseases, Cochin Hospital, AP-HP and University Paris Descartes, Sorbonne Paris Cité, Paris.

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http://dx.doi.org/10.2147/COPD.S106883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5028084PMC
August 2017

Club cell secretory protein serum concentration is a surrogate marker of small-airway involvement in asthmatic patients.

J Allergy Clin Immunol 2017 08 17;140(2):581-584. Epub 2017 Jan 17.

Department of Respiratory Diseases, Montpellier University Hospital, Montpellier, France; PhyMedExp, University of Montpellier, INSERM U1046, Montpellier University Hospital, Montpellier, France; APARD: Association pour l'Assistance et la Réhabilitation à Domicile, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.09.063DOI Listing
August 2017

Novel Treatments for Airway Disease

N Engl J Med 2017 08 10;377(6):595-6. Epub 2017 Aug 10.

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http://dx.doi.org/10.1056/NEJMc1708004DOI Listing
August 2017

Novel Treatments for Airway Disease.

N Engl J Med 2017 08;377(6):595-6

Aix Marseille Université, Marseille, France

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http://dx.doi.org/10.1056/NEJMc1708004DOI Listing
August 2017

How effective is bronchial thermoplasty for severe asthma in clinical practice?

Eur Respir J 2017 08 31;50(2). Epub 2017 Aug 31.

Inserm U1067 and CNRS UMR7733, Dept of Respiratory Diseases, APHM Aix-Marseille University, Marseille, France.

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http://dx.doi.org/10.1183/13993003.01140-2017DOI Listing
August 2017

Severe eosinophilic asthma: a roadmap to consensus.

Eur Respir J 2017 05 1;49(5). Epub 2017 May 1.

Dept of Clinical and Experimental Sciences, University of Southampton, Southampton, UK

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http://dx.doi.org/10.1183/13993003.00634-2017DOI Listing
May 2017

Managing asthma in the era of biological therapies.

Lancet Respir Med 2017 05 24;5(5):376-378. Epub 2017 Apr 24.

Département de Pneumologie et Addictologie-Hôpital Arnaud de Villeneuve-Montpellier, France; PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(17)30124-8DOI Listing
May 2017

Effectiveness of bronchial thermoplasty in patients with severe refractory asthma: Clinical and histopathologic correlations.

J Allergy Clin Immunol 2017 Apr 5;139(4):1176-1185. Epub 2016 Sep 5.

Inserm UMR1152, Physiopathology and Epidemiology of Respiratory Diseases, Paris, France; Paris Diderot University, Faculty of Medicine, Bichat campus, Paris, France; Laboratory of Excellence, INFLAMEX, Université Sorbonne Paris Cité, and DHU FIRE, Paris, France; Department of Pneumology A, Bichat-Claude Bernard University Hospital, Paris, France; Assistance Publique des Hôpitaux de Paris, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.08.009DOI Listing
April 2017

Switch of noninvasive ventilation (NIV) to continuous positive airway pressure (CPAP) in patients with obesity hypoventilation syndrome: a pilot study.

BMC Pulm Med 2017 03 14;17(1):50. Epub 2017 Mar 14.

Clinique des Bronches, Allergies et du Sommeil, Assistance Publique Hôpitaux de Marseille, France et INSERM U1067, CNRS UMR 7333 Aix Marseille Université, 13015, Marseille, France.

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http://dx.doi.org/10.1186/s12890-017-0391-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348845PMC
March 2017

Early computed tomography modifications following bronchial thermoplasty in patients with severe asthma.

Eur Respir J 2017 03 15;49(3). Epub 2017 Mar 15.

Dept of Pneumology A, Bichat Claude Bernard Hospital Assistance Publique-Hôpitaux de Paris, Paris, France.

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http://dx.doi.org/10.1183/13993003.01565-2016DOI Listing
March 2017

A place for Apnea Hypopnea Index telemonitoring in preventing heart failure exacerbation?

Sleep Med 2017 01 5;29:18-19. Epub 2016 Nov 5.

Clinique des Bronches, Allergies et du Sommeil, Assistance Publique Hôpitaux de Marseille, France et INSERM U1067, CNRS UMR 7333 Aix Marseille Université, France.

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http://dx.doi.org/10.1016/j.sleep.2016.10.011DOI Listing
January 2017

Bronchial Epithelial Cells from Asthmatic Patients Display Less Functional HLA-G Isoform Expression.

Front Immunol 2017 23;8. Epub 2017 Jan 23.

Etablissement Français du Sang Alpes Méditerranée, Marseille, France; Aix-Marseille Univ, CNRS, EFS, ADES, "Biologie des Groupes Sanguins", Marseille, France.

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http://dx.doi.org/10.3389/fimmu.2017.00006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5333864PMC
January 2017

[How to consider triggers and comorbid conditions in severe asthma in adults].

Presse Med 2016 Nov 18;45(11):1030-1042. Epub 2016 Aug 18.

AP-HM, Aix-Marseille université, département des maladies respiratoires, UMR 7333 CNRS, Inserm U1067, 13015 Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.lpm.2016.07.020DOI Listing
November 2016

Rising total costs and mortality rates associated with admissions due to COPD exacerbations.

Respir Res 2016 11 14;17(1):149. Epub 2016 Nov 14.

PhyMedExp, University of Montpellier, INSERM U1046, CNRS UMR 9214, Montpellier hospital, Montpellier, France.

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http://dx.doi.org/10.1186/s12931-016-0469-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5109821PMC
November 2016

Hospitalizations for COPD Exacerbations: Trends and Determinants of Death.

COPD 2015 11;12(6):621-7. Epub 2015 Aug 11.

b INSERM U1046, Université Montpellier 1 et 2 , Hôpital Arnaud de Villeneuve, CHU Montpellier, France.

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http://dx.doi.org/10.3109/15412555.2015.1007931DOI Listing
September 2016

Long-term Efficacy and Safety of Mepolizumab in Patients With Severe Eosinophilic Asthma: A Multi-center, Open-label, Phase IIIb Study.

Clin Ther 2016 Sep 21;38(9):2058-2070.e1. Epub 2016 Aug 21.

Respiratory Therapeutic Area, GlaxoSmithKline, Research Triangle Park, North Carolina.

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http://dx.doi.org/10.1016/j.clinthera.2016.07.010DOI Listing
September 2016

New sociology for better understanding severe eosinophilic asthma: introducing the SOCS family.

Eur Respir J 2016 09;48(3):608-10

UMR INSERM 1067/CNRS 7333, Marseille, France Aix-Marseille Université, Marseille, France APHM (Assistance Publique Hôpitaux de Marseille), Clinique des Bronches, de l'Allergie et du Sommeil, Hôpital Nord, Marseille, France.

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http://dx.doi.org/10.1183/13993003.01240-2016DOI Listing
September 2016

Assessment of nanoparticles and metal exposure of airport workers using exhaled breath condensate.

J Breath Res 2016 07 13;10(3):036006. Epub 2016 Jul 13.

University of Grenoble Alpes, F-38000 France. Medical Biology Laboratory (LBM), NanoSafety Platform (SPNS), CEA, 17 rue des martyrs, F-38054 Grenoble, France.

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http://dx.doi.org/10.1088/1752-7155/10/3/036006DOI Listing
July 2016

Airway lipoxin A4/formyl peptide receptor 2-lipoxin receptor levels in pediatric patients with severe asthma.

J Allergy Clin Immunol 2016 06 11;137(6):1796-1806. Epub 2016 Mar 11.

Institute of Biomedicine and Molecular Immunology, Unit of Immunopathology and Pharmacology of the Respiratory System, Italian National Research Council, Palermo, Italy.

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http://dx.doi.org/10.1016/j.jaci.2015.11.045DOI Listing
June 2016

Bronchial epithelium in children: a key player in asthma.

Eur Respir Rev 2016 Jun;25(140):158-69

UMR Inserm U1067 CNRS 7333, Aix Marseille University, Marseille, France.

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http://dx.doi.org/10.1183/16000617.0101-2015DOI Listing
June 2016

Omalizumab: a treatment for severe asthma in real life?

Rev Port Pneumol (2006) 2015 May-Jun;21(3):111-2

Département des Maladies Respiratoires, AP-HM, INSERM CNRS U 1067, UMR7733, Aix Marseille Université, Marseille, France. Electronic address:

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http://dx.doi.org/10.1016/j.rppnen.2015.04.002DOI Listing
April 2016

Modified Medical Research Council scale vs Baseline Dyspnea Index to evaluate dyspnea in chronic obstructive pulmonary disease.

Int J Chron Obstruct Pulmon Dis 2015 18;10:1663-72. Epub 2015 Aug 18.

Service de Pneumologie, Groupe Hospitalier Cochin Broca Hotel Dieu, AP HP et Université René Descartes, Paris, France.

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http://dx.doi.org/10.2147/COPD.S82408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4547644PMC
April 2016

The lung microbiome: the perfect culprit for COPD exacerbations?

Eur Respir J 2016 Apr;47(4):1034-6

Dept of Respiratory Diseases APHM, INSERM CNRS U 1067, UMR7333, Aix-Marseille University, Marseille France

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http://dx.doi.org/10.1183/13993003.00270-2016DOI Listing
April 2016

Asthma phenotypes and IgE responses.

Eur Respir J 2016 Jan 17;47(1):304-19. Epub 2015 Dec 17.

Institut de Recherche Expérimentale et Clinique, Pôle de Pneumologie, Université catholique de Louvain, Brussels and Walloon Institute for Excellence in Lifesciences and Biotechnology (WELBIO), Belgium Dept of Chest Medicine, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium

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http://erj.ersjournals.com/content/erj/47/1/304.full.pdf
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http://erj.ersjournals.com/lookup/doi/10.1183/13993003.01824
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http://dx.doi.org/10.1183/13993003.01824-2014DOI Listing
January 2016

Effects of Bronchial Thermoplasty on Airway Smooth Muscle and Collagen Deposition in Asthma.

Ann Am Thorac Soc 2015 Nov;12(11):1612-8

1 Institut universitaire de cardiologie et de pneumologie de Québec, Université Laval, Québec, Québec, Canada; and.

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http://dx.doi.org/10.1513/AnnalsATS.201504-208OCDOI Listing
November 2015

Reply: Increased Mortality during Bleomycin-induced Pulmonary Fibrosis due to Low Endogenous Activated Protein C Levels.

Am J Respir Crit Care Med 2015 Nov;192(10):1259-60

3 APHM Marseille, France and.

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http://dx.doi.org/10.1164/rccm.201507-1307LEDOI Listing
November 2015

[Heroin makes asthma difficult and sometimes nearly fatal].

Presse Med 2015 Oct 31;44(10):1072-5. Epub 2015 Aug 31.

Clinique des bronches, allergies et du sommeil, Assistance Publique Hôpitaux de Marseille, Aix-Marseille université, Inserm 1067, CNRS UFR 7333, hôpital Nord, chemin des Bourrely, 13915 Marseille cedex 20, France.

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http://dx.doi.org/10.1016/j.lpm.2015.07.020DOI Listing
October 2015

Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells.

Science 2015 Sep;349(6252):1106-10

Laboratory of Immunoregulation, VIB Inflammation Research Center, Ghent, Belgium. Department of Internal Medicine, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1126/science.aac6623DOI Listing
September 2015

External Validity of Randomized Controlled Trials in Severe Asthma.

Am J Respir Crit Care Med 2015 Jul;192(2):259-61

1 Assistance Publique-Hôpitaux de Marseille Marseille, France.

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http://dx.doi.org/10.1164/rccm.201502-0391LEDOI Listing
July 2015

Supplementing defect in club cell secretory protein attenuates airway inflammation in COPD.

Chest 2015 Jun;147(6):1467-1476

Département de Pneumologie et Addictologie, Hôpital Arnaud de Villeneuve, CHU Montpellier; INSERM U1046, Université Montpellier 1 et 2, Hôpital Arnaud de Villeneuve, CHU Montpellier, France. Electronic address:

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http://dx.doi.org/10.1378/chest.14-1174DOI Listing
June 2015

Clinically relevant outcome measures for new therapies of asthma using pharmaceutical and biologic agents.

Curr Opin Allergy Clin Immunol 2015 Jun;15(3):213-9

aQuebec Heart and Lung Institute, Laval University, Québec City, Quebec, Canada bDépartement des Maladies Respiratoires APHM, Laboratoire INSERM CNRS U, 1067, UMR7333, Aix-Marseille University, Marseille, France.

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http://dx.doi.org/10.1097/ACI.0000000000000165DOI Listing
June 2015

Club cells and CC16: another "smoking gun"? (With potential bullets against COPD).

Eur Respir J 2015 Jun;45(6):1519-20

U1046 INSERM, UMR9214 CNRS, Montpellier University, Montpellier, France Dept of Respiratory Diseases, CHRU Montpellier, Montpellier, France

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http://dx.doi.org/10.1183/09031936.00010515DOI Listing
June 2015

Reply: reduction of airway smooth muscle mass by bronchial thermoplasty in patients with severe asthma.

Am J Respir Crit Care Med 2015 May;191(10):1208-9

1 Physiopathologie et Epidémiologie des Maladies Respiratoires Paris, France.

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http://dx.doi.org/10.1164/rccm.201503-0500LEDOI Listing
May 2015

We should prohibit warfarin in idiopathic pulmonary fibrosis.

Am J Respir Crit Care Med 2015 Apr;191(8):958-60

1 Aix Marseille Université Marseille, France.

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http://dx.doi.org/10.1164/rccm.201412-2281LEDOI Listing
April 2015

Body mass index and comorbidities in adult severe asthmatics.

Biomed Res Int 2014 28;2014:607192. Epub 2014 May 28.

Département de Pneumoallergology, AP-HM, Laboratoire d'Immunologie, Inserm CNRS U 1067, UMR7333, Aix Marseille Université, 13009 Marseille, France.

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http://dx.doi.org/10.1155/2014/607192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058470PMC
February 2015

Persistent severe hypereosinophilic asthma is not associated with airway remodeling.

Respir Med 2015 Feb 3;109(2):180-7. Epub 2015 Jan 3.

Department of Respiratory Disease, CHU Montpellier, Montpellier, France; INSERM U1046, Université Montpellier I et II, Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.rmed.2014.12.008DOI Listing
February 2015

Real-life use of long-acting antimuscarinic agents following their approval for COPD treatment.

Eur Respir J 2015 Jan 30;45(1):260-2. Epub 2014 Oct 30.

Service de Pneumologie, Hôpital Cochin, AP-HP and Université Paris Descartes (EA2511), Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1183/09031936.00131614DOI Listing
January 2015

Asthma: still a promising future?

Eur Respir Rev 2014 Dec;23(134):405-7

Respiratory Medicine APHM, INSERM U1067, Aix-Marseille University, Marseille, France. Service de Pneumologie, Université Paris-Sud, AP-HP, Hôpital Bicêtre, Inserm U999, Le Kremlin Bicêtre, France.

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http://err.ersjournals.com/cgi/doi/10.1183/09059180.00009614
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http://dx.doi.org/10.1183/09059180.00009614DOI Listing
December 2014

Bronchial thermoplasty: a new therapeutic option for the treatment of severe, uncontrolled asthma in adults.

Eur Respir Rev 2014 Dec;23(134):510-8

Dept of Respiratory Medicine, Bichat APHP, U700 INSERM University Hospitals Dept, Diderot University, Paris, France Dept of Respiratory Medicine, APHM, INSERM U1067 CNRS UMR 7333, Aix Marseille University, Marseille, FranceResearch Centre at the Institute of Cardiology and Respiratory Medicine, Laval University, Quebec, QC, CanadaDept of Radiology, Avicenne Public Hospital, Bobigny, France Dept of Respiratory Medicine, Ghent University Hospital, Ghent University, Ghent, BelgiumDept of Respiratory Medicine, Liege University Hospital, GIGAI3 Research Group, University of Liège, Liège, BelgiumDept of Respiratory Medicine, HUG Geneva, SwitzerlandBoth authors contributed equally

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http://dx.doi.org/10.1183/09059180.00005114DOI Listing
December 2014

Prognostic value of cluster analysis of severe asthma phenotypes.

J Allergy Clin Immunol 2014 Nov 27;134(5):1043-50. Epub 2014 Jun 27.

Département des Maladies Respiratoires, AP-HM, UMR7733, Aix-Marseille Université, Marseille, France; Laboratoire INSERM CNRS U 1067, UMR7733, Aix-Marseille Université, Marseille, France.

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http://dx.doi.org/10.1016/j.jaci.2014.04.038DOI Listing
November 2014

Mepolizumab treatment in patients with severe eosinophilic asthma.

N Engl J Med 2014 Sep 8;371(13):1198-207. Epub 2014 Sep 8.

From the Respiratory Therapeutic Area Unit, GlaxoSmithKline, Research Triangle Park, NC (H.G.O., L.E.K., S.W.Y.); Johns Hopkins Asthma and Allergy Center, Baltimore (M.C.L.); Respiratory Medicine Unit, Nuffield Department of Medicine, University of Oxford, Oxford (I.D.P.), and Clinical Statistics, GlaxoSmithKline, Stockley Park, Middlesex (O.N.K.) - both in the United Kingdom; the Department of Respiratory Medicine, Ghent University Hospital, Ghent, Belgium (G.G.B.); the Lung Centre, Institute for Heart and Lung Health, Vancouver, BC, Canada (J.M.F.); the Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy (A.C.); and Assistance Publique-Hôpitaux de Paris, Département Hospitalo-Universitaire Thorax Innovation, Service de Pneumologie, Hôpital Bicêtre, Université Paris-Sud, and INSERM Unité Mixte de Recherche 999, Le Kremlin-Bicêtre (M.H.), and Unités Mixtes de Recherche INSERM Unité 1067 Centre Nationale de la Recherche Scientifique 7733, Aix-Marseille Université, Department of Respiratory Diseases and Clinical Investigation Center, Assistance Publique-Hôpitaux de Marseille, Hôpital Nord, Marseille (P.C.) - both in France.

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http://dx.doi.org/10.1056/NEJMoa1403290DOI Listing
September 2014

Long-term prognostic value of component-resolved diagnosis in infants and toddlers with peanut allergy.

Pediatr Allergy Immunol 2014 Aug 18;25(5):506-8. Epub 2014 Mar 18.

Department of Pediatrics, Allergy and Clinical Immunology Division, Centre Hospitalier Universitaire Sainte-Justine, Montreal, Canada; Department of Medicine, Allergy and Clinical Immunology Unit, Centre Hospitalier de l'Université de Montréal, Montreal, Canada.

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http://dx.doi.org/10.1111/pai.12216DOI Listing
August 2014

Long-acting muscarinic receptor antagonists for the treatment of chronic airway diseases.

Ther Adv Chronic Dis 2014 Mar;5(2):85-98

Respiratory Department, AP-HM, Inserm CNRS U 1067, UMR7333, Aix Marseille Université, Marseille, France.

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http://dx.doi.org/10.1177/2040622313518227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3926345PMC
March 2014

Impact of gender on COPD expression in a real-life cohort.

Respir Res 2014 Feb 17;15:20. Epub 2014 Feb 17.

Service de Pneumologie et Soins Intensifs Respiratoires, Groupe Hospitalier Cochin Broca Hôtel-Dieu, AP-HP and Université Paris Descartes, Sorbonne Paris Cité, Paris, France.

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http://dx.doi.org/10.1186/1465-9921-15-20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931914PMC
February 2014