Publications by authors named "Pal Stenmark"

88Publications

Structural and functional analysis of the inhibition of equine glutathione transferase A3-3 by organotin endocrine disrupting pollutants.

Environ Pollut 2020 Oct 29:115960. Epub 2020 Oct 29.

Department of Biochemistry and Biophysics, Stockholm University, SE-10691, Stockholm, Sweden; Department of Experimental Medical Science, Lund University, SE-22100, Lund, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.envpol.2020.115960DOI Listing
October 2020

Structural and Biochemical Characterization of Botulinum Neurotoxin Subtype B2 Binding to Its Receptors.

Toxins (Basel) 2020 Sep 17;12(9). Epub 2020 Sep 17.

Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.3390/toxins12090603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7551386PMC
September 2020

Crystal structures of human PAICS reveal substrate and product binding of an emerging cancer target.

J Biol Chem 2020 Aug 22;295(33):11656-11668. Epub 2020 Jun 22.

Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden

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http://dx.doi.org/10.1074/jbc.RA120.013695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7450103PMC
August 2020

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.

PLoS Biol 2020 03 17;18(3):e3000618. Epub 2020 Mar 17.

Department of Urology, Boston Children's Hospital, Department of Microbiology and Department of Surgery, Harvard Medical School, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pbio.3000618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077807PMC
March 2020

MutT homologue 1 (MTH1) removes N6-methyl-dATP from the dNTP pool.

J Biol Chem 2020 Apr 6;295(15):4761-4772. Epub 2020 Mar 6.

Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, S-171 76 Stockholm, Sweden

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http://dx.doi.org/10.1074/jbc.RA120.012636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7152754PMC
April 2020

The First Structure of an Active Mammalian dCTPase and its Complexes With Substrate Analogs and Products.

J Mol Biol 2020 02 15;432(4):1126-1142. Epub 2020 Jan 15.

Department of Experimental Medical Science, Lund University, Lund, 221 00, Sweden; Department of Biochemistry and Biophysics, Stockholm University, Stockholm, S-106 91, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2020.01.005DOI Listing
February 2020

Structure and steroid isomerase activity of Drosophila glutathione transferase E14 essential for ecdysteroid biosynthesis.

FEBS Lett 2020 Apr 9;594(7):1187-1195. Epub 2020 Jan 9.

Department of Biochemistry and Biophysics, Stockholm University, Sweden.

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http://dx.doi.org/10.1002/1873-3468.13718DOI Listing
April 2020

Synaptotagmin Binding to Botulinum Neurotoxins.

Biochemistry 2020 02 18;59(4):491-498. Epub 2019 Dec 18.

Department of Biochemistry and Biophysics , Stockholm University , SE-106 91 Stockholm , Sweden.

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http://dx.doi.org/10.1021/acs.biochem.9b00554DOI Listing
February 2020

The Structure and Classification of Botulinum Toxins.

Handb Exp Pharmacol 2019 Dec 3. Epub 2019 Dec 3.

Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1007/164_2019_342DOI Listing
December 2019

A neurotoxin that specifically targets Anopheles mosquitoes.

Nat Commun 2019 06 28;10(1):2869. Epub 2019 Jun 28.

Department of Molecular, Cell and Systems Biology, University of California, Riverside, CA, 92521, USA.

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http://dx.doi.org/10.1038/s41467-019-10732-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6599013PMC
June 2019

Structural basis of inhibition of the human serine hydroxymethyltransferase SHMT2 by antifolate drugs.

FEBS Lett 2019 07 10;593(14):1863-1873. Epub 2019 Jun 10.

Department of Biochemistry and Biophysics, Stockholm University, Sweden.

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http://dx.doi.org/10.1002/1873-3468.13455DOI Listing
July 2019

Crystal structure of the catalytic domain of the Weissella oryzae botulinum-like toxin.

FEBS Lett 2019 06 31;593(12):1403-1410. Epub 2019 May 31.

Department of Biochemistry and Biophysics, Stockholm University, Sweden.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/1873-3468.13
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http://dx.doi.org/10.1002/1873-3468.13446DOI Listing
June 2019

Crystal Structure and Substrate Specificity of the 8-oxo-dGTP Hydrolase NUDT1 from Arabidopsis thaliana.

Biochemistry 2019 02 16;58(7):887-899. Epub 2019 Jan 16.

Department of Biochemistry and Biophysics , Stockholm University , Stockholm S-106 91 , Sweden.

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http://dx.doi.org/10.1021/acs.biochem.8b00950DOI Listing
February 2019

Cotranslational Folding of a Pentarepeat β-Helix Protein.

J Mol Biol 2018 12 27;430(24):5196-5206. Epub 2018 Oct 27.

Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden; Science for Life Laboratory Stockholm University, Box 1031, SE-171 21 Solna, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222836183073
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http://dx.doi.org/10.1016/j.jmb.2018.10.016DOI Listing
December 2018

Botulinum and Tetanus Neurotoxins.

Annu Rev Biochem 2019 06 2;88:811-837. Epub 2018 Nov 2.

Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden; email:

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https://www.annualreviews.org/doi/10.1146/annurev-biochem-01
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http://dx.doi.org/10.1146/annurev-biochem-013118-111654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7539302PMC
June 2019

Crystal Structure of Botulinum Neurotoxin A2 in Complex with the Human Protein Receptor SV2C Reveals Plasticity in Receptor Binding.

Toxins (Basel) 2018 04 12;10(4). Epub 2018 Apr 12.

Department of Biochemistry and Biophysics, Stockholm University, S-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.3390/toxins10040153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5923319PMC
April 2018

Human NUDT22 Is a UDP-Glucose/Galactose Hydrolase Exhibiting a Unique Structural Fold.

Structure 2018 02;26(2):295-303.e6

Department of Biochemistry and Biophysics, Stockholm University, 106 91 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.str.2018.01.004DOI Listing
February 2018

Identification of a Botulinum Neurotoxin-like Toxin in a Commensal Strain of Enterococcus faecium.

Cell Host Microbe 2018 Feb 27;23(2):169-176.e6. Epub 2018 Jan 27.

Department of Urology, Boston Children's Hospital, Department of Microbiology and Immunobiology and Department of Surgery, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19313128173055
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http://dx.doi.org/10.1016/j.chom.2017.12.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926203PMC
February 2018

Crystal Structures and Inhibitor Interactions of Mouse and Dog MTH1 Reveal Species-Specific Differences in Affinity.

Biochemistry 2018 02 16;57(5):593-603. Epub 2018 Jan 16.

Department of Biochemistry and Biophysics, Stockholm University , S-106 91 Stockholm, Sweden.

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http://pubs.acs.org/doi/10.1021/acs.biochem.7b01163
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http://dx.doi.org/10.1021/acs.biochem.7b01163DOI Listing
February 2018

Mechanism of Peptide Binding and Cleavage by the Human Mitochondrial Peptidase Neurolysin.

J Mol Biol 2018 02 26;430(3):348-362. Epub 2017 Nov 26.

Department of Biochemistry and Biophysics, Stockholm University, Arrhenius Laboratories for Natural Sciences, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jmb.2017.11.011DOI Listing
February 2018

Structural basis for the unique ganglioside and cell membrane recognition mechanism of botulinum neurotoxin DC.

Nat Commun 2017 11 21;8(1):1637. Epub 2017 Nov 21.

Department of Urology, Boston Children's Hospital, Harvard Medical School, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1038/s41467-017-01534-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5696347PMC
November 2017

Crystal structures of OrfX2 and P47 from a Botulinum neurotoxin OrfX-type gene cluster.

FEBS Lett 2017 11 5;591(22):3781-3792. Epub 2017 Nov 5.

Department of Biochemistry and Biophysics, Stockholm University, Sweden.

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http://dx.doi.org/10.1002/1873-3468.12889DOI Listing
November 2017

Fragment-Based Discovery and Optimization of Enzyme Inhibitors by Docking of Commercial Chemical Space.

J Med Chem 2017 10 3;60(19):8160-8169. Epub 2017 Oct 3.

Science for Life Laboratory, Department of Cell and Molecular Biology, BMC, Uppsala University , Box 596, SE-751 24 Uppsala, Sweden.

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http://dx.doi.org/10.1021/acs.jmedchem.7b01006DOI Listing
October 2017

Novel spirocyclic systems via multicomponent aza-Diels-Alder reaction.

Org Biomol Chem 2017 Sep;15(37):7758-7764

Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1039/c7ob02069dDOI Listing
September 2017

Identification and characterization of a novel botulinum neurotoxin.

Nat Commun 2017 08 3;8:14130. Epub 2017 Aug 3.

Department of Biochemistry and Biophysics, Stockholm University, SE-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1038/ncomms14130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543303PMC
August 2017

Engineered botulinum neurotoxin B with improved efficacy for targeting human receptors.

Nat Commun 2017 07 3;8(1):53. Epub 2017 Jul 3.

Department of Urology, Boston Children's Hospital, Department of Microbiology and Immunobiology, Department of Surgery, Harvard Medical School, 300 Longwood Avenue, Boston, Massachusetts, 02115, USA.

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http://dx.doi.org/10.1038/s41467-017-00064-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495808PMC
July 2017

The structure of the tetanus toxin reveals pH-mediated domain dynamics.

EMBO Rep 2017 08 23;18(8):1306-1317. Epub 2017 Jun 23.

Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden

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http://dx.doi.org/10.15252/embr.201744198DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538627PMC
August 2017

Glycans Confer Specificity to the Recognition of Ganglioside Receptors by Botulinum Neurotoxin A.

J Am Chem Soc 2017 01 27;139(1):218-230. Epub 2016 Dec 27.

Department of Organic Chemistry, Arrhenius Laboratory, Stockholm University , S-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1021/jacs.6b09534DOI Listing
January 2017

NUDT15 Hydrolyzes 6-Thio-DeoxyGTP to Mediate the Anticancer Efficacy of 6-Thioguanine.

Cancer Res 2016 09 16;76(18):5501-11. Epub 2016 Aug 16.

Science for Life Laboratory, Division of Translational Medicine and Chemical Biology, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1158/0008-5472.CAN-16-0584DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6847052PMC
September 2016

A comparison of X-ray and calculated structures of the enzyme MTH1.

J Mol Model 2016 07 27;22(7):168. Epub 2016 Jun 27.

In Silico Chemical Consulting, 128 Longwood Ave, Lakeway, TX, 78734, USA.

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http://dx.doi.org/10.1007/s00894-016-3025-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923096PMC
July 2016

DNA compaction by the bacteriophage protein Cox studied on the single DNA molecule level using nanofluidic channels.

Nucleic Acids Res 2016 09 29;44(15):7219-27. Epub 2016 Apr 29.

Department of Biology and Biological Engineering, Chalmers University of Technology, SE-41296 Gothenburg, Sweden

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http://dx.doi.org/10.1093/nar/gkw352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009727PMC
September 2016

The C repressor of the P2 bacteriophage.

J Biomol NMR 2016 Feb 22;64(2):175-80. Epub 2015 Dec 22.

Department of Clinical Neurosciences, Karolinska Institute, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s10858-015-9999-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4752584PMC
February 2016

Crystal structure of the bacteriophage P2 integrase catalytic domain.

FEBS Lett 2015 Nov 8;589(23):3556-63. Epub 2015 Oct 8.

Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.febslet.2015.09.026DOI Listing
November 2015

Vinylic MIDA Boronates: New Building Blocks for the Synthesis of Aza-Heterocycles.

Chemistry 2015 May 25;21(20):7394-8. Epub 2015 Mar 25.

Science for Life Laboratory, Division of Translational, Medicine & Chemical Biology, Department of Medical Biochemistry & Biophysics, Karolinska Institutet, Stockholm, 171 21 (Sweden) http://www.helleday.org.

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http://dx.doi.org/10.1002/chem.201406549DOI Listing
May 2015

Structural insight into DNA binding and oligomerization of the multifunctional Cox protein of bacteriophage P2.

Nucleic Acids Res 2014 Feb 19;42(4):2725-35. Epub 2013 Nov 19.

Department of Biochemistry and Biophysics, Arrhenius Laboratories for Natural Sciences, Stockholm University, SE-10691 Stockholm, Sweden and Department of Molecular Biosciences, The Wenner-Gren Institute, Arrhenius Laboratories for Natural Sciences, Stockholm University, SE-10691 Stockholm, Sweden.

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http://dx.doi.org/10.1093/nar/gkt1119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936717PMC
February 2014

Organellar oligopeptidase (OOP) provides a complementary pathway for targeting peptide degradation in mitochondria and chloroplasts.

Proc Natl Acad Sci U S A 2013 Oct 16;110(40):E3761-9. Epub 2013 Sep 16.

Departments of Biochemistry and Biophysics and Neurochemistry, Arrhenius Laboratories for Natural Sciences, Stockholm University, SE-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1073/pnas.1307637110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791733PMC
October 2013

Crystal structures of botulinum neurotoxin DC in complex with its protein receptors synaptotagmin I and II.

Structure 2013 Sep 8;21(9):1602-11. Epub 2013 Aug 8.

Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.str.2013.06.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3803103PMC
September 2013

Structure of dual receptor binding to botulinum neurotoxin B.

Nat Commun 2013 ;4:2058

Department of Biochemistry and Biophysics, Stockholm University, Stockholm 10691, Sweden.

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http://dx.doi.org/10.1038/ncomms3058DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3752466PMC
December 2013

Botulinum neurotoxin D-C uses synaptotagmin I and II as receptors, and human synaptotagmin II is not an effective receptor for type B, D-C and G toxins.

J Cell Sci 2012 Jul 27;125(Pt 13):3233-42. Epub 2012 Mar 27.

Department of Microbiology and Immunobiology, Harvard Medical School and Division of Neuroscience, New England Primate Research Center, Southborough, MA 01772, USA.

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http://dx.doi.org/10.1242/jcs.103564DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067266PMC
July 2012

Inhibition of chlamydial class Ic ribonucleotide reductase by C-terminal peptides from protein R2.

J Pept Sci 2011 Nov 4;17(11):756-62. Epub 2011 Oct 4.

Department of Biochemistry and Biophysics, Stockholm University, Sweden.

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http://dx.doi.org/10.1002/psc.1399DOI Listing
November 2011

Crystal structure of human MTH1 and the 8-oxo-dGMP product complex.

FEBS Lett 2011 Aug 23;585(16):2617-21. Epub 2011 Jul 23.

Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.febslet.2011.07.017DOI Listing
August 2011

Purification, modeling, and analysis of botulinum neurotoxin subtype A5 (BoNT/A5) from Clostridium botulinum strain A661222.

Appl Environ Microbiol 2011 Jun 22;77(12):4217-22. Epub 2011 Apr 22.

Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.

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http://dx.doi.org/10.1128/AEM.00201-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3131645PMC
June 2011

Structural and functional studies of the human phosphoribosyltransferase domain containing protein 1.

FEBS J 2010 Dec 5;277(23):4920-30. Epub 2010 Nov 5.

Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1742-4658.2010.07897.xDOI Listing
December 2010

Crystal structure of the P2 C-repressor: a binder of non-palindromic direct DNA repeats.

Nucleic Acids Res 2010 Nov 17;38(21):7778-90. Epub 2010 Jul 17.

Department of Biochemistry and Biophysics, Center for Biomembrane Research, Stockholm University, SE-106 91 Stockholm, Sweden.

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http://dx.doi.org/10.1093/nar/gkq626DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2995052PMC
November 2010

Structural studies of tri-functional human GART.

Nucleic Acids Res 2010 Nov 14;38(20):7308-19. Epub 2010 Jul 14.

Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-17177 Stockholm, Sweden.

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http://nar.oxfordjournals.org/content/early/2010/07/14/nar.g
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkq595
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http://dx.doi.org/10.1093/nar/gkq595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978367PMC
November 2010

Crystal structure of the botulinum neurotoxin type G binding domain: insight into cell surface binding.

J Mol Biol 2010 Apr 26;397(5):1287-97. Epub 2010 Feb 26.

Department of Molecular Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.jmb.2010.02.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928138PMC
April 2010

The crystal structure of human cleavage and polyadenylation specific factor-5 reveals a dimeric Nudix protein with a conserved catalytic site.

Proteins 2008 Dec;73(4):1047-52

Department of Medical Biochemistry and Biophysics, Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1002/prot.22198DOI Listing
December 2008

Crystal structure of botulinum neurotoxin type A in complex with the cell surface co-receptor GT1b-insight into the toxin-neuron interaction.

PLoS Pathog 2008 Aug 15;4(8):e1000129. Epub 2008 Aug 15.

Department of Molecular Biology, The Scripps Research Institute, La Jolla, California, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1000129DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493045PMC
August 2008

The structure of the PP2A regulatory subunit B56 gamma: the remaining piece of the PP2A jigsaw puzzle.

Proteins 2009 Jan;74(1):212-21

Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden.

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http://dx.doi.org/10.1002/prot.22150DOI Listing
January 2009

The crystal structure of the human toll-like receptor 10 cytoplasmic domain reveals a putative signaling dimer.

J Biol Chem 2008 May 10;283(18):11861-5. Epub 2008 Mar 10.

Structural Genomics Consortium, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1074/jbc.C800001200DOI Listing
May 2008

The crystal structure of the bifunctional deaminase/reductase RibD of the riboflavin biosynthetic pathway in Escherichia coli: implications for the reductive mechanism.

J Mol Biol 2007 Oct 8;373(1):48-64. Epub 2006 Dec 8.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jmb.2006.12.009DOI Listing
October 2007

Crystal structure of human cytosolic 5'-nucleotidase II: insights into allosteric regulation and substrate recognition.

J Biol Chem 2007 Jun 3;282(24):17828-36. Epub 2007 Apr 3.

Department of Biochemistry and Biophysics, Stockholm University, 10691 Stockholm, Sweden.

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http://dx.doi.org/10.1074/jbc.M700917200DOI Listing
June 2007

The structure of human collapsin response mediator protein 2, a regulator of axonal growth.

J Neurochem 2007 May 22;101(4):906-17. Epub 2007 Jan 22.

Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1111/j.1471-4159.2006.04401.xDOI Listing
May 2007

Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T.

J Biol Chem 2007 Feb 29;282(5):3182-7. Epub 2006 Nov 29.

Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institute, 17177 Stockholm, Sweden.

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http://dx.doi.org/10.1074/jbc.M609838200DOI Listing
February 2007

Structures of the hydrolase domain of human 10-formyltetrahydrofolate dehydrogenase and its complex with a substrate analogue.

Acta Crystallogr D Biol Crystallogr 2006 Nov 18;62(Pt 11):1294-9. Epub 2006 Oct 18.

Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-17177 Stockholm, Sweden.

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http://scripts.iucr.org/cgi-bin/paper?S0907444906026849
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http://dx.doi.org/10.1107/S0907444906026849DOI Listing
November 2006

GRETA, a new multifermenter system for structural genomics and process optimization.

Acta Crystallogr D Biol Crystallogr 2006 Oct 19;62(Pt 10):1227-31. Epub 2006 Sep 19.

Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1107/S090744490603441XDOI Listing
October 2006

Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy.

Acta Crystallogr Sect F Struct Biol Cryst Commun 2006 Jul 10;62(Pt 7):613-7. Epub 2006 Jun 10.

Structural Genomics Consortium, Department of Medical Biochemistry and Biophysics, Karolinska Institutet, S-17177 Stockholm, Sweden.

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http://dx.doi.org/10.1107/S1744309106018136DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242944PMC
July 2006

Crystal structure of CaiB, a type-III CoA transferase in carnitine metabolism.

Biochemistry 2004 Nov;43(44):13996-4003

Department of Biochemistry and Biophysics, Stockholm University, Roslagstullsbacken 15, Albanova University Center, SE-10691 Stockholm, Sweden.

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http://dx.doi.org/10.1021/bi048481cDOI Listing
November 2004

The radical site in chlamydial ribonucleotide reductase defines a new R2 subclass.

Science 2004 Jul;305(5681):245-8

Department of Biochemistry and Biophysics, Stockholm University, Roslagstullsbacken 15, Albanova University Center, SE-10691 Stockholm, Sweden.

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http://dx.doi.org/10.1126/science.1098419DOI Listing
July 2004

Crystals of the ribonucleotide reductase R2 protein from Chlamydia trachomatis obtained by heavy-atom co-crystallization.

Acta Crystallogr D Biol Crystallogr 2004 Feb 23;60(Pt 2):376-8. Epub 2004 Jan 23.

Department of Biochemistry and Biophysics, Stockholm University, Roslagstullsbacken 15, Albanova University Center, SE-10691 Stockholm, Sweden.

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http://dx.doi.org/10.1107/S0907444903028208DOI Listing
February 2004

A prokaryotic alternative oxidase present in the bacterium Novosphingobium aromaticivorans.

FEBS Lett 2003 Sep;552(2-3):189-92

Department of Biochemistry and Biophysics, Stockholm University, Roslagstullsbacken 15, Albanova University Center, SE-10691 Stockholm, Sweden.

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http://dx.doi.org/10.1016/s0014-5793(03)00920-7DOI Listing
September 2003

Membrane-bound diiron carboxylate proteins.

Annu Rev Plant Biol 2003 ;54:497-517

Department of Biochemistry and Biophysics, Arrhenius Laboratory for Natural Sciences, Stockholm University, Svante Arrhenius väg 12, SE-106 91 Stockholm, Sweden.

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http://www.annualreviews.org/doi/10.1146/annurev.arplant.54.
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http://dx.doi.org/10.1146/annurev.arplant.54.031902.134915DOI Listing
October 2003

Screening for functional expression and overexpression of a family of diiron-containing interfacial membrane proteins using the univector recombination system.

Protein Sci 2003 Jan;12(1):124-34

Department of Biochemistry and Biophysics, Stockholm University, Svante Arrhenius väg 12, S-106 91 Stockholm, Sweden.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2312407PMC
http://dx.doi.org/10.1110/ps.0223703DOI Listing
January 2003

EPR studies of the mitochondrial alternative oxidase. Evidence for a diiron carboxylate center.

J Biol Chem 2002 Nov 4;277(46):43608-14. Epub 2002 Sep 4.

Department of Biochemistry and Biophysics, Stockholm University Svante Arrhenius väg 16, Sweden.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M206724200
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http://dx.doi.org/10.1074/jbc.M206724200DOI Listing
November 2002