Publications by authors named "Parmjit S Jat"

32Publications

Highly infectious prions are not directly neurotoxic.

Proc Natl Acad Sci U S A 2020 Sep 8;117(38):23815-23822. Epub 2020 Sep 8.

Medical Research Council Prion Unit at University College London (UCL), UCL Institute of Prion Diseases, London W1W 7FF, United Kingdom

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http://dx.doi.org/10.1073/pnas.2007406117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7525444PMC
September 2020

Tumour suppressors and cellular senescence.

IUBMB Life 2014 Dec 29;66(12):812-22. Epub 2014 Dec 29.

Department of Neurodegenerative Disease and MRC Prion Unit, UCL Institute of Neurology, Queen Square, London, WC1N 3BG.

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http://dx.doi.org/10.1002/iub.1335DOI Listing
December 2014

Identification of clinical target areas in the brainstem of prion-infected mice.

Neuropathol Appl Neurobiol 2015 Aug 23;41(5):613-30. Epub 2015 Apr 23.

MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1111/nan.12189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949711PMC
August 2015

Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence.

PLoS Genet 2014 Sep 25;10(9):e1004642. Epub 2014 Sep 25.

Institute for Cell and Molecular Biosciences, Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, United Kingdom.

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http://dx.doi.org/10.1371/journal.pgen.1004642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177746PMC
September 2014

Cellular senescence and aging: the role of B-MYB.

Aging Cell 2014 Oct 1;13(5):773-9. Epub 2014 Jul 1.

Department of Neurodegenerative Disease and MRC Prion Unit, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK.

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http://dx.doi.org/10.1111/acel.12242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331756PMC
October 2014

Friend or foe: emerging role of nuclear factor kappa-light-chain-enhancer of activated B cells in cell senescence.

Onco Targets Ther 2013 Sep 4;6:1221-9. Epub 2013 Sep 4.

Department of Neurodegenerative Disease and MRC Prion Unit, UCL institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.2147/OTT.S36160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772761PMC
September 2013

Receptor-mediated endocytosis and endosomal acidification is impaired in proximal tubule epithelial cells of Dent disease patients.

Proc Natl Acad Sci U S A 2013 Apr 9;110(17):7014-9. Epub 2013 Apr 9.

Academic Endocrine Unit, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, United Kingdom.

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http://dx.doi.org/10.1073/pnas.1302063110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637698PMC
April 2013

Deciphering the role of nuclear factor-κB in cellular senescence.

Aging (Albany NY) 2011 Oct;3(10):913-9

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London, UK.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229968PMC
http://dx.doi.org/10.18632/aging.100390DOI Listing
October 2011

An RNA interference screen for identifying downstream effectors of the p53 and pRB tumour suppressor pathways involved in senescence.

BMC Genomics 2011 Jul 8;12:355. Epub 2011 Jul 8.

Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK.

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http://dx.doi.org/10.1186/1471-2164-12-355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161017PMC
July 2011

Dissecting the transcriptional networks underlying breast cancer: NR4A1 reduces the migration of normal and breast cancer cell lines.

Breast Cancer Res 2010 19;12(4):R51. Epub 2010 Jul 19.

University of Oxford Branch, Ludwig Institute for Cancer Research, Old Road Campus, Off Roosevelt Drive, Oxford OX3 7DQ, UK.

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http://dx.doi.org/10.1186/bcr2610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2949640PMC
March 2011

Simian virus 40 large T antigen disrupts genome integrity and activates a DNA damage response via Bub1 binding.

J Virol 2009 Jan 15;83(1):117-27. Epub 2008 Oct 15.

Hillman Cancer Center, Research Pavilion Suite 1.8, 5117 Centre Avenue, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1128/JVI.01515-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2612341PMC
January 2009

Preparation of monoclonal antibodies against the spindle checkpoint kinase Bub1.

Hybridoma (Larchmt) 2007 Jun;26(3):140-7

Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, London, United Kingdom.

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http://dx.doi.org/10.1089/hyb.2007.003DOI Listing
June 2007

Surveillance mechanism linking Bub1 loss to the p53 pathway.

Proc Natl Acad Sci U S A 2007 May 8;104(20):8334-9. Epub 2007 May 8.

Molecular Virology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15213, USA.

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http://dx.doi.org/10.1073/pnas.0703164104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895950PMC
May 2007

Retrovirus-mediated conditional immortalization and analysis of established cell lines of osteoclast precursor cells.

Biochem Biophys Res Commun 2006 Nov 18;350(1):97-104. Epub 2006 Sep 18.

Laboratory of Molecular Oncology, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan.

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http://dx.doi.org/10.1016/j.bbrc.2006.09.020DOI Listing
November 2006

Glucose induces increases in levels of the transcriptional repressor Id2 via the hexosamine pathway.

Am J Physiol Endocrinol Metab 2006 Apr 18;290(4):E599-606. Epub 2005 Oct 18.

Department of Biochemistry and Molecular Biology, Guys Hospital, Kings College, London, United Kingdom.

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http://dx.doi.org/10.1152/ajpendo.00242.2005DOI Listing
April 2006

Loss of c-abl facilitates anchorage-independent growth of p53- and RB- deficient primary mouse embryonic fibroblasts.

Oncogene 2004 Nov;23(52):8527-34

Laboratory of Molecular Oncology, Osaka Bioscience Institute, 6-2-4 Furuedai, Suita, Osaka 565-0874, Japan.

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http://dx.doi.org/10.1038/sj.onc.1207894DOI Listing
November 2004

Order of genetic events is critical determinant of aberrations in chromosome count and structure.

Genes Chromosomes Cancer 2004 Aug;40(4):298-306

Institute of Human Genetics, Technical University, Munich, Germany.

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http://dx.doi.org/10.1002/gcc.20051DOI Listing
August 2004

Simian virus 40 large T antigen targets the spindle assembly checkpoint protein Bub1.

Proc Natl Acad Sci U S A 2004 Jan 19;101(4):947-52. Epub 2004 Jan 19.

Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, Courtauld Building, 91 Riding House Street, London W1W 7BS, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0308006100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC327122PMC
January 2004

Differential proteome analysis of replicative senescence in rat embryo fibroblasts.

Mol Cell Proteomics 2002 Apr;1(4):280-92

Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, Courtauld Building, 91 Riding House Street, London W1W 7BS, United Kingdom.

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http://dx.doi.org/10.1074/mcp.m100028-mcp200DOI Listing
April 2002

Identification of novel candidates for replicative senescence by functional proteomics.

Oncogene 2002 Jun;21(28):4403-13

Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, Courtauld Building, 91 Riding House Street, London W1W 7BS, UK.

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http://dx.doi.org/10.1038/sj.onc.1205525DOI Listing
June 2002

Differential protein expression, DNA binding and interaction with SV40 large tumour antigen implicate the p63-family of proteins in replicative senescence.

Oncogene 2002 Feb;21(7):981-9

Ludwig Institute for Cancer Research, Royal Free and University College School of Medicine, Courtauld Building, 91 Riding House Street, London W1W 7BS, UK.

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http://dx.doi.org/10.1038/sj.onc.1205253DOI Listing
February 2002

Conditional immortalization of growth factor-responsive cardiac endothelial cells from H-2K(b)-tsA58 mice.

Am J Physiol Cell Physiol 2002 Jan;282(1):C67-74

British Heart Foundation Cardiovascular Medicine Unit, National Heart and Lung Institute, London, United Kingdom.

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http://dx.doi.org/10.1152/ajpcell.2002.282.1.C67DOI Listing
January 2002