Parkash S Gill

Parkash S Gill

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Parkash S Gill

Parkash S Gill

Publications by authors named "Parkash S Gill"

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Programmed Death 1 and Programmed Death Ligand 1 Inhibitors in Advanced and Recurrent Urothelial Carcinoma: Meta-analysis of Single-Agent Studies.

Clin Genitourin Cancer 2020 Jan 31. Epub 2020 Jan 31.

USC Institute of Urology and Catherine & Joseph Aresty Department of Urology, University of Southern California, Keck School of Medicine, Los Angeles, CA. Electronic address:

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http://dx.doi.org/10.1016/j.clgc.2020.01.004DOI Listing
January 2020

EPHB4 inhibition activates ER stress to promote immunogenic cell death of prostate cancer cells.

Cell Death Dis 2019 Oct 22;10(11):801. Epub 2019 Oct 22.

Department of Urology, The Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.

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http://dx.doi.org/10.1038/s41419-019-2042-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805914PMC
October 2019

GRP78 regulates CD44v membrane homeostasis and cell spreading in tamoxifen-resistant breast cancer.

Life Sci Alliance 2019 08 15;2(4). Epub 2019 Aug 15.

Department of Biochemistry and Molecular Medicine, University of Southern California, Los Angeles, CA, USA

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http://dx.doi.org/10.26508/lsa.201900377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6696983PMC
August 2019

EPHB4 is a therapeutic target in AML and promotes leukemia cell survival via AKT.

Blood Adv 2017 Sep 28;1(20):1635-1644. Epub 2017 Aug 28.

Division of Hematology, Department of Medicine, USC Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://www.bloodadvances.org/lookup/doi/10.1182/bloodadvance
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http://dx.doi.org/10.1182/bloodadvances.2017005694DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728330PMC
September 2017

GRP78 haploinsufficiency suppresses acinar-to-ductal metaplasia, signaling, and mutant -driven pancreatic tumorigenesis in mice.

Proc Natl Acad Sci U S A 2017 05 1;114(20):E4020-E4029. Epub 2017 May 1.

Department of Biochemistry and Molecular Biology, University of Southern California Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089-9176;

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http://dx.doi.org/10.1073/pnas.1616060114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5441757PMC
May 2017

PET Imaging of Dll4 Expression in Glioblastoma and Colorectal Cancer Xenografts Using (64)Cu-Labeled Monoclonal Antibody 61B.

Mol Pharm 2015 Oct 28;12(10):3527-34. Epub 2015 Aug 28.

Biomedical Research Imaging Center, Department of Radiology, University of North Carolina , Chapel Hill, North Carolina 27514, United States.

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http://dx.doi.org/10.1021/acs.molpharmaceut.5b00105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5444668PMC
October 2015

Small-Animal PET Imaging of Pancreatic Cancer Xenografts Using a 64Cu-Labeled Monoclonal Antibody, MAb159.

J Nucl Med 2015 Jun 23;56(6):908-13. Epub 2015 Apr 23.

Department of Radiology and Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina Molecular Imaging Center, Department of Radiology, University of Southern California, Los Angeles, California

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http://dx.doi.org/10.2967/jnumed.115.155812DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448786PMC
June 2015

Novel EPHB4 Receptor Tyrosine Kinase Mutations and Kinomic Pathway Analysis in Lung Cancer.

Sci Rep 2015 Jun 15;5:10641. Epub 2015 Jun 15.

Department of Medicine, Section of Hematology/Oncology, University of Chicago, Chicago, Illinois, United States of America.

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http://dx.doi.org/10.1038/srep10641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4466581PMC
June 2015

Design, synthesis, and validation of Axl-targeted monoclonal antibody probe for microPET imaging in human lung cancer xenograft.

Mol Pharm 2014 Nov 9;11(11):3974-9. Epub 2014 Jul 9.

Molecular Imaging Center, Department of Radiology, University of Southern California , Los Angeles, California 90089, United States.

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http://dx.doi.org/10.1021/mp500307tDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224514PMC
November 2014

AXL mediates resistance to cetuximab therapy.

Cancer Res 2014 Sep 18;74(18):5152-64. Epub 2014 Aug 18.

Department of Human Oncology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-0294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167493PMC
September 2014

Axl-targeted cancer imaging with humanized antibody h173.

Mol Imaging Biol 2014 Aug;16(4):511-8

Molecular Imaging Center, Department of Radiology, University of Southern California, 2250 Alcazar St. CSC103, Los Angeles, CA, 90033, USA.

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http://link.springer.com/10.1007/s11307-013-0714-z
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http://dx.doi.org/10.1007/s11307-013-0714-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4183751PMC
August 2014

Monoclonal antibody against cell surface GRP78 as a novel agent in suppressing PI3K/AKT signaling, tumor growth, and metastasis.

Clin Cancer Res 2013 Dec 18;19(24):6802-11. Epub 2013 Sep 18.

Authors' Affiliations: Departments of Pathology, Biochemistry and Molecular Biology, and Radiology; School of Pharmacy, University of Southern California Keck School of Medicine, USC Norris Comprehensive Cancer Center; and VasGene Therapeutics Inc., Los Angeles, California.

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http://dx.doi.org/10.1158/1078-0432.CCR-13-1106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151476PMC
December 2013

EphB4-targeted imaging with antibody h131, h131-F(ab')2 and h131-Fab.

Mol Pharm 2013 Dec 7;10(12):4527-33. Epub 2013 Nov 7.

Department of Radiology, The Third Affiliated Hospital of Sun Yat-sen University , Guangzhou, 510630, China.

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http://dx.doi.org/10.1021/mp400354yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888823PMC
December 2013

PET imaging of colorectal and breast cancer by targeting EphB4 receptor with 64Cu-labeled hAb47 and hAb131 antibodies.

J Nucl Med 2013 Jul 10;54(7):1094-100. Epub 2013 May 10.

Molecular Imaging Center, Department of Radiology, University of Southern California, Los Angeles, California 90033, USA.

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http://dx.doi.org/10.2967/jnumed.112.116822DOI Listing
July 2013

EphB4 as a therapeutic target in mesothelioma.

BMC Cancer 2013 May 30;13:269. Epub 2013 May 30.

School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1186/1471-2407-13-269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671960PMC
May 2013

Targeting the EphB4 receptor for cancer diagnosis and therapy monitoring.

Mol Pharm 2013 Jan 18;10(1):329-36. Epub 2012 Dec 18.

Department of Radiology, Molecular Imaging Center, University of Southern California, Los Angeles, California 90033, United States.

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http://dx.doi.org/10.1021/mp300461bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3540204PMC
January 2013

Inhibition of Notch signaling by Dll4-Fc promotes reperfusion of acutely ischemic tissues.

Biochem Biophys Res Commun 2012 Feb 9;418(1):173-9. Epub 2012 Jan 9.

Department of Pathology, University of Southern California, Los Angeles, USA.

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http://dx.doi.org/10.1016/j.bbrc.2012.01.002DOI Listing
February 2012

Ocular safety profile and intraocular pharmacokinetics of an antagonist of EphB4/EphrinB2 signalling.

Br J Ophthalmol 2010 Dec 7;94(12):1668-73. Epub 2010 Oct 7.

Jacobs Retina Center at Shiley Eye Center, University of California, San Diego, La Jolla, CA 92037-0946, USA.

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http://dx.doi.org/10.1136/bjo.2010.182881DOI Listing
December 2010

Induction, regulation, and biologic function of Axl receptor tyrosine kinase in Kaposi sarcoma.

Blood 2010 Jul 4;116(2):297-305. Epub 2010 May 4.

Department of Medicine, University of Southern California, Norris Hospital, 1441 Eastlake Ave., Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1182/blood-2009-12-257154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2910613PMC
July 2010

Soluble EphB4 inhibition of PDGF-induced RPE migration in vitro.

Invest Ophthalmol Vis Sci 2010 Jan 20;51(1):543-52. Epub 2009 Aug 20.

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA.

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http://dx.doi.org/10.1167/iovs.09-3475DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828363PMC
January 2010

Preferential induction of EphB4 over EphB2 and its implication in colorectal cancer progression.

Cancer Res 2009 May 14;69(9):3736-45. Epub 2009 Apr 14.

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3232DOI Listing
May 2009

Loss of Notch signalling induced by Dll4 causes arterial calibre reduction by increasing endothelial cell response to angiogenic stimuli.

BMC Dev Biol 2008 Dec 16;8:117. Epub 2008 Dec 16.

Centro Interdisciplinar de Investigação em Sanidade Animal, Faculdade de Medicina Veterinária, Technical University of Lisbon, Lisboa, Portugal.

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http://bmcdevbiol.biomedcentral.com/articles/10.1186/1471-21
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http://dx.doi.org/10.1186/1471-213X-8-117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637862PMC
December 2008

Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryos.

Blood 2008 Sep 17;112(5):1720-9. Epub 2008 Jun 17.

Centro de Informatica do Instituto Superior de Agronomia (CIISA), Lisbon Technical University, Lisbon, Portugal.

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http://dx.doi.org/10.1182/blood-2007-09-112748DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2518882PMC
September 2008

The significance of EphB4 and EphrinB2 expression and survival in head and neck squamous cell carcinoma.

Arch Otolaryngol Head Neck Surg 2008 Sep;134(9):985-91

Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine, University of Southern California, Hoffman Medical Research 903, 2011 Zonal Ave, Los Angeles, CA 90033, USA.

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http://archotol.jamanetwork.com/article.aspx?doi=10.1001/arc
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http://dx.doi.org/10.1001/archotol.134.9.985DOI Listing
September 2008

Interleukin-2, interleukin-12, and interferon-gamma levels and risk of young adult Hodgkin lymphoma.

Blood 2008 Apr 12;111(7):3377-82. Epub 2007 Dec 12.

Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles 90089-9175, USA.

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http://dx.doi.org/10.1182/blood-2007-08-106872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2275007PMC
April 2008

The origin of Kaposi sarcoma.

Authors:
Parkash S Gill

J Natl Cancer Inst 2007 Jul 10;99(14):1063. Epub 2007 Jul 10.

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http://dx.doi.org/10.1093/jnci/djm063DOI Listing
July 2007

Framework shuffling of antibodies to reduce immunogenicity and manipulate functional and biophysical properties.

Mol Immunol 2007 Apr 22;44(11):3049-60. Epub 2007 Jan 22.

Department of Antibody Discovery and Protein Engineering, MedImmune, Inc., One Medimmune Way, Gaithersburg, MD 20878, USA.

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http://dx.doi.org/10.1016/j.molimm.2006.12.019DOI Listing
April 2007

The association between elevated EphB4 expression, smoking status, and advanced-stage disease in patients with head and neck squamous cell carcinoma.

Arch Otolaryngol Head Neck Surg 2006 Oct;132(10):1053-9

Department of Otolaryngology, Keck School of Medicine, University of Southern California, Los Angeles 90033, USA.

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http://dx.doi.org/10.1001/archotol.132.10.1053DOI Listing
October 2006

EphB4 provides survival advantage to squamous cell carcinoma of the head and neck.

Int J Cancer 2006 Sep;119(6):1236-48

Department of Pathology, University of Southern California, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1002/ijc.21926DOI Listing
September 2006

Receptor tyrosine kinase EphB4 is a survival factor in breast cancer.

Am J Pathol 2006 Jul;169(1):279-93

Department of Pathology, Keck School of Medicine of the University of Southern California, 1441 Eastlake Avenue, NOR 6330, Los Angeles, CA 90033, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698769PMC
http://dx.doi.org/10.2353/ajpath.2006.050889DOI Listing
July 2006

Expression and significance of vascular endothelial growth factor receptor 2 in bladder cancer.

J Urol 2006 Apr;175(4):1245-52

Department of Medicine, Keck School of Medicine of the University of Southern California, California, USA.

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http://dx.doi.org/10.1016/S0022-5347(05)00736-6DOI Listing
April 2006

Soluble EphB4 regulates choroidal endothelial cell function and inhibits laser-induced choroidal neovascularization.

Invest Ophthalmol Vis Sci 2005 Dec;46(12):4772-9

Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, USA.

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http://dx.doi.org/10.1167/iovs.05-0502DOI Listing
December 2005

Up-regulation of EphB4 in mesothelioma and its biological significance.

Clin Cancer Res 2005 Jun;11(12):4305-15

Department of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90033-9172, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-2109DOI Listing
June 2005

Ephrin B2 expression in Kaposi sarcoma is induced by human herpesvirus type 8: phenotype switch from venous to arterial endothelium.

Blood 2005 Feb 7;105(3):1310-8. Epub 2004 Oct 7.

Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2004-03-09
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http://dx.doi.org/10.1182/blood-2004-03-0933DOI Listing
February 2005

VEGF antisense therapy inhibits tumor growth and improves survival in experimental pancreatic cancer.

Surgery 2005 Feb;137(2):192-9

Department of Surgery, School of Medicine, University of California-Los Angeles, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/j.surg.2004.07.015DOI Listing
February 2005

Th1 and Th2 cytokines and IgE levels in identical twins with varying levels of cigarette consumption.

J Clin Immunol 2004 Nov;24(6):617-22

Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90089-9175, USA.

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http://dx.doi.org/10.1007/s10875-004-6247-0DOI Listing
November 2004

VEGF and myeloid leukemias.

Leuk Res 2004 Jul;28(7):675-7

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http://dx.doi.org/10.1016/j.leukres.2003.12.013DOI Listing
July 2004

Expression of EphB4 in head and neck squamous cell carcinoma.

Ear Nose Throat J 2003 Nov;82(11):866, 869-70, 887

Department of Otolaryngology-Head and Neck Surgery, Keck School of Medicine, University of Southern California, Los Angeles, USA.

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November 2003

Natural killer cell cytolytic activity is necessary for in vivo antitumor activity of the dipeptide L-glutamyl-L-tryptophan.

Int J Cancer 2003 Sep;106(4):528-33

University of Southern California Keck School of Medicine, USC/Norris Comprehensive Cancer Center, Los Angeles, CA 90033, USA.

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http://dx.doi.org/10.1002/ijc.11253DOI Listing
September 2003

Malignant mesothelioma growth inhibition by agents that target the VEGF and VEGF-C autocrine loops.

Int J Cancer 2003 May;104(5):603-10

Department of Pathology, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1002/ijc.10996DOI Listing
May 2003

A multicenter phase II study of the intravenous administration of liposomal tretinoin in patients with acquired immunodeficiency syndrome-associated Kaposi's sarcoma.

Cancer 2002 Dec;95(12):2555-61

Department of Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, New York 14263, USA.

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http://dx.doi.org/10.1002/cncr.11009DOI Listing
December 2002

Multicenter trial of low-dose paclitaxel in patients with advanced AIDS-related Kaposi sarcoma.

Cancer 2002 Jul;95(1):147-54

Division of Hematology, Department of Medicine, Kenneth Norris Cancer Hospital and Research Institute, University of Southern California School of Medicine, Los Angeles, California, USA.

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http://dx.doi.org/10.1002/cncr.10634DOI Listing
July 2002

Multidrug resistance (MDR-1) expression in AIDS-related lymphomas.

Leuk Res 2002 Feb;26(2):121-7

Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.

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http://dx.doi.org/10.1016/s0145-2126(01)00113-8DOI Listing
February 2002