Paolo Chieffi

Paolo Chieffi

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Paolo Chieffi

Publications by authors named "Paolo Chieffi"

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Extragonadal germ cell tumors: Not just a matter of location. A review about clinical, molecular and pathological features.

Cancer Med 2019 Sep 30. Epub 2019 Sep 30.

Pathology Unit, Department of Mental and Physical Health and Preventive Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

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http://dx.doi.org/10.1002/cam4.2195DOI Listing
September 2019

An up-date on novel molecular targets in testicular germ cell tumors subtypes.

Authors:
Paolo Chieffi

Intractable Rare Dis Res 2019 May;8(2):161-164

Dipartimento di Psicologia, Università della Campania, Caserta, Italy.

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http://dx.doi.org/10.5582/irdr.2019.01055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6557231PMC
May 2019

AMPA receptor expression in mouse testis and spermatogonial GC-1 cells: A study on its regulation by excitatory amino acids.

J Cell Biochem 2019 Feb 14. Epub 2019 Feb 14.

Department of Environmental, Biological, and Pharmaceutical Sciences & Technologies, University of Campania "L. Vanvitelli", Caserta, Italy.

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http://dx.doi.org/10.1002/jcb.28382DOI Listing
February 2019

New Anti-Cancer Strategies in Testicular Germ Cell Tumors.

Recent Pat Anticancer Drug Discov 2019 ;14(1):53-59

Institute of Endocrinology and Experimental Oncology of the CNR c / o Department of Molecular Medicine and Medical Biotechnology, School of Medicine and Surgery of Naples, University of Naples 'Federico II', Naples, Italy.

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http://www.eurekaselect.com/168893/article
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http://dx.doi.org/10.2174/1574892814666190111120023DOI Listing
January 2019

Aurora B: A new promising therapeutic target in cancer.

Authors:
Paolo Chieffi

Intractable Rare Dis Res 2018 May;7(2):141-144

Dipartimento di Psicologia, Università della Campania, Caserta, Italy.

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http://dx.doi.org/10.5582/irdr.2018.01018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5982624PMC
May 2018

Recent Advances in New Discovered Molecular Targets in Testicular Germ Cell Tumors.

Authors:
Paolo Chieffi

Curr Med Chem 2018 Feb;25(5):575-583

Dipartimento di Psicologia, Universita degli Studi della Campania, 81100 Caserta, Italy.

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http://dx.doi.org/10.2174/0929867324666171003115807DOI Listing
February 2018

An up-date on epigenetic and molecular markers in testicular germ cell tumors.

Authors:
Paolo Chieffi

Intractable Rare Dis Res 2017 Nov;6(4):319-321

Dipartimento di Psicologia, Università della Campania, Caserta, Italy.

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http://dx.doi.org/10.5582/irdr.2017.01070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5735289PMC
November 2017

Testicular cancer from diagnosis to epigenetic factors.

Oncotarget 2017 Nov 18;8(61):104654-104663. Epub 2017 Sep 18.

Progetto ONCONET 2.0, Linea progettuale 14 per l'implementazione della prevenzione e diagnosi precoce del tumore alla prostata e testicolo, Regione Campania, Italy.

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http://dx.doi.org/10.18632/oncotarget.20992DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732834PMC
November 2017

An Overview on Predictive Biomarkers of Testicular Germ Cell Tumors.

Authors:
Paolo Chieffi

J Cell Physiol 2017 Feb 29;232(2):276-280. Epub 2016 Jul 29.

Dipartimento di Psicologia, Seconda Università di Napoli, Caserta, Italy.

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http://dx.doi.org/10.1002/jcp.25482DOI Listing
February 2017

New perspective on molecular markers as promising therapeutic targets in germ cell tumors.

Authors:
Paolo Chieffi

Intractable Rare Dis Res 2016 May;5(2):137-9

Dipartimento di Psicologia, Seconda Università di Napoli, Caserta, Italy.

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http://dx.doi.org/10.5582/irdr.2016.01007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4869583PMC
May 2016

D-Aspartate Induces Proliferative Pathways in Spermatogonial GC-1 Cells.

J Cell Physiol 2016 Feb;231(2):490-5

Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università di Napoli, Caserta, Italy.

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http://doi.wiley.com/10.1002/jcp.25095
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http://dx.doi.org/10.1002/jcp.25095DOI Listing
February 2016

Recent advances in molecular and cell biology of testicular germ-cell tumors.

Authors:
Paolo Chieffi

Int Rev Cell Mol Biol 2014 ;312:79-100

Department of Psychology II, University of Naples, Caserta, Italy. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/B97801280017830
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http://dx.doi.org/10.1016/B978-0-12-800178-3.00003-8DOI Listing
June 2015

High levels of GPR30 protein in human testicular carcinoma in situ and seminomas correlate with low levels of estrogen receptor-beta and indicate a switch in estrogen responsiveness.

J Cell Physiol 2015 Jun;230(6):1290-7

Dipartimento di Neuroscienze e Scienze Riproduttive ed Odontostomatologiche, Università di Napoli "Federico II,", Naples, Italy.

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http://dx.doi.org/10.1002/jcp.24864DOI Listing
June 2015

An up-date on newly discovered immunohistochemical biomarkers for the diagnosis of human testicular germ cell tumors.

Histol Histopathol 2014 Aug 13;29(8):999-1006. Epub 2014 Mar 13.

Department of Experimental Medicine, II University of Naples, Naples, Italy.

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http://dx.doi.org/10.14670/HH-29.999DOI Listing
August 2014

The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival.

Nucleic Acids Res 2014 Mar 24;42(5):3218-27. Epub 2013 Dec 24.

Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', Rome, Italy, Laboratories of Neuroembryology and of Cellular and Molecular Neurobiology, Fondazione Santa Lucia IRCCS, 00143 Rome, Italy, Department of Psychology, II University of Naples, Caserta, Italy, Department of Functional Genomics and Cancer, Institut de Genetique et de Biologie Moleculaire et Cellulaire, F-67400, INSERM U964, F-67400 Illkirch, France and Department of Health Sciences, University of Rome Foro Italico, Rome, Italy.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkt1307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950702PMC
March 2014

D-aspartate affects NMDA receptor-extracellular signal-regulated kinase pathway and upregulates androgen receptor expression in the rat testis.

Theriogenology 2014 Mar 18;81(5):744-51. Epub 2013 Dec 18.

Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università di Napoli, Caserta, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.theriogenology.2013.12.009DOI Listing
March 2014

Molecular biomarkers as potential targets for therapeutic strategies in human testicular germ cell tumors: an overview.

J Cell Physiol 2013 Aug;228(8):1641-6

Dipartimento di Psicologia, II Università di Napoli, Caserta, Italy.

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http://dx.doi.org/10.1002/jcp.24328DOI Listing
August 2013

Embryonic defects and growth alteration in mice with homozygous disruption of the Patz1 gene.

J Cell Physiol 2013 Mar;228(3):646-53

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR and Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1002/jcp.24174DOI Listing
March 2013

The high-mobility group A1-estrogen receptor β nuclear interaction is impaired in human testicular seminomas.

J Cell Physiol 2012 Dec;227(12):3749-55

Dipartimento di Medicina Sperimentale, II Università di Napoli, Via Costantinopoli, Naples, Italy.

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http://doi.wiley.com/10.1002/jcp.24087
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http://dx.doi.org/10.1002/jcp.24087DOI Listing
December 2012

GPR30 is overexpressed in post-puberal testicular germ cell tumors.

Cancer Biol Ther 2011 Mar 15;11(6):609-13. Epub 2011 Mar 15.

Istituto Nazionale dei Tumori "Fondazione G. Pascale" , Università di Napoli “Federico II”, Naples, Italy.

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http://dx.doi.org/10.4161/cbt.11.6.14672DOI Listing
March 2011

AZD1152 negatively affects the growth of anaplastic thyroid carcinoma cells and enhances the effects of oncolytic virus dl922-947.

Endocr Relat Cancer 2011 Feb 13;18(1):129-41. Epub 2011 Jan 13.

Dipartimento di Biologia e Patologia Cellulare e Molecolare, Facoltà di Medicina e Chirurgia, Università di Napoli Federico II, Via S. Pansini 5, 80131 Napoli, Italy.

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http://dx.doi.org/10.1677/ERC-10-0234DOI Listing
February 2011

Leptin modulates the survival of autoreactive CD4+ T cells through the nutrient/energy-sensing mammalian target of rapamycin signaling pathway.

J Immunol 2010 Dec 15;185(12):7474-9. Epub 2010 Nov 15.

Laboratorio di Immunologia, Istituto di Endocrinologia e Oncologia Sperimentale, Consiglio Nazionale delle Ricerche, Napoli, Italy.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1001674
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http://dx.doi.org/10.4049/jimmunol.1001674DOI Listing
December 2010

Resveratrol regulates p66Shc activation in HaCaT cells.

Exp Dermatol 2010 Oct;19(10):895-903

Department of Systematic Pathology, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1111/j.1600-0625.2010.01117.xDOI Listing
October 2010

High-mobility group A1 proteins regulate p53-mediated transcription of Bcl-2 gene.

Cancer Res 2010 Jul 8;70(13):5379-88. Epub 2010 Jun 8.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Università degli Studi di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-4199DOI Listing
July 2010

Molecular and cell biology of testicular germ cell tumors.

Int Rev Cell Mol Biol 2009 ;278:277-308

Dipartimento di Medicina Sperimentale, II Università di Napoli, 80138 Naples, Italy.

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http://dx.doi.org/10.1016/S1937-6448(09)78006-2DOI Listing
December 2009

Aurora B expression in post-puberal testicular germ cell tumours.

J Cell Physiol 2009 Nov;221(2):435-9

Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1002/jcp.21875DOI Listing
November 2009

Interaction between HMGA1 and retinoblastoma protein is required for adipocyte differentiation.

J Biol Chem 2009 Sep 26;284(38):25993-6004. Epub 2009 Jul 26.

Istituto di Endocrinologia ed Oncologia Sperimentale del Consiglio Nazionale delle Ricerche, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli Federico II, Via S. Pansini 5, 80131 Naples, Italy.

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http://dx.doi.org/10.1074/jbc.M109.034280DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758000PMC
September 2009

Overexpression of chromatin assembly factor-1 (CAF-1) p60 is predictive of adverse behaviour of prostatic cancer.

Histopathology 2009 Apr 20;54(5):580-9. Epub 2009 Mar 20.

Department of Biomorphological and Functional Sciences, Pathology Section, University of Naples Federico II, Naples, Italy.

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http://dx.doi.org/10.1111/j.1365-2559.2009.03266.xDOI Listing
April 2009

Increased expression and nuclear localization of the centrosomal kinase Nek2 in human testicular seminomas.

J Pathol 2009 Feb;217(3):431-41

Department of Public Health and Cell Biology, University of Rome Tor Vergata, 00133 Rome, Italy.

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http://doi.wiley.com/10.1002/path.2471
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http://dx.doi.org/10.1002/path.2471DOI Listing
February 2009

HMGA1 protein is a novel target of the ATM kinase.

Eur J Cancer 2008 Nov 8;44(17):2668-79. Epub 2008 Sep 8.

Istituto di Endocrinologia ed Oncologia Sperimentale del CNR c/o Dipartimento di Biologia e Patologia Cellulare e Molecolare, Facoltà di Medicina e Chirurgia di Napoli, Università degli Studi di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1016/j.ejca.2008.07.033DOI Listing
November 2008

The Mia/Cd-rap gene expression is downregulated by the high-mobility group A proteins in mouse pituitary adenomas.

Endocr Relat Cancer 2007 Sep;14(3):875-86

Dipartimento di Biologia e Patologia Cellulare e Molecolare and Istituto di Endocrinologia ed Oncologia Sperimentale del CNR, University of Naples Federico II, via Pansini 5, 80131 Naples, Italy.

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http://erc.endocrinology-journals.org/cgi/doi/10.1677/ERC-07
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http://dx.doi.org/10.1677/ERC-07-0036DOI Listing
September 2007

Molecular targets for the treatment of testicular germ cell tumors.

Authors:
Paolo Chieffi

Mini Rev Med Chem 2007 Jul;7(7):755-9

Dipartimento di Medicina Sperimentale, II Università di Napoli, Napoli, Italy.

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http://dx.doi.org/10.2174/138955707781024472DOI Listing
July 2007

Loss of proline-rich tyrosine kinase 2 function induces spreading and motility of epithelial prostate cells.

J Cell Physiol 2006 Oct;209(1):74-80

Dipartimento Farmaco-Biologico, Università della Calabria Arcavacata, Cosenza, Italy.

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http://dx.doi.org/10.1002/jcp.20709DOI Listing
October 2006

17beta-estradiol induces Akt-1 through estrogen receptor-beta in the frog (Rana esculenta) male germ cells.

Reproduction 2006 Sep;132(3):477-84

Dipartimento di Medicina Sperimentale, II Università di Napoli, Via Costantinopoli, 16, 80138 Napoli, Naples, Italy.

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https://rep.bioscientifica.com/view/journals/rep/132/3/13204
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http://dx.doi.org/10.1530/rep.1.01107DOI Listing
September 2006

17-beta-estradiol elicits genomic and non-genomic responses in mouse male germ cells.

J Cell Physiol 2006 Jan;206(1):238-45

Department of Histology and Medical Embriology, University of Rome La Sapienza, Rome, Italy.

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http://dx.doi.org/10.1002/jcp.20454DOI Listing
January 2006

D-aspartate modulates transcriptional activity in Harderian gland of frog, Rana esculenta: Morphological and molecular evidence.

J Cell Physiol 2005 Aug;204(2):445-54

Dip. Scienze della Vita, Seconda Università di Napoli, via Vivaldi, Caserta, Italy.

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http://dx.doi.org/10.1002/jcp.20316DOI Listing
August 2005

Estrogen-induced Akt-1 activity in the lizard (Podarcis s. sicula) testis.

Mol Reprod Dev 2005 May;71(1):52-7

Dipartimento di Scienze Biomorfologiche e Funzionali, Università di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1002/mrd.20284DOI Listing
May 2005

Loss of the tumor suppressor gene PTEN marks the transition from intratubular germ cell neoplasias (ITGCN) to invasive germ cell tumors.

Oncogene 2005 Mar;24(11):1882-94

Dipartimento di Scienze Biomorfologiche e Funzionali, Facoltà di Medicina e Chirurgia, Università di Napoli Federico II, via S. Pansini, 5, 80131 Napoli, Italy.

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http://dx.doi.org/10.1038/sj.onc.1208368DOI Listing
March 2005

Aurora B overexpression associates with the thyroid carcinoma undifferentiated phenotype and is required for thyroid carcinoma cell proliferation.

J Clin Endocrinol Metab 2005 Feb 23;90(2):928-35. Epub 2004 Nov 23.

Dipartimento di Biologia e Patologia Cellulare e Molecolare, Università Federico II, via S. Pansini 5, 80131 Napoli, Italy.

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http://dx.doi.org/10.1210/jc.2004-1518DOI Listing
February 2005

Environmental influence on testicular MAP kinase (ERK1) activity in the frog Rana esculenta.

J Exp Biol 2004 Jun;207(Pt 13):2209-13

Dipartimento di Medicina Sperimentale, II Università di Napoli, Naples, Italy.

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http://dx.doi.org/10.1242/jeb.01000DOI Listing
June 2004

Phosphorylation of high-mobility group protein A2 by Nek2 kinase during the first meiotic division in mouse spermatocytes.

Mol Biol Cell 2004 Mar 10;15(3):1224-32. Epub 2003 Dec 10.

Dipartimento di Sanità Pubblica e Biologia Cellulare, University of Rome "Tor Vergata," 00133 Rome, Italy.

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http://dx.doi.org/10.1091/mbc.e03-09-0638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC363112PMC
March 2004

Estrogen receptor beta localization in the lizard (Podarcis s. sicula) testis.

Zygote 2004 Feb;12(1):39-42

Dipartimento di Medicina Sperimentale, II Università di Napoli, Naples, Italy.

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February 2004

Changes in JNK1 activity in the frog (Rana esculenta) testis.

Authors:
Paolo Chieffi

Mol Reprod Dev 2003 Dec;66(4):398-402

Dipartimento di Medicina Sperimentale, II Università di Napoli, Naples, Italy.

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http://dx.doi.org/10.1002/mrd.10363DOI Listing
December 2003

Translational regulation of a novel testis-specific RNF4 transcript.

Mol Reprod Dev 2003 Sep;66(1):1-7

Dipartimento di Biologia e Patologia Cellulare e Molecolare L. Califano, IEOS del C.N.R., Università di Napoli Federico II, Naples, Italy.

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http://dx.doi.org/10.1002/mrd.10322DOI Listing
September 2003

17beta-estradiol-induced activation of ERK1/2 through endogenous androgen receptor-estradiol receptor alpha-Src complex in human prostate cells.

Int J Oncol 2003 Sep;23(3):797-801

Dipartimento di Medicina Sperimentale, II Università di Napoli, Via Constantinopoli 16, I-80138 Naples, Italy.

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September 2003

Prolin-rich tyrosine kinase 2 (PYK2) expression and localization in mouse testis.

Mol Reprod Dev 2003 Jul;65(3):330-5

Dipartimento di Medicina Sperimentale, II Università di Napoli, Naples, Italy.

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http://doi.wiley.com/10.1002/mrd.10297
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http://dx.doi.org/10.1002/mrd.10297DOI Listing
July 2003

HMGA1 and HMGA2 protein expression in mouse spermatogenesis.

Oncogene 2002 May;21(22):3644-50

Dipartimento di Medicina Sperimentale, II Università di Napoli, via Costantinopoli 16, 80138 Naples, Italy.

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http://dx.doi.org/10.1038/sj.onc.1205501DOI Listing
May 2002

Proline-rich tyrosine kinase 2 regulates proliferation and differentiation of prostate cells.

Mol Cell Endocrinol 2002 Jan;186(1):81-7

Dipartimento di Biologia e Patologia Molecolare e Cellulare 'Luigi Califano', Centro di Endocrinologia ed Oncologia Sperimentale del CNR, Universita degli Studi di Napoli, 'Federico II' Via Pansini 5, 80131, Naples, Italy.

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http://dx.doi.org/10.1016/s0303-7207(01)00667-0DOI Listing
January 2002