Publications by authors named "Paolo E Porporato"

51Publications

Inflammation-induced cholestasis in cancer cachexia.

Authors:
Morgane M Thibaut Martina Sboarina Martin Roumain Sarah A Pötgens Audrey M Neyrinck Florence Destrée Justine Gillard Isabelle A Leclercq Guillaume Dachy Jean-Baptiste Demoulin Anne Tailleux Sophie Lestavel Marialetizia Rastelli Amandine Everard Patrice D Cani Paolo E Porporato Audrey Loumaye Jean-Paul Thissen Giulio G Muccioli Nathalie M Delzenne Laure B Bindels

J Cachexia Sarcopenia Muscle 2020 Dec 22. Epub 2020 Dec 22.

Metabolism and Nutrition Research Group, Louvain Drug Research Institute, UCLouvain, Université catholique de Louvain, Brussels, Belgium.

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December 2020

Iron: An Essential Element of Cancer Metabolism.

Authors:
Myriam Y Hsu Erica Mina Antonella Roetto Paolo E Porporato

Cells 2020 Dec 3;9(12). Epub 2020 Dec 3.

Molecular Biotechnology Center, Department of Molecular Biotechnology and Health Sciences, University of Torino, 10126 Turin, Italy.

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December 2020

Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential.

Authors:
Annasofia Anemone Lorena Consolino Laura Conti Pietro Irrera Myriam Y Hsu Daisy Villano Walter Dastrù Paolo E Porporato Federica Cavallo Dario Livio Longo

Br J Cancer 2021 Jan 1;124(1):207-216. Epub 2020 Dec 1.

Institute of Biostructures and Bioimaging (IBB), Italian National Research Council (CNR), Via Nizza 52, Torino, Italy.

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January 2021

Cachexia, a Systemic Disease beyond Muscle Atrophy.

Authors:
Elisabeth Wyart Laure B Bindels Erica Mina Alessio Menga Serena Stanga Paolo E Porporato

Int J Mol Sci 2020 Nov 14;21(22). Epub 2020 Nov 14.

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, 10126 Turin, Italy.

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November 2020

Editorial: Metabolism Meets Function: Untangling the Cross-Talk Between Signaling and Metabolism.

Authors:
Alessandra Castegna Daniel W McVicar Annalisa Campanella Erika M Palmieri Alessio Menga Paolo E Porporato

Front Oncol 2020 20;10:607511. Epub 2020 Oct 20.

Department of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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October 2020

Glufosinate constrains synchronous and metachronous metastasis by promoting anti-tumor macrophages.

Authors:
Alessio Menga Marina Serra Simona Todisco Carla Riera-Domingo Ummi Ammarah Manuel Ehling Erika M Palmieri Maria Antonietta Di Noia Rosanna Gissi Maria Favia Ciro L Pierri Paolo E Porporato Alessandra Castegna Massimiliano Mazzone

EMBO Mol Med 2020 Oct 4;12(10):e11210. Epub 2020 Sep 4.

Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.

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October 2020

An EPR Study Using Cyclic Hydroxylamines To Assess The Level of Mitochondrial ROS in Superinvasive Cancer Cells.

Authors:
Samantha Scheinok Tania Capeloa Paolo E Porporato Pierre Sonveaux Bernard Gallez

Cell Biochem Biophys 2020 Sep 1;78(3):249-254. Epub 2020 Jun 1.

Biomedical Magnetic Resonance, Louvain Drug Research Institute (LDRI), Université catholique de Louvain (UCLouvain), Brussels, Belgium.

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September 2020

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Adaptations and Targets in Cancer.

Authors:
Sofia Avnet Nicola Baldini Lucie Brisson Stine Falsig Pedersen Paolo E Porporato Pierre Sonveaux Gyorgy Szabadkai Silvia Pastorekova

Front Oncol 2019 28;9:1332. Epub 2019 Nov 28.

Biomedical Research Center, Slovak Academy of Sciences, Bratislava, Slovakia.

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November 2019

Monocarboxylate transporters in cancer.

Authors:
Valéry L Payen Erica Mina Vincent F Van Hée Paolo E Porporato Pierre Sonveaux

Mol Metab 2020 03 27;33:48-66. Epub 2019 Jul 27.

Pole of Pharmacology & Therapeutics, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCLouvain), Brussels, Belgium. Electronic address:

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March 2020

Pro- and antitumor effects of mitochondrial reactive oxygen species.

Authors:
Valéry L Payen Luca X Zampieri Paolo E Porporato Pierre Sonveaux

Cancer Metastasis Rev 2019 06;38(1-2):189-203

Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCLouvain), Avenue Hippocrate 57 box B1.57.04, 1200, Brussels, Belgium.

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June 2019

Assessing Metabolic Dysregulation in Muscle During Cachexia.

Authors:
Myriam Y Hsu Paolo E Porporato Elisabeth Wyart

Methods Mol Biol 2019 ;1928:337-352

Department of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.

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June 2019

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Cancer Metabolism.

Authors:
Sofia Avnet Nicola Baldini Lucie Brisson Angelo De Milito Angela M Otto Silvia Pastoreková Paolo E Porporato Gyorgy Szabadkai Pierre Sonveaux

Front Oncol 2018 3;8:329. Epub 2018 Oct 3.

Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique, Université catholique de Louvain, Brussels, Belgium.

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October 2018

Long-term antigen exposure irreversibly modifies metabolic requirements for T cell function.

Authors:
Marie Bettonville Stefania d'Aria Kathleen Weatherly Paolo E Porporato Jinyu Zhang Sabrina Bousbata Pierre Sonveaux Michel Y Braun

Elife 2018 06 18;7. Epub 2018 Jun 18.

Institute for Medical Immunology, Université Libre de Bruxelles, Gosselies, Belgium.

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June 2018

Phosphoinositide 3-Kinase Gamma Inhibition Protects From Anthracycline Cardiotoxicity and Reduces Tumor Growth.

Authors:
Mingchuan Li Valentina Sala Maria Chiara De Santis James Cimino Paola Cappello Nicola Pianca Anna Di Bona Jean Piero Margaria Miriam Martini Edoardo Lazzarini Flora Pirozzi Luca Rossi Irene Franco Julia Bornbaum Jacqueline Heger Susanne Rohrbach Alessia Perino Carlo G Tocchetti Braulio H F Lima Mauro M Teixeira Paolo E Porporato Rainer Schulz Annalisa Angelini Marco Sandri Pietro Ameri Sebastiano Sciarretta Roberto César P Lima-Júnior Marco Mongillo Tania Zaglia Fulvio Morello Francesco Novelli Emilio Hirsch Alessandra Ghigo

Circulation 2018 08;138(7):696-711

Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Italy (M.L., V.S., M.C.D.S., J.C., J.P.M., M.M., F.P., L.R., I.F., A.P., P.E.P., R.C.P.L.-J., E.H., A.G.).

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August 2018

(+)-Catechin in a 1:2 Complex with Lysine Inhibits Cancer Cell Migration and Metastatic Take in Mice.

Authors:
Valéry L Payen Paolo E Porporato Pierre Danhier Thibaut Vazeille Marine C N M Blackman Bronislav H May Paul Niebes Pierre Sonveaux

Front Pharmacol 2017 4;8:869. Epub 2017 Dec 4.

Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Brussels, Belgium.

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December 2017

Presenilin 2-Dependent Maintenance of Mitochondrial Oxidative Capacity and Morphology.

Authors:
Sabrina Contino Paolo E Porporato Matthew Bird Claudia Marinangeli Rémi Opsomer Pierre Sonveaux Françoise Bontemps Ilse Dewachter Jean-Noël Octave Luc Bertrand Serena Stanga Pascal Kienlen-Campard

Front Physiol 2017 12;8:796. Epub 2017 Oct 12.

Alzheimer Research Group, Institute of Neuroscience, Université catholique de Louvain, Brussels, Belgium.

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October 2017

Ffar2 expression regulates leukaemic cell growth in vivo.

Authors:
Laure B Bindels Paolo E Porporato Sarah Ducastel Martina Sboarina Audrey M Neyrinck Evelyne M Dewulf Olivier Feron Sophie Lestavel Patrice D Cani Bart Staels Pierre Sonveaux Nathalie M Delzenne

Br J Cancer 2017 Oct 5;117(9):1336-1340. Epub 2017 Sep 5.

Metabolism and Nutrition Research Group, Louvain Drug Research Institute, Université Catholique de Louvain, Avenue Mounier 73, Box B1.73.11, Brussels 1200, Belgium.

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October 2017

MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases.

Authors:
Silvia Lemma Gemma Di Pompo Paolo E Porporato Martina Sboarina Shonagh Russell Robert J Gillies Nicola Baldini Pierre Sonveaux Sofia Avnet

Biochim Biophys Acta Mol Basis Dis 2017 12 1;1863(12):3254-3264. Epub 2017 Sep 1.

Orthopaedic Pathophysiology and Regenerative Medicine Unit, Istituto Ortopedico Rizzoli, Bologna, Italy. Electronic address:

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December 2017

Monocarboxylate Transporter MCT1 Promotes Tumor Metastasis Independently of Its Activity as a Lactate Transporter.

Authors:
Valéry L Payen Myriam Y Hsu Kristin S Rädecke Elisabeth Wyart Thibaut Vazeille Caroline Bouzin Paolo E Porporato Pierre Sonveaux

Cancer Res 2017 10 21;77(20):5591-5601. Epub 2017 Aug 21.

Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Brussels, Belgium.

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October 2017

Annual Meeting of the International Society of Cancer Metabolism (ISCaM): Metabolic Networks in Cancer.

Authors:
Nicola Baldini Angelo De Milito Olivier Feron Robert J Gillies Carine Michiels Angela M Otto Silvia Pastoreková Stine F Pedersen Paolo E Porporato Pierre Sonveaux Claudiu T Supuran Sofia Avnet

Front Pharmacol 2017 4;8:411. Epub 2017 Jul 4.

Rizzoli Orthopaedic InstituteBologna, Italy.

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July 2017

Cancer metabolism in space and time: Beyond the Warburg effect.

Authors:
Pierre Danhier Piotr Bański Valéry L Payen Debora Grasso Luigi Ippolito Pierre Sonveaux Paolo E Porporato

Biochim Biophys Acta Bioenerg 2017 Aug 4;1858(8):556-572. Epub 2017 Feb 4.

Pole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Avenue Emmanuel Mounier 52 box B1.53.09, 1200 Brussels, Belgium; Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Torino, Via Nizza 52, 10126 Torino Italy. Electronic address:

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August 2017

Multimodality Imaging Identifies Distinct Metabolic Profiles In Vitro and In Vivo.

Authors:
Marie-Aline Neveu Géraldine De Preter Valérie Marchand Anne Bol Jeffery R Brender Keita Saito Shun Kishimoto Paolo E Porporato Pierre Sonveaux Vincent Grégoire Olivier Feron Bénédicte F Jordan Murali C Krishna Bernard Gallez

Neoplasia 2016 Dec 24;18(12):742-752. Epub 2016 Nov 24.

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain, Brussels, Belgium. Electronic address:

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December 2016

Lactate Dehydrogenase B Controls Lysosome Activity and Autophagy in Cancer.

Authors:
Lucie Brisson Piotr Bański Martina Sboarina Coralie Dethier Pierre Danhier Marie-Joséphine Fontenille Vincent F Van Hée Thibaut Vazeille Morgane Tardy Jorge Falces Caroline Bouzin Paolo E Porporato Raphaël Frédérick Carine Michiels Tamara Copetti Pierre Sonveaux

Cancer Cell 2016 09;30(3):418-431

Institut de Recherche Expérimentale et Clinique (IREC), Pole of Pharmacology, Université catholique de Louvain (UCL), 1200 Brussels, Belgium. Electronic address:

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September 2016

Energy metabolism in osteoclast formation and activity.

Authors:
Silvia Lemma Martina Sboarina Paolo E Porporato Nicoletta Zini Pierre Sonveaux Gemma Di Pompo Nicola Baldini Sofia Avnet

Int J Biochem Cell Biol 2016 10 30;79:168-180. Epub 2016 Aug 30.

Orthopaedic Pathophysiology and Regenerative Medicine Unit, Istituto Ortopedico Rizzoli (IOR), via di Barbiano 1/10, 40136 Bologna, Italy. Electronic address:

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October 2016

Paving the way for therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide.

Authors:
Paolo E Porporato Pierre Sonveaux

Mol Cell Oncol 2015 Jul-Sep;2(3):e968043. Epub 2014 Oct 29.

Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC); Université catholique de Louvain (UCL) ; Brussels, Belgium.

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June 2016

Direct Evidence of the Link Between Energetic Metabolism and Proliferation Capacity of Cancer Cells In Vitro.

Authors:
Géraldine De Preter Pierre Danhier Paolo E Porporato Valéry L Payen Bénédicte F Jordan Pierre Sonveaux Bernard Gallez

Adv Exp Med Biol 2016 ;876:209-214

Biomedical Magnetic Resonance Research Group, Université catholique de Louvain (UCL), Avenue Mounier 73 (B1.73.08), 1200, Brussels, Belgium.

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May 2016

Application of Electron Paramagnetic Resonance (EPR) Oximetry to Monitor Oxygen in Wounds in Diabetic Models.

Authors:
Céline M Desmet Aurore Lafosse Sophie Vériter Paolo E Porporato Pierre Sonveaux Denis Dufrane Philippe Levêque Bernard Gallez

PLoS One 2015 14;10(12):e0144914. Epub 2015 Dec 14.

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.

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July 2016

Metabolic changes associated with tumor metastasis, part 2: Mitochondria, lipid and amino acid metabolism.

Authors:
Paolo E Porporato Valéry L Payen Bjorn Baselet Pierre Sonveaux

Cell Mol Life Sci 2016 Apr 8;73(7):1349-63. Epub 2015 Dec 8.

Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Avenue Emmanuel Mounier 52, box B1.53.09, 1200, Brussels, Belgium.

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April 2016

Lactate promotes glutamine uptake and metabolism in oxidative cancer cells.

Authors:
Jhudit Pérez-Escuredo Rajesh K Dadhich Suveera Dhup Andrea Cacace Vincent F Van Hée Christophe J De Saedeleer Martina Sboarina Fabien Rodriguez Marie-Joséphine Fontenille Lucie Brisson Paolo E Porporato Pierre Sonveaux

Cell Cycle 2016 ;15(1):72-83

a From the Pole of Pharmacology, Institute of Experimental and Clinical Research (IREC), Université catholique de Louvain (UCL) Medical School , Brussels , Belgium.

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October 2016

Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway.

Authors:
Valéry L Payen Paolo E Porporato Bjorn Baselet Pierre Sonveaux

Cell Mol Life Sci 2016 Apr 1;73(7):1333-48. Epub 2015 Dec 1.

Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL), Avenue Emmanuel Mounier 52, box B1.53.09, 1200, Brussels, Belgium.

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April 2016

Non-invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism.

Authors:
Lionel Mignion Pierre Danhier Julie Magat Paolo E Porporato Julien Masquelier Vincent Gregoire Giulio G Muccioli Pierre Sonveaux Bernard Gallez Bénédicte F Jordan

Int J Cancer 2016 Apr 9;138(8):2043-9. Epub 2015 Dec 9.

Biomedical Magnetic Resonance Group, Louvain Drug Research Institute, Université Catholique De Louvain (UCL), Avenue Mounier, 73 Box B1.73.08, Brussels, Belgium.

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April 2016

Inhibition of the pentose phosphate pathway by dichloroacetate unravels a missing link between aerobic glycolysis and cancer cell proliferation.

Authors:
Géraldine De Preter Marie-Aline Neveu Pierre Danhier Lucie Brisson Valéry L Payen Paolo E Porporato Bénédicte F Jordan Pierre Sonveaux Bernard Gallez

Oncotarget 2016 Jan;7(3):2910-20

Louvain Drug Research Institute (LDRI), Biomedical Magnetic Resonance Research Group, Université Catholique de Louvain (UCL), Brussels, Belgium.

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January 2016

In vivo visualization and ex vivo quantification of murine breast cancer cells in the mouse brain using MRI cell tracking and electron paramagnetic resonance.

Authors:
Pierre Danhier Julie Magat Philippe Levêque Géraldine De Preter Paolo E Porporato Caroline Bouzin Bénédicte F Jordan Gladys Demeur Vincent Haufroid Olivier Feron Pierre Sonveaux Bernard Gallez

NMR Biomed 2015 Mar 22;28(3):367-75. Epub 2015 Jan 22.

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.

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March 2015

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing.

Authors:
Kiran Kumar Chereddy Charles-Henry Her Michela Comune Claudia Moia Alessandra Lopes Paolo E Porporato Julie Vanacker Martin C Lam Lars Steinstraesser Pierre Sonveaux Huijun Zhu Lino S Ferreira Gaëlle Vandermeulen Véronique Préat

J Control Release 2014 Nov 27;194:138-47. Epub 2014 Aug 27.

Université catholique de Louvain, Louvain Drug Research Institute (LDRI), Advanced Drug Delivery and Biomaterials, Avenue E. Mounier 73 box B1.73.12, 1200 Brussels, Belgium. Electronic address:

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November 2014

A mitochondrial switch promotes tumor metastasis.

Authors:
Paolo E Porporato Valéry L Payen Jhudit Pérez-Escuredo Christophe J De Saedeleer Pierre Danhier Tamara Copetti Suveera Dhup Morgane Tardy Thibaut Vazeille Caroline Bouzin Olivier Feron Carine Michiels Bernard Gallez Pierre Sonveaux

Cell Rep 2014 Aug 24;8(3):754-66. Epub 2014 Jul 24.

Institut de Recherche Expérimentale et Clinique (IREC), Pole of Pharmacology (FATH), Université catholique de Louvain (UCL), Brussels 1200, Belgium. Electronic address:

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August 2014

Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation.

Authors:
Vanesa Bol Anne Bol Caroline Bouzin Daniel Labar John A Lee Guillaume Janssens Paolo E Porporato Pierre Sonveaux Olivier Feron Vincent Grégoire

Acta Oncol 2015 Feb 9;54(2):266-74. Epub 2014 Jul 9.

Center for Molecular Imaging, Radiotherapy and Oncology, Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain (UCL) , Brussels , Belgium.

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February 2015

Multimodal cell tracking of a spontaneous metastasis model: comparison between MRI, electron paramagnetic resonance and bioluminescence.

Authors:
Pierre Danhier Géraldine De Preter Julie Magat Quentin Godechal Paolo E Porporato Bénédicte F Jordan Olivier Feron Pierre Sonveaux Bernard Gallez

Contrast Media Mol Imaging 2014 Mar-Apr;9(2):143-53

Louvain Drug Research Institute, Biomedical Magnetic Resonance Research Group, Université catholique de Louvain, Brussels, Belgium.

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October 2014

Skin electroporation of a plasmid encoding hCAP-18/LL-37 host defense peptide promotes wound healing.

Authors:
Lars Steinstraesser Martin C Lam Frank Jacobsen Paolo E Porporato Kiran Kumar Chereddy Mustafa Becerikli Ingo Stricker Robert Ew Hancock Marcus Lehnhardt Pierre Sonveaux Véronique Préat Gaëlle Vandermeulen

Mol Ther 2014 Apr 5;22(4):734-42. Epub 2013 Dec 5.

Louvain Drug Research Institute, Pharmaceutics and Drug Delivery, Université catholique de Louvain, Brussels, Belgium.

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April 2014

Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells.

Authors:
Carole de Meester Aurélie D Timmermans Magali Balteau Audrey Ginion Véronique Roelants Gauthier Noppe Paolo E Porporato Pierre Sonveaux Benoît Viollet Kei Sakamoto Olivier Feron Sandrine Horman Jean-Louis Vanoverschelde Christophe Beauloye Luc Bertrand

Cardiovasc Res 2014 Jan 8;101(1):20-9. Epub 2013 Oct 8.

Pôle de Recherche Cardiovasculaire, Université catholique de Louvain, Institut de Recherche Expérimentale et Clinique, Avenue Hippocrate, 55, B1.55.05, Brussels B-1200, Belgium.

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January 2014

Optimization of tumor radiotherapy with modulators of cell metabolism: toward clinical applications.

Authors:
Pierre Danhier Christophe J De Saedeleer Oussama Karroum Géraldine De Preter Paolo E Porporato Bénédicte F Jordan Bernard Gallez Pierre Sonveaux

Semin Radiat Oncol 2013 Oct;23(4):262-72

Biomedical Magnetic Resonance Research Group, Louvain Drug Research Institute (LDRI), Université catholique de Louvain (UCL) Medical School, Brussels, Belgium; Pole of Pharmacology, Institut de Recherche Expérimentale et Clinique (IREC), Université catholique de Louvain (UCL) Medical School, Brussels, Belgium.

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October 2013

Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice.

Authors:
Paolo E Porporato Nicoletta Filigheddu Simone Reano Michele Ferrara Elia Angelino Viola F Gnocchi Flavia Prodam Giulia Ronchi Sharmila Fagoonee Michele Fornaro Federica Chianale Gianluca Baldanzi Nicola Surico Fabiola Sinigaglia Isabelle Perroteau Roy G Smith Yuxiang Sun Stefano Geuna Andrea Graziani

J Clin Invest 2013 Feb 2;123(2):611-22. Epub 2013 Jan 2.

Department of Translational Medicine, Interdisciplinary Research Center of Autoimmune Diseases (IRCAD), and Biotechnology Center for Applied Medical Research (BRMA), Università del Piemonte Orientale "Amedeo Avogadro" — Alessandria, Novara, Vercelli, Italy.

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February 2013

Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells.

Authors:
Christophe J De Saedeleer Tamara Copetti Paolo E Porporato Julien Verrax Olivier Feron Pierre Sonveaux

PLoS One 2012 17;7(10):e46571. Epub 2012 Oct 17.

Pole of Pharmacology, Institut de Recherches Expérimentales et Cliniques (IREC), Université catholique de Louvain (UCL), Brussels, Belgium.

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April 2013

Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice.

Authors:
Paolo E Porporato Valéry L Payen Christophe J De Saedeleer Véronique Préat Jean-Paul Thissen Olivier Feron Pierre Sonveaux

Angiogenesis 2012 Dec 3;15(4):581-92. Epub 2012 Jun 3.

Pole of Pharmacology, Université catholique de Louvain (UCL), Avenue Emmanuel Mounier 53 box B1.53.09, 1200, Brussels, Belgium.

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December 2012

SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.

Authors:
Gianluca Baldanzi Andrea Pighini Valentina Bettio Elena Rainero Sara Traini Federica Chianale Paolo E Porporato Nicoletta Filigheddu Riccardo Mesturini Shuping Song Tamas Schweighoffer Laura Patrussi Cosima T Baldari Xiao-Ping Zhong Wim J van Blitterswijk Fabiola Sinigaglia Kim E Nichols Ignacio Rubio Ornella Parolini Andrea Graziani

J Immunol 2011 Dec 2;187(11):5941-51. Epub 2011 Nov 2.

Department of Clinical and Experimental Medicine, University A. Avogadro of Piemonte Orientale, 28100 Novara, Italy.

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December 2011

Anticancer targets in the glycolytic metabolism of tumors: a comprehensive review.

Authors:
Paolo E Porporato Suveera Dhup Rajesh K Dadhich Tamara Copetti Pierre Sonveaux

Front Pharmacol 2011 25;2:49. Epub 2011 Aug 25.

Pole of Pharmacology and Therapeutics, Institute of Experimental and Clinical Research, University of Louvain Medical School Brussels, Belgium.

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November 2011

Diacylglycerol kinase α mediates 17-β-estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30.

Authors:
Nicoletta Filigheddu Sara Sampietro Federica Chianale Paolo E Porporato Miriam Gaggianesi Ilaria Gregnanin Elena Rainero Michele Ferrara Beatrice Perego Francesca Riboni Gianluca Baldanzi Andrea Graziani Nicola Surico

Cell Signal 2011 Dec 22;23(12):1988-96. Epub 2011 Jul 22.

Department of Clinical and Experimental Medicine and Biotechnology Center for Applied Medical Research, University of Piemonte Orientale Amedeo Avogadro, Novara, Italy.

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December 2011

NADPH oxidase-mediated reactive oxygen species production activates hypoxia-inducible factor-1 (HIF-1) via the ERK pathway after hyperthermia treatment.

Authors:
Eui Jung Moon Pierre Sonveaux Paolo E Porporato Pierre Danhier Bernard Gallez Ines Batinic-Haberle Yu-Chih Nien Thies Schroeder Mark W Dewhirst

Proc Natl Acad Sci U S A 2010 Nov 8;107(47):20477-82. Epub 2010 Nov 8.

Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA.

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November 2010

Differential expression of microRNAs between eutopic and ectopic endometrium in ovarian endometriosis.

Authors:
Nicoletta Filigheddu Ilaria Gregnanin Paolo E Porporato Daniela Surico Beatrice Perego Licia Galli Claudia Patrignani Andrea Graziani Nicola Surico

J Biomed Biotechnol 2010 10;2010:369549. Epub 2010 Mar 10.

Laboratory of Oncological Gynecology, Department of Clinical and Experimental Medicine, and Biotechnology Center for Applied Medical Research, University of Piemonte Orientale Amedeo Avogadro, 28100 Novara, Italy.

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June 2010

Diacylglycerol kinase alpha mediates HGF-induced Rac activation and membrane ruffling by regulating atypical PKC and RhoGDI.

Authors:
Federica Chianale Elena Rainero Cristina Cianflone Valentina Bettio Andrea Pighini Paolo E Porporato Nicoletta Filigheddu Guido Serini Fabiola Sinigaglia Gianluca Baldanzi Andrea Graziani

Proc Natl Acad Sci U S A 2010 Mar 16;107(9):4182-7. Epub 2010 Feb 16.

Department of Clinical and Experimental Medicine and Biotecnologie per la Ricerca Medica Applicata, University Amedeo Avogadro of Piemonte Orientale, 28100 Novara, Italy.

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March 2010

Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling.

Authors:
Federica Chianale Santina Cutrupi Elena Rainero Gianluca Baldanzi Paolo E Porporato Sara Traini Nicoletta Filigheddu Viola F Gnocchi Massimo M Santoro Ornella Parolini Wim J van Blitterswijk Fabiola Sinigaglia Andrea Graziani

Mol Biol Cell 2007 Dec 26;18(12):4859-71. Epub 2007 Sep 26.

Department of Medical Sciences, University of Piemonte Orientale "A. Avogadro," 28100 Novara, Italy.

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December 2007

Ghrelin and des-acyl ghrelin promote differentiation and fusion of C2C12 skeletal muscle cells.

Authors:
Nicoletta Filigheddu Viola F Gnocchi Marco Coscia Miriam Cappelli Paolo E Porporato Riccardo Taulli Sara Traini Gianluca Baldanzi Federica Chianale Santina Cutrupi Elisa Arnoletti Corrado Ghè Alberto Fubini Nicola Surico Fabiola Sinigaglia Carola Ponzetto Giampiero Muccioli Tiziana Crepaldi Andrea Graziani

Mol Biol Cell 2007 Mar 3;18(3):986-94. Epub 2007 Jan 3.

Department of Medical Sciences, University of Piemonte Orientale, 28100 Novara, Italy.

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March 2007