Paolo Carai

Paolo Carai

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Paolo Carai

Paolo Carai

Publications by authors named "Paolo Carai"

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ADAMTS5 deficiency in mice does not affect cardiac function.

Cell Biol Int 2019 Jun 21;43(6):593-604. Epub 2019 Apr 21.

Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, KU Leuven, 3000 Leuven, Belgium.

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http://dx.doi.org/10.1002/cbin.11130DOI Listing
June 2019

AntagomiR-103 and -107 Treatment Affects Cardiac Function and Metabolism.

Mol Ther Nucleic Acids 2019 Mar 22;14:424-437. Epub 2018 Dec 22.

CARIM School for Cardiovascular Diseases, Department of Cardiology, Maastricht University, 6229 ER Maastricht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.omtn.2018.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365487PMC
March 2019

SPARC preserves endothelial glycocalyx integrity, and protects against adverse cardiac inflammation and injury during viral myocarditis.

Matrix Biol 2018 12 3;74:21-34. Epub 2018 May 3.

Center for Heart Failure Research, Cardiovascular Research Institute Maastricht, The Netherlands; Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU, Leuven, Belgium.

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https://linkinghub.elsevier.com/retrieve/pii/S0945053X183007
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http://dx.doi.org/10.1016/j.matbio.2018.04.015DOI Listing
December 2018

NF-κB-mediated metabolic remodelling in the inflamed heart in acute viral myocarditis.

Biochim Biophys Acta Mol Basis Dis 2018 Aug 3;1864(8):2579-2589. Epub 2018 May 3.

Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands; Department of Physiology, CARIM, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.bbadis.2018.04.022DOI Listing
August 2018

Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.

Matrix Biol 2018 03 25;66:110-124. Epub 2017 Sep 25.

Center for Heart Failure Research, Cardiovascular Research Institute Maastricht, The Netherlands; Molecular and Vascular Biology, Department of Cardiovascular Sciences, KU Leuven, Belgium; ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.matbio.2017.09.002DOI Listing
March 2018

Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.

Circulation 2017 Aug 13;136(8):747-761. Epub 2017 Jun 13.

From Center for Molecular and Vascular Research, Leuven, Belgium (W.H., A.P., S.D., Pa.C., P.P., A.S.W., S.J., S.H.); Center for Heart Failure Research, Department of Cardiology, CARIM School for Cardiovascular Diseases, Maastricht University, The Netherlands (W.H., A.P., S.D., Pa.C., W.V., R.v.L., B.S., M.v.B., S.H.); Cardiovascular Research Center, OLV Hospital, Aalst, Belgium (W.H.); Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Department of Oncology, Leuven, Belgium (A.Q., G.E., S.S., S.V., Pe.C.); Laboratory of Angiogenesis and Vascular Metabolism, Vesalius Research Center, Leuven, Belgium (A.Q., G.E., S.S., S.V., Pe.C.); Amsterdam Medical Center, Amsterdam University, The Netherlands (S.A., I.E., Y.P.); Laboratory for Viral Vector Technology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences (R.G., C.V.D.H.), Laboratory for Neurobiology and Gene Therapy, Department of Neurosciences (R.G., C.V.D.H.), Leuven Viral Vector Core, Belgium (R.G., C.V.D.H.); and Klinik für Innere Medezin III, Universitätsklinikum des Saarlandes, Homburg, Germany (A.N., C.M.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.024171DOI Listing
August 2017

Sema3A promotes the resolution of cardiac inflammation after myocardial infarction.

Basic Res Cardiol 2017 07 24;112(4):42. Epub 2017 May 24.

Cardiovascular Research Institute Maastricht, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00395-017-0630-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5443852PMC
July 2017

A novel 72-kDa leukocyte-derived osteoglycin enhances the activation of toll-like receptor 4 and exacerbates cardiac inflammation during viral myocarditis.

Cell Mol Life Sci 2017 04 23;74(8):1511-1525. Epub 2016 Nov 23.

Center for Heart Failure Research, Cardiovascular Research Institute Maastricht, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.

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http://dx.doi.org/10.1007/s00018-016-2423-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357299PMC
April 2017

Breeding Strategy Determines Rupture Incidence in Post-Infarct Healing WARPing Cardiovascular Research.

PLoS One 2015 25;10(9):e0139199. Epub 2015 Sep 25.

Department of Cardiology, Maastricht University, Maastricht, The Netherlands; Centre for Molecular and Vascular Biology, KULeuven, Leuven, Belgium.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0139199PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4583407PMC
June 2016

The microRNA-221/-222 cluster balances the antiviral and inflammatory response in viral myocarditis.

Eur Heart J 2015 11 22;36(42):2909-19. Epub 2015 Jul 22.

Center for Heart Failure Research, Cardiovascular Research Institute Maastricht, Maastricht University, P. Debyelaan 25, Maastricht AZ-6202, The Netherlands Center for Molecular and Vascular Research, University of Leuven, Leuven B-3000, Belgium

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http://eurheartj.oxfordjournals.org/content/ehj/36/42/2909.f
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http://eurheartj.oxfordjournals.org/lookup/doi/10.1093/eurhe
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http://dx.doi.org/10.1093/eurheartj/ehv321DOI Listing
November 2015

Liver X receptor activation enhances CVB3 viral replication during myocarditis by stimulating lipogenesis.

Cardiovasc Res 2015 Jul 21;107(1):78-88. Epub 2015 May 21.

Centre for Molecular and Vascular Biology (CMVB), Department of Cardiovascular Sciences, KU Leuven, Leuven, Belgium CArdiovascular Research Institute Maastricht (CARIM), Universiteitssingel 50, 6229 ER Maastricht, The Netherlands ICIN - Netherlands Heart Institute, Utrecht, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvv157DOI Listing
July 2015

Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening.

Circ Res 2015 Jan 17;116(3):425-36. Epub 2014 Dec 17.

From the Department of Cardiovascular Sciences, Center for Molecular and Vascular Biology, Catholic University of Leuven, Leuven, Belgium (L.N.L.V.A., P.C., A.-P.P., S.H.); Department of Cardiology (L.N.L.V.A., M.S.) and Department of Pathology (E.V.), University Hospitals Leuven, Leuven, Belgium; Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany (S.V., H.N., C.T., H.M.); Department of Cardiology, Cardiovascular Research Institute Maastricht (CARIM), University Hospital Maastricht, Maastricht, The Netherlands (P.C., R.V.L., S.S.-v.W., L.E., H.-P.B.-L.R., A.-P.P., S.H.); Department of Pediatrics, Molecular Cardiovascular Biology, Cincinnati Children's Hospital Medical Center, University of Cincinnati, OH (D.V.); Department of Molecular Cell Biology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands (F.K.V.); National Heart and Lung Institute, Cardiovascular Genetics and Genomics, London, United Kingdom (S.A.C.); National Heart Centre Singapore, Department of Cardiology, Singapore (S.A.C.); Duke-NUS Graduate Medical School, Singapore (S.A.C.); Department of Cardiology, University Hospital Basel, Basel, Switzerland (H.-P.B.-L.R.); and ICIN-Netherlands Heart Institute, Utrecht, The Netherlands (S.H.).

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http://dx.doi.org/10.1161/CIRCRESAHA.116.304599DOI Listing
January 2015

Lymphocytes infiltrate the quadriceps muscle in lymphocytic myocarditis patients: a potential new diagnostic tool.

Can J Cardiol 2014 Dec 22;30(12):1547-54. Epub 2014 Jul 22.

Department of Pathology, VU Medical Center, Amsterdam, The Netherlands; ICaR-VU, Institute of Cardiovascular Research, VU Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.cjca.2014.07.018DOI Listing
December 2014

Macrophage microRNA-155 promotes cardiac hypertrophy and failure.

Circulation 2013 Sep 16;128(13):1420-32. Epub 2013 Aug 16.

Center for Heart Failure Research, Department of Cardiology (S.H., M.F.C., W.V., P.C., R.E.W.v.L., K.C., T.P., M.H., M.v.B., A.-P.P., B.S.), Department of Molecular Genetics (L.S., M.P.J.d.W.), Department of Pathology (E.W., E.L.), Department of Pharmacology (B.J.J.), Department of Cardiology (L.J.d.W.), and Department of Internal Medicine (K.W.), Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, the Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands (S.H.); Center for Molecular and Cardiovascular Biology, Department of Cardiovascular Sciences, Leuven, Belgium (S.H., P.C., A.-P.P.); Department of Medical Biochemistry (L.S., E.L., M.P.J.d.W.) and Heart Failure Research Center (E.E.C., Y.M.P.), Academic Medical Center, Amsterdam, the Netherlands; Cluster of Excellence Cell Networks, Department of Infectious Diseases/Virology, Virus Host Interactions, Heidelberg University, Heidelberg, Germany (D.G., N.S.); Laboratory of Lymphocyte Signaling and Development, Babraham Institute, Cambridge, UK (E.V.); Institute for Molecular and Translational Therapeutic Strategies, Hannover Medical School, Hannover, Germany (T.T.); Medical Microbiology, Maastricht University, Maastricht, the Netherlands (F.S.); King's BHF Centre, King's College London, London UK (X.Y., M.M.); Institute for Cardiovascular Prevention, Ludwig Maximilians University, Munich, Germany (E.L.); and Molecular Medicine Laboratory, International Centre for Genetic Engineering and Biotechnology, Trieste, Italy (S.Z., M.G.).

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http://circ.ahajournals.org/content/early/2013/08/16/CIRCULA
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http://circ.ahajournals.org/cgi/doi/10.1161/CIRCULATIONAHA.1
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http://dx.doi.org/10.1161/CIRCULATIONAHA.112.001357DOI Listing
September 2013

Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy.

J Mol Cell Cardiol 2011 Sep 23;51(3):318-28. Epub 2011 May 23.

Center for Heart Failure Research, Cardiovascular Research Institute Maastricht, Maastricht University, PO Box 5800, 6202 AZ Maastricht, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2011.05.010DOI Listing
September 2011