Publications by authors named "Paola Ricciardi-Castagnoli"

85Publications

Sensing the gut microbiota.

Nat Immunol 2020 07;21(7):704-705

Toscana Life Science Foundation, Siena, Italy.

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http://dx.doi.org/10.1038/s41590-020-0645-1DOI Listing
July 2020

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages.

J Immunol 2016 10 22;197(7):2838-53. Epub 2016 Aug 22.

Laboratory of Immunoregulation and Infection, The Francis Crick Institute, Mill Hill Laboratory, London NW7 1AA, United Kingdom; Department of Medicine, National Heart and Lung Institute, Imperial College London, London SW3 6LY, United Kingdom

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http://dx.doi.org/10.4049/jimmunol.1501923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5026030PMC
October 2016

PD-1 expression on dendritic cells suppresses CD8 T cell function and antitumor immunity.

Oncoimmunology 2016 Mar 31;5(3):e1085146. Epub 2015 Aug 31.

Genomics, Genetics and Biology Innovation Pole (PoloGGB), Piazza Gambuli, Edificio D, 3° Piano, Perugia, Italy; A. Menarini Biomarkers Singapore Pte Ltd, 30 Pasir Panjang Road, #08-32, Mapletree Business City, Singapore.

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http://dx.doi.org/10.1080/2162402X.2015.1085146DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839350PMC
March 2016

CD103(+) Dendritic Cells Control Th17 Cell Function in the Lung.

Cell Rep 2015 Sep 10;12(11):1789-801. Epub 2015 Sep 10.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.030DOI Listing
September 2015

Dendritic cell derived IL-2 inhibits survival of terminally mature cells via an autocrine signaling pathway.

Eur J Immunol 2015 May 18;45(5):1494-9. Epub 2015 Mar 18.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1002/eji.201445050DOI Listing
May 2015

MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b.

J Immunol 2015 Mar 30;194(5):2079-88. Epub 2015 Jan 30.

Division of Rheumatology, Immunology and Allergy, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

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http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1401072
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http://dx.doi.org/10.4049/jimmunol.1401072DOI Listing
March 2015

NFATc2 mediates epigenetic modification of dendritic cell cytokine and chemokine responses to dectin-1 stimulation.

Nucleic Acids Res 2015 Jan 30;43(2):836-47. Epub 2014 Dec 30.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*Star), Biopolis, Singapore

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http://dx.doi.org/10.1093/nar/gku1369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333412PMC
January 2015

Phagocytosis of Particulate Antigens - All Roads Lead to Calcineurin/NFAT Signaling Pathway.

Front Immunol 2014 Jan 9;4:513. Epub 2014 Jan 9.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (ASTAR) , Biopolis , Singapore.

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http://dx.doi.org/10.3389/fimmu.2013.00513DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885923PMC
January 2014

The NLRP3 inflammasome affects DNA damage responses after oxidative and genotoxic stress in dendritic cells.

Eur J Immunol 2013 Aug 24;43(8):2126-37. Epub 2013 May 24.

Singapore Immunology Network, Agency for Science, Technology and Research, A*STAR, Biopolis, Singapore.

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http://dx.doi.org/10.1002/eji.201242918DOI Listing
August 2013

The yin-yang nature of CSF1R-binding cytokines.

Nat Immunol 2012 Jul 19;13(8):717-9. Epub 2012 Jul 19.

Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Singapore.

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http://dx.doi.org/10.1038/ni.2375DOI Listing
July 2012

AMDA 2.13: A major update for automated cross-platform microarray data analysis.

Biotechniques 2012 Jul;53(1):33-40

Genopolis-Consortium for Functional Genomics, Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.2144/0000113889DOI Listing
July 2012

Interleukin-2 production by dendritic cells and its immuno-regulatory functions.

Front Immunol 2012 18;3:161. Epub 2012 Jun 18.

Singapore Immunology Network, Agency for Science, Technology and Research Singapore.

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http://dx.doi.org/10.3389/fimmu.2012.00161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376408PMC
August 2012

NFAT control of innate immunity.

Blood 2012 Aug 18;120(7):1380-9. Epub 2012 May 18.

Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Biopolis, Singapore.

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http://dx.doi.org/10.1182/blood-2012-02-404475DOI Listing
August 2012

Preface: Human immunology at SIgN.

Immunol Res 2012 Sep;53(1-3)

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #04 Immunos, Biopolis, Singapore.

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http://dx.doi.org/10.1007/s12026-012-8326-2DOI Listing
September 2012

Single-cell force spectroscopy: mechanical insights into the functional impacts of interactions between antigen-presenting cells and T cells.

Immunol Res 2012 Sep;53(1-3):108-14

Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #04 Immunos, Biopolis, Singapore.

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http://dx.doi.org/10.1007/s12026-012-8290-xDOI Listing
September 2012

The rhapsody of NLRPs: master players of inflammation...and a lot more.

Immunol Res 2012 Sep;53(1-3):78-90

Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, #04 Immunos, Biopolis, Singapore.

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http://dx.doi.org/10.1007/s12026-012-8272-zDOI Listing
September 2012

Calcineurin/NFAT signalling inhibits myeloid haematopoiesis.

EMBO Mol Med 2012 Apr 7;4(4):269-82. Epub 2012 Feb 7.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1002/emmm.201100207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376854PMC
April 2012

Uric acid-driven Th17 differentiation requires inflammasome-derived IL-1 and IL-18.

J Immunol 2011 Dec 4;187(11):5842-50. Epub 2011 Nov 4.

Singapore Immunology Network, Agency for Science, Technology, and Research, Biopolis 138648, Singapore.

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http://dx.doi.org/10.4049/jimmunol.1101408DOI Listing
December 2011

Classification of dendritic cell phenotypes from gene expression data.

BMC Immunol 2011 Aug 29;12:50. Epub 2011 Aug 29.

Genopolis Consortium, University of Milano-Bicocca, Milan, 20126, Italy.

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http://dx.doi.org/10.1186/1471-2172-12-50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3179938PMC
August 2011

Mechanical interactions between dendritic cells and T cells correlate with T cell responsiveness.

J Immunol 2011 Jul 27;187(1):258-65. Epub 2011 May 27.

Singapore Immunology Network, Agency for Science, Technology and Research, 138648 Singapore.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1100267
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http://dx.doi.org/10.4049/jimmunol.1100267DOI Listing
July 2011

From vaccine practice to vaccine science: the contribution of human immunology to the prevention of infectious disease.

Immunol Cell Biol 2011 Mar 8;89(3):332-9. Epub 2011 Feb 8.

Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Singapore.

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http://doi.wiley.com/10.1038/icb.2010.152
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http://dx.doi.org/10.1038/icb.2010.152DOI Listing
March 2011

The inflammasomes in health and disease: from genetics to molecular mechanisms of autoinflammation and beyond.

Cell Mol Immunol 2011 Mar 24;8(2):135-45. Epub 2011 Jan 24.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Immunos, Singapore.

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http://dx.doi.org/10.1038/cmi.2010.81DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4003142PMC
March 2011

Synergism of NOD2 and NLRP3 activators promotes a unique transcriptional profile in murine dendritic cells.

J Leukoc Biol 2010 Dec 30;88(6):1207-16. Epub 2010 Sep 30.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore.

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http://dx.doi.org/10.1189/jlb.1009652DOI Listing
December 2010

The controversial relationship between NLRP3, alum, danger signals and the next-generation adjuvants.

Eur J Immunol 2010 Mar;40(3):638-42

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A STAR), Singapore.

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http://doi.wiley.com/10.1002/eji.200940039
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http://dx.doi.org/10.1002/eji.200940039DOI Listing
March 2010

Gene expression profiles identify inflammatory signatures in dendritic cells.

PLoS One 2010 Feb 24;5(2):e9404. Epub 2010 Feb 24.

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0009404PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2827557PMC
February 2010

Temporal gene expression profile of the hippocampus following trace fear conditioning.

Brain Res 2010 Jan 24;1308:14-23. Epub 2009 Oct 24.

Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1016/j.brainres.2009.10.049DOI Listing
January 2010

The need to identify myeloid dendritic cell progenitors in human blood.

Trends Immunol 2010 Jan 14;31(1):18-23. Epub 2009 Oct 14.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Immunos #04-00, 8A Biomedical Grove, Singapore.

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http://dx.doi.org/10.1016/j.it.2009.09.010DOI Listing
January 2010

TPL-2 negatively regulates interferon-beta production in macrophages and myeloid dendritic cells.

J Exp Med 2009 Aug 10;206(9):1863-71. Epub 2009 Aug 10.

Division of Immunoregulation, Medical Research Council National Institute for Medical Research, Mill Hill, London NW7 1AA, UK.

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http://dx.doi.org/10.1084/jem.20091059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737152PMC
August 2009

How do human cells react to the absence of mitochondrial DNA?

PLoS One 2009 May 28;4(5):e5713. Epub 2009 May 28.

Unit of Molecular Neurogenetics-Pierfranco and Luisa Mariani Center for the study of Mitochondrial Disorders in Children, IRCCS Foundation Neurological Institute C. Besta, Milan, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005713PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2683933PMC
May 2009

Generation of murine growth factor-dependent long-term dendritic cell lines to investigate host-parasite interactions.

Methods Mol Biol 2009 ;531:17-27

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore.

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http://dx.doi.org/10.1007/978-1-59745-396-7_2DOI Listing
May 2009

Dendritic cells as sensors of environmental perturbations.

Microbes Infect 2008 Jul 10;10(9):990-4. Epub 2008 Jul 10.

Singapore Immunology Network , Singapore.

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http://dx.doi.org/10.1016/j.micinf.2008.07.013DOI Listing
July 2008

Statistical similarities between transcriptomics and quantitative shotgun proteomics data.

Mol Cell Proteomics 2008 Apr 19;7(4):631-44. Epub 2007 Nov 19.

Stowers Institute for Medical Research, Kansas City, Missouri 64110, USA.

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http://dx.doi.org/10.1074/mcp.M700240-MCP200DOI Listing
April 2008

Gene expression profiling of dendritic cells by microarray.

Methods Mol Biol 2007 ;380:215-24

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1007/978-1-59745-395-0_13DOI Listing
April 2008

Shaping immunity in healthy and diseased tissues.

Eur J Immunol 2007 Aug;37(8):2055-8

University of Milano-Bicocca, Department of Biotechnology, Piazza della Scienza 2, Milano, Italy.

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http://dx.doi.org/10.1002/eji.200790031DOI Listing
August 2007

Self-tolerance, dendritic cell (DC)-mediated activation and tissue distribution of natural killer (NK) cells.

Immunol Lett 2007 May 3;110(1):6-17. Epub 2007 Apr 3.

University of Milano-Bicocca, Department of Biotechnology and Bioscience, P.zza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1016/j.imlet.2007.03.001DOI Listing
May 2007

The genopolis microarray database.

BMC Bioinformatics 2007 Mar 8;8 Suppl 1:S21. Epub 2007 Mar 8.

Department Informatics, Systemistics and Communication, University of Milano-Bicocca, Via degli Arcimboldi 8, Milano, Italy.

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http://dx.doi.org/10.1186/1471-2105-8-S1-S21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1885851PMC
March 2007

Generation of gut-homing IgA-secreting B cells by intestinal dendritic cells.

Science 2006 Nov;314(5802):1157-60

CBR Institute for Biomedical Research and Department of Pathology, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1126/science.1132742DOI Listing
November 2006

AMDA: an R package for the automated microarray data analysis.

BMC Bioinformatics 2006 Jul 6;7:335. Epub 2006 Jul 6.

Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1186/1471-2105-7-335DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1534071PMC
July 2006

Dendritic cells in pathogen recognition and induction of immune responses: a functional genomics approach.

J Leukoc Biol 2006 May;79(5):913-6

Department of Biotechnology and bioscience, University of Milano-Bicocca, Milano, Italy.

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http://dx.doi.org/10.1189/jlb.1005547DOI Listing
May 2006

Induction of peripheral T cell tolerance by antigen-presenting B cells. I. Relevance of antigen presentation persistence.

J Immunol 2006 Apr;176(7):4012-20

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Italy.

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http://dx.doi.org/10.4049/jimmunol.176.7.4012DOI Listing
April 2006

Dendritic cell biology.

Adv Immunol 2005 ;88:193-233

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1016/S0065-2776(05)88006-XDOI Listing
December 2009

Antigen sampling by mucosal dendritic cells.

Trends Mol Med 2005 Sep;11(9):394-6

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, Milan, Italy.

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http://dx.doi.org/10.1016/j.molmed.2005.07.001DOI Listing
September 2005

TLR-dependent activation stimuli associated with Th1 responses confer NK cell stimulatory capacity to mouse dendritic cells.

J Immunol 2005 Jul;175(1):286-92

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.4049/jimmunol.175.1.286DOI Listing
July 2005

Genomic signatures of immune and inflammatory responses.

J Pediatr Gastroenterol Nutr 2005 Apr;40 Suppl 1:S45-6

University of Milan-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1097/00005176-200504001-00028DOI Listing
April 2005

A power law global error model for the identification of differentially expressed genes in microarray data.

BMC Bioinformatics 2004 Dec 17;5:203. Epub 2004 Dec 17.

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1186/1471-2105-5-203DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC545082PMC
December 2004

A central role for tissue-resident dendritic cells in innate responses.

Trends Immunol 2004 Dec;25(12):650-4

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, 20126 Milan, Italy.

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http://dx.doi.org/10.1016/j.it.2004.10.007DOI Listing
December 2004

A novel checkpoint in the Bcl-2-regulated apoptotic pathway revealed by murine cytomegalovirus infection of dendritic cells.

J Cell Biol 2004 Sep 7;166(6):827-37. Epub 2004 Sep 7.

Immunology and Virology Program, Centre for Ophthalmology and Visual Science, The University of Western Australia, Western Australia 6009, Australia.

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http://dx.doi.org/10.1083/jcb.200403010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2172116PMC
September 2004

Dendritic cell-derived IL-2 production is regulated by IL-15 in humans and in mice.

Blood 2005 Jan 7;105(2):697-702. Epub 2004 Sep 7.

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2004-03-1059DOI Listing
January 2005

The regulatory role of dendritic cells in the immune response.

Int Arch Allergy Immunol 2004 Jul 1;134(3):179-85. Epub 2004 Jun 1.

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milano, Italy.

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http://dx.doi.org/10.1159/000078764DOI Listing
July 2004

A type I IFN-dependent pathway induced by Schistosoma mansoni eggs in mouse myeloid dendritic cells generates an inflammatory signature.

J Immunol 2004 Mar;172(5):3011-7

Centre d'Immunologie et de Biologie Parasitaire, Institut National de la Santé et de la Recherche Médicale, Unité 547, Institut Pasteur de Lille, Lille, France.

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http://dx.doi.org/10.4049/jimmunol.172.5.3011DOI Listing
March 2004

The scavenger receptor MARCO mediates cytoskeleton rearrangements in dendritic cells and microglia.

Blood 2003 Oct 3;102(8):2940-7. Epub 2003 Jul 3.

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2002-12-3651DOI Listing
October 2003

The immune response is initiated by dendritic cells via interaction with microorganisms and interleukin-2 production.

J Infect Dis 2003 Jun;187 Suppl 2:S346-50

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

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http://dx.doi.org/10.1086/374748DOI Listing
June 2003

Early IL-2 production by mouse dendritic cells is the result of microbial-induced priming.

J Immunol 2003 May;170(10):5075-81

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Milan, Italy.

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http://www.jimmunol.org/content/170/10/5075.full.pdf
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http://dx.doi.org/10.4049/jimmunol.170.10.5075DOI Listing
May 2003

Interactions of bacterial pathogens with dendritic cells during invasion of mucosal surfaces.

Curr Opin Microbiol 2003 Feb;6(1):72-6

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza, 2-20126-Milano, Italy.

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http://dx.doi.org/10.1016/s1369-5274(03)00007-9DOI Listing
February 2003

Opinion: Interpretation of the complexity of innate immune responses by functional genomics.

Nat Rev Immunol 2002 Nov;2(11):881-9

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, Milan, Italy.

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http://dx.doi.org/10.1038/nri936DOI Listing
November 2002

Toll-like receptor 4 is not required for the full maturation of dendritic cells or for the degradation of Gram-negative bacteria.

Eur J Immunol 2002 Oct;32(10):2800-6

Department of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, I-20126 Milan, Italy.

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http://dx.doi.org/10.1002/1521-4141(2002010)32:10<2800::AID-IMMU2800>3.0.CO;2-5DOI Listing
October 2002

Granulocyte-macrophage colony-stimulating factor induces an expression program in neonatal microglia that primes them for antigen presentation.

J Immunol 2002 Sep;169(5):2264-73

Department of Cancer Immunology and AIDS, Dana-Farber Cancer Institute, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.4049/jimmunol.169.5.2264DOI Listing
September 2002

IL-2 mediates adjuvant effect of dendritic cells.

Trends Immunol 2002 Apr;23(4):169-71

Dept of Biotechnology and Bioscience, University of Milano-Bicocca, Piazza della Scienza 2, Milan, Italy.

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http://dx.doi.org/10.1016/s1471-4906(02)02187-7DOI Listing
April 2002

Langerhans cells: still a fundamental paradigm for studying the immunobiology of dendritic cells.

Trends Immunol 2002 Jan;23(1):6-8

Laboratory of Immunology, Istituto Dermopatico dell'Immacolata, IRCCS, I-00167, Rome, Italy.

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http://dx.doi.org/10.1016/s1471-4906(01)02125-1DOI Listing
January 2002