Pamala A Jacobson

Pamala A Jacobson

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Pamala A Jacobson

Pamala A Jacobson

Publications by authors named "Pamala A Jacobson"

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Precision medicine, agriculture, and genome editing: science and ethics.

Ann N Y Acad Sci 2019 Nov 13. Epub 2019 Nov 13.

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota.

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http://dx.doi.org/10.1111/nyas.14266DOI Listing
November 2019

Comparative Evaluation of Median Versus Youden Index Dichotomization Methods: Exposure-Response Analysis of Mycophenolic Acid and Acyl-Glucuronide Metabolite.

Eur J Drug Metab Pharmacokinet 2019 Oct;44(5):629-638

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s13318-019-00550-2DOI Listing
October 2019

Pharmacogenomics of Medications Commonly Used in the Intensive Care Unit.

Front Pharmacol 2018 4;9:1436. Epub 2018 Dec 4.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, United States.

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http://dx.doi.org/10.3389/fphar.2018.01436DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6289166PMC
December 2018

Mycophenolic Acid and Its Metabolites in Kidney Transplant Recipients: A Semimechanistic Enterohepatic Circulation Model to Improve Estimating Exposure.

J Clin Pharmacol 2018 05 12;58(5):628-639. Epub 2018 Jan 12.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1002/jcph.1064DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910266PMC
May 2018

Tacrolimus Elimination in Four Patients With a CYP3A5*3/*3 CYP3A4*22/*22 Genotype Combination.

Pharmacotherapy 2018 May 26. Epub 2018 May 26.

Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, Minnesota.

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http://dx.doi.org/10.1002/phar.2131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265082PMC
May 2018

Genetics of acute rejection after kidney transplantation.

Transpl Int 2018 03 8;31(3):263-277. Epub 2017 Nov 8.

Department of Nephrology, Minneapolis Medical Research Foundation, Minneapolis, MN, USA.

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http://dx.doi.org/10.1111/tri.13084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260834PMC
March 2018

Influence of Kidney Transplant Status on Warfarin Dose, Anticoagulation Control, and Risk of Hemorrhage.

Pharmacotherapy 2017 Nov 2;37(11):1366-1373. Epub 2017 Nov 2.

Neurology, University of Alabama at Birmingham, Birmingham, Alabama.

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http://dx.doi.org/10.1002/phar.2032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681429PMC
November 2017

Concepts of Genomics in Kidney Transplantation.

Curr Transplant Rep 2017 Jun 24;4(2):116-123. Epub 2017 May 24.

Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN.

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http://dx.doi.org/10.1007/s40472-017-0153-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673265PMC
June 2017

Rifampin-sirolimus-voriconazole interaction in a hematopoietic cell transplant recipient.

J Oncol Pharm Pract 2017 Jan 8;23(1):75-79. Epub 2016 Jul 8.

2 Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, Minneapolis, MN, USA.

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http://dx.doi.org/10.1177/1078155215624263DOI Listing
January 2017

Pharmacokinetic-pharmacodynamic modelling of acute N-terminal pro B-type natriuretic peptide after doxorubicin infusion in breast cancer.

Br J Clin Pharmacol 2016 09 3;82(3):773-83. Epub 2016 Jun 3.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN, 55455, USA.

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http://dx.doi.org/10.1111/bcp.12989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5338127PMC
September 2016

Differentially expressed gene transcripts using RNA sequencing from the blood of immunosuppressed kidney allograft recipients.

PLoS One 2015 6;10(5):e0125045. Epub 2015 May 6.

Minneapolis Medical Research Foundation, Minneapolis, Minnesota, United States of America; Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, Minnesota, United States of America; Department of Epidemiology and Community Health, University of Minnesota School of Medicine, Minneapolis, Minnesota, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0125045PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4422721PMC
April 2016

Multigene predictors of tacrolimus exposure in kidney transplant recipients.

Pharmacogenomics 2015 Jul 12;16(8):841-54. Epub 2015 Jun 12.

Department of Experimental & Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.

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https://www.futuremedicine.com/doi/10.2217/pgs.15.42
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http://dx.doi.org/10.2217/pgs.15.42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4527535PMC
July 2015

Telomere length of recipients and living kidney donors and chronic graft dysfunction in kidney transplants.

Transplantation 2014 Feb;97(3):325-9

1 College of Pharmacy, University of Minnesota, Minneapolis, MN. 2 Division of Biostatistics, University of Minnesota, Minneapolis, MN. 3 Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN. 4 Minneapolis Medical Research Foundation, Minneapolis, MN. 5 Department of Laboratory Medicine and Pathology, University of Minnesota, Minnesota, MN. 6 Department of Surgery, University of Minnesota, Minneapolis, MN. 7 Address correspondence to: William S. Oetting, Ph.D., Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN 55455.

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http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
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http://dx.doi.org/10.1097/01.TP.0000436705.87898.88DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104656PMC
February 2014

Inflammation in the setting of chronic allograft dysfunction post-kidney transplant: phenotype and genotype.

Clin Transplant 2013 May-Jun;27(3):348-58. Epub 2013 Jan 27.

Nephrology Division, Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN 55415-1829, USA.

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http://doi.wiley.com/10.1111/ctr.12074
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http://dx.doi.org/10.1111/ctr.12074DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3647022PMC
January 2014

Tacrolimus trough levels after month 3 as a predictor of acute rejection following kidney transplantation: a lesson learned from DeKAF Genomics.

Transpl Int 2013 Oct 24;26(10):982-9. Epub 2013 Jul 24.

Nephrology Division, Department of Medicine, Hennepin County Medical Center, University of Minnesota, Minneapolis, MN, USA; Department of Epidemiology & Community Health, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1111/tri.12155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787982PMC
October 2013

Obesity effects on cyclophosphamide-induced DNA damage in hematopoietic cell transplant recipients.

In Vivo 2012 Sep-Oct;26(5):853-7

University of Minnesota, College of Pharmacy, Department of Experimental and Clinical Pharmacology, 308 Harvard Street SE, 7-115C WDH, Minneapolis, MN 55443, USA.

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January 2013

Validation of tacrolimus equation to predict troughs using genetic and clinical factors.

Pharmacogenomics 2012 Jul;13(10):1141-7

Department of Experimental & Clinical Pharmacology, 717 Delaware Street, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.2217/pgs.12.98DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579500PMC
July 2012

Formation of cyclophosphamide specific DNA adducts in hematological diseases.

Pediatr Blood Cancer 2012 May 25;58(5):708-14. Epub 2011 Jul 25.

Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, Minnesota 55455, USA.

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http://doi.wiley.com/10.1002/pbc.23254
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http://dx.doi.org/10.1002/pbc.23254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204332PMC
May 2012

Cytotoxic purine nucleoside analogues bind to A1, A2A, and A3 adenosine receptors.

Naunyn Schmiedebergs Arch Pharmacol 2012 May 17;385(5):519-25. Epub 2012 Jan 17.

College of Pharmacy, Department of Experimental and Clinical Pharmacology, University of Minnesota, 308 Harvard ST SE, Minneapolis, MN, USA.

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http://dx.doi.org/10.1007/s00210-011-0719-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831620PMC
May 2012

Dosing equation for tacrolimus using genetic variants and clinical factors.

Br J Clin Pharmacol 2011 Dec;72(6):948-57

Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1111/j.1365-2125.2011.04039.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244642PMC
December 2011

Genetic determinants of mycophenolate-related anemia and leukopenia after transplantation.

Transplantation 2011 Feb;91(3):309-16

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1097/TP.0b013e318200e971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711617PMC
February 2011

Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.

Eur J Clin Pharmacol 2008 Nov 21;64(11):1047-56. Epub 2008 Jun 21.

Department of Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN 55455, USA.

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http://link.springer.com/content/pdf/10.1007/s00228-008-0501
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http://link.springer.com/10.1007/s00228-008-0501-y
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http://dx.doi.org/10.1007/s00228-008-0501-yDOI Listing
November 2008

Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation.

J Clin Pharmacol 2008 Sep 17;48(9):1052-62. Epub 2008 Jul 17.

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.

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http://dx.doi.org/10.1177/0091270008321940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204946PMC
September 2008

Exposure-response relationships for oxaliplatin-treated colon cancer cells.

Anticancer Drugs 2008 Jan;19(1):37-44

Department of Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis 55455, USA.

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http://dx.doi.org/10.1097/CAD.0b013e3282f07791DOI Listing
January 2008

A limited sampling model for estimation of total and unbound mycophenolic acid (MPA) area under the curve (AUC) in hematopoietic cell transplantation (HCT).

Ther Drug Monit 2006 Jun;28(3):394-401

Experimental and Clinical Pharmacology, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1097/01.ftd.0000211821.73231.8aDOI Listing
June 2006

Mycophenolate mofetil in islet cell transplant: variable pharmacokinetics but good correlation between total and unbound concentrations.

J Clin Pharmacol 2005 Aug;45(8):901-9

Experimental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA.

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http://doi.wiley.com/10.1177/0091270005278599
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http://dx.doi.org/10.1177/0091270005278599DOI Listing
August 2005

Posttransplant day significantly influences pharmacokinetics of cyclosporine after hematopoietic stem cell transplantation.

Biol Blood Marrow Transplant 2003 May;9(5):304-11

Experiemental and Clinical Pharmacology, College of Pharmacy, University of Minnesota, Minneapolis 55455, USA.

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http://dx.doi.org/10.1016/s1083-8791(03)00076-4DOI Listing
May 2003