Pak Sham

Pak Sham

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regBase: whole genome base-wise aggregation and functional prediction for human non-coding regulatory variants.

Nucleic Acids Res 2019 Dec;47(21):e134

Department of Pharmacology, School of Basic Medical Sciences, Tianjin Key Laboratory of Inflammation Biology, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China.

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http://dx.doi.org/10.1093/nar/gkz774DOI Listing
December 2019

CAUSALdb: a database for disease/trait causal variants identified using summary statistics of genome-wide association studies.

Nucleic Acids Res 2019 Nov 6. Epub 2019 Nov 6.

2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China.

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http://dx.doi.org/10.1093/nar/gkz1026DOI Listing
November 2019

DESE: estimating driver tissues by selective expression of genes associated with complex diseases or traits.

Genome Biol 2019 11 6;20(1):233. Epub 2019 Nov 6.

Zhongshan School of Medicine, Center for Precision Medicine, Sun Yat-sen University, Guangzhou, 510080, China.

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http://dx.doi.org/10.1186/s13059-019-1801-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6836538PMC
November 2019

Methods and resources to access mutation-dependent effects on cancer drug treatment.

Brief Bioinform 2019 Nov 21. Epub 2019 Nov 21.

Department of Pharmacology, Tianjin Key Laboratory of Inflammation Biology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

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http://dx.doi.org/10.1093/bib/bbz109DOI Listing
November 2019

QTLbase: an integrative resource for quantitative trait loci across multiple human molecular phenotypes.

Nucleic Acids Res 2019 Oct 10. Epub 2019 Oct 10.

Department of Pharmacology, Tianjin Key Laboratory of Inflammation Biology, 2011 Collaborative Innovation Center of Tianjin for Medical Epigenetics, School of Basic Medical Sciences, National Clinical Research Center for Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin 300070, China.

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http://dx.doi.org/10.1093/nar/gkz888DOI Listing
October 2019

Biased cognition in East Asian and Western cultures.

PLoS One 2019 15;14(10):e0223358. Epub 2019 Oct 15.

Department of Experimental Psychology, University of Oxford, Oxford, England, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0223358PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6793946PMC
October 2019

The Maudsley environmental risk score for psychosis.

Psychol Med 2019 Sep 19:1-8. Epub 2019 Sep 19.

Health Service and Population Research, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.

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http://dx.doi.org/10.1017/S0033291719002319DOI Listing
September 2019

Inheritance of Neural Substrates for Motivation and Pleasure.

Psychol Sci 2019 Aug 18;30(8):1205-1217. Epub 2019 Jul 18.

1 Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.

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http://dx.doi.org/10.1177/0956797619859340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794661PMC
August 2019

Ten-year employment patterns of patients with first-episode schizophrenia-spectrum disorders: comparison of early intervention and standard care services.

Br J Psychiatry 2019 Jul 9:1-7. Epub 2019 Jul 9.

Clinical Professor, Department of Psychiatry,Li Ka Shing Faculty of Medicine, and The State Key Laboratory of Brain and Cognitive Sciences,The University of Hong Kong,Hong Kong.

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https://www.cambridge.org/core/product/identifier/S000712501
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http://dx.doi.org/10.1192/bjp.2019.161DOI Listing
July 2019

High risk Epstein-Barr virus variants characterized by distinct polymorphisms in the EBER locus are strongly associated with nasopharyngeal carcinoma.

Int J Cancer 2019 06 7;144(12):3031-3042. Epub 2019 Jan 7.

Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32049
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http://dx.doi.org/10.1002/ijc.32049DOI Listing
June 2019

Next-Generation Sequencing in Human Genetic Studies: Genome Technologies and Applications to Human Genetic Studies.

Hum Hered 2018 9;83(3):105-106. Epub 2019 Jan 9.

Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA.

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https://www.karger.com/Article/FullText/494818
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http://dx.doi.org/10.1159/000494818DOI Listing
June 2019

Commonality in dysregulated expression of gene sets in cortical brains of individuals with autism, schizophrenia, and bipolar disorder.

Transl Psychiatry 2019 05 24;9(1):152. Epub 2019 May 24.

Department of Psychiatry, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1038/s41398-019-0488-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6534650PMC
May 2019

Chemotherapy-Induced Cognitive Impairment Is Associated with Cytokine Dysregulation and Disruptions in Neuroplasticity.

Mol Neurobiol 2019 Mar 14;56(3):2234-2243. Epub 2018 Jul 14.

School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1007/s12035-018-1224-4DOI Listing
March 2019

A powerful conditional gene-based association approach implicated functionally important genes for schizophrenia.

Bioinformatics 2019 02;35(4):628-635

The Centre for Genomic Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1093/bioinformatics/bty682DOI Listing
February 2019

A joint study of whole exome sequencing and structural MRI analysis in major depressive disorder.

Psychol Med 2019 Feb 6:1-12. Epub 2019 Feb 6.

Psychiatric Laboratory and Mental Health Center, The State Key Laboratory of Biotherapy,West China Hospital of Sichuan University,Chengdu, Sichuan,China.

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http://dx.doi.org/10.1017/S0033291719000072DOI Listing
February 2019

Cancer gene mutations in congenital pulmonary airway malformation patients.

ERJ Open Res 2019 Feb 4;5(1). Epub 2019 Feb 4.

Dept of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1183/23120541.00196-2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360213PMC
February 2019

Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders.

World J Stem Cells 2019 Feb;11(2):55-72

Department of Psychiatry, the University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.4252/wjsc.v11.i2.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397804PMC
February 2019

Tractography-based classification in distinguishing patients with first-episode schizophrenia from healthy individuals.

Prog Neuropsychopharmacol Biol Psychiatry 2019 01 20;88:66-73. Epub 2018 Jun 20.

Castle Peak Hospital, Hong Kong, China; Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02785846183000
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http://dx.doi.org/10.1016/j.pnpbp.2018.06.010DOI Listing
January 2019

HIV-1 Tat and methamphetamine co-induced oxidative cellular injury is mitigated by N-acetylcysteine amide (NACA) through rectifying mTOR signaling.

Toxicol Lett 2018 Dec 24;299:159-171. Epub 2018 Sep 24.

CUHK-SDU Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2018.09.009DOI Listing
December 2018

Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events.

Matrix Biol 2018 09 9;70:123-139. Epub 2018 Apr 9.

School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; The University of Hong Kong - Shenzhen Institute of Research and Innovation (HKU-SIRI), Hi-Tech Industrial Park, Nanshan, Shenzhen, China. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.03.024DOI Listing
September 2018

A powerful approach reveals numerous expression quantitative trait haplotypes in multiple tissues.

Bioinformatics 2018 09;34(18):3145-3150

Department of Psychiatry, The Centre for Genomic Sciences, State Key Laboratory of Brain and Cognitive Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1093/bioinformatics/bty318DOI Listing
September 2018

GWAS4D: multidimensional analysis of context-specific regulatory variant for human complex diseases and traits.

Nucleic Acids Res 2018 07;46(W1):W114-W120

Department of Pharmacology, Collaborative Innovation Center of Tianjin for Medical Epigenetics, Tianjin Key Laboratory of Medical Epigenetics, School of Basic Medical Sciences, Tianjin Medical University, Tianjin, China.

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https://academic.oup.com/nar/article/46/W1/W114/4996581
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http://dx.doi.org/10.1093/nar/gky407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6030885PMC
July 2018

Rare variants and de novo variants in mesial temporal lobe epilepsy with hippocampal sclerosis.

Neurol Genet 2018 Jun 11;4(3):e245. Epub 2018 Jun 11.

Centre for Genomic Sciences and Department of Psychiatry (J.K.L.W., H.G., L.B., P.C.S., S.S.C.), Li Ka Shing Faculty of Medicine, The University of Hong Kong; Department of Medicine and Therapeutics (M.K., P.K.), The Chinese University of Hong Kong; Department of Medicine (P.W.N.), United Christian Hospital; Department of Medicine (C.H.T.L.), Queen Elizabeth Hospital, Hong Kong, China; Departments of Medicine and Neurology (P.K.), The University of Melbourne, Royal Melbourne Hospital, Australia; Department of Epidemiology and Preventive Medicine (S.S.C.) and Department of Anatomy and Anthropology (S.S.C.), Sackler Faculty of Medicine, Tel Aviv University, Israel; and The State Key Laboratory of Brain and Cognitive Sciences (P.C.S., S.S.C.).

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http://dx.doi.org/10.1212/NXG.0000000000000245DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999346PMC
June 2018

Long-term effects of discontinuation from antipsychotic maintenance following first-episode schizophrenia and related disorders: a 10 year follow-up of a randomised, double-blind trial.

Lancet Psychiatry 2018 05 15;5(5):432-442. Epub 2018 Mar 15.

Department of Psychiatry, University of Hong Kong, Hong Kong Special Administrative Region, China; State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1016/S2215-0366(18)30090-7DOI Listing
May 2018

Etiology of developmental spinal stenosis: A genome-wide association study.

J Orthop Res 2018 04 17;36(4):1262-1268. Epub 2017 Oct 17.

Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/jor.23746DOI Listing
April 2018

Multifactorial disease risk calculator: Risk prediction for multifactorial disease pedigrees.

Genet Epidemiol 2018 03 26;42(2):130-133. Epub 2017 Nov 26.

Department of Psychiatry and Centre for Genomic Sciences, University of Hong Kong, Hong Kong SAR.

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http://dx.doi.org/10.1002/gepi.22101DOI Listing
March 2018

Actionable secondary findings from whole-genome sequencing of 954 East Asians.

Hum Genet 2018 Jan 11;137(1):31-37. Epub 2017 Nov 11.

Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1007/s00439-017-1852-1DOI Listing
January 2018

Genetic overlap between epilepsy and schizophrenia: Evidence from cross phenotype analysis in Hong Kong Chinese population.

Am J Med Genet B Neuropsychiatr Genet 2018 Jan 17;177(1):86-92. Epub 2017 Nov 17.

Center for Genomic Sciences, The University of Hong Kong, Hong Kong, SAR, China.

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http://dx.doi.org/10.1002/ajmg.b.32607DOI Listing
January 2018

Linnorm: improved statistical analysis for single cell RNA-seq expression data.

Nucleic Acids Res 2017 Dec;45(22):e179

Department of Health Sciences Research and Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1093/nar/gkx828DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5727406PMC
December 2017

Corrigendum: Linnorm: improved statistical analysis for single cell RNA-seq expression data.

Nucleic Acids Res 2017 12;45(22):13097

Department of Health Sciences Research and Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1093/nar/gkx1189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728397PMC
December 2017

Polygenic scores via penalized regression on summary statistics.

Genet Epidemiol 2017 09 8;41(6):469-480. Epub 2017 May 8.

Centre for Genomic Sciences, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1002/gepi.22050DOI Listing
September 2017

Sharing of Genes and Pathways Across Complex Phenotypes: A Multilevel Genome-Wide Analysis.

Genetics 2017 07 11;206(3):1601-1609. Epub 2017 May 11.

Center for Genomic Sciences, University of Hong Kong, Hong Kong SAR, China

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http://dx.doi.org/10.1534/genetics.116.198150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500153PMC
July 2017

Selecting cases and controls for DNA sequencing studies using family histories of disease.

Stat Med 2017 06 21;36(13):2081-2099. Epub 2017 Feb 21.

Interdisciplinary Program of Bioinformatics, Seoul National University, Seoul, Korea.

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http://dx.doi.org/10.1002/sim.7248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810411PMC
June 2017

Exploring genetic associations with ceRNA regulation in the human genome.

Nucleic Acids Res 2017 Jun;45(10):5653-5665

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard T.H.Chan School of Public Health, Boston, MA 02215, USA.

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http://dx.doi.org/10.1093/nar/gkx331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449616PMC
June 2017

Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits.

Bioinformatics 2017 03;33(6):886-892

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://dx.doi.org/10.1093/bioinformatics/btw745DOI Listing
March 2017

Improving polygenic risk prediction from summary statistics by an empirical Bayes approach.

Sci Rep 2017 02 1;7:41262. Epub 2017 Feb 1.

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://www.nature.com/articles/srep41262
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http://dx.doi.org/10.1038/srep41262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286518PMC
February 2017

founder mutation causes protein trafficking defects in Chinese patients with cystic fibrosis.

Mol Genet Genomic Med 2017 Jan 13;5(1):40-49. Epub 2016 Nov 13.

Department of Paediatrics and Adolescent MedicineLKS Faculty of MedicineThe University of Hong KongHong KongHong Kong; Department of Paediatrics and Adolescent MedicineQueen Mary HospitalHong KongHong Kong; Department of Paediatrics and Adolescent MedicineThe Duchess of Kent Children's Hospital at Sandy BayHong Kong.

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http://dx.doi.org/10.1002/mgg3.258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241212PMC
January 2017

A fast and powerful W-test for pairwise epistasis testing.

Nucleic Acids Res 2016 12 26;44(21):10526. Epub 2016 Sep 26.

Division of Biostatistics and Centre for Clinical Research and Biostatistics, JC School of Public Health and Primary Care, the Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China.

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http://dx.doi.org/10.1093/nar/gkw866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137446PMC
December 2016

Sacral agenesis: a pilot whole exome sequencing and copy number study.

BMC Med Genet 2016 Dec 22;17(1):98. Epub 2016 Dec 22.

Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong SAR.

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http://dx.doi.org/10.1186/s12881-016-0359-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178083PMC
December 2016

A single low dose of valproic acid in late prenatal life alters postnatal behavior and glutamic acid decarboxylase levels in the mouse.

Behav Brain Res 2016 11 4;314:190-8. Epub 2016 Aug 4.

Department of Forensic and Neurodevelopmental Science, The Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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http://dx.doi.org/10.1016/j.bbr.2016.08.006DOI Listing
November 2016

Amelioration of X-Linked Related Autophagy Failure in Danon Disease With DNA Methylation Inhibitor.

Circulation 2016 Nov 27;134(18):1373-1389. Epub 2016 Sep 27.

From Cardiology Division, Department of Medicine (K.-M.N., J.C.Y.H., Y.-K.L., W.-H.L., K.-W.A., Y.-M.L., L.-Y.W., C.-W.S., H.-F.T.) and Department of Psychiatry (A.W.B., S.-W.C., P.C.S., A.C.), Queen Mary Hospital, Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine (K.-M.N, C.W.-S., H.-F.T.), Hong Kong-Guangdong Joint Laboratory on Stem Cell and Regenerative Medicine (M.A.E., H.-F.T.), Centre for Genomic Sciences, Li Ka Shing Faculty of Medicine (P.C.S.), State Key Laboratory for Cognitive and Brain Sciences, Li Ka Shing Faculty of Medicine (P.C.S.), and Shenzhen Institutes of Research and Innovation (H.-F.T.), University of Hong Kong, Hong Kong SAR, China; Stem Cell Disease Models, A*STAR Institute of Medical Biology, Singapore (P.Y.M.); MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK (A.W.B.); and Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Guangzhou, China (M.A.E.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019847DOI Listing
November 2016

Inheritance-mode specific pathogenicity prioritization (ISPP) for human protein coding genes.

Bioinformatics 2016 10 26;32(20):3065-3071. Epub 2016 Jun 26.

Department of Psychiatry Centre for Genomics Science, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1093/bioinformatics/btw381DOI Listing
October 2016

Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study.

Spine J 2016 09 5;16(9):1079-89. Epub 2016 May 5.

Centre for Genomic Sciences, The University of Hong Kong, 5 Sassoon Rd, Pokfulam, Hong Kong SAR, China; Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.spinee.2016.04.020DOI Listing
September 2016

Predicting regulatory variants with composite statistic.

Bioinformatics 2016 09 6;32(18):2729-36. Epub 2016 Jun 6.

Centre for Genomic Sciences, Department of Health Sciences Research, Center for Individualized Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA and Department of Biomedical Informatics, Arizona State University, Scottsdale, AZ 85259, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw288DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6280872PMC
September 2016

Association of BDNF Polymorphisms with the Risk of Epilepsy: a Multicenter Study.

Mol Neurobiol 2016 07 16;53(5):2869-2877. Epub 2015 Apr 16.

Pharmacogenomics Laboratory, Department of Pharmacology, Faculty of Medicine, University of Malaya, Lembah Pantai, 59100, Kuala Lumpur, Malaysia.

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http://dx.doi.org/10.1007/s12035-015-9150-1DOI Listing
July 2016

Local True Discovery Rate Weighted Polygenic Scores Using GWAS Summary Data.

Behav Genet 2016 07 9;46(4):573-82. Epub 2016 Jan 9.

Centre for Genomic Sciences, University of Hong Kong, 5 Sassoon Road, Hong Kong, China.

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http://dx.doi.org/10.1007/s10519-015-9770-2DOI Listing
July 2016

Longitudinal heritability of childhood aggression.

Am J Med Genet B Neuropsychiatr Genet 2016 07 19;171(5):697-707. Epub 2016 Jan 19.

Department of Biological Psychology, Netherlands Twin Register, VU University Amsterdam, The Netherlands.

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http://dx.doi.org/10.1002/ajmg.b.32420DOI Listing
July 2016

Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice.

Behav Genet 2016 07 29;46(4):529-37. Epub 2016 Jan 29.

Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK.

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http://dx.doi.org/10.1007/s10519-015-9777-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886156PMC
July 2016

A fast and powerful W-test for pairwise epistasis testing.

Nucleic Acids Res 2016 07 25;44(12):e115. Epub 2016 Apr 25.

Division of Biostatistics and Centre for Clinical Research and Biostatistics, JC School of Public Health and Primary Care, the Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China CUHK Shenzhen Research Institute, Shenzhen, China.

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http://dx.doi.org/10.1093/nar/gkw347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4937324PMC
July 2016

The Effect of Oxytocin on Social and Non-Social Behaviour and Striatal Protein Expression in C57BL/6N Mice.

PLoS One 2015 30;10(12):e0145638. Epub 2015 Dec 30.

Department of Forensic and Neurodevelopmental Sciences, The Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0145638PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696826PMC
June 2016

FAPI: Fast and accurate P-value Imputation for genome-wide association study.

Eur J Hum Genet 2016 May 26;24(5):761-6. Epub 2015 Aug 26.

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://dx.doi.org/10.1038/ejhg.2015.190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930094PMC
May 2016

Whole-exome sequencing identifies MST1R as a genetic susceptibility gene in nasopharyngeal carcinoma.

Proc Natl Acad Sci U S A 2016 Mar 7;113(12):3317-22. Epub 2016 Mar 7.

Department of Clinical Oncology, University of Hong Kong, Hong Kong (Special Administrative Region), People's Republic of China; Center for Nasopharyngeal Carcinoma Research, University of Hong Kong, Hong Kong (Special Administrative Region), People's Republic of China;

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http://dx.doi.org/10.1073/pnas.1523436113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812767PMC
March 2016

Psychiatric genetics in China: achievements and challenges.

Mol Psychiatry 2016 Jan 20;21(1):4-9. Epub 2015 Oct 20.

Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.

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http://dx.doi.org/10.1038/mp.2015.95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830695PMC
January 2016

GWASdb v2: an update database for human genetic variants identified by genome-wide association studies.

Nucleic Acids Res 2016 Jan 28;44(D1):D869-76. Epub 2015 Nov 28.

Centre for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China School of Biomedical Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China

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http://dx.doi.org/10.1093/nar/gkv1317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702921PMC
January 2016

SNPTracker: A Swift Tool for Comprehensive Tracking and Unifying dbSNP rs IDs and Genomic Coordinates of Massive Sequence Variants.

G3 (Bethesda) 2015 Nov 19;6(1):205-7. Epub 2015 Nov 19.

Department of Psychiatry, University of Hong Kong Centre for Genomic Sciences, University of Hong Kong State Key Laboratory for Cognitive and Brain Sciences, University of Hong Kong Center for Reproduction, Development and Growth, University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1534/g3.115.021832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704719PMC
November 2015

The Effect of Paternal Age on Relapse in First-Episode Schizophrenia.

Can J Psychiatry 2015 Aug;60(8):346-53

Professor, Department of Psychiatry, University of Hong Kong, Hong Kong Special Administrative Region, China; Professor, State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://journals.sagepub.com/doi/10.1177/070674371506000803
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542514PMC
http://dx.doi.org/10.1177/070674371506000803DOI Listing
August 2015

SPS: A Simulation Tool for Calculating Power of Set-Based Genetic Association Tests.

Genet Epidemiol 2015 Jul 21;39(5):395-7. Epub 2015 May 21.

Department of Psychiatry, the University of Hong Kong, Pokfulam, Hong Kong.

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http://doi.wiley.com/10.1002/gepi.21898
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http://dx.doi.org/10.1002/gepi.21898DOI Listing
July 2015

wKGGSeq: A Comprehensive Strategy-Based and Disease-Targeted Online Framework to Facilitate Exome Sequencing Studies of Inherited Disorders.

Hum Mutat 2015 May 4;36(5):496-503. Epub 2015 Apr 4.

Centre for Genomic Sciences, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China; Departments of Biochemistry, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China; Shenzhen Institute of Research and Innovation, The University of Hong Kong, Shenzhen, Guangdong, 518057, China.

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http://dx.doi.org/10.1002/humu.22766DOI Listing
May 2015

HaploShare: identification of extended haplotypes shared by cases and evaluation against controls.

Genome Biol 2015 May 9;16:92. Epub 2015 May 9.

Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Rd., Pokfulam, Hong Kong.

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http://dx.doi.org/10.1186/s13059-015-0662-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4432975PMC
May 2015

PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling.

Int J Biochem Cell Biol 2015 Apr 11;61:53-62. Epub 2015 Feb 11.

Department of Biochemistry, University of Hong Kong, 21 Sassoon Road, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2015.02.003DOI Listing
April 2015

HLAreporter: a tool for HLA typing from next generation sequencing data.

Genome Med 2015 16;7(1):25. Epub 2015 Mar 16.

Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, Hong Kong.

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http://dx.doi.org/10.1186/s13073-015-0145-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4407542PMC
April 2015

Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9).

Sci Rep 2015 Feb 17;5:8517. Epub 2015 Feb 17.

1] State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University [2] Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Hangzhou, China.

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http://www.nature.com/articles/srep08517
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http://dx.doi.org/10.1038/srep08517DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649671PMC
February 2015