Paolo Verderio

Analysis of the mutational status of SIX1/2 and microRNA processing genes in paired primary and relapsed Wilms tumors and association with relapse.

Cancer Gene Ther 2020 Dec 6. Epub 2020 Dec 6.

Molecular Bases of Genetic Risk and Genetic Testing Unit, Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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December 2020

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy.

Int J Mol Sci 2020 Feb 18;21(4). Epub 2020 Feb 18.

Biomarker Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, 20100 Milan, Italy.

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February 2020

κ and λ urine free light chains: a new method for quantification.

Authors:

Marta Giussani Chiara Maura Ciniselli Alessandra Macciotta Rossella Panella Paolo Verderio Chiara Bonini Daniele Morelli

Tumori 2020 Dec 20;106(6):457-463. Epub 2020 Jan 20.

Laboratory Medicine Unit, Diagnostic Pathology and Laboratory Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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December 2020

Short-term and long-term outcomes after preventive surgery in adolescent patients with familial adenomatous polyposis.

Authors:

Marco Vitellaro Guglielmo Piozzi Stefano Signoroni Maria Teresa Ricci Chiara Maura Ciniselli Anna Cardani Irene Vecchi Andrea Mancini Andrea Magarotto Paolo Verderio Maura Massimino Andrea Ferrari Davide Biasoni

Pediatr Blood Cancer 2020 03 5;67(3):e28110. Epub 2019 Dec 5.

Pediatric Surgery Unit, Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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March 2020

Plasma miRNA-based signatures in CRC screening programs.

Int J Cancer 2020 02 5;146(4):1164-1173. Epub 2019 Aug 5.

Tumor Genomics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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February 2020

The 41-gene classifier TRAR predicts response of HER2 positive breast cancer patients in the NeoALTTO study.

Eur J Cancer 2019 09 5;118:1-9. Epub 2019 Jul 5.

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy. Electronic address:

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September 2019

High-dose-rate brachytherapy for high-grade vaginal intraepithelial neoplasia: a dosimetric analysis.

Authors:

Amelia Barcellini Mara Lecchi Chiara Tenconi Alessandra Macciotta Emanuele Pignoli Brigida Pappalardi Ester Mazzarella Mauro Carrara Tommaso Giandini Carlo Fallai Paolo Verderio Annamaria Cerrotta

J Contemp Brachytherapy 2019 Apr 29;11(2):146-151. Epub 2019 Apr 29.

Radiotherapy 2 Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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April 2019

Monitoring Vitamin B in Women Treated with Metformin for Primary Prevention of Breast Cancer and Age-Related Chronic Diseases.

Authors:

Antonio Mastroianni Chiara Maura Ciniselli Rossella Panella Alessandra Macciotta Adalberto Cavalleri Elisabetta Venturelli Francesca Taverna Arabella Mazzocchi Eleonora Bruno Paola Muti Franco Berrino Paolo Verderio Daniele Morelli Patrizia Pasanisi

Nutrients 2019 May 7;11(5). Epub 2019 May 7.

Epidemiology and Prevention Unit-Department of Research, Fondazione IRCSS Istituto Nazionale dei Tumori di Milano, 20133 Milano, Italy.

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May 2019

Methodological and statistical issues in developing an External Quality Assessment scheme in laboratory medicine: Focus on biomarker research.

Authors:

Paolo Verderio Sara Pizzamiglio Chiara Maura Ciniselli

N Biotechnol 2019 Sep 3;52:54-59. Epub 2019 May 3.

Bioinformatics and Biostatistics Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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September 2019

A Pilot Low-Inflammatory Dietary Intervention to Reduce Inflammation and Improve Quality of Life in Patients With Familial Adenomatous Polyposis: Protocol Description and Preliminary Results.

Authors:

Patrizia Pasanisi Manuela Gariboldi Paolo Verderio Stefano Signoroni Andrea Mancini Licia Rivoltini Massimo Milione Enzo Masci Chiara Maura Ciniselli Eleonora Bruno Alessandra Macciotta Antonino Belfiore Maria Teresa Ricci Giuliana Gargano Daniele Morelli Giovanni Apolone Marco Vitellaro

Integr Cancer Ther 2019 Jan-Dec;18:1534735419846400

4 Unit of Hereditary Digestive Tract Tumors, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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December 2019

Plasma miRNA Levels for Predicting Therapeutic Response to Neoadjuvant Treatment in HER2-positive Breast Cancer: Results from the NeoALTTO Trial.

Authors:

Serena Di Cosimo Valentina Appierto Sara Pizzamiglio Paola Tiberio Marilena V Iorio Florentine Hilbers Evandro de Azambuja Lorena de la Peña Miguel Izquierdo Jens Huober José Baselga Martine Piccart Filippo G de Braud Giovanni Apolone Paolo Verderio Maria Grazia Daidone

Clin Cancer Res 2019 07 27;25(13):3887-3895. Epub 2019 Feb 27.

Biomarkers Unit, Department of Applied Research and Technological Development, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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July 2019

Combination of Baseline LDH, Performance Status and Age as Integrated Algorithm to Identify Solid Tumor Patients with Higher Probability of Response to Anti PD-1 and PD-L1 Monoclonal Antibodies.

Authors:

Maria Silvia Cona Mara Lecchi Sara Cresta Silvia Damian Michele Del Vecchio Andrea Necchi Marta Maria Poggi Daniele Raggi Giovanni Randon Raffaele Ratta Diego Signorelli Claudio Vernieri Filippo de Braud Paolo Verderio Massimo Di Nicola

Cancers (Basel) 2019 Feb 14;11(2). Epub 2019 Feb 14.

Medical Oncology Unit, Fondazione IRCCS, Istituto Nazionale dei Tumori di Milano, Via Giacomo Venezian 1, 20133 Milan, Italy.

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February 2019

The impact of chemotherapy on survival of patients with extremity and trunk wall soft tissue sarcoma: revisiting the results of the EORTC-STBSG 62931 randomised trial.

Authors:

Sandro Pasquali Sara Pizzamiglio Nathan Touati Saskia Litiere Sandrine Marreaud Bernd Kasper Hans Gelderblom Silvia Stacchiotti Ian Judson Angelo P Dei Tos Paolo Verderio Paolo G Casali Penella J Woll Alessandro Gronchi

Eur J Cancer 2019 03 25;109:51-60. Epub 2019 Jan 25.

Sarcoma Service, Department of Surgery, Fondazione IRCCS Istituto Nazionale Dei Tumori, Milan, Italy. Electronic address:

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March 2019

Constitutive Promoter Hypermethylation Can Be a Predisposing Event in Isolated Early-Onset Breast Cancer.

Authors:

Jacopo Azzollini Chiara Pesenti Sara Pizzamiglio Laura Fontana Carmela Guarino Bernard Peissel Maddalena Plebani Silvia Tabano Silvia Maria Sirchia Patrizia Colapietro Roberta Villa Biagio Paolini Paolo Verderio Monica Miozzo Siranoush Manoukian

Cancers (Basel) 2019 Jan 9;11(1). Epub 2019 Jan 9.

Unit of Medical Genetics, Department of Medical Oncology and Hematology, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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January 2019

Different pixel pitch and maximum luminance of medical grade displays may result in different evaluations of digital radiography images.

Authors:

Alberto Laffranchi Calogero Cicero Manuela Lualdi Chiara M Ciniselli Giuseppina Calareso Stefano Canestrini Francesca G Greco Enrico Alberioli Claudia Cavatorta Alessandro Guarise Emanuele Pignoli Maddalena Plebani Davide Scaramuzza Claudio Siciliano Paolo Verderio Alfonso Marchianò

Radiol Med 2018 Aug 18;123(8):586-592. Epub 2018 Apr 18.

Department of Radiology, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133, Milan, Italy.

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August 2018

Impact of the strategy adopted for drug loading in nonporous silica nanoparticles on the drug release and cytotoxic activity.

Authors:

Benedetta Riva Michela Bellini Eleonora Corvi Paolo Verderio Ewa Rozek Barbara Colzani Svetlana Avvakumova Annalisa Radeghieri Maria Antonietta Rizzuto Carlo Morasso Miriam Colombo Davide Prosperi

J Colloid Interface Sci 2018 Jun 14;519:18-26. Epub 2018 Feb 14.

Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy; Nanomedicine Laboratory, ICS Maugeri S. p. A. SB, via S. Maugeri 10, 27100 Pavia, Italy. Electronic address:

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June 2018

High-risk soft tissue sarcomas treated with perioperative chemotherapy: Improving prognostic classification in a randomised clinical trial.

Eur J Cancer 2018 04 21;93:28-36. Epub 2018 Feb 21.

Department of Surgery, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. Electronic address:

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April 2018

In situ hybridization detection methods for HPV16 E6/E7 mRNA in identifying transcriptionally active HPV infection of oropharyngeal carcinoma: an updating.

Authors:

Chiara C Volpi Chiara M Ciniselli Ambra V Gualeni Maddalena Plebani Salvatore Alfieri Paolo Verderio Laura Locati Federica Perrone Pasquale Quattrone Antonino Carbone Silvana Pilotti Annunziata Gloghini

Hum Pathol 2018 04 6;74:32-42. Epub 2017 Oct 6.

Department of Pathology and Laboratory Medicine, Fondazione IRCCS, Istituto Nazionale dei Tumori, 20133 Milan, Italy. Electronic address:

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April 2018

β-Catenin in desmoid-type fibromatosis: deep insights into the role of T41A and S45F mutations on protein structure and gene expression.

Authors:

Chiara Colombo Antonino Belfiore Nicholas Paielli Loris De Cecco Silvana Canevari Erik Laurini Maurizio Fermeglia Sabrina Pricl Paolo Verderio Stefano Bottelli Marco Fiore Silvia Stacchiotti Elena Palassini Alessandro Gronchi Silvana Pilotti Federica Perrone

Mol Oncol 2017 11 29;11(11):1495-1507. Epub 2017 Sep 29.

Laboratory of Experimental Molecular Pathology, Department of Pathology, Fondazione IRCCS Istituto Nazionale Tumori, Milan, Italy.

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November 2017

Proteomic analysis of cerebrospinal fluid from children with central nervous system tumors identifies candidate proteins relating to tumor metastatic spread.

Authors:

Filippo Spreafico Italia Bongarzone Sara Pizzamiglio Ruben Magni Elena Taverna Maida De Bortoli Chiara M Ciniselli Elena Barzanò Veronica Biassoni Alessandra Luchini Lance A Liotta Weidong Zhou Michele Signore Paolo Verderio Maura Massimino

Oncotarget 2017 Jul;8(28):46177-46190

Pediatric Oncology Unit, Department of Hematology and Pediatric Hematology-Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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July 2017

Development of Tc-radiolabeled nanosilica for targeted detection of HER2-positive breast cancer.

Authors:

Paolo Rainone Benedetta Riva Sara Belloli Francesco Sudati Marilena Ripamonti Paolo Verderio Miriam Colombo Barbara Colzani Maria Carla Gilardi Rosa Maria Moresco Davide Prosperi

Int J Nanomedicine 2017 2;12:3447-3461. Epub 2017 May 2.

NanoBioLab, Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, Milano.

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August 2017

Detection of Circulating Tumour Cells in Urothelial Cancers and Clinical Correlations: Comparison of Two Methods.

Authors:

Emanuela Fina Andrea Necchi Stefano Bottelli Carolina Reduzzi Sara Pizzamiglio Chiara Iacona Maria Grazia Daidone Paolo Verderio Vera Cappelletti

Dis Markers 2017 22;2017:3414910. Epub 2017 Feb 22.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

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March 2017

Expression of Iron-Related Proteins Differentiate Non-Cancerous and Cancerous Breast Tumors.

Authors:

Sara Pizzamiglio Maida De Bortoli Elena Taverna Michele Signore Silvia Veneroni William Chi-Shing Cho Rosaria Orlandi Paolo Verderio Italia Bongarzone

Int J Mol Sci 2017 Feb 14;18(2). Epub 2017 Feb 14.

Proteomics Laboratory, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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February 2017

How Does the Display Luminance Level Affect Detectability of Breast Microcalcifications and Spiculated Lesions in Digital Breast Tomosynthesis (DBT) Images?

Authors:

Claudio Ferranti Alessandra Primolevo Francesco Cartia Claudia Cavatorta Chiara Maura Ciniselli Manuela Lualdi Silvia Meroni Emanuele Pignoli Maddalena Plebani Claudio Siciliano Paolo Verderio Gianfranco Scaperrotta

Acad Radiol 2017 07 8;24(7):795-801. Epub 2017 Feb 8.

Breast Imaging Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian 1, 20133 Milano, Italy.

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July 2017

A methodological procedure for evaluating the impact of hemolysis on circulating microRNAs.

Authors:

Sara Pizzamiglio Susanna Zanutto Chiara M Ciniselli Antonino Belfiore Stefano Bottelli Manuela Gariboldi Paolo Verderio

Oncol Lett 2017 Jan 30;13(1):315-320. Epub 2016 Nov 30.

Unit of Medical Statistics, Biometry and Bioinformatics, Scientific Institutes for Research and Treatment Foundation 'National Cancer Institute', I-20133 Milan, Italy.

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January 2017

The focus on sample quality: Influence of colon tissue collection on reliability of qPCR data.

Authors:

Vlasta Korenkova Jana Slyskova Vendula Novosadova Sara Pizzamiglio Lucie Langerova Jens Bjorkman Ondrej Vycital Vaclav Liska Miroslav Levy Karel Veskrna Pavel Vodicka Ludmila Vodickova Mikael Kubista Paolo Verderio

Sci Rep 2016 07 7;6:29023. Epub 2016 Jul 7.

Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milan, Italy.

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July 2016

Developing miRNA signatures: a multivariate prospective.

Authors:

Paolo Verderio Stefano Bottelli Sara Pizzamiglio Chiara Maura Ciniselli

Br J Cancer 2016 06;115(1):1-4

Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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June 2016

In a cohort of breast cancer screened patients the proportion of HER2 positive cases is lower than that earlier reported and pathological characteristics differ between HER2 3+ and HER2 2+/Her2 amplified cases.

Authors:

Silvia Giuliani Chiara Maura Ciniselli Elena Leonardi Enzo Polla Nicola Decarli Claudio Luchini Chiara Cantaloni Fabio Gasperetti Daniela Cazzolli Gabriella Berlanda Daniela Bernardi Marco Pellegrini Renza Triolo Antonella Ferro Paolo Verderio Mattia Barbareschi

Virchows Arch 2016 Jul 21;469(1):45-50. Epub 2016 Apr 21.

Unit of Surgical Pathology, Santa Chiara Hospital, Largo Medaglie Oro 9, 38122, Trento, Italy.

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July 2016

Data and performances evaluation of the SPIDIA-DNA Pan-European External Quality Assessment: 2nd SPIDIA-DNA laboratory report.

Authors:

Francesca Malentacchi Sara Pizzamiglio Hady Ibrahim-Gawel Mario Pazzagli Paolo Verderio Chiara Maura Ciniselli Ralf Wyrich Stefania Gelmini

Data Brief 2016 Mar 6;6:980-4. Epub 2016 Feb 6.

Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Italy.

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March 2016

Effects of Transport and Storage Conditions on Gene Expression in Blood Samples.

Authors:

Francesca Malentacchi Sara Pizzamiglio Ralf Wyrich Paolo Verderio Chiara Ciniselli Mario Pazzagli Stefania Gelmini

Biopreserv Biobank 2016 Apr 17;14(2):122-8. Epub 2016 Feb 17.

1 Department of Biomedical, Experimental and Clinical Sciences, University of Florence , Italy .

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April 2016

Second SPIDIA-DNA External Quality Assessment (EQA): Influence of pre-analytical phase of blood samples on genomic DNA quality.

Authors:

Francesca Malentacchi Sara Pizzamiglio Hady Ibrahim-Gawel Mario Pazzagli Paolo Verderio Chiara Maura Ciniselli Ralf Wyrich Stefania Gelmini

Clin Chim Acta 2016 Feb 23;454:10-4. Epub 2015 Dec 23.

Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Italy.

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February 2016

Tuning of nanoparticle biological functionality through controlled surface chemistry and characterisation at the bioconjugated nanoparticle surface.

Authors:

Delyan R Hristov Louise Rocks Philip M Kelly Steffi S Thomas Andrzej S Pitek Paolo Verderio Eugene Mahon Kenneth A Dawson

Sci Rep 2015 Dec 1;5:17040. Epub 2015 Dec 1.

Centre for BioNano Interactions, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.

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December 2015

Androgen receptor CAG repeat length and estrogen receptor status in postmenopausal breast cancer prognosis.

Authors:

Patrizia Cogliati Chiara Maura Ciniselli Roberto Agresti Biagio Paolini Chiara Bonini Paolo Radice Vittorio Krogh Paolo Verderio Elisabetta Venturelli

Int J Biol Markers 2015 Nov 11;30(4):e418-24. Epub 2015 Nov 11.

Department of Preventive & Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan - Italy.

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November 2015

Reproducibility between messenger RNA real-time polymerase chain reaction and messenger RNA in situ hybridization in oropharyngeal squamous cell carcinoma patients.

Authors:

Chiara Maura Ciniselli Chiara C Volpi Barbara Cortelazzi Ambra V Gualeni Stefano Bottelli Federica Perrone Silvana Pilotti Annunziata Gloghini Paolo Verderio

Hum Pathol 2016 Jan 3;47(1):157-8. Epub 2015 Oct 3.

Unit of Medical Statistics, Biometry and Bioinformatics, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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January 2016

Plasma hepcidin in early-stage breast cancer patients: no relationship with interleukin-6, erythropoietin and erythroferrone.

Authors:

Chiara Maura Ciniselli Maida De Bortoli Elena Taverna Luca Varinelli Sara Pizzamiglio Silvia Veneroni Chiara Bonini Rosaria Orlandi Paolo Verderio Italia Bongarzone

Expert Rev Proteomics 2015 23;12(6):695-701. Epub 2015 Oct 23.

b Laboratory of Proteomics , Fondazione IRCCS Istituto Nazionale dei Tumori , Milan , Italy.

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January 2017

Feasibility of Preoperative Chemotherapy With or Without Radiation Therapy in Localized Soft Tissue Sarcomas of Limbs and Superficial Trunk in the Italian Sarcoma Group/Grupo Español de Investigación en Sarcomas Randomized Clinical Trial: Three Versus Five Cycles of Full-Dose Epirubicin Plus Ifosfamide.

Authors:

Elena Palassini Stefano Ferrari Paolo Verderio Antonino De Paoli Javier Martin Broto Vittorio Quagliuolo Alessandro Comandone Claudia Sangalli Emanuela Palmerini Antonio Lopez-Pousa Rita De Sanctis Stefano Bottelli Michela Libertini Piero Picci Paolo G Casali Alessandro Gronchi

J Clin Oncol 2015 Nov 8;33(31):3628-34. Epub 2015 Sep 8.

Elena Palassini, Paolo Verderio, Claudia Sangalli, Stefano Bottelli, Michela Libertini, Paolo G. Casali, and Alessandro Gronchi, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori; Vittorio Quagliuolo and Rita De Sanctis, Istituto Clinico Humanitas, Milan; Stefano Ferrari, Emanuela Palmerini, and Piero Picci, Istituto Ortopedico Rizzoli, Bologna; Antonino De Paoli, Centro di Riferimento Oncologico, Aviano; Alessandro Comandone, Presidio Sanitario Gradenigo, Torino, Italy; Javier Martin Broto, Hospital Universitario Virgen del Rocío, Sevilla; and Antonio Lopez-Pousa, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.

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November 2015

FANCM c.5791C>T nonsense mutation (rs144567652) induces exon skipping, affects DNA repair activity and is a familial breast cancer risk factor.

Authors:

Paolo Peterlongo Irene Catucci Mara Colombo Laura Caleca Eliseos Mucaki Massimo Bogliolo Maria Marin Francesca Damiola Loris Bernard Valeria Pensotti Sara Volorio Valentina Dall'Olio Alfons Meindl Claus Bartram Christian Sutter Harald Surowy Valérie Sornin Marie-Gabrielle Dondon Séverine Eon-Marchais Dominique Stoppa-Lyonnet Nadine Andrieu Olga M Sinilnikova Gillian Mitchell Paul A James Ella Thompson Marina Marchetti Cristina Verzeroli Carmen Tartari Gabriele Lorenzo Capone Anna Laura Putignano Maurizio Genuardi Veronica Medici Isabella Marchi Massimo Federico Silvia Tognazzo Laura Matricardi Simona Agata Riccardo Dolcetti Lara Della Puppa Giulia Cini Viviana Gismondi Valeria Viassolo Chiara Perfumo Maria Antonietta Mencarelli Margherita Baldassarri Bernard Peissel Gaia Roversi Valentina Silvestri Piera Rizzolo Francesca Spina Caterina Vivanet Maria Grazia Tibiletti Maria Adelaide Caligo Gaetana Gambino Stefania Tommasi Brunella Pilato Carlo Tondini Chiara Corna Bernardo Bonanni Monica Barile Ana Osorio Javier Benitez Luisa Balestrino Laura Ottini Siranoush Manoukian Marco A Pierotti Alessandra Renieri Liliana Varesco Fergus J Couch Xianshu Wang Peter Devilee Florentine S Hilbers Christi J van Asperen Alessandra Viel Marco Montagna Laura Cortesi Orland Diez Judith Balmaña Jan Hauke Rita K Schmutzler Laura Papi Miguel Angel Pujana Conxi Lázaro Anna Falanga Kenneth Offit Joseph Vijai Ian Campbell Barbara Burwinkel Anders Kvist Hans Ehrencrona Sylvie Mazoyer Sara Pizzamiglio Paolo Verderio Jordi Surralles Peter K Rogan Paolo Radice

Hum Mol Genet 2015 Sep 30;24(18):5345-55. Epub 2015 Jun 30.

IFOM, the FIRC Institute of Molecular Oncology, Milan, Italy, Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine.

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September 2015

Influence of storage conditions and extraction methods on the quantity and quality of circulating cell-free DNA (ccfDNA): the SPIDIA-DNAplas External Quality Assessment experience.

Authors:

Francesca Malentacchi Sara Pizzamiglio Paolo Verderio Mario Pazzagli Claudio Orlando Chiara Maura Ciniselli Kalle Günther Stefania Gelmini

Clin Chem Lab Med 2015 Nov;53(12):1935-42

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November 2015

Combining qualitative and quantitative imaging evaluation for the assessment of genomic DNA integrity: The SPIDIA experience.

Authors:

Chiara Maura Ciniselli Sara Pizzamiglio Francesca Malentacchi Stefania Gelmini Mario Pazzagli Christina C Hartmann Hady Ibrahim-Gawel Paolo Verderio

Anal Biochem 2015 Jun 27;479:60-2. Epub 2015 Mar 27.

Unit of Medical Statistics, Biometry, and Bioinformatics, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy. Electronic address:

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June 2015

Peptide-nanoparticle ligation mediated by cutinase fusion for the development of cancer cell-targeted nanoconjugates.

Authors:

Elisabetta Galbiati Marco Cassani Paolo Verderio Enzo Martegani Miriam Colombo Paolo Tortora Serena Mazzucchelli Davide Prosperi

Bioconjug Chem 2015 Apr 13;26(4):680-9. Epub 2015 Mar 13.

†Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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April 2015

Moving from discovery to validation in circulating microRNA research.

Authors:

Paolo Verderio Stefano Bottelli Chiara M Ciniselli Marco A Pierotti Susanna Zanutto Manuela Gariboldi Sara Pizzamiglio

Int J Biol Markers 2015 May 26;30(2):e258-61. Epub 2015 May 26.

1 Unit of Medical Statistics, Biometry and Bioinformatics, National Cancer Institute, IRCCS Foundation, Milan - Italy.

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May 2015

Receptor tyrosine kinase profiles and human papillomavirus status in oropharyngeal squamous cell carcinoma.

Authors:

Barbara Cortelazzi Paolo Verderio Chiara Maura Ciniselli Sara Pizzamiglio Paolo Bossi Annunziata Gloghini Ambra V Gualeni Chiara C Volpi Laura Locati Marco A Pierotti Lisa Licitra Silvana Pilotti Federica Perrone

J Oral Pathol Med 2015 Oct 14;44(9):734-45. Epub 2014 Dec 14.

Laboratory of Experimental Molecular Pathology, Department of Pathology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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October 2015

SPIDIA-RNA: second external quality assessment for the pre-analytical phase of blood samples used for RNA based analyses.

Authors:

Francesca Malentacchi Mario Pazzagli Lisa Simi Claudio Orlando Ralf Wyrich Kalle Günther Paolo Verderio Sara Pizzamiglio Chiara Maura Ciniselli Hui Zhang Vlasta Korenková Lynne Rainen Tzachi Bar Mikael Kubista Stefania Gelmini

PLoS One 2014 10;9(11):e112293. Epub 2014 Nov 10.

Department of Biomedical Experimental and Clinical Sciences, University of Florence, Florence, Italy.

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July 2015

Biomarkers for monitoring pre-analytical quality variation of mRNA in blood samples.

Authors:

Hui Zhang Vlasta Korenková Robert Sjöback David Švec Jens Björkman Mogens Kruhøffer Paolo Verderio Sara Pizzamiglio Chiara Maura Ciniselli Ralf Wyrich Uwe Oelmueller Mikael Kubista Torbjørn Lindahl Anders Lönneborg Edith Rian

PLoS One 2014 4;9(11):e111644. Epub 2014 Nov 4.

DiaGenic ASA, Oslo, Norway.

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June 2015

Evaluation of colon cancer histomorphology: a comparison between formalin and PAXgene tissue fixation by an international ring trial.

Virchows Arch 2014 Nov 2;465(5):509-19. Epub 2014 Aug 2.

Institute of Pathology, Technische Universität München, Trogerstr. 18, 81675, Munich, Germany.

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November 2014

Histone deacetylase inhibitor-temozolomide co-treatment inhibits melanoma growth through suppression of Chemokine (C-C motif) ligand 2-driven signals.

Authors:

Laura Gatti Alexandra Sevko Michelandrea De Cesare Noemi Arrighetti Giacomo Manenti Emilio Ciusani Paolo Verderio Chiara M Ciniselli Denis Cominetti Nives Carenini Elisabetta Corna Nadia Zaffaroni Monica Rodolfo Licia Rivoltini Viktor Umansky Paola Perego

Oncotarget 2014 Jun;5(12):4516-28

Molecular Pharmacology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. These authors contributed equally to this work.

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June 2014

Antiproliferative effect of ASC-J9 delivered by PLGA nanoparticles against estrogen-dependent breast cancer cells.

Authors:

Paolo Verderio Laura Pandolfi Serena Mazzucchelli Maria Rosaria Marinozzi Renzo Vanna Furio Gramatica Fabio Corsi Miriam Colombo Carlo Morasso Davide Prosperi

Mol Pharm 2014 Aug 18;11(8):2864-75. Epub 2014 Jul 18.

Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca , Piazza della Scienza 2, 20126 Milano, Italy.

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August 2014

NqA: an R-based algorithm for the normalization and analysis of microRNA quantitative real-time polymerase chain reaction data.

Authors:

Paolo Verderio Stefano Bottelli Chiara Maura Ciniselli Marco Alessandro Pierotti Manuela Gariboldi Sara Pizzamiglio

Anal Biochem 2014 Sep 2;461:7-9. Epub 2014 Jun 2.

Unit of Medical Statistics, Biometry, and Bioinformatics, Fondazione IRCCS Istituto Nazionale dei Tumori, 20133 Milan, Italy.

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September 2014

Circulating free DNA in a screening program for early colorectal cancer detection.

Authors:

Federica Perrone Andrea Lampis Claudia Bertan Paolo Verderio Chiara M Ciniselli Sara Pizzamiglio Milo Frattini Martina Nucifora Francesca Molinari Gianfranco Gallino Manuela Gariboldi Emanuele Meroni Ermanno Leo Marco A Pierotti Silvana Pilotti

Tumori 2014 Mar-Apr;100(2):115-21

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July 2014

PALB2 sequencing in Italian familial breast cancer cases reveals a high-risk mutation recurrent in the province of Bergamo.

Genet Med 2014 Sep 20;16(9):688-94. Epub 2014 Feb 20.

Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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September 2014

Association between CASP8 -652 6N del polymorphism (rs3834129) and colorectal cancer risk: results from a multi-centric study.

PLoS One 2014 21;9(1):e85538. Epub 2014 Jan 21.

Fondazione Istituto Italian Foundation for Cancer Research di Oncologia Molecolare, Milan, Italy.

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October 2014

Delivering colloidal nanoparticles to mammalian cells: a nano-bio interface perspective.

Authors:

Paolo Verderio Svetlana Avvakumova Giulia Alessio Michela Bellini Miriam Colombo Elisabetta Galbiati Serena Mazzucchelli Jesus Peñaranda Avila Benedetta Santini Davide Prosperi

Adv Healthc Mater 2014 Jul 20;3(7):957-76. Epub 2014 Jan 20.

Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, piazza della Scienza 2, 20126, Milano, Italy.

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July 2014

PI3KCA mutation status is of limited prognostic relevance in ER-positive breast cancer patients treated with hormone therapy.

Virchows Arch 2014 Jan;464(1):85-93

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January 2014

A normalization strategy for the analysis of plasma microRNA qPCR data in colorectal cancer.

Authors:

Sara Pizzamiglio Stefano Bottelli Chiara Maura Ciniselli Susanna Zanutto Claudia Bertan Manuela Gariboldi Marco Alessandro Pierotti Paolo Verderio

Int J Cancer 2014 Apr 22;134(8):2016-8. Epub 2013 Oct 22.

Unit of Medical Statistics Biometry and Bioinformatics, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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April 2014

External Quality Assessment (EQA) program for the preanalytical and analytical immunohistochemical determination of HER2 in breast cancer: an experience on a regional scale.

J Exp Clin Cancer Res 2013 Aug 21;32:58. Epub 2013 Aug 21.

Pathology Department, Regina Elena National Cancer Institute, Via Elio Chianesi 53, Rome, 00144, Italy.

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August 2013

Orientation-controlled conjugation of haloalkane dehalogenase fused homing peptides to multifunctional nanoparticles for the specific recognition of cancer cells.

Authors:

Serena Mazzucchelli Miriam Colombo Paolo Verderio Ewa Rozek Francesco Andreata Elisabetta Galbiati Paolo Tortora Fabio Corsi Davide Prosperi

Angew Chem Int Ed Engl 2013 Mar 5;52(11):3121-5. Epub 2013 Feb 5.

Dipartimento di Scienze Biomediche e Cliniche Luigi Sacco, Università di Milano, Ospedale L. Sacco, Via G.B. Grassi 74, 20157 Milano, Italy.

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March 2013

Intracellular drug release from curcumin-loaded PLGA nanoparticles induces G2/M block in breast cancer cells.

Authors:

Paolo Verderio Paolo Bonetti Miriam Colombo Laura Pandolfi Davide Prosperi

Biomacromolecules 2013 Mar 15;14(3):672-82. Epub 2013 Feb 15.

Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, piazza della Scienza 2, 20126 Milano, Italy.

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March 2013

Effects of warm ischemic time on gene expression profiling in colorectal cancer tissues and normal mucosa.

Authors:

Valeria Musella Paolo Verderio James Francis Reid Sara Pizzamiglio Manuela Gariboldi Maurizio Callari Massimo Milione Milione Massimo Loris De Cecco Silvia Veneroni Marco Alessandro Pierotti Maria Grazia Daidone

PLoS One 2013 7;8(1):e53406. Epub 2013 Jan 7.

Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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July 2013

Multiparametric analysis of cell-free DNA in melanoma patients.

Authors:

Francesca Salvianti Pamela Pinzani Paolo Verderio Chiara Maura Ciniselli Daniela Massi Vincenzo De Giorgi Marta Grazzini Mario Pazzagli Claudio Orlando

PLoS One 2012 27;7(11):e49843. Epub 2012 Nov 27.

Department of Clinical Physiopathology, Clinical Biochemistry Unit, Università di Firenze, Firenze, Italy.

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June 2013

X chromosome inactivation pattern in BRCA gene mutation carriers.

Authors:

Siranoush Manoukian Paolo Verderio Silvia Tabano Patrizia Colapietro Sara Pizzamiglio Francesca R Grati Mariarosaria Calvello Bernard Peissel John Burn Valeria Pensotti Claudia Allemani Silva M Sirchia Paolo Radice Monica Miozzo

Eur J Cancer 2013 Mar 9;49(5):1136-41. Epub 2012 Nov 9.

Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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March 2013

Comment to "Non-invasive assessment of hepatic fibrosis in a series of patients with Wilson's disease".

Authors:

Paolo Verderio Chiara Maura Ciniselli Sara Pizzamiglio

Dig Liver Dis 2013 Mar 7;45(3):265. Epub 2012 Nov 7.

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March 2013

Identification of fifteen novel germline variants in the BRCA1 3'UTR reveals a variant in a breast cancer case that introduces a functional miR-103 target site.

Hum Mutat 2012 Dec 2;33(12):1665-75. Epub 2012 Aug 2.

School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, Australia.

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December 2012

Tumor response assessment by modified Choi criteria in localized high-risk soft tissue sarcoma treated with chemotherapy.

Authors:

Silvia Stacchiotti Paolo Verderio Antonella Messina Carlo Morosi Paola Collini Antonio Llombart-Bosch Javier Martin Alessandro Comandone Jurado Cruz Andrea Ferraro Giovanni Grignani Sara Pizzamiglio Vittorio Quagliuolo Piero Picci Sergio Frustaci Angelo Paolo Dei Tos Paolo G Casali Alessandro Gronchi

Cancer 2012 Dec 17;118(23):5857-66. Epub 2012 May 17.

Department of Cancer Medicine, Scientific Institute for Research and Treatment Foundation, National Cancer Institute, Milan, Italy.

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December 2012

Assessing the clinical relevance of oncogenic pathways in neoadjuvant breast cancer.

Authors:

Paolo Verderio

J Clin Oncol 2012 Jun 16;30(16):1912-5. Epub 2012 Apr 16.

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June 2012

The SNP rs895819 in miR-27a is not associated with familial breast cancer risk in Italians.

Authors:

Irene Catucci Paolo Verderio Sara Pizzamiglio Loris Bernard Valentina Dall'olio Domenico Sardella Fernando Ravagnani Laura Galastri Monica Barile Bernard Peissel Daniela Zaffaroni Siranoush Manoukian Paolo Radice Paolo Peterlongo

Breast Cancer Res Treat 2012 Jun 14;133(2):805-7. Epub 2012 Mar 14.

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June 2012

Genomic profiling by whole-genome single nucleotide polymorphism arrays in Wilms tumor and association with relapse.

Authors:

Daniela Perotti Filippo Spreafico Federica Torri Beatrice Gamba Pio D'Adamo Sara Pizzamiglio Monica Terenziani Serena Catania Paola Collini Marilina Nantron Andrea Pession Maurizio Bianchi Paolo Indolfi Paolo D'Angelo Franca Fossati-Bellani Paolo Verderio Fabio Macciardi Paolo Radice

Genes Chromosomes Cancer 2012 Jul 8;51(7):644-53. Epub 2012 Mar 8.

Department of Preventive and Predictive Medicine, Unit of Molecular Bases of Genetic Risk and Genetic Testing, Fondazione IRCCS Istituto Nazionale dei Tumori, Milano, Italy.

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July 2012

Sequencing analysis of SLX4/FANCP gene in Italian familial breast cancer cases.

Authors:

Irene Catucci Mara Colombo Paolo Verderio Loris Bernard Filomena Ficarazzi Frederique Mariette Monica Barile Bernard Peissel Elisa Cattaneo Siranoush Manoukian Paolo Radice Paolo Peterlongo

PLoS One 2012 23;7(2):e31038. Epub 2012 Feb 23.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.

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August 2012

miRNA profiling in colorectal cancer highlights miR-1 involvement in MET-dependent proliferation.

Authors:

James F Reid Viktorija Sokolova Eugenio Zoni Andrea Lampis Sara Pizzamiglio Claudia Bertan Susanna Zanutto Federica Perrone Tiziana Camerini Gianfrancesco Gallino Paolo Verderio Ermanno Leo Silvana Pilotti Manuela Gariboldi Marco A Pierotti

Mol Cancer Res 2012 Apr 16;10(4):504-15. Epub 2012 Feb 16.

Departments of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan 20133, Italy.

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April 2012

Short, full-dose adjuvant chemotherapy in high-risk adult soft tissue sarcomas: a randomized clinical trial from the Italian Sarcoma Group and the Spanish Sarcoma Group.

Authors:

Alessandro Gronchi Sergio Frustaci Mario Mercuri Javier Martin Antonio Lopez-Pousa Paolo Verderio Lidia Mariani Pinuccia Valagussa Rosalba Miceli Silvia Stacchiotti Angelo Paolo Dei Tos Antonino De Paoli Alessandra Longhi Andres Poveda Vittorio Quagliuolo Alessandro Comandone Paolo Giovanni Casali Piero Picci

J Clin Oncol 2012 Mar 6;30(8):850-6. Epub 2012 Feb 6.

Fondazione Istituto di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale Tumori, Milano, Italy.

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March 2012

Implementation of a proficiency testing for the assessment of the preanalytical phase of blood samples used for RNA based analysis.

Authors:

Kalle Günther Francesca Malentacchi Paolo Verderio Sara Pizzamiglio Chiara Maura Ciniselli Ales Tichopad Mikael Kubista Ralf Wyrich Mario Pazzagli Stefania Gelmini

Clin Chim Acta 2012 Apr 21;413(7-8):779-86. Epub 2012 Jan 21.

QIAGEN GmbH, Hilden, Germany.

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April 2012

Site-specific conjugation of ScFvs antibodies to nanoparticles by bioorthogonal strain-promoted alkyne-nitrone cycloaddition.

Authors:

Miriam Colombo Silvia Sommaruga Serena Mazzucchelli Laura Polito Paolo Verderio Patrizia Galeffi Fabio Corsi Paolo Tortora Davide Prosperi

Angew Chem Int Ed Engl 2012 Jan 25;51(2):496-9. Epub 2011 Nov 25.

NanoBioLab, Dipartimento di Biotecnologie e Bioscienze, Università di Milano Bicocca, Piazza della Scienza 2, 20126 Milano, Italy.

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January 2012

Multiple presentation of Scfv800E6 on silica nanospheres enhances targeting efficiency toward HER-2 receptor in breast cancer cells.

Authors:

Serena Mazzucchelli Paolo Verderio Silvia Sommaruga Miriam Colombo Agnese Salvadè Fabio Corsi Patrizia Galeffi Paolo Tortora Davide Prosperi

Bioconjug Chem 2011 Nov 31;22(11):2296-303. Epub 2011 Oct 31.

Dipartimento di Scienze Cliniche Luigi Sacco, Università di Milano, Ospedale L. Sacco, Via G.B. Grassi 74, Milan, Italy.

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November 2011

HER2 expression in breast cancer cells is downregulated upon active targeting by antibody-engineered multifunctional nanoparticles in mice.

Authors:

Fabio Corsi Luisa Fiandra Clara De Palma Miriam Colombo Serena Mazzucchelli Paolo Verderio Raffaele Allevi Antonella Tosoni Manuela Nebuloni Emilio Clementi Davide Prosperi

ACS Nano 2011 Aug 1;5(8):6383-93. Epub 2011 Aug 1.

Dipartimento di Scienze Cliniche Luigi Sacco, Università di Milano, Ospedale L. Sacco, via G.B. Grassi 74, 20157 Milano, Italy.

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August 2011

Methylation status in patients with early stage colon cancer: a new prognostic marker?

Authors:

Susanna Zanutto Sara Pizzamiglio Andrea Lampis Tiziana Camerini Maria G Di Mauro Marco A Pierotti Paolo Verderio Manuela Gariboldi

Int J Cancer 2012 Jan 25;130(2):488-9. Epub 2011 Apr 25.

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January 2012

Research trends for early cancer biomarker detection in Italy: an integrated program in oncology (PIO) survey.

Authors:

Paolo Verderio Anita Mangia Claudio Orlando Maurizio Belfiglio Antonio Marchetti Lucio Bertario Gennaro Chiappetta Massimo Gion Gian Paolo Tonini Franca Podo Amina Vocaturo Rosella Silvestrini Claudio Lombardo Angelo Paradiso

Tumori 2010 Sep-Oct;96(5):721-5

Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy.

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March 2011

PALB2 germline mutations in familial breast cancer cases with personal and family history of pancreatic cancer.

Authors:

Paolo Peterlongo Irene Catucci Graziella Pasquini Paolo Verderio Bernard Peissel Monica Barile Liliana Varesco Mirko Riboni Stefano Fortuzzi Siranoush Manoukian Paolo Radice

Breast Cancer Res Treat 2011 Apr 24;126(3):825-8. Epub 2010 Dec 24.

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April 2011

Investigating the structural biofunctionality of antibodies conjugated to magnetic nanoparticles.

Authors:

Emanuela Occhipinti Paolo Verderio Antonino Natalello Elisabetta Galbiati Miriam Colombo Serena Mazzucchelli Agnese Salvadè Paolo Tortora Silvia Maria Doglia Davide Prosperi

Nanoscale 2011 Feb 29;3(2):387-90. Epub 2010 Sep 29.

Dipartimento di Biotecnologie e Bioscienze, Università di Milano-Bicocca, P.za della Scienza 2, 20126, Milano, Italy.

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February 2011

Biomarkers for Early Cancer Detection - Methodological Aspects.

Authors:

Paolo Verderio Anita Mangia Chiara M Ciniselli Paola Tagliabue Angelo Paradiso

Breast Care (Basel) 2010;5(2):62-65. Epub 2010 Apr 21.

Unit of Medical Statistics and Biometry, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan.

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April 2010

Single-domain protein A-engineered magnetic nanoparticles: toward a universal strategy to site-specific labeling of antibodies for targeted detection of tumor cells.

Authors:

Serena Mazzucchelli Miriam Colombo Clara De Palma Agnese Salvadè Paolo Verderio Maria D Coghi Emilio Clementi Paolo Tortora Fabio Corsi Davide Prosperi

ACS Nano 2010 Oct;4(10):5693-702

Dipartimento di Scienze Cliniche Luigi Sacco, Università di Milano, Ospedale L. Sacco, via G.B. Grassi 74, 20157 Milano, Italy.

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October 2010

The CASP8 rs3834129 polymorphism and breast cancer risk in BRCA1 mutation carriers.

Authors:

Irene Catucci Paolo Verderio Sara Pizzamiglio Siranoush Manoukian Bernard Peissel Daniela Zaffaroni Gaia Roversi Carla B Ripamonti Barbara Pasini Monica Barile Alessandra Viel Giuseppe Giannini Laura Papi Liliana Varesco Aline Martayan Mirko Riboni Sara Volorio Paolo Radice Paolo Peterlongo

Breast Cancer Res Treat 2011 Feb 22;125(3):855-60. Epub 2010 Jul 22.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.

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February 2011

Reproducibility in the diagnosis of needle core biopsies of non-palpable breast lesions: an international study using virtual slides published on the world-wide web.

Authors:

Francesco Alfredo Zito Paolo Verderio Giovanni Simone Vito Angione Paola Apicella Simonetta Bianchi Antonio Felix Conde Omar Hameed Julio Ibarra Antony Leong Natale Pennelli Ezio Pezzica Vania Vezzosi Vincenzo Ventrella Sara Pizzamiglio Angelo Paradiso Ian Ellis

Histopathology 2010 May;56(6):720-6

Department of Pathology, National Cancer Institute 'Giovanni Paolo II', Bari, Italy.

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May 2010

Prevalidation of the rat CFU-GM assay for in vitro toxicology applications.

Authors:

Augusto Pessina Arianna Bonomi Loredana Cavicchini Beatriz Albella Laura Cerrato Dominique Parent-Massin Yann Sibiril Ralph Parchment Holger Behrsing Paolo Verderio Sara Pizzamiglio Manuela Giangreco Carolina Baglio Valentina Coccè Francesca Sisto Laura Gribaldo

Altern Lab Anim 2010 May;38(2):105-17

Department of Public Health, Microbiology, Virology, University of Milan, Italy.

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May 2010

A BRCA1 promoter variant (rs11655505) and breast cancer risk.

Authors:

Paolo Verderio Sara Pizzamiglio Melissa C Southey Amanda B Spurdle John L Hopper Xiaoqing Chen Jonathan Beesley Rita K Schmutzler Christoph Engel Barbara Burwinkel Peter Bugert Filomena Ficarazzi Siranoush Manoukian Monica Barile Barbara Wappenschmidt Georgia Chenevix-Trench Paolo Radice Paolo Peterlongo

J Med Genet 2010 Apr;47(4):268-70

Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

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April 2010

Simultaneous confidence intervals to compare gene expression profiles using ABC transporter TaqMan microfluidic cards.

Authors:

Sara Pizzamiglio Giacomo Cossa Laura Gatti Giovanni L Beretta Elisabetta Corna Stella Tinelli Paolo Verderio Paola Perego

Oncol Rep 2010 Mar;23(3):853-60

Medical Statistics and Biometry Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale Tumori, 20133 Milan, Italy.

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March 2010