Publications by authors named "Paolo Ghia"

100Publications

Exploiting B Cell Receptor Stereotypy to design Tailored Immunotherapy in Chronic Lymphocytic Leukemia.

Clin Cancer Res 2020 Oct 13. Epub 2020 Oct 13.

Division of Experimental Oncology, Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele.

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http://dx.doi.org/10.1158/1078-0432.CCR-20-1632DOI Listing
October 2020

Higher-order connections between stereotyped subsets: implications for improved patient classification in CLL.

Blood 2020 Sep 29. Epub 2020 Sep 29.

Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.

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http://dx.doi.org/10.1182/blood.2020007039DOI Listing
September 2020

COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus.

Leukemia 2020 09 9;34(9):2354-2363. Epub 2020 Jul 9.

Università Vita-Salute San Raffaele and IRCC Ospedale San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1038/s41375-020-0959-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7347048PMC
September 2020

Relevance of Minimal Residual Disease in the Era of Targeted Agents.

Cancer J 2019 Nov/Dec;25(6):410-417

From the Strategic Research Program on CLL, IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milano, Italy.

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http://dx.doi.org/10.1097/PPO.0000000000000413DOI Listing
August 2020

The evolving treatment landscape of chronic lymphocytic leukemia.

Curr Opin Oncol 2019 11;31(6):568-573

Strategic Research Program on CLL, IRCCS Ospedale San Raffaele.

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http://dx.doi.org/10.1097/CCO.0000000000000585DOI Listing
November 2019

The importance of B cell receptor isotypes and stereotypes in chronic lymphocytic leukemia.

Leukemia 2019 02 16;33(2):287-298. Epub 2018 Dec 16.

Department of Leukemia, Unit 428, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41375-018-0303-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7182338PMC
February 2019

aberrations in chronic lymphocytic leukemia: an overview of the clinical implications of improved diagnostics.

Haematologica 2018 12 15;103(12):1956-1968. Epub 2018 Nov 15.

Internal Medicine III, Ulm University, Germany and Innere Medizin I, Universitätsklinikum des Saarlandes, Homburg, Germany.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.187583DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269313PMC
December 2018

From Mice to Men: How B Cell Immunology Helped the Understanding of Leukemia Development.

Authors:
Paolo Ghia

Front Immunol 2018 24;9:2402. Epub 2018 Oct 24.

IRCCS Ospedale San Raffaele, Università Vita-Salute San Raffaele, Milan, Italy.

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http://dx.doi.org/10.3389/fimmu.2018.02402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6209738PMC
October 2019

Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia.

Methods Mol Biol 2019 ;1881:51-62

Institute of Applied Biosciences, Center for Research and Technology, Thessaloniki, Greece.

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http://link.springer.com/10.1007/978-1-4939-8876-1_5
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http://dx.doi.org/10.1007/978-1-4939-8876-1_5DOI Listing
June 2019

Monoclonal B-cell lymphocytosis: Does the elderly patient need a specialistic approach?

Eur J Intern Med 2018 12 26;58:2-6. Epub 2018 Sep 26.

Strategic Research Program on CLL, Università Vita-Salute San Raffaele and IRCCS Ospedale San Raffaele, Milano, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S09536205183036
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http://dx.doi.org/10.1016/j.ejim.2018.09.006DOI Listing
December 2018

Splenic marginal zone lymphomas in acquired C1-inhibitor deficiency: clinical and molecular characterization.

Med Oncol 2018 Aug 2;35(9):118. Epub 2018 Aug 2.

Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Luigi Sacco Hospital Milan, Milan, Italy.

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http://dx.doi.org/10.1007/s12032-018-1183-7DOI Listing
August 2018

Minimal residual disease analysis in chronic lymphocytic leukemia: a way for achieving more personalized treatments.

Leukemia 2018 06 26;32(6):1307-1316. Epub 2018 Mar 26.

Haematological Malignancy Diagnostic Service (HMDS), Leeds Teaching Hospitals NHS Trust, Leeds and Department of Health Sciences, University of York, York, UK.

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http://www.nature.com/articles/s41375-018-0109-x
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http://dx.doi.org/10.1038/s41375-018-0109-xDOI Listing
June 2018

Highly similar genomic landscapes in monoclonal B-cell lymphocytosis and ultra-stable chronic lymphocytic leukemia with low frequency of driver mutations.

Haematologica 2018 05 15;103(5):865-873. Epub 2018 Feb 15.

Strategic Research Program on CLL and B-cell Neoplasia Unit, Division of Experimental Oncology, Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele, Milan, Italy

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http://dx.doi.org/10.3324/haematol.2017.177212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5927998PMC
May 2018

Distinct homotypic B-cell receptor interactions shape the outcome of chronic lymphocytic leukaemia.

Nat Commun 2017 06 9;8:15746. Epub 2017 Jun 9.

Biocrystallography Unit, Division of Immunology, Transplantation and Infectious Diseases, IRCCS San Raffaele Scientific Institute, via Olgettina 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1038/ncomms15746DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472768PMC
June 2017

Reactivating nuclear PTEN to treat CLL.

Oncotarget 2017 May;8(22):35486-35487

Division of Experimental Oncology, San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.

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http://dx.doi.org/10.18632/oncotarget.17543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482590PMC
May 2017

Distinct molecular genetics of chronic lymphocytic leukemia in Taiwan: clinical and pathogenetic implications.

Haematologica 2017 06 2;102(6):1085-1090. Epub 2017 Mar 2.

Strategic Research Program on CLL and B-cell Neoplasia Unit, Division of Experimental Oncology, Vita-Salute San Raffaele University and IRCCS San Raffaele Scientific Institute, Milan, Italy

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http://dx.doi.org/10.3324/haematol.2016.157552DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451340PMC
June 2017

Ibrutinib in the real world patient: many lights and some shades.

Haematologica 2016 12;101(12):1448-1450

Department of Medical Sciences, Hematology Unit. University of Ferrara, Italy.

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http://dx.doi.org/10.3324/haematol.2016.155986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5479615PMC
December 2016

Ibrutinib holds promise for patients with 17p deletion CLL.

Authors:
Paolo Ghia

Lancet Oncol 2016 10 13;17(10):1342-1343. Epub 2016 Sep 13.

Strategic Research Program on Chronic Lymphocytic Leukaemia, Division of Experimental Oncology, IRCCS Ospedale San Raffaele and Università Vita-Salute San Raffaele, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(16)30442-9DOI Listing
October 2016

Similar epidemiological trends of pre-neoplastic precursors and their respective lymphoid malignancies in Taiwan.

Ann Hematol 2016 Oct 19;95(10):1727-9. Epub 2016 Jul 19.

Department of Pathology, Chi-Mei Medical Center, Tainan, Taiwan.

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http://dx.doi.org/10.1007/s00277-016-2747-2DOI Listing
October 2016

Toll-like receptors signaling: A complex network for NF-κB activation in B-cell lymphoid malignancies.

Semin Cancer Biol 2016 08 9;39:15-25. Epub 2016 Jul 9.

Division of Experimental Oncology, IRCCS San Raffaele Hospital, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2016.07.001DOI Listing
August 2016

Chronic lymphocytic leukaemia.

Crit Rev Oncol Hematol 2016 Aug 16;104:169-82. Epub 2016 Jun 16.

Department of Onco-Haematology, Division of Experimental Oncology, IRCCS San Raffaele Hospital, Milan, Italy; University Vita-Salute San Raffaele, Milan, Italy.

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http://dx.doi.org/10.1016/j.critrevonc.2016.06.003DOI Listing
August 2016