Parisa Moazzam

Miss Parisa Moazzam

PhD

University of New South Wales (UNSW), Chemistry School

PhD student

Sydney , NSW | Australia

Parisa Moazzam

Miss Parisa Moazzam

PhD
Introduction

Primary Affiliation: University of New South Wales (UNSW), Chemistry School - Sydney , NSW , Australia

Research Interests:

Metrics

2

Publications

1191

Profile Views

-

Reads

Education
Mar 2016
Master of Nano Science and Technology
MSc
Experience
Apr 2017
The Superhydrophobic Modification on The Aluminum Surface to Study Biological interaction: Protein Adsorption and Bacterial Attachment
Researcher
Top co-authors

Publications

2Publications

-Reads

Nanostructured mesoporous carbon polyethersulfone composite ultrafiltration membrane with significantly low protein adsorption and bacterial adhesion

http://dx.doi.org/10.1016/j.carbon.2016.10.055

Carbon

A novel polyethersulfone (PES) ultrafiltration membrane containing 0.05–2.00 wt% of synthesized mesoporous carbon nanoparticles (MCNs) was prepared via the phase inversion technique. The structures and properties of MCNs were characterized using a variety of analytic techniques. The MCNs showed the surface area of 1396.8 m2/g and the highest pore size of around 1 nm. The effect of incorporation of MCNs on the composite membrane morphology and performance was investigated through pure water flux, protein adsorption, and bacterial adhesion resistance tests. The membrane's anti-fouling performances were determined under constant-pressure operation at 100 kPa in a dead-end module. The as-prepared nanocomposite membranes were also studied in terms of morphology, structure and surface chemistry. Generally, the incorporation of MCNs into the polymeric membrane improved the pure water flux. The composite membrane containing 0.20 wt% MCNs exhibited the highest antifouling, protein adsorption resistance, and bacterial attachment inhibition property. The incorporation of the MCNs into the membranes introduces a different strategy of inhibiting biomolecule adsorption and bacterial attachment to the membrane surface, instead of killing the bacteria which may lead to more severe membrane fouling by the intracellular substances.

View Article
October 2016
20 Reads

Investigating the BSA protein adsorption and bacterial adhesion of Al-alloy surfaces after creating a hierarchical (micro/nano) superhydrophobic structure.

J Biomed Mater Res A. 2016 Sep;104(9):2220-33. doi: 10.1002/jbm.a.35751. Epub 2016 May 6

J Biomed Mater Res A.

Bacterial adhesion and subsequent biofilm formation on metals such as aluminum (Al) alloys lead to serious issues in biomedical and industrial fields from both an economical and health perspective. Here, we showed that a careful manipulation of Al surface characteristics via a facile two-steps superhydrophobic modification can provide not only biocompatibility and an ability to control protein adsorption and bacterial adhesion, but also address the issue of apparent long-term toxicity of Al-alloys. To find out the roles of surface characteristics, surface modification and protein adsorption on microbial adhesion and biofilm formation, the surfaces were systematically characterized by SEM, EDX, XPS, AFM, FTIR, water contact angle (WCA) goniometry, surface free energy (SFE) measurement, MTT, Bradford, Lowry and microtiter plate assays and also flow-cytometry and potentiostat analyses. Results showed that WCA and SFE changed from 70° to 163° and 36.3 to 0.13 mN m(-1) , respectively. The stable and durable modification led to a substantial reduction in static/dynamic BSA adsorption. The effect of such a treatment on the biofilm formation was analyzed by using three different bacteria of Pseudomonas aeruginosa, Staphylococcus epidermidis, and Staphylococcus aureus. The microtiter plate assay and flow cytometry analysis showed that the modification not only could substantially reduce the bacterial adhesion but this biofouling resistance is independent of bacterium type. An excellent cell viability after exposure of HeLa cells to waters incubated with the modified samples was observed. Finally, the corrosion rate reduced sharply from 856.6 to 0.119 MPY after superhydrophobic modifications, which is an excellent stable corrosion inhibition property. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 2220-2233, 2016.

View Article
September 2016
27 Reads