Pamela R Seida

Pamela R Seida

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Pamela R Seida

Pamela R Seida

Publications by authors named "Pamela R Seida"

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Nascent structure-activity relationship study of a diastereomeric series of kappa opioid receptor antagonists derived from CJ-15,208.

Bioorg Med Chem Lett 2009 Jul 3;19(13):3647-50. Epub 2009 May 3.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2009.04.105DOI Listing
July 2009

Discovery of a series of aminopiperidines as novel iNOS inhibitors.

Bioorg Med Chem Lett 2008 Jan 25;18(1):336-43. Epub 2007 Oct 25.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2007.10.073DOI Listing
January 2008

Synthesis and pharmacological evaluation of novel octahydro-1H-pyrido[1,2-a]pyrazine as mu-opioid receptor antagonists.

J Med Chem 2006 Dec;49(25):7290-306

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

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http://dx.doi.org/10.1021/jm0604878DOI Listing
December 2006

An ab initio molecular orbital study of the reduction of carbonyls by alkylaluminum complexes.

J Mol Graph Model 2005 Dec 26;24(3):195-202. Epub 2005 Aug 26.

Department of Chemistry, Eastern University, St. Davids, PA 19087, USA.

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http://dx.doi.org/10.1016/j.jmgm.2005.06.005DOI Listing
December 2005

Solid/solution-phase annulation reagents: single-step synthesis of cyclic amine derivatives.

Angew Chem Int Ed Engl 2005 Sep;44(36):5830-3

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1002/anie.200501665DOI Listing
September 2005

Azepinone as a conformational constraint in the design of kappa-opioid receptor agonists.

Bioorg Med Chem Lett 2004 Nov;14(22):5693-7

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

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http://dx.doi.org/10.1016/j.bmcl.2004.08.041DOI Listing
November 2004