Publications by authors named "Paola Rogliani"

100Publications

Mortality in ETHOS, a Question of "Power".

Am J Respir Crit Care Med 2021 Jan 14. Epub 2021 Jan 14.

Università degli Studi di Parma, 9370, Parma, Emilia-Romagna, Italy.

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January 2021

Pharmacokinetic/pharmacodynamic approaches to drug delivery design for inhalation drugs.

Expert Opin Drug Deliv 2021 Jan 19:1-16. Epub 2021 Jan 19.

Unit of Respiratory Medicine, Dept. Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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January 2021

Happy hypoxemia, or blunted ventilation?

Respir Res 2021 01 6;22(1). Epub 2021 Jan 6.

Respiratory Investigation Unit, Department of Medicine, Queen's University, Kingston, ON, Canada.

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January 2021

Persistence of both reversible airway obstruction and higher blood eosinophils may predict lung function decline in severe asthma.

Clin Respir J 2021 Jan 5. Epub 2021 Jan 5.

Department of Surgery, Medicine, Molecular Biology and Critical Care, University of Pisa, Pisa, Italy.

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January 2021

Reply to Han et al.: impact on mortality of triple ICS/LABA/LAMA therapy in a population of COPD patients including also subjects with asthma-like profile.

Expert Rev Respir Med 2020 Dec 28:1-3. Epub 2020 Dec 28.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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December 2020

Safety of N-Acetylcysteine at High Doses in Chronic Respiratory Diseases: A Review.

Drug Saf 2020 Dec 16. Epub 2020 Dec 16.

Section of Cardiorespiratory and Internal Medicine, Department of Medical Sciences, Research Centre on Asthma and COPD, University of Ferrara, Ferrara, Italy.

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December 2020

Long-Acting Muscarinic Antagonists Under Investigational to Treat Chronic Obstructive Pulmonary Disease.

J Exp Pharmacol 2020 8;12:559-574. Epub 2020 Dec 8.

Division of Respiratory Medicine, University Hospital Tor Vergata, Rome, Italy.

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December 2020

Prospects for severe asthma treatment.

Curr Opin Pharmacol 2020 Dec 10;56:52-60. Epub 2020 Dec 10.

Division of Respiratory Medicine, University Hospital "Tor Vergata", Rome, Italy; Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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December 2020

Guidance on nebulization during the current COVID-19 pandemic.

Respir Med 2020 Nov 19;176:106236. Epub 2020 Nov 19.

Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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November 2020

Reduced risk of COVID-19 hospitalization in asthmatic and COPD patients: a benefit of inhaled corticosteroids?

Expert Rev Respir Med 2020 Dec 3:1-8. Epub 2020 Dec 3.

Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma , Parma, Italy.

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December 2020

Efficacy and safety of triple combination therapy for treating chronic obstructive pulmonary disease: an expert review.

Expert Opin Pharmacother 2020 Nov 11:1-10. Epub 2020 Nov 11.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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November 2020

Are there pulmonary sequelae in patients recovering from COVID-19?

Respir Res 2020 Oct 30;21(1):286. Epub 2020 Oct 30.

Department of Surgical Sciences, Unit of Radiology, University of Rome "Tor Vergata", Rome, Italy.

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October 2020

Advances in understanding of mechanisms related to increased cardiovascular risk in COPD.

Expert Rev Respir Med 2021 Jan 4;15(1):59-70. Epub 2020 Nov 4.

Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma , Parma, Italy.

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January 2021

Multifaceted Beneficial Effects of Erdosteine: More than a Mucolytic Agent.

Drugs 2020 Nov;80(17):1799-1809

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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November 2020

Depressive and anxiety symptoms in patients with SARS-CoV2 infection.

J Affect Disord 2021 01 14;278:339-340. Epub 2020 Sep 14.

Neurology Unit, University Hospital "Tor Vergata", Rome, Italy; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; IRCCS Santa Lucia Foundation, Rome, Italy.

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January 2021

Experimental Glucocorticoid Receptor Agonists for the Treatment of Asthma: A Systematic Review.

J Exp Pharmacol 2020 6;12:233-254. Epub 2020 Aug 6.

Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy.

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August 2020

Optimizing de-escalation of inhaled corticosteroids in COPD: a systematic review of real-world findings.

Expert Rev Clin Pharmacol 2020 Sep 20;13(9):977-990. Epub 2020 Sep 20.

Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma , Parma, Italy.

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September 2020

Targeting IL-5 pathway against airway hyperresponsiveness: A comparison between benralizumab and mepolizumab.

Br J Pharmacol 2020 Oct 17;177(20):4750-4765. Epub 2020 Sep 17.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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October 2020

Evaluating triple ICS/LABA/LAMA therapies for COPD patients: a network meta-analysis of ETHOS, KRONOS, IMPACT, and TRILOGY studies.

Expert Rev Respir Med 2021 Jan 14;15(1):143-152. Epub 2020 Sep 14.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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January 2021

Sleep and wake impairment in patients with SARS-CoV2 infection.

Sleep Med 2020 09 17;73:177-178. Epub 2020 Jul 17.

Neurology Unit, University Hospital "Tor Vergata", Rome, Italy; Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.

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September 2020

Advances with glucocorticoids in the treatment of asthma: state of the art.

Expert Opin Pharmacother 2020 Dec 18;21(18):2305-2316. Epub 2020 Aug 18.

Division of Respiratory Medicine, University Hospital "Policlinico Tor Vergata" , Rome, Italy.

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December 2020

Pharmacogenomic Response of Inhaled Corticosteroids for the Treatment of Asthma: Considerations for Therapy.

Pharmgenomics Pers Med 2020 4;13:261-271. Epub 2020 Aug 4.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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August 2020

Pharmacological management of COVID-19 patients with ARDS (CARDS): A narrative review.

Respir Med 2020 09 4;171:106114. Epub 2020 Aug 4.

Unit of Respiratory Medicine, Dept. Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy. Electronic address:

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September 2020

Pharmacological management of adult patients with acute respiratory distress syndrome.

Expert Opin Pharmacother 2020 Dec 12;21(17):2169-2183. Epub 2020 Aug 12.

Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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December 2020

Dyspnea perception and neurological symptoms in non-severe COVID-19 patients.

Neurol Sci 2020 Oct 30;41(10):2671-2674. Epub 2020 Jul 30.

Respiratory Medicine Unit, University Hospital Policlinico Tor Vergata, Rome, Italy.

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October 2020

Day and Night Control of COPD and Role of Pharmacotherapy: A Review.

Int J Chron Obstruct Pulmon Dis 2020 4;15:1269-1285. Epub 2020 Jun 4.

Department of Biomedicine and Internal and Specialistic Medicine (DIBIMIS), University of Palermo, Palermo, Italy.

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June 2020

The latest on the role of LAMAs in asthma.

J Allergy Clin Immunol 2020 Dec 27;146(6):1288-1291. Epub 2020 Jun 27.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli," Naples, Italy.

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December 2020

The role of triple therapy in the management of COPD.

Expert Rev Clin Pharmacol 2020 Aug 13;13(8):865-874. Epub 2020 Jul 13.

Unit of Respiratory Medicine, Unit of Pharmacology, Department Experimental Medicine, Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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August 2020

Ergonomical Assessment of Three-Dimensional Versus Two-Dimensional Thoracoscopic Lobectomy.

Semin Thorac Cardiovasc Surg 2020 Winter;32(4):1089-1096. Epub 2020 May 23.

Department of Thoracic Surgery, Policlinico Tor Vergata University, Rome, Italy. Electronic address:

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May 2020

SMART and as-needed therapies in mild-to-severe asthma: a network meta-analysis.

Eur Respir J 2020 Sep 10;56(3). Epub 2020 Sep 10.

Unit of Respiratory Medicine, Dept of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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September 2020

Subjective neurological symptoms frequently occur in patients with SARS-CoV2 infection.

Brain Behav Immun 2020 08 19;88:11-16. Epub 2020 May 19.

Neurology Unit, University Hospital "Tor Vergata", Rome, Italy; Department of Systems Medicine, University of Rome "Tor Vergata", Rome, Italy; IRCCS Santa Lucia Foundation, Rome, Italy.

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August 2020

Investigational treatments in phase I and II clinical trials: a systematic review in chronic obstructive pulmonary disease (COPD).

Expert Opin Investig Drugs 2020 Jul 27;29(7):723-738. Epub 2020 May 27.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome, Italy.

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July 2020

Anxiety and depression in adolescents with asthma and in their parents. Is an increased basal cholinergic tone a possible further reason to explain the negative impact on asthma control?

Monaldi Arch Chest Dis 2020 Apr 8;90(1). Epub 2020 Apr 8.

Postgraduate School of Respiratory Medicine, Department of Experimental Medicine; Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata".

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April 2020

Evaluation of fluticasone propionate/salmeterol for the treatment of COPD: a systematic review.

Expert Rev Respir Med 2020 06 4;14(6):621-635. Epub 2020 Apr 4.

Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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June 2020

Advances in pulmonary drug delivery devices for the treatment of chronic obstructive pulmonary disease.

Expert Opin Drug Deliv 2020 05 16;17(5):635-646. Epub 2020 Mar 16.

Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata", Rome, Italy.

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May 2020

The possible concomitant use of aeroallergen and food panels for skin prick testing might enhance the risk of generalized allergic reactions in children.

Turk J Pediatr 2019 ;61(5):815-816

Department of Pulmonology, Haematology and Oncology Division of Pulmonology Unit of Allergology, High Speciality "A. Cardarelli" Hospital, Naples.

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May 2020

TSLP Inhibitors for Asthma: Current Status and Future Prospects.

Drugs 2020 Apr;80(5):449-458

Chair of Respiratory Medicine, Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.

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April 2020

α-Antitrypsin deficiency and chronic respiratory disorders.

Eur Respir Rev 2020 Mar 12;29(155). Epub 2020 Feb 12.

Unit of Pharmacology, Dept Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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March 2020

Severe Asthma and Biological Therapy: When, Which, and for Whom.

Pulm Ther 2020 Jun 26;6(1):47-66. Epub 2019 Dec 26.

Respiratory Unit, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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June 2020

Triple Therapy Versus Dual Bronchodilation and Inhaled Corticosteroids/Long-Acting β-Agonists in COPD: Accumulating Evidence from Network Meta-Analyses.

Pulm Ther 2019 Dec 2;5(2):117-126. Epub 2019 Nov 2.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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December 2019

Age does not affect the efficacy of anti-IL-5/IL-5R in severe asthmatics.

World Allergy Organ J 2019 Nov 6;12(11):100081. Epub 2019 Nov 6.

University of Palermo, Dipartimento Universitario di Promozione Salute, Materno Infantile, Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro" (PROMISE) c/o Pneumologia AOUP "Paolo Giaccone", Palermo, Italy.

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November 2019

A long-term clinical trial on the efficacy and safety profile of doxofylline in Asthma: The LESDA study.

Pulm Pharmacol Ther 2020 02 26;60:101883. Epub 2019 Dec 26.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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February 2020

The future of bronchodilation: looking for new classes of bronchodilators.

Eur Respir Rev 2019 Dec 23;28(154). Epub 2019 Dec 23.

Dept of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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December 2019

Satisfaction with chronic obstructive pulmonary disease treatment: results from a multicenter, observational study.

Ther Adv Respir Dis 2019 Jan-Dec;13:1753466619888128

Department of Biomedical and Clinical Sciences (DIBIC), Università di Milano, Division of Respiratory Diseases, 'L. Sacco' Hospital, Via G.B. Grassi 74, Milan 20157, Italy.

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June 2020

Beclomethasone dipropionate, formoterol fumarate and glycopyrronium bromide: Synergy of triple combination therapy on human airway smooth muscle ex vivo.

Br J Pharmacol 2020 03 29;177(5):1150-1163. Epub 2020 Jan 29.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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March 2020

Optimizing the Development Strategy of Combination Therapy in Respiratory Medicine: From Isolated Airways to Patients.

Adv Ther 2019 12 25;36(12):3291-3298. Epub 2019 Oct 25.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy.

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December 2019

The impact of comorbidities on severe asthma.

Curr Opin Pulm Med 2020 01;26(1):47-55

Department of Experimental Medicine, University of Rome 'Tor Vergata', Rome, Italy.

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January 2020

Impact of ICS/LABA and LABA/LAMA FDCs on functional and clinical outcomes in COPD: A network meta-analysis.

Pulm Pharmacol Ther 2019 12 19;59:101855. Epub 2019 Oct 19.

Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.

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December 2019

Pharmacological treatment and current controversies in COPD.

F1000Res 2019 29;8. Epub 2019 Aug 29.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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May 2020

Ensifentrine (RPL554): an investigational PDE3/4 inhibitor for the treatment of COPD.

Expert Opin Investig Drugs 2019 Oct 1;28(10):827-833. Epub 2019 Sep 1.

Unit of Pharmacology, Dept. Experimental Medicine, University of Campania "Luigi Vanvitelli" , Naples , Italy.

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October 2019

Ultra-LABAs for the treatment of asthma.

Respir Med 2019 09 12;156:47-52. Epub 2019 Aug 12.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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September 2019

A potential role of triple therapy for asthma patients.

Expert Rev Respir Med 2019 11 1;13(11):1079-1085. Epub 2019 Sep 1.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata" , Rome , Italy.

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November 2019

Sensitization to Cat: Why Not Use Molecular Diagnostics instead of the Nasal Challenge in Clinical Practice?

Int Arch Allergy Immunol 2019 14;180(2):142-143. Epub 2019 Aug 14.

Department of Experimental Medicine, Postgraduate School of Respiratory Medicine, University of Rome "Tor Vergata", Rome, Italy.

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October 2019

Efficacy and safety profile of doxofylline compared to theophylline in asthma: a meta-analysis.

Multidiscip Respir Med 2019 3;14:25. Epub 2019 Aug 3.

3Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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August 2019

Evolving Concepts in Chronic Obstructive Pulmonary Disease Blood-Based Biomarkers.

Mol Diagn Ther 2019 10;23(5):603-614

Department of Experimental Medicine, University of Rome Tor Vergata, Rome, Italy.

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October 2019

Pharmacokinetics and pharmacodynamics of inhaled corticosteroids for asthma treatment.

Pulm Pharmacol Ther 2019 10 23;58:101828. Epub 2019 Jul 23.

University of Rome "Tor Vergata", Department of Experimental Medicine, Rome, Italy. Electronic address:

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October 2019

Thiol-Based Drugs in Pulmonary Medicine: Much More than Mucolytics.

Trends Pharmacol Sci 2019 07 27;40(7):452-463. Epub 2019 May 27.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.

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July 2019

Monoclonal antibodies for severe asthma: Pharmacokinetic profiles.

Respir Med 2019 07 13;153:3-13. Epub 2019 May 13.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy. Electronic address:

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July 2019

Efficacy and safety profile of mucolytic/antioxidant agents in chronic obstructive pulmonary disease: a comparative analysis across erdosteine, carbocysteine, and N-acetylcysteine.

Respir Res 2019 May 27;20(1):104. Epub 2019 May 27.

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Via Montpellier 1, 00133, Rome, Italy.

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May 2019

Monoclonal antibodies in severe asthma: is it worth it?

Expert Opin Drug Metab Toxicol 2019 Jun 23;15(6):517-520. Epub 2019 May 23.

a Unit of Respiratory Medicine, Department of Experimental Medicine , University of Rome "Tor Vergata" , Rome , Italy.

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June 2019

Response.

Chest 2019 05;155(5):1079-1080

Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata", Rome, Italy.

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May 2019

Bronchodilators in subjects with asthma-related comorbidities.

Respir Med 2019 05 3;151:43-48. Epub 2019 Apr 3.

Chair of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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May 2019

Cardiovascular Disease in Chronic Respiratory Disorders and Beyond.

J Am Coll Cardiol 2019 05;73(17):2178-2180

Unit of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata," Rome, Italy.

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May 2019

Pharmacological characterization of the interaction between tiotropium bromide and olodaterol on human bronchi and small airways.

Pulm Pharmacol Ther 2019 06 12;56:39-50. Epub 2019 Mar 12.

Unit of Pharmacology, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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June 2019

Can f 5 as a suitable marker of dog allergy: Assess male dog exposure before banning it.

J Allergy Clin Immunol 2019 04 10;143(4):1657-1658. Epub 2019 Feb 10.

Postgraduate School of Respiratory Medicine, Department of Experimental Medicine, University of Rome "Tor Vergata", Rome, Italy; Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata", Rome, Italy.

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April 2019

Inhaled therapies and cardiovascular risk in patients with chronic obstructive pulmonary disease.

Expert Opin Pharmacother 2019 04 1;20(6):737-750. Epub 2019 Feb 1.

b Division of Respiratory Medicine , University Hospital "Tor Vergata" , Rome , Italy.

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April 2019

Adding a LAMA to ICS/LABA Therapy: A Meta-analysis of Triple Combination Therapy in COPD.

Chest 2019 04 17;155(4):758-770. Epub 2019 Jan 17.

Department of Experimental Medicine, Unit of Respiratory Medicine, University of Rome "Tor Vergata," Rome, Italy.

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April 2019

Disease awareness in patients with COPD: measurement and extent.

Int J Chron Obstruct Pulmon Dis 2019;14:1-11. Epub 2018 Dec 17.

Department of Internal Medicine, Respiratory Diseases and Allergy Clinic, University of Genova, Azienda Policlinico IRCCS San Martino, Genoa, Italy.

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July 2019

Current pharmacotherapeutic options for pediatric lower respiratory tract infections with a focus on antimicrobial agents.

Expert Opin Pharmacother 2018 Dec 25;19(18):2043-2053. Epub 2018 Oct 25.

b Department of Experimental Medicine and Surgery , University of Rome Tor Vergata , Rome , Italy.

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December 2018

LABA/LAMA fixed-dose combinations in patients with COPD: a systematic review.

Int J Chron Obstruct Pulmon Dis 2018;13:3115-3130. Epub 2018 Oct 4.

Department of Health Sciences, Università degli Studi di Milano, Respiratory Unit, Papa Giovanni XXIII Hospital, Bergamo, Italy.

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March 2019

Triple therapy single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis.

Eur Respir J 2018 12 13;52(6). Epub 2018 Dec 13.

Unit of Pharmacology, Dept of Experimental Medicine, University of Campania "Luigi Vanvitelli", Naples, Italy.

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December 2018

Occupational exposure to furry animals and asthma: The complex interconnection between work and everyday life.

Ann Allergy Asthma Immunol 2018 10;121(4):512-513

Postgraduate School of Respiratory Medicine, Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy; Department of Experimental Medicine and Surgery, University of Rome "Tor Vergata", Rome, Italy.

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October 2018

Pharmacokinetic considerations concerning the use of bronchodilators in the treatment of chronic obstructive pulmonary disease.

Expert Opin Drug Metab Toxicol 2018 Oct 9;14(10):1101-1111. Epub 2018 Oct 9.

c Department of Experimental Medicine and Surgery , University of Rome Tor Vergata , Rome , Italy.

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October 2018