Pamela Fischer-Posovszky

Pamela Fischer-Posovszky

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Pamela Fischer-Posovszky

Pamela Fischer-Posovszky

Publications by authors named "Pamela Fischer-Posovszky"

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Induction of apoptosis in ovarian cancer cells by miR-493-3p directly targeting AKT2, STK38L, HMGA2, ETS1 and E2F5.

Cell Mol Life Sci 2019 Feb 3;76(3):539-559. Epub 2018 Nov 3.

Institute of Applied Biotechnology, University of Applied Sciences Biberach, Hubertus-Liebrecht-Str. 35, 88400, Biberach, Germany.

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http://link.springer.com/10.1007/s00018-018-2958-x
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http://dx.doi.org/10.1007/s00018-018-2958-xDOI Listing
February 2019

miR-107 inhibits CDK6 expression, differentiation, and lipid storage in human adipocytes.

Mol Cell Endocrinol 2019 01 24;479:110-116. Epub 2018 Sep 24.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, Helsinki, Finland; Department of Anatomy, Faculty of Medicine, University of Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2018.09.007DOI Listing
January 2019

Functional and Phenotypic Characteristics of Human Leptin Receptor Mutations.

J Endocr Soc 2019 Jan 17;3(1):27-41. Epub 2018 Sep 17.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1210/js.2018-00123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293235PMC
January 2019

Early childhood BMI trajectories in monogenic obesity due to leptin, leptin receptor, and melanocortin 4 receptor deficiency.

Int J Obes (Lond) 2018 09 27;42(9):1602-1609. Epub 2018 Feb 27.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Eythstr. 24, D-89075, Ulm, Germany.

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http://dx.doi.org/10.1038/s41366-018-0049-6DOI Listing
September 2018

MiR-744-5p inducing cell death by directly targeting HNRNPC and NFIX in ovarian cancer cells.

Sci Rep 2018 Jun 13;8(1):9020. Epub 2018 Jun 13.

Institute of Applied Biotechnology, University of Applied Sciences Biberach, Hubertus-Liebrecht-Str. 35, 88400, Biberach, Germany.

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http://dx.doi.org/10.1038/s41598-018-27438-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998049PMC
June 2018

A computational biology approach of a genome-wide screen connected miRNAs to obesity and type 2 diabetes.

Mol Metab 2018 05 15;11:145-159. Epub 2018 Mar 15.

German Institute of Human Nutrition Potsdam-Rehbruecke, Department of Experimental Diabetology, 14558, Nuthetal, Germany; German Center for Diabetes Research (DZD), 85764, München-Neuherberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22128778183013
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http://dx.doi.org/10.1016/j.molmet.2018.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001404PMC
May 2018

MicroRNA-221-3p Regulates Angiopoietin-Like 8 (ANGPTL8) Expression in Adipocytes.

J Clin Endocrinol Metab 2017 11;102(11):4001-4012

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland.

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http://dx.doi.org/10.1210/jc.2017-00453DOI Listing
November 2017

Estimated prevalence of potentially damaging variants in the leptin gene.

Mol Cell Pediatr 2017 Nov 3;4(1):10. Epub 2017 Nov 3.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Eythstr. 24, D-89075, Ulm, Germany.

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http://dx.doi.org/10.1186/s40348-017-0074-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5670095PMC
November 2017

Activated macrophages control human adipocyte mitochondrial bioenergetics via secreted factors.

Mol Metab 2017 10 19;6(10):1226-1239. Epub 2017 Jul 19.

Institute of Diabetes and Regeneration Research, Helmholtz Zentrum Muenchen, German Research Center for Environmental Health (GmbH), Neuherberg, Germany; German Center for Diabetes Research (DZD), Neuherberg, Germany; Medizinische Klinik und Poliklinik IV, Klinikum der LMU, 80336 München, Germany.

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http://dx.doi.org/10.1016/j.molmet.2017.07.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5641636PMC
October 2017

Trail (TNF-related apoptosis-inducing ligand) induces an inflammatory response in human adipocytes.

Sci Rep 2017 07 18;7(1):5691. Epub 2017 Jul 18.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatric and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1038/s41598-017-05932-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5515939PMC
July 2017

Functional Significance and Predictive Value of MicroRNAs in Pediatric Obesity: Tiny Molecules with Huge Impact?

Horm Res Paediatr 2016 10;86(1):3-10. Epub 2016 May 10.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1159/000444677DOI Listing
April 2017

miR-146a-mediated suppression of the inflammatory response in human adipocytes.

Sci Rep 2016 12 6;6:38339. Epub 2016 Dec 6.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatric and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1038/srep38339DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5138634PMC
December 2016

TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors.

Cell Death Dis 2016 10 13;7(10):e2412. Epub 2016 Oct 13.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatric and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.

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http://dx.doi.org/10.1038/cddis.2016.286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133965PMC
October 2016

Resveratrol inhibits lipogenesis of 3T3-L1 and SGBS cells by inhibition of insulin signaling and mitochondrial mass increase.

Biochim Biophys Acta 2016 Jun 8;1857(6):643-52. Epub 2016 Mar 8.

Univ. Grenoble Alpes, Laboratory for Fundamental and Applied Bioenergetics (LBFA), Grenoble, France; Inserm U1055, Grenoble, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbabio.2016.03.009DOI Listing
June 2016

MicroRNA-192* impairs adipocyte triglyceride storage.

Biochim Biophys Acta 2016 Apr 30;1861(4):342-51. Epub 2015 Dec 30.

Minerva Foundation Institute for Medical Research, Biomedicum 2U, FI-00290 Helsinki, Finland; Department of Anatomy, Faculty of Medicine, University of Helsinki, FI-00014 Helsinki, Finland. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2015.12.019DOI Listing
April 2016

Regulation of Angiopoietin-Like Proteins (ANGPTLs) 3 and 8 by Insulin.

J Clin Endocrinol Metab 2015 Oct 23;100(10):E1299-307. Epub 2015 Jul 23.

Minerva Foundation Institute for Medical Research (P.A.N.H., J.S., S.S., R.M., J.P., V.M.O., H.J.-J.), FI-00290 Helsinki, Finland; Public Health Genomics Unit (J.S., J.M., C.E., M.J.), National Institute for Health and Welfare, Helsinki, FI-00290 Helsinki, Finland; Department of Medicine (S.S.), FI-00014 University of Helsinki, Helsinki, Finland; Department of Internal Medicine (F.Q.), University of Texas Southwestern Medical Center, Dallas, Texas 75390; Haartman Institute (A.P., O.R.), FI-00014 University of Helsinki, FI-00029 Helsinki, Finland; Department of Surgery (M.L.), Helsinki University Central Hospital, University of Helsinki, FI-00029 Helsinki, Finland; Department of Biochemistry and Cancer Biology and Center for Diabetes and Endocrine Research (C.M.S.), University of Toledo College of Medicine, Toledo, Ohio 43614; Division of Paediatric Endocrinology and Diabetes, Department of Paediatrics and Adolescent Medicine (P.F.-P., M.W.), University of Ulm, D-89075 Ulm Germany.

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http://dx.doi.org/10.1210/jc.2015-1254DOI Listing
October 2015

Severe Early-Onset Obesity Due to Bioinactive Leptin Caused by a p.N103K Mutation in the Leptin Gene.

J Clin Endocrinol Metab 2015 Sep 17;100(9):3227-30. Epub 2015 Jul 17.

Division of Pediatric Endocrinology and Diabetes (M.W., J.-B.F., J.v.S., F.D., C.D., A.M., P.F.-P.), and Department of Pediatrics and Adolescent Medicine (G.L., K.-M.D.), University Medical Center Ulm, 89075 Ulm, Germany; Clinical Genetics Department (I.M., M.E.), National Research Center, Cairo 12311, Egypt; Institute of Pharmacology and Toxicology (P.G., B.M.), University Medical Center Ulm, 89081 Ulm, Germany; and University of Cambridge Metabolic Research Laboratories (V.M., J.M.K., I.S.F.), Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge CB2 0QQ, United Kingdom.

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http://dx.doi.org/10.1210/jc.2015-2263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570156PMC
September 2015

TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation.

FASEB J 2015 Jul 9;29(7):3065-75. Epub 2015 Apr 9.

*Division of Pediatric Endocrinology and Diabetes and Department of Pediatrics and Adolescent Medicine, Ulm Medical Center, Ulm, Germany

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http://dx.doi.org/10.1096/fj.14-267278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4478800PMC
July 2015

Endocrine and Metabolic Effects of Adipose Tissue in Children and Adolescents.

Zdr Varst 2015 Jun 13;54(2):131-8. Epub 2015 Mar 13.

Universitätsklinikum Ulm, Eythstr. 24, 89070 Ulm, Germany.

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http://dx.doi.org/10.1515/sjph-2015-0020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820166PMC
June 2015

Obesity and inflammation: reduced cytokine expression due to resveratrol in a human in vitro model of inflamed adipose tissue.

Front Pharmacol 2015 14;6:79. Epub 2015 Apr 14.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center Ulm, Germany.

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http://dx.doi.org/10.3389/fphar.2015.00079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396198PMC
April 2015

Toll-like receptor 5 in obesity: the role of gut microbiota and adipose tissue inflammation.

Obesity (Silver Spring) 2015 Mar 22;23(3):581-90. Epub 2015 Jan 22.

Department of Health Sciences, University of Jyväskylä, Jyväskylä, Finland; Department of Medical Microbiology and Immunology, University of Turku, Turku, Finland.

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http://doi.wiley.com/10.1002/oby.20993
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http://dx.doi.org/10.1002/oby.20993DOI Listing
March 2015

Establishment of lipofection for studying miRNA function in human adipocytes.

PLoS One 2014 21;9(5):e98023. Epub 2014 May 21.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0098023PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4029777PMC
January 2015

Biologically inactive leptin and early-onset extreme obesity.

N Engl J Med 2015 Jan;372(1):48-54

From the Division of Pediatric Endocrinology and Diabetes (M.W., J.-B.F., B.L., P.F.-P.), Department of Pediatrics and Adolescent Medicine (G.L., K.-M.D.), and the Institute of Pharmacology and Toxicology (P.V., P.G., B.M.), University of Ulm, Ulm; and Endokrinologische Schwerpunktpraxis für Kinder- und Jugendliche, Gauting (U.K.-K.) - both in Germany.

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http://dx.doi.org/10.1056/NEJMoa1406653DOI Listing
January 2015

Monogenic forms of childhood obesity due to mutations in the leptin gene.

Mol Cell Pediatr 2014 Dec 4;1(1). Epub 2014 Sep 4.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, 89075, Germany.

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http://dx.doi.org/10.1186/s40348-014-0003-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644131PMC
December 2014

Resveratrol suppresses PAI-1 gene expression in a human in vitro model of inflamed adipose tissue.

Oxid Med Cell Longev 2013 2;2013:793525. Epub 2013 Jun 2.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Ulm, Germany.

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http://dx.doi.org/10.1155/2013/793525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3684090PMC
August 2014

Spare mitochondrial respiratory capacity permits human adipocytes to maintain ATP homeostasis under hypoglycemic conditions.

FASEB J 2014 Feb 7;28(2):761-70. Epub 2013 Nov 7.

2Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Institute for Diabetes and Regeneration Research, Ingolstaedter Landstr. 1, 85764 Neuherberg, Germany.

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http://www.fasebj.org/doi/10.1096/fj.13-238725
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http://dx.doi.org/10.1096/fj.13-238725DOI Listing
February 2014

Up-regulation of Bcl-2 during adipogenesis mediates apoptosis resistance in human adipocytes.

Mol Cell Endocrinol 2014 Jan 26;382(1):368-376. Epub 2013 Oct 26.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, 89075 Ulm, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2013.10.024DOI Listing
January 2014

High content analysis of differentiation and cell death in human adipocytes.

Cytometry A 2013 Oct 11;83(10):933-43. Epub 2013 Jul 11.

Department of Biophysics and Cell Biology, Medical and Health Science Center, University of Debrecen, Debrecen, Hungary.

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http://dx.doi.org/10.1002/cyto.a.22333DOI Listing
October 2013

Interleukin-1β downregulates RBP4 secretion in human adipocytes.

PLoS One 2013 27;8(2):e57796. Epub 2013 Feb 27.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University, Ulm, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0057796PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3584036PMC
September 2013

Absence of CC chemokine receptors 2a and 2b from human adipose lineage cells.

Mol Cell Endocrinol 2013 Apr 29;369(1-2):72-85. Epub 2013 Jan 29.

Institute of Pharmacology and Toxicology, Ulm University Medical Center, Ulm, Germany.

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http://dx.doi.org/10.1016/j.mce.2013.01.008DOI Listing
April 2013

Resveratrol-induced changes of the human adipocyte secretion profile.

J Proteome Res 2012 Sep 27;11(9):4733-43. Epub 2012 Aug 27.

Department of Human Biology, NUTRIM School for Nutrition, Toxicology and Metabolism, Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1021/pr300539bDOI Listing
September 2012

THP-1 Macrophages and SGBS Adipocytes - A New Human in vitro Model System of Inflamed Adipose Tissue.

Front Endocrinol (Lausanne) 2011 14;2:89. Epub 2011 Dec 14.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Ulm, Germany.

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http://dx.doi.org/10.3389/fendo.2011.00089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3355855PMC
August 2012

Differential function of Akt1 and Akt2 in human adipocytes.

Mol Cell Endocrinol 2012 Jul 29;358(1):135-43. Epub 2012 Mar 29.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, Ulm University Medical Center, Eythstr. 24, 89075 Ulm, Germany.

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http://dx.doi.org/10.1016/j.mce.2012.03.018DOI Listing
July 2012

RBP4: a controversial adipokine.

Eur J Endocrinol 2011 Nov 10;165(5):703-11. Epub 2011 Aug 10.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1530/EJE-11-0431DOI Listing
November 2011

Downregulation of FLIP by cycloheximide sensitizes human fat cells to CD95-induced apoptosis.

Exp Cell Res 2011 Sep 2;317(15):2200-9. Epub 2011 Jul 2.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Ulm, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S001448271100272
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http://dx.doi.org/10.1016/j.yexcr.2011.06.016DOI Listing
September 2011

Targeted deletion of adipocytes by apoptosis leads to adipose tissue recruitment of alternatively activated M2 macrophages.

Endocrinology 2011 Aug 21;152(8):3074-81. Epub 2011 Jun 21.

University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-8549, USA.

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https://academic.oup.com/endo/article-lookup/doi/10.1210/en.
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http://dx.doi.org/10.1210/en.2011-1031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138241PMC
August 2011

An inflammatory micro-environment promotes human adipocyte apoptosis.

Mol Cell Endocrinol 2011 Jun 9;339(1-2):105-13. Epub 2011 Apr 9.

Division of Pediatric Endocrinology, Diabetes and Obesity Unit, Department of Pediatrics and Adolescent Medicine, Ulm University, Eythstr. 24, 89075 Ulm, Germany.

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http://dx.doi.org/10.1016/j.mce.2011.04.004DOI Listing
June 2011

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index.

Authors:
Elizabeth K Speliotes Cristen J Willer Sonja I Berndt Keri L Monda Gudmar Thorleifsson Anne U Jackson Hana Lango Allen Cecilia M Lindgren Jian'an Luan Reedik Mägi Joshua C Randall Sailaja Vedantam Thomas W Winkler Lu Qi Tsegaselassie Workalemahu Iris M Heid Valgerdur Steinthorsdottir Heather M Stringham Michael N Weedon Eleanor Wheeler Andrew R Wood Teresa Ferreira Robert J Weyant Ayellet V Segrè Karol Estrada Liming Liang James Nemesh Ju-Hyun Park Stefan Gustafsson Tuomas O Kilpeläinen Jian Yang Nabila Bouatia-Naji Tõnu Esko Mary F Feitosa Zoltán Kutalik Massimo Mangino Soumya Raychaudhuri Andre Scherag Albert Vernon Smith Ryan Welch Jing Hua Zhao Katja K Aben Devin M Absher Najaf Amin Anna L Dixon Eva Fisher Nicole L Glazer Michael E Goddard Nancy L Heard-Costa Volker Hoesel Jouke-Jan Hottenga Asa Johansson Toby Johnson Shamika Ketkar Claudia Lamina Shengxu Li Miriam F Moffatt Richard H Myers Narisu Narisu John R B Perry Marjolein J Peters Michael Preuss Samuli Ripatti Fernando Rivadeneira Camilla Sandholt Laura J Scott Nicholas J Timpson Jonathan P Tyrer Sophie van Wingerden Richard M Watanabe Charles C White Fredrik Wiklund Christina Barlassina Daniel I Chasman Matthew N Cooper John-Olov Jansson Robert W Lawrence Niina Pellikka Inga Prokopenko Jianxin Shi Elisabeth Thiering Helene Alavere Maria T S Alibrandi Peter Almgren Alice M Arnold Thor Aspelund Larry D Atwood Beverley Balkau Anthony J Balmforth Amanda J Bennett Yoav Ben-Shlomo Richard N Bergman Sven Bergmann Heike Biebermann Alexandra I F Blakemore Tanja Boes Lori L Bonnycastle Stefan R Bornstein Morris J Brown Thomas A Buchanan Fabio Busonero Harry Campbell Francesco P Cappuccio Christine Cavalcanti-Proença Yii-Der Ida Chen Chih-Mei Chen Peter S Chines Robert Clarke Lachlan Coin John Connell Ian N M Day Martin den Heijer Jubao Duan Shah Ebrahim Paul Elliott Roberto Elosua Gudny Eiriksdottir Michael R Erdos Johan G Eriksson Maurizio F Facheris Stephan B Felix Pamela Fischer-Posovszky Aaron R Folsom Nele Friedrich Nelson B Freimer Mao Fu Stefan Gaget Pablo V Gejman Eco J C Geus Christian Gieger Anette P Gjesing Anuj Goel Philippe Goyette Harald Grallert Jürgen Grässler Danielle M Greenawalt Christopher J Groves Vilmundur Gudnason Candace Guiducci Anna-Liisa Hartikainen Neelam Hassanali Alistair S Hall Aki S Havulinna Caroline Hayward Andrew C Heath Christian Hengstenberg Andrew A Hicks Anke Hinney Albert Hofman Georg Homuth Jennie Hui Wilmar Igl Carlos Iribarren Bo Isomaa Kevin B Jacobs Ivonne Jarick Elizabeth Jewell Ulrich John Torben Jørgensen Pekka Jousilahti Antti Jula Marika Kaakinen Eero Kajantie Lee M Kaplan Sekar Kathiresan Johannes Kettunen Leena Kinnunen Joshua W Knowles Ivana Kolcic Inke R König Seppo Koskinen Peter Kovacs Johanna Kuusisto Peter Kraft Kirsti Kvaløy Jaana Laitinen Olivier Lantieri Chiara Lanzani Lenore J Launer Cecile Lecoeur Terho Lehtimäki Guillaume Lettre Jianjun Liu Marja-Liisa Lokki Mattias Lorentzon Robert N Luben Barbara Ludwig Paolo Manunta Diana Marek Michel Marre Nicholas G Martin Wendy L McArdle Anne McCarthy Barbara McKnight Thomas Meitinger Olle Melander David Meyre Kristian Midthjell Grant W Montgomery Mario A Morken Andrew P Morris Rosanda Mulic Julius S Ngwa Mari Nelis Matt J Neville Dale R Nyholt Christopher J O'Donnell Stephen O'Rahilly Ken K Ong Ben Oostra Guillaume Paré Alex N Parker Markus Perola Irene Pichler Kirsi H Pietiläinen Carl G P Platou Ozren Polasek Anneli Pouta Suzanne Rafelt Olli Raitakari Nigel W Rayner Martin Ridderstråle Winfried Rief Aimo Ruokonen Neil R Robertson Peter Rzehak Veikko Salomaa Alan R Sanders Manjinder S Sandhu Serena Sanna Jouko Saramies Markku J Savolainen Susann Scherag Sabine Schipf Stefan Schreiber Heribert Schunkert Kaisa Silander Juha Sinisalo David S Siscovick Jan H Smit Nicole Soranzo Ulla Sovio Jonathan Stephens Ida Surakka Amy J Swift Mari-Liis Tammesoo Jean-Claude Tardif Maris Teder-Laving Tanya M Teslovich John R Thompson Brian Thomson Anke Tönjes Tiinamaija Tuomi Joyce B J van Meurs Gert-Jan van Ommen Vincent Vatin Jorma Viikari Sophie Visvikis-Siest Veronique Vitart Carla I G Vogel Benjamin F Voight Lindsay L Waite Henri Wallaschofski G Bragi Walters Elisabeth Widen Susanna Wiegand Sarah H Wild Gonneke Willemsen Daniel R Witte Jacqueline C Witteman Jianfeng Xu Qunyuan Zhang Lina Zgaga Andreas Ziegler Paavo Zitting John P Beilby I Sadaf Farooqi Johannes Hebebrand Heikki V Huikuri Alan L James Mika Kähönen Douglas F Levinson Fabio Macciardi Markku S Nieminen Claes Ohlsson Lyle J Palmer Paul M Ridker Michael Stumvoll Jacques S Beckmann Heiner Boeing Eric Boerwinkle Dorret I Boomsma Mark J Caulfield Stephen J Chanock Francis S Collins L Adrienne Cupples George Davey Smith Jeanette Erdmann Philippe Froguel Henrik Grönberg Ulf Gyllensten Per Hall Torben Hansen Tamara B Harris Andrew T Hattersley Richard B Hayes Joachim Heinrich Frank B Hu Kristian Hveem Thomas Illig Marjo-Riitta Jarvelin Jaakko Kaprio Fredrik Karpe Kay-Tee Khaw Lambertus A Kiemeney Heiko Krude Markku Laakso Debbie A Lawlor Andres Metspalu Patricia B Munroe Willem H Ouwehand Oluf Pedersen Brenda W Penninx Annette Peters Peter P Pramstaller Thomas Quertermous Thomas Reinehr Aila Rissanen Igor Rudan Nilesh J Samani Peter E H Schwarz Alan R Shuldiner Timothy D Spector Jaakko Tuomilehto Manuela Uda André Uitterlinden Timo T Valle Martin Wabitsch Gérard Waeber Nicholas J Wareham Hugh Watkins James F Wilson Alan F Wright M Carola Zillikens Nilanjan Chatterjee Steven A McCarroll Shaun Purcell Eric E Schadt Peter M Visscher Themistocles L Assimes Ingrid B Borecki Panos Deloukas Caroline S Fox Leif C Groop Talin Haritunians David J Hunter Robert C Kaplan Karen L Mohlke Jeffrey R O'Connell Leena Peltonen David Schlessinger David P Strachan Cornelia M van Duijn H-Erich Wichmann Timothy M Frayling Unnur Thorsteinsdottir Gonçalo R Abecasis Inês Barroso Michael Boehnke Kari Stefansson Kari E North Mark I McCarthy Joel N Hirschhorn Erik Ingelsson Ruth J F Loos

Nat Genet 2010 Nov 10;42(11):937-48. Epub 2010 Oct 10.

Metabolism Initiative and Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA.

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http://www.genome.gov/pages/research/dir/bmistudy.pdf
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http://www.nature.com/doifinder/10.1038/ng.686
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http://dx.doi.org/10.1038/ng.686DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014648PMC
November 2010

Human SGBS cells - a unique tool for studies of human fat cell biology.

Obes Facts 2008 14;1(4):184-9. Epub 2008 Aug 14.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Ulm, Germany.

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http://dx.doi.org/10.1159/000145784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452113PMC
July 2010

Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner.

Am J Clin Nutr 2010 Jul 12;92(1):5-15. Epub 2010 May 12.

Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.3945/ajcn.2009.28435DOI Listing
July 2010

A new missense mutation in the leptin gene causes mild obesity and hypogonadism without affecting T cell responsiveness.

J Clin Endocrinol Metab 2010 Jun 9;95(6):2836-40. Epub 2010 Apr 9.

Division of Pediatric Endocrinology and Diabetes, University of Ulm, Eythstrasse 24, 89075 Ulm, Germany.

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http://dx.doi.org/10.1210/jc.2009-2466DOI Listing
June 2010

Pioglitazone reduces inflammatory responses of human adipocytes to factors secreted by monocytes/macrophages.

Am J Physiol Endocrinol Metab 2009 May 24;296(5):E1076-84. Epub 2009 Feb 24.

Phoenix Veterans Affairs Health Care System, Phoenix, AZ 85012-1892, USA.

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http://dx.doi.org/10.1152/ajpendo.91013.2008DOI Listing
May 2009

Role of CD95-mediated adipocyte loss in autoimmune lipodystrophy.

J Clin Endocrinol Metab 2006 Mar 20;91(3):1129-35. Epub 2005 Dec 20.

Pediatric Endocrinology, Department of Pediatrics and Adolescent Medicine, University of Ulm, Prittwitzstrasse 43, 89075 Ulm, Germany.

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http://dx.doi.org/10.1210/jc.2005-0737DOI Listing
March 2006

Inhibition of death-receptor mediated apoptosis in human adipocytes by the insulin-like growth factor I (IGF-I)/IGF-I receptor autocrine circuit.

Endocrinology 2004 Apr 22;145(4):1849-59. Epub 2003 Dec 22.

Department of Pediatrics and Adolescent Medicine, University of Ulm, Germany.

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http://dx.doi.org/10.1210/en.2003-0985DOI Listing
April 2004

[Lipodystrophies].

Klin Padiatr 2002 May-Jun;214(3):99-103

Universitätskinderklinik und Poliklinik, Ulm, Germany.

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http://dx.doi.org/10.1055/s-2002-30142DOI Listing
September 2002