Paola Marighetti

Lung Cancer Onset in Wild Type Mice Following Bone Marrow Reconstitution with kras(v12) Cells.

Authors:

Elena Belloni Ines Martin Padura Elvira Gerbino Stefania Orecchioni Fulvia Fusar Imperatore Paola Marighetti Giovanni Bertalot Pier Giuseppe Pelicci Francesco Bertolini

Sci Rep 2015 Aug 12;5:13047. Epub 2015 Aug 12.

European Institute of Oncology, Laboratory of Hematology-Oncology, Milan, Italy.

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August 2015

The CDC42-interacting protein 4 controls epithelial cell cohesion and tumor dissemination.

Authors:

Yannève Rolland Paola Marighetti Chiara Malinverno Stefano Confalonieri Chiara Luise Nadia Ducano Andrea Palamidessi Sara Bisi Hiroaki Kajiho Flavia Troglio Olga G Shcherbakova Alexander R Dunn Amanda Oldani Letizia Lanzetti Pier Paolo Di Fiore Andrea Disanza Giorgio Scita

Dev Cell 2014 Sep;30(5):553-68

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Via Adamello 16, 20139 Milan, Italy; Dipartimento di Scienze della Salute, San Paolo, Università degli Studi di Milano, 20122 Milan, Italy. Electronic address:

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September 2014

A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination.

Authors:

Emanuela Frittoli Andrea Palamidessi Paola Marighetti Stefano Confalonieri Fabrizio Bianchi Chiara Malinverno Giovanni Mazzarol Giuseppe Viale Ines Martin-Padura Massimilliano Garré Dario Parazzoli Valentina Mattei Salvatore Cortellino Giovanni Bertalot Pier Paolo Di Fiore Giorgio Scita

J Cell Biol 2014 Jul;206(2):307-28

Fondazione Istituto FIRC di Oncologia Molecolare (IFOM), 20139 Milan, Italy Dipartimento di Scienze della Salute, Università degli Studi di Milano, 20122 Milan, Italy

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July 2014

CDC42 switches IRSp53 from inhibition of actin growth to elongation by clustering of VASP.

Authors:

Andrea Disanza Sara Bisi Moritz Winterhoff Francesca Milanesi Dmitry S Ushakov David Kast Paola Marighetti Guillaume Romet-Lemonne Hans-Michael Müller Walter Nickel Joern Linkner Davy Waterschoot Christophe Ampè Salvatore Cortellino Andrea Palamidessi Roberto Dominguez Marie-France Carlier Jan Faix Giorgio Scita

EMBO J 2013 Oct 27;32(20):2735-50. Epub 2013 Sep 27.

IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy.

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October 2013

Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer.

Authors:

Stefania Orecchioni Giuliana Gregato Ines Martin-Padura Francesca Reggiani Paola Braidotti Patrizia Mancuso Angelica Calleri Jessica Quarna Paola Marighetti Chiara Aldeni Giancarlo Pruneri Stefano Martella Andrea Manconi Jean-Yves Petit Mario Rietjens Francesco Bertolini

Cancer Res 2013 Oct 5;73(19):5880-91. Epub 2013 Aug 5.

Authors' Affiliations: Laboratory of Hematology-Oncology, Department of Pathology, and Division of Plastic Surgery, European Institute of Oncology; and Division of Pathology, San Paolo University Hospital, Milan, Italy.

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October 2013

Human haemato-endothelial precursors: cord blood CD34+ cells produce haemogenic endothelium.

Authors:

Elvira Pelosi Germana Castelli Ines Martin-Padura Veronica Bordoni Simona Santoro Alice Conigliaro Anna Maria Cerio Marco De Santis Puzzonia Paola Marighetti Mauro Biffoni Tonino Alonzi Laura Amicone Myriam Alcalay Francesco Bertolini Ugo Testa Marco Tripodi

PLoS One 2012 4;7(12):e51109. Epub 2012 Dec 4.

Department of Haematology, Oncology and Molecular Medicine, Istituto Superiore di Sanità, Rome, Italy.

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May 2013

Spontaneous cell fusion of acute leukemia cells and macrophages observed in cells with leukemic potential.

Authors:

Ines Martin-Padura Paola Marighetti Giuliana Gregato Alice Agliano Omar Malazzi Patrizia Mancuso Giancarlo Pruneri Andrea Viale Francesco Bertolini

Neoplasia 2012 Nov;14(11):1057-66

Laboratory of Hematology-Oncology, European Institute of Oncology, Milan, Italy.

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November 2012

Residual dormant cancer stem-cell foci are responsible for tumor relapse after antiangiogenic metronomic therapy in hepatocellular carcinoma xenografts.

Authors:

Ines Martin-Padura Paola Marighetti Alice Agliano Federico Colombo Leyre Larzabal Miriam Redrado Anne-Marie Bleau Celia Prior Francesco Bertolini Alfonso Calvo

Lab Invest 2012 Jul 30;92(7):952-66. Epub 2012 Apr 30.

Laboratory of Hematology-Oncology, European Institute of Oncology, Milan, Italy.

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July 2012

The white adipose tissue used in lipotransfer procedures is a rich reservoir of CD34+ progenitors able to promote cancer progression.

Authors:

Ines Martin-Padura Giuliana Gregato Paola Marighetti Patrizia Mancuso Angelica Calleri Chiara Corsini Giancarlo Pruneri Michela Manzotti Visnu Lohsiriwat Mario Rietjens Jean-Yves Petit Francesco Bertolini

Cancer Res 2012 Jan 3;72(1):325-34. Epub 2011 Nov 3.

Laboratory of Hematology-Oncology, European Institute of Oncology, Milan, Italy.

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January 2012

Anti-VEGF and beyond: shaping a new generation of anti-angiogenic therapies for cancer.

Authors:

Francesco Bertolini Paola Marighetti Ines Martin-Padura Patrizia Mancuso Dana D Hu-Lowe Yuval Shaked Alberto D'Onofrio

Drug Discov Today 2011 Dec 22;16(23-24):1052-60. Epub 2011 Aug 22.

Laboratory of Hematology-Oncology and Department of Experimental Oncology, European Institute of Oncology, 20141 Milan, Italy.

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December 2011

Therapeutic effect of lenalidomide in a novel xenograft mouse model of human blastic NK cell lymphoma/blastic plasmacytoid dendritic cell neoplasm.

Authors:

Alice Agliano Ines Martin-Padura Paola Marighetti Giuliana Gregato Angelica Calleri Celia Prior Miriam Redrado Alfonso Calvo Francesco Bertolini

Clin Cancer Res 2011 Oct 19;17(19):6163-73. Epub 2011 Aug 19.

Laboratory of Hematology-Oncology, European Institute of Oncology, Milan, Italy.

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October 2011

Evidence of distinct tumour-propagating cell populations with different properties in primary human hepatocellular carcinoma.

Authors:

Federico Colombo Francesca Baldan Silvia Mazzucchelli Ines Martin-Padura Paola Marighetti Alessandra Cattaneo Barbara Foglieni Marta Spreafico Silvana Guerneri Marco Baccarin Francesco Bertolini Giorgio Rossi Vincenzo Mazzaferro Massimiliano Cadamuro Marco Maggioni Luca Agnelli Paolo Rebulla Daniele Prati Laura Porretti

PLoS One 2011 23;6(6):e21369. Epub 2011 Jun 23.

Experimental Hepatology Laboratory, Centre of Transfusion Medicine, Cellular Therapy and Cryobiology, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

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November 2011