Paolo Spallarossa

Paolo Spallarossa

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Paolo Spallarossa

Publications by authors named "Paolo Spallarossa"

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How Cardio-Oncology is called to prove its maturity.

Int J Cardiol 2019 Aug 22;288:130-131. Epub 2019 Mar 22.

Clinic of Cardiovascular Diseases, IRCCS San Martino Policlinic Hospital, University of Genova, Italy.

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http://dx.doi.org/10.1016/j.ijcard.2019.03.042DOI Listing
August 2019

Ivabradine in Cancer Treatment-Related Left Ventricular Dysfunction.

Chemotherapy 2018 6;63(6):315-320. Epub 2019 Mar 6.

Cardiovascular Disease Unit, San Martino Policlinic Hospital, Genoa, Italy,

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http://dx.doi.org/10.1159/000495576DOI Listing
May 2019

Identification and Management of Immune Checkpoint Inhibitor-Related Myocarditis: Use Troponin Wisely.

J Clin Oncol 2019 May 14:JCO1802464. Epub 2019 May 14.

1 Istituto di Ricovero e Cura a Carattere Scientifico Ospedale Policlinico San Martino, Genoa, Italy.

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http://dx.doi.org/10.1200/JCO.18.02464DOI Listing
May 2019

Arterial hypertension in cancer: The elephant in the room.

Int J Cardiol 2019 Apr 28;281:133-139. Epub 2019 Jan 28.

Clinic of Cardiovascular Diseases, IRCCS San Martino Policlinic Hospital, University of Genova, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01675273183556
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http://dx.doi.org/10.1016/j.ijcard.2019.01.082DOI Listing
April 2019

Early Diastolic Dysfunction after Cancer Chemotherapy: Primary Endpoint Results of a Multicenter Cardio-Oncology Study.

Chemotherapy 2018 9;63(2):55-63. Epub 2018 Feb 9.

Units of Cardiology, Hematology, Oncology, Radiation Therapy and Clinical Pharmacology, Department of Medicine, University Campus Bio-Medico, Rome, Italy.

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http://dx.doi.org/10.1159/000486761DOI Listing
June 2018

Modelling Chemotherapy-induced Cardiotoxicity by Human Pluripotent Stem Cells.

Curr Drug Targets 2017 ;18(6):719-723

Department of Medical Sciences "Mario Aresu", University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.2174/1389450117666160401125404DOI Listing
April 2018

Cardiac metastasis presenting with an ischaemic electrocardiogram pattern mimicking anterior myocardial infarction.

Eur Heart J Case Rep 2018 Mar 27;2(1):yty025. Epub 2018 Feb 27.

Clinic of Cardiovascular Diseases, San Martino Policlinic Hospital, University of Genova, Largo Rosanna Benzi, 10, 16132 Genoa, Italy.

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http://dx.doi.org/10.1093/ehjcr/yty025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426021PMC
March 2018

Current views on anthracycline cardiotoxicity.

Heart Fail Rev 2016 09;21(5):621-34

Department of Medical Sciences "Mario Aresu", University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.1007/s10741-016-9564-5DOI Listing
September 2016

Potential of creatine or phosphocreatine supplementation in cerebrovascular disease and in ischemic heart disease.

Amino Acids 2016 08 21;48(8):1955-67. Epub 2016 Jan 21.

Department of Internal Medicine and Cardionephrology, University of Genova, Genoa, Italy.

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http://dx.doi.org/10.1007/s00726-016-2173-8DOI Listing
August 2016

Pathophysiology of cardiotoxicity from target therapy and angiogenesis inhibitors.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1:S19-26

aDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumor 'Fondazione Giovanni Pascale' - IRCCS bCEINGE Biotecnologie Avanzate S.C.A.R.L cDepartment of Breast Surgery and Cancer Prevention, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS dDepartment of Molecular Medicine and Medical Biotechnology, University 'Federico II' eDepartment of Senology, Division of Breast Oncology Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS, Naples fClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa gDepartment of Medical Sciences 'Mario Aresu', University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000377DOI Listing
May 2016

Pathophysiology of anthracycline cardiotoxicity.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1:S3-S11

aCardiology Unit, University Hospital of Ferrara bDepartment of Translational Medical Sciences, Division of Internal Medicine, Federico II University, Naples cDepartment of Clinical and Biological Sciences, University of Turin, Orbassano dCardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti eChair and Division of Cardiology, University of Palermo, Palermo fU.O.C. Magnetic Resonance Imaging, Fondazione G. Monasterio C.N.R., Pisa gU.O.C. Cardiology Intensive Unit, A.O.U. Policlinico 'G. Martino', University of Messina, Messina hDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione Giovanni Pascale" -IRCCS, Naples, Italy iClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000378DOI Listing
May 2016

Preventing antiblastic drug-related cardiomyopathy: old and new therapeutic strategies.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1:S64-75

aDepartment of Medical Sciences 'Mario Aresu', University of Cagliari, Cagliari bDepartment of Translational Medical Sciences, Division of Internal Medicine, Federico II University, Naples cClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa dDepartment of Clinical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia eDepartment of General Surgery and Medical-Surgery Specialities, University of Catania, Catania fInstitute of Cardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti gDepartment of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000382DOI Listing
May 2016

A recommended practical approach to the management of anthracycline-based chemotherapy cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1:S84-92

aClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa bDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS, Naples cDepartment of Medical Sciences 'Mario Aresu', University of Cagliari dInstitute of Cardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti eCardiology Unit, University Hospital of Ferrara, Ferrara fDepartment of General Surgery and Medical-Surgery Specialties, University of Catania, Catania gChair and Division of Cardiology, University of Palermo, Palermo hDepartment of Clinical and Biological Sciences, University of Turin, Orbassano iU.O.C. Magnetic Resonance Imaging, Fondazione G. Monasterio C.N.R., Pisa jDepartment of Translational Medical Sciences, Federico II University, Naples kU.O.C. Cardiology Intensive Unit, A.O.U. Policlinico 'G. Martino', University of Messina, Messina, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000381DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927325PMC
May 2016

A recommended practical approach to the management of target therapy and angiogenesis inhibitors cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1:S93-S104

aDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS, Naples bClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa cDepartment of Medical Sciences 'Mario Aresu', University of Cagliari, Cagliari dInstitute of Cardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti eCardiology Unit, University Hospital of Ferrara, Ferrara fDepartment of General Surgery and Medical-Surgery Specialties, University of Catania, Catania gChair and Division of Cardiology, University of Palermo, Palermo hDepartment of Clinical and Biological Sciences, University of Turin, Turin iU.O.C. Magnetic Resonance Imaging, Fondazione G. Monasterio C.N.R., Pisa jDepartment of Translational Medical Sciences, Federico II University, Naples kU.O.C. Cardiology Intensive Unit, A.O.U. Policlinico 'G. Martino', University of Messina, Messina, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4927319PMC
May 2016

Cardiac toxicity of trastuzumab in elderly patients with breast cancer.

J Geriatr Cardiol 2016 May;13(4):355-63

Cardiology Unit and Laboratory of Cardiovascular Biology, AOU-IRCCS San Martino-IST and Department of Internal Medicine, University of Genova, Genova, Italy.

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http://dx.doi.org/10.11909/j.issn.1671-5411.2016.04.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4921548PMC
May 2016

Pathophysiology of anthracycline cardiotoxicity.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1 Special issue on Cardiotoxicity from Antiblastic Drugs and Cardioprotection:e3-e11

aCardiology Unit, University Hospital of Ferrara bDepartment of Translational Medical Sciences, Division of Internal Medicine, Federico II University, Naples cDepartment of Clinical and Biological Sciences, University of Turin, Orbassano dCardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti eChair and Division of Cardiology, University of Palermo, Palermo fU.O.C. Magnetic Resonance Imaging, Fondazione G. Monasterio C.N.R., Pisa gU.O.C. Cardiology Intensive Unit, A.O.U. Policlinico 'G. Martino', University of Messina, Messina hDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumori "Fondazione Giovanni Pascale" -IRCCS, Naples, Italy iClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000378DOI Listing
May 2016

Pathophysiology of cardiotoxicity from target therapy and angiogenesis inhibitors.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1 Special issue on Cardiotoxicity from Antiblastic Drugs and Cardioprotection:e19-e26

aDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumor 'Fondazione Giovanni Pascale' - IRCCS bCEINGE Biotecnologie Avanzate S.C.A.R.L cDepartment of Breast Surgery and Cancer Prevention, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS dDepartment of Molecular Medicine and Medical Biotechnology, University 'Federico II' eDepartment of Senology, Division of Breast Oncology Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS, Naples fClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa gDepartment of Medical Sciences 'Mario Aresu', University of Cagliari, Cagliari, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000377DOI Listing
May 2016

Preventing antiblastic drug-related cardiomyopathy: old and new therapeutic strategies.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1 Special issue on Cardiotoxicity from Antiblastic Drugs and Cardioprotection:e64-e75

aDepartment of Medical Sciences 'Mario Aresu', University of Cagliari, Cagliari bDepartment of Translational Medical Sciences, Division of Internal Medicine, Federico II University, Naples cClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa dDepartment of Clinical and Surgical Specialities, Radiological Sciences and Public Health, University of Brescia eDepartment of General Surgery and Medical-Surgery Specialities, University of Catania, Catania fInstitute of Cardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti gDepartment of Clinical and Biological Sciences, University of Turin, Orbassano, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000382DOI Listing
May 2016

A recommended practical approach to the management of anthracycline-based chemotherapy cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1 Special issue on Cardiotoxicity from Antiblastic Drugs and Cardioprotection:e84-e92

aClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa bDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS, Naples cDepartment of Medical Sciences 'Mario Aresu', University of Cagliari dInstitute of Cardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti eCardiology Unit, University Hospital of Ferrara, Ferrara fDepartment of General Surgery and Medical-Surgery Specialties, University of Catania, Catania gChair and Division of Cardiology, University of Palermo, Palermo hDepartment of Clinical and Biological Sciences, University of Turin, Orbassano iU.O.C. Magnetic Resonance Imaging, Fondazione G. Monasterio C.N.R., Pisa jDepartment of Translational Medical Sciences, Federico II University, Naples kU.O.C. Cardiology Intensive Unit, A.O.U. Policlinico 'G. Martino', University of Messina, Messina, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000381DOI Listing
May 2016

A recommended practical approach to the management of target therapy and angiogenesis inhibitors cardiotoxicity: an opinion paper of the working group on drug cardiotoxicity and cardioprotection, Italian Society of Cardiology.

J Cardiovasc Med (Hagerstown) 2016 May;17 Suppl 1 Special issue on Cardiotoxicity from Antiblastic Drugs and Cardioprotection:e93-e104

aDivision of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumori 'Fondazione Giovanni Pascale' - IRCCS, Naples bClinic of Cardiovascular Diseases, IRCCS San Martino IST, Genoa cDepartment of Medical Sciences 'Mario Aresu', University of Cagliari, Cagliari dInstitute of Cardiology, Center of Excellence on Aging, 'G. d'Annunzio' University, Chieti eCardiology Unit, University Hospital of Ferrara, Ferrara fDepartment of General Surgery and Medical-Surgery Specialties, University of Catania, Catania gChair and Division of Cardiology, University of Palermo, Palermo hDepartment of Clinical and Biological Sciences, University of Turin, Turin iU.O.C. Magnetic Resonance Imaging, Fondazione G. Monasterio C.N.R., Pisa jDepartment of Translational Medical Sciences, Federico II University, Naples kU.O.C. Cardiology Intensive Unit, A.O.U. Policlinico 'G. Martino', University of Messina, Messina, Italy.

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http://dx.doi.org/10.2459/JCM.0000000000000383DOI Listing
May 2016

Prevalent cardiac, renal and cardiorenal damage in patients with advanced abdominal aortic aneurysms.

Intern Emerg Med 2016 Mar 28;11(2):205-12. Epub 2015 Oct 28.

Division of Cardiology, IRCCS San Martino University Hospital-IST, Research Center of Cardiovascular Biology, University of Genova, Viale Benedetto XV, 6., 16132, Genova, Italy.

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http://link.springer.com/10.1007/s11739-015-1328-z
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http://dx.doi.org/10.1007/s11739-015-1328-zDOI Listing
March 2016

Testosterone Antagonizes Doxorubicin-Induced Senescence of Cardiomyocytes.

J Am Heart Assoc 2016 Jan 8;5(1). Epub 2016 Jan 8.

Laboratory of Cardiovascular Biology, Department of Internal Medicine, University of Genova, Italy (P.A., C.B., E.L., G.P.B., M.C., P.S., C.B., P.A.).

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http://dx.doi.org/10.1161/JAHA.115.002383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859360PMC
January 2016

Relationship between inter-arm difference in systolic blood pressure and arterial stiffness in community-dwelling older adults.

J Clin Hypertens (Greenwich) 2013 Dec 7;15(12):880-7. Epub 2013 Aug 7.

Longitudinal Studies Section, Translational Gerontology Branch, NIA/NIH, Baltimore, MD; Laboratory of Cardiovascular Sciences, Human Cardiovascular Studies Unit, NIA/NIH, Baltimore, MD; Department of Internal Medicine, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1111/jch.12178DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855278PMC
December 2013

Therapeutic use of creatine in brain or heart ischemia: available data and future perspectives.

Med Res Rev 2013 Mar 1;33(2):336-63. Epub 2011 Dec 1.

Department of Neuroscience, Opthalmology and Genetics, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1002/med.20255DOI Listing
March 2013

Soluble form of the endothelial adhesion molecule CD146 binds preferentially CD16+ monocytes.

Mol Biol Rep 2012 Jun 5;39(6):6745-52. Epub 2012 Feb 5.

Department of Internal Medicine, Cardiology, Research Center of Cardiovascular Biology, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1007/s11033-012-1499-xDOI Listing
June 2012

CD14CD16 monocyte subset levels in heart failure patients.

Dis Markers 2010 ;28(2):115-24

Division of Cardiology, Department of Internal Medicine, Research Center of Cardiovascular Biology, University of Genova, V.le Benedetto XV, 6 16132 Genova, Italy.

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http://dx.doi.org/10.3233/DMA-2010-0691DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3833331PMC
June 2010

Sublethal doses of an anti-erbB2 antibody leads to death by apoptosis in cardiomyocytes sensitized by low prosenescent doses of epirubicin: the protective role of dexrazoxane.

J Pharmacol Exp Ther 2010 Jan 19;332(1):87-96. Epub 2009 Oct 19.

Research Center of Cardiovascular Biology, Division of Cardiology, Department of Internal Medicine, University of Genova, Genova, Italy.

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http://dx.doi.org/10.1124/jpet.109.159525DOI Listing
January 2010

Doxorubicin induces senescence or apoptosis in rat neonatal cardiomyocytes by regulating the expression levels of the telomere binding factors 1 and 2.

Am J Physiol Heart Circ Physiol 2009 Dec 2;297(6):H2169-81. Epub 2009 Oct 2.

Research Center of Cardiovascular Biology, Division of Cardiology, University of Genoa, Viale Benedetto XV, 6, 16132 Genoa, Italy.

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http://dx.doi.org/10.1152/ajpheart.00068.2009DOI Listing
December 2009

Cell-cell bond modulates vascular smooth muscle cell responsiveness to Angiotensin II.

Biochem Biophys Res Commun 2009 Oct 8;388(3):523-8. Epub 2009 Aug 8.

Division of Cardiology, Department of Internal Medicine, Research Center of Cardiovascular Biology, University of Genova, Viale Benedetto XV, 6, Genova 16132, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2009.08.031DOI Listing
October 2009

Increased neutrophil lifespan in patients with congestive heart failure.

Eur J Heart Fail 2009 Apr 10;11(4):378-85. Epub 2009 Mar 10.

Department of Internal Medicine, Research Center of Cardiovascular Biology, University of Genova, Viale Benedetto XV/6, 16132 Genova, Italy.

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http://dx.doi.org/10.1093/eurjhf/hfp031DOI Listing
April 2009

Postprandial serum induces apoptosis in endothelial cells: Role of polymorphonuclear-derived myeloperoxidase and metalloproteinase-9 activity.

Atherosclerosis 2008 Jun 4;198(2):458-67. Epub 2008 Jan 4.

Research Center of Cardiovascular Biology, Division of Cardiology, Department of Internal Medicine, University of Genova, Italy.

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http://dx.doi.org/10.1016/j.atherosclerosis.2007.11.030DOI Listing
June 2008

Matrix metalloproteinase-2 and -9 are induced differently by doxorubicin in H9c2 cells: The role of MAP kinases and NAD(P)H oxidase.

Cardiovasc Res 2006 Feb 6;69(3):736-45. Epub 2005 Oct 6.

Research Center of Cardiovascular Biology, Department of Cardiology, University of Genova, Viale Benedetto XV, 6 16132 Genova, Italy.

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http://dx.doi.org/10.1016/j.cardiores.2005.08.009DOI Listing
February 2006

Doxorubicin-induced expression of LOX-1 in H9c2 cardiac muscle cells and its role in apoptosis.

Biochem Biophys Res Commun 2005 Sep;335(1):188-96

Research Center of Cardiovascular Biology, Department of Cardiology, University of Genova, Italy.

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http://dx.doi.org/10.1016/j.bbrc.2005.07.064DOI Listing
September 2005

Acute coronary syndromes do not promote prolonged in vivo FXII-dependent prothrombotic activity.

Thromb Res 2005 ;115(1-2):65-72

Division of Cardiology and Laboratory of Cardiovascular Biology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 6 16132 Genova, Italy.

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http://dx.doi.org/10.1016/j.thromres.2004.08.011DOI Listing
May 2005

Carvedilol prevents doxorubicin-induced free radical release and apoptosis in cardiomyocytes in vitro.

J Mol Cell Cardiol 2004 Oct;37(4):837-46

Laboratory of Cardiovascular Biology, Division of Cardiology, Department of Internal Medicine, University of Genova, Viale Benedetto XV, 6 Genova 16132, Italy.

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http://dx.doi.org/10.1016/j.yjmcc.2004.05.024DOI Listing
October 2004

Intense lipid peroxidation in premature clinical coronary atherosclerosis is associated with metabolic abnormalities.

J Lab Clin Med 2004 Feb;143(2):99-105

Division of Cardiology, Laboratory of Cardiovascular Biology, Department of Internal Medicine, University of Genova, Genoa, Italy.

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http://dx.doi.org/10.1016/j.lab.2003.10.009DOI Listing
February 2004