Publications by authors named "Pamela Bielli"

24Publications

Splicing Dysregulation as Oncogenic Driver and Passenger Factor in Brain Tumors.

Cells 2019 12 18;9(1). Epub 2019 Dec 18.

Laboratory of Neuroembryology, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells9010010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7016899PMC
December 2019

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization.

Nucleic Acids Res 2020 01;48(2):633-645

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Heart, Rome 00168, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkz1117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6954450PMC
January 2020

c-MYC empowers transcription and productive splicing of the oncogenic splicing factor Sam68 in cancer.

Nucleic Acids Res 2019 07;47(12):6160-6171

Laboratory of Neuroembryology, IRCCS Fondazione Santa Lucia, 00143 Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkz344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6614821PMC
July 2019

Functional Interaction between U1snRNP and Sam68 Insures Proper 3' End Pre-mRNA Processing during Germ Cell Differentiation.

Cell Rep 2019 03;26(11):2929-2941.e5

Institute of Human Anatomy and Cell Biology, Catholic University of the Sacred Hearth, 00168 Rome, Italy; IRCCS Fondazione Santa Lucia, 00143 Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2019.02.058DOI Listing
March 2019

Alternative polyadenylation of ZEB1 promotes its translation during genotoxic stress in pancreatic cancer cells.

Cell Death Dis 2017 11 9;8(11):e3168. Epub 2017 Nov 9.

Department of Biomedicine and Prevention, Section of Anatomy, University of Rome 'Tor Vergata', Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/cddis.2017.562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775412PMC
November 2017

Analysis of Interaction between RNA Binding Proteins and Their RNA Targets by UV Cross-linking and Immunoprecipitation (CLIP) Method.

Bio Protoc 2017 May;7(10)

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21769/BioProtoc.2274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448666PMC
May 2017

An Orchestrated Intron Retention Program in Meiosis Controls Timely Usage of Transcripts during Germ Cell Differentiation.

Dev Cell 2017 04 30;41(1):82-93.e4. Epub 2017 Mar 30.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy; Laboratories of Neuroembryology, Fondazione Santa Lucia IRCCS, 00143 Rome, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2017.03.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392497PMC
April 2017

Fine-tuning of ULK1 mRNA and protein levels is required for autophagy oscillation.

J Cell Biol 2016 Dec 8;215(6):841-856. Epub 2016 Dec 8.

Department of Pediatric Hematology and Oncology, Istituto di Ricovero e Cura a Carattere Scientifico Bambino Gesù Children's Hospital, 00146 Rome, Italy

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.201605089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166502PMC
December 2016

MIR retroposon exonization promotes evolutionary variability and generates species-specific expression of IGF-1 splice variants.

Biochim Biophys Acta 2016 May 19;1859(5):757-68. Epub 2016 Apr 19.

Department of Biomolecular Sciences, University of Urbino Carlo Bo, 61029 Urbino, Italy; IIM, Interuniversity Institute of Myology, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbagrm.2016.03.014DOI Listing
May 2016

The interplay between DNA damage response and RNA processing: the unexpected role of splicing factors as gatekeepers of genome stability.

Front Genet 2015 15;6:142. Epub 2015 Apr 15.

Department of Biomedicine and Prevention, University of Rome Tor Vergata , Rome, Italy ; Laboratory of Neuroembryology, Fondazione Santa Lucia , Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fgene.2015.00142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4397863PMC
April 2015

Regulation of BCL-X splicing reveals a role for the polypyrimidine tract binding protein (PTBP1/hnRNP I) in alternative 5' splice site selection.

Nucleic Acids Res 2014 Oct 7;42(19):12070-81. Epub 2014 Oct 7.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, 00133 Rome, Italy Laboratory of Neuroembryology, Fondazione Santa Lucia, 00143 Rome, Italy

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gku922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231771PMC
October 2014

The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis.

EMBO Rep 2014 Apr 10;15(4):419-27. Epub 2014 Feb 10.

Department of Biomedicine and Prevention, University of Rome Tor Vergata, Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/embr.201338241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989673PMC
April 2014

The RNA-binding protein Sam68 is a multifunctional player in human cancer.

Endocr Relat Cancer 2011 Aug 1;18(4):R91-R102. Epub 2011 Jul 1.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/ERC-11-0041DOI Listing
August 2011

Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells.

Carcinogenesis 2008 Dec 22;29(12):2279-88. Epub 2008 Sep 22.

Department of Public Health and Cell Biology, University of Rome Tor Vergata, Rome, Italy.

View Article

Download full-text PDF

Source
https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
Publisher Site
http://dx.doi.org/10.1093/carcin/bgn221DOI Listing
December 2008

GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway.

Mol Microbiol 2006 Mar;59(5):1576-90

Department of Biology, University of Tor Vergata Rome, Viale Della Ricerca Scientifica, 00133-Rome, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1365-2958.2006.05041.xDOI Listing
March 2006

Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p.

EMBO J 2002 Dec;21(23):6397-408

Institute of Microbiology and Genetics, Vienna Biocenter, University of Vienna, Dr Bohrgasse 9, A-1030 Vienna, Austria.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136954PMC
http://dx.doi.org/10.1093/emboj/cdf650DOI Listing
December 2002