Pak C Sham

Pak C Sham

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Inheritance of Neural Substrates for Motivation and Pleasure.

Psychol Sci 2019 Aug 18;30(8):1205-1217. Epub 2019 Jul 18.

1 Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.

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http://dx.doi.org/10.1177/0956797619859340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794661PMC
August 2019

High risk Epstein-Barr virus variants characterized by distinct polymorphisms in the EBER locus are strongly associated with nasopharyngeal carcinoma.

Int J Cancer 2019 06 7;144(12):3031-3042. Epub 2019 Jan 7.

Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32049
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http://dx.doi.org/10.1002/ijc.32049DOI Listing
June 2019

Rational use of mesenchymal stem cells in the treatment of autism spectrum disorders.

World J Stem Cells 2019 Feb;11(2):55-72

Department of Psychiatry, the University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.4252/wjsc.v11.i2.55DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397804PMC
February 2019

Tractography-based classification in distinguishing patients with first-episode schizophrenia from healthy individuals.

Prog Neuropsychopharmacol Biol Psychiatry 2019 01 20;88:66-73. Epub 2018 Jun 20.

Castle Peak Hospital, Hong Kong, China; Neuropsychology and Applied Cognitive Neuroscience Laboratory, CAS Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences, Beijing, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S02785846183000
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http://dx.doi.org/10.1016/j.pnpbp.2018.06.010DOI Listing
January 2019

HIV-1 Tat and methamphetamine co-induced oxidative cellular injury is mitigated by N-acetylcysteine amide (NACA) through rectifying mTOR signaling.

Toxicol Lett 2018 Dec 24;299:159-171. Epub 2018 Sep 24.

CUHK-SDU Joint Laboratory on Reproductive Genetics, School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China. Electronic address:

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http://dx.doi.org/10.1016/j.toxlet.2018.09.009DOI Listing
December 2018

Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events.

Matrix Biol 2018 09 9;70:123-139. Epub 2018 Apr 9.

School of Biomedical Sciences, The University of Hong Kong, Pokfulam, Hong Kong SAR, China; The University of Hong Kong - Shenzhen Institute of Research and Innovation (HKU-SIRI), Hi-Tech Industrial Park, Nanshan, Shenzhen, China. Electronic address:

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http://dx.doi.org/10.1016/j.matbio.2018.03.024DOI Listing
September 2018

Multifactorial disease risk calculator: Risk prediction for multifactorial disease pedigrees.

Genet Epidemiol 2018 03 26;42(2):130-133. Epub 2017 Nov 26.

Department of Psychiatry and Centre for Genomic Sciences, University of Hong Kong, Hong Kong SAR.

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http://dx.doi.org/10.1002/gepi.22101DOI Listing
March 2018

Actionable secondary findings from whole-genome sequencing of 954 East Asians.

Hum Genet 2018 Jan 11;137(1):31-37. Epub 2017 Nov 11.

Division of Paediatric Surgery, Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1007/s00439-017-1852-1DOI Listing
January 2018

Genetic overlap between epilepsy and schizophrenia: Evidence from cross phenotype analysis in Hong Kong Chinese population.

Am J Med Genet B Neuropsychiatr Genet 2018 Jan 17;177(1):86-92. Epub 2017 Nov 17.

Center for Genomic Sciences, The University of Hong Kong, Hong Kong, SAR, China.

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http://dx.doi.org/10.1002/ajmg.b.32607DOI Listing
January 2018

Sharing of Genes and Pathways Across Complex Phenotypes: A Multilevel Genome-Wide Analysis.

Genetics 2017 07 11;206(3):1601-1609. Epub 2017 May 11.

Center for Genomic Sciences, University of Hong Kong, Hong Kong SAR, China

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http://dx.doi.org/10.1534/genetics.116.198150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500153PMC
July 2017

Exploring the predictive power of polygenic scores derived from genome-wide association studies: a study of 10 complex traits.

Bioinformatics 2017 03;33(6):886-892

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://dx.doi.org/10.1093/bioinformatics/btw745DOI Listing
March 2017

Improving polygenic risk prediction from summary statistics by an empirical Bayes approach.

Sci Rep 2017 02 1;7:41262. Epub 2017 Feb 1.

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://www.nature.com/articles/srep41262
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http://dx.doi.org/10.1038/srep41262DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5286518PMC
February 2017

founder mutation causes protein trafficking defects in Chinese patients with cystic fibrosis.

Mol Genet Genomic Med 2017 Jan 13;5(1):40-49. Epub 2016 Nov 13.

Department of Paediatrics and Adolescent MedicineLKS Faculty of MedicineThe University of Hong KongHong KongHong Kong; Department of Paediatrics and Adolescent MedicineQueen Mary HospitalHong KongHong Kong; Department of Paediatrics and Adolescent MedicineThe Duchess of Kent Children's Hospital at Sandy BayHong Kong.

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http://dx.doi.org/10.1002/mgg3.258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241212PMC
January 2017

Sacral agenesis: a pilot whole exome sequencing and copy number study.

BMC Med Genet 2016 Dec 22;17(1):98. Epub 2016 Dec 22.

Department of Psychiatry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, Hong Kong SAR.

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http://dx.doi.org/10.1186/s12881-016-0359-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5178083PMC
December 2016

Amelioration of X-Linked Related Autophagy Failure in Danon Disease With DNA Methylation Inhibitor.

Circulation 2016 Nov 27;134(18):1373-1389. Epub 2016 Sep 27.

From Cardiology Division, Department of Medicine (K.-M.N., J.C.Y.H., Y.-K.L., W.-H.L., K.-W.A., Y.-M.L., L.-Y.W., C.-W.S., H.-F.T.) and Department of Psychiatry (A.W.B., S.-W.C., P.C.S., A.C.), Queen Mary Hospital, Research Center of Heart, Brain, Hormone and Healthy Aging, Li Ka Shing Faculty of Medicine (K.-M.N, C.W.-S., H.-F.T.), Hong Kong-Guangdong Joint Laboratory on Stem Cell and Regenerative Medicine (M.A.E., H.-F.T.), Centre for Genomic Sciences, Li Ka Shing Faculty of Medicine (P.C.S.), State Key Laboratory for Cognitive and Brain Sciences, Li Ka Shing Faculty of Medicine (P.C.S.), and Shenzhen Institutes of Research and Innovation (H.-F.T.), University of Hong Kong, Hong Kong SAR, China; Stem Cell Disease Models, A*STAR Institute of Medical Biology, Singapore (P.Y.M.); MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King's College London, London, UK (A.W.B.); and Key Laboratory of Regenerative Biology of the Chinese Academy of Sciences and Guangdong Provincial Key Laboratory of Stem Cells and Regenerative Medicine, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Guangzhou, China (M.A.E.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.115.019847DOI Listing
November 2016

Two subtypes of intervertebral disc degeneration distinguished by large-scale population-based study.

Spine J 2016 09 5;16(9):1079-89. Epub 2016 May 5.

Centre for Genomic Sciences, The University of Hong Kong, 5 Sassoon Rd, Pokfulam, Hong Kong SAR, China; Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong SAR, China. Electronic address:

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http://dx.doi.org/10.1016/j.spinee.2016.04.020DOI Listing
September 2016

Tspyl2 Loss-of-Function Causes Neurodevelopmental Brain and Behavior Abnormalities in Mice.

Behav Genet 2016 07 29;46(4):529-37. Epub 2016 Jan 29.

Department of Forensic and Neurodevelopmental Science, Institute of Psychiatry, Psychology and Neuroscience, King's College, London, UK.

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http://dx.doi.org/10.1007/s10519-015-9777-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4886156PMC
July 2016

FAPI: Fast and accurate P-value Imputation for genome-wide association study.

Eur J Hum Genet 2016 May 26;24(5):761-6. Epub 2015 Aug 26.

Department of Psychiatry, University of Hong Kong, PokFuLam, Hong Kong.

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http://dx.doi.org/10.1038/ejhg.2015.190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930094PMC
May 2016

SNPTracker: A Swift Tool for Comprehensive Tracking and Unifying dbSNP rs IDs and Genomic Coordinates of Massive Sequence Variants.

G3 (Bethesda) 2015 Nov 19;6(1):205-7. Epub 2015 Nov 19.

Department of Psychiatry, University of Hong Kong Centre for Genomic Sciences, University of Hong Kong State Key Laboratory for Cognitive and Brain Sciences, University of Hong Kong Center for Reproduction, Development and Growth, University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1534/g3.115.021832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704719PMC
November 2015

Cost effective assay choice for rare disease study designs.

Orphanet J Rare Dis 2015 Feb 4;10:10. Epub 2015 Feb 4.

Department of Surgery, University of Hong Kong, Hong Kong, SAR, China.

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http://dx.doi.org/10.1186/s13023-015-0226-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4334400PMC
February 2015

Oncogenic mutation profiling in new lung cancer and mesothelioma cell lines.

Onco Targets Ther 2015 16;8:195-209. Epub 2015 Jan 16.

Department of Anatomy, University of Hong Kong, Hong Kong SAR, People's Republic of China.

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http://dx.doi.org/10.2147/OTT.S71242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303463PMC
February 2015

Early intervention and evaluation for adult-onset psychosis: the JCEP study rationale and design.

Early Interv Psychiatry 2014 Aug 28;8(3):261-8. Epub 2013 Feb 28.

Departments of Psychiatry, University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1111/eip.12034DOI Listing
August 2014

Adiponectin gene variants and the risk of coronary heart disease: a 16-year longitudinal study.

Eur J Endocrinol 2014 Jul 23;171(1):107-15. Epub 2014 Apr 23.

Department of MedicineDepartment of PsychiatryResearch Centre of HeartBrain, Hormone and Healthy AgingLi Ka Shing Faculty of MedicineCentre for Genomic Sciences, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, Hong KongCentre for Vascular ResearchUniversity of New South Wales, Sydney, New South Wales 2052, AustraliaDepartment of MedicineNorthwest Academic Centre, Western Hospital, The University of Melbourne, Melbourne, Victoria, AustraliaDepartment of MedicineDepartment of PsychiatryResearch Centre of HeartBrain, Hormone and Healthy AgingLi Ka Shing Faculty of MedicineCentre for Genomic Sciences, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, Hong KongCentre for Vascular ResearchUniversity of New South Wales, Sydney, New South Wales 2052, AustraliaDepartment of MedicineNorthwest Academic Centre, Western Hospital, The University of Melbourne, Melbourne, Victoria, Australia

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http://dx.doi.org/10.1530/EJE-14-0079DOI Listing
July 2014

Identifying gene-environment interactions in schizophrenia: contemporary challenges for integrated, large-scale investigations.

Authors:
Jim van Os Bart P Rutten Inez Myin-Germeys Philippe Delespaul Wolfgang Viechtbauer Catherine van Zelst Richard Bruggeman Ulrich Reininghaus Craig Morgan Robin M Murray Marta Di Forti Philip McGuire Lucia R Valmaggia Matthew J Kempton Charlotte Gayer-Anderson Kathryn Hubbard Stephanie Beards Simona A Stilo Adanna Onyejiaka Francois Bourque Gemma Modinos Stefania Tognin Maria Calem Michael C O'Donovan Michael J Owen Peter Holmans Nigel Williams Nicholas Craddock Alexander Richards Isla Humphreys Andreas Meyer-Lindenberg F Markus Leweke Heike Tost Ceren Akdeniz Cathrin Rohleder J Malte Bumb Emanuel Schwarz Köksal Alptekin Alp Üçok Meram Can Saka E Cem Atbaşoğlu Sinan Gülöksüz Guvem Gumus-Akay Burçin Cihan Hasan Karadağ Haldan Soygür Eylem Şahin Cankurtaran Semra Ulusoy Berna Akdede Tolga Binbay Ahmet Ayer Handan Noyan Gülşah Karadayı Elçin Akturan Halis Ulaş Celso Arango Mara Parellada Miguel Bernardo Julio Sanjuán Julio Bobes Manuel Arrojo Jose Luis Santos Pedro Cuadrado José Juan Rodríguez Solano Angel Carracedo Enrique García Bernardo Laura Roldán Gonzalo López Bibiana Cabrera Sabrina Cruz Eva Ma Díaz Mesa María Pouso Estela Jiménez Teresa Sánchez Marta Rapado Emiliano González Covadonga Martínez Emilio Sánchez Ma Soledad Olmeda Lieuwe de Haan Eva Velthorst Mark van der Gaag Jean-Paul Selten Daniella van Dam Elsje van der Ven Floor van der Meer Elles Messchaert Tamar Kraan Nadine Burger Marion Leboyer Andrei Szoke Franck Schürhoff Pierre-Michel Llorca Stéphane Jamain Andrea Tortelli Flora Frijda Jeanne Vilain Anne-Marie Galliot Grégoire Baudin Aziz Ferchiou Jean-Romain Richard Ewa Bulzacka Thomas Charpeaud Anne-Marie Tronche Marc De Hert Ruud van Winkel Jeroen Decoster Catherine Derom Evert Thiery Nikos C Stefanis Gabriele Sachs Harald Aschauer Iris Lasser Bernadette Winklbaur Monika Schlögelhofer Anita Riecher-Rössler Stefan Borgwardt Anna Walter Fabienne Harrisberger Renata Smieskova Charlotte Rapp Sarah Ittig Fabienne Soguel-dit-Piquard Erich Studerus Joachim Klosterkötter Stephan Ruhrmann Julia Paruch Dominika Julkowski Desiree Hilboll Pak C Sham Stacey S Cherny Eric Y H Chen Desmond D Campbell Miaoxin Li Carlos María Romeo-Casabona Aitziber Emaldi Cirión Asier Urruela Mora Peter Jones James Kirkbride Mary Cannon Dan Rujescu Ilaria Tarricone Domenico Berardi Elena Bonora Marco Seri Thomas Marcacci Luigi Chiri Federico Chierzi Viviana Storbini Mauro Braca Maria Gabriella Minenna Ivonne Donegani Angelo Fioritti Daniele La Barbera Caterina Erika La Cascia Alice Mulè Lucia Sideli Rachele Sartorio Laura Ferraro Giada Tripoli Fabio Seminerio Anna Maria Marinaro Patrick McGorry Barnaby Nelson G Paul Amminger Christos Pantelis Paulo R Menezes Cristina M Del-Ben Silvia H Gallo Tenan Rosana Shuhama Mirella Ruggeri Sarah Tosato Antonio Lasalvia Chiara Bonetto Elisa Ira Merete Nordentoft Marie-Odile Krebs Neus Barrantes-Vidal Paula Cristóbal Thomas R Kwapil Elisa Brietzke Rodrigo A Bressan Ary Gadelha Nadja P Maric Sanja Andric Marina Mihaljevic Tijana Mirjanic

Schizophr Bull 2014 Jul 24;40(4):729-36. Epub 2014 May 24.

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http://dx.doi.org/10.1093/schbul/sbu069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4059449PMC
July 2014

Impulsivity, cognitive function, and their relationship in heroin-dependent individuals.

J Clin Exp Neuropsychol 2013 17;35(9):897-905. Epub 2013 Sep 17.

a The Research Center of Psychology & Brain Science , Guangzhou University , Guangzhou , China.

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http://dx.doi.org/10.1080/13803395.2013.828022DOI Listing
June 2014

Statistical power and significance testing in large-scale genetic studies.

Nat Rev Genet 2014 May;15(5):335-46

1] Center for Statistical Genetics, Icahn School of Medicine at Mount Sinai, New York 10029-6574, USA. [2] Center for Human Genetic Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA.

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http://dx.doi.org/10.1038/nrg3706DOI Listing
May 2014

Genetic analysis of recently identified osteoporosis susceptibility genes in southern Chinese.

J Clin Endocrinol Metab 2013 Nov 26;98(11):E1827-34. Epub 2013 Jul 26.

MD, Department of Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1210/jc.2013-1055DOI Listing
November 2013

Molecular genetic gene-environment studies using candidate genes in schizophrenia: a systematic review.

Schizophr Res 2013 Nov 2;150(2-3):356-65. Epub 2013 Oct 2.

Department of Psychosis Studies, Institute of Psychiatry, King's College London, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09209964130050
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http://dx.doi.org/10.1016/j.schres.2013.09.010DOI Listing
November 2013

Predicting mendelian disease-causing non-synonymous single nucleotide variants in exome sequencing studies.

PLoS Genet 2013 17;9(1):e1003143. Epub 2013 Jan 17.

Department of Psychiatry, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China.

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http://dx.plos.org/10.1371/journal.pgen.1003143
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http://dx.doi.org/10.1371/journal.pgen.1003143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3547823PMC
May 2013

RET and NRG1 interplay in Hirschsprung disease.

Hum Genet 2013 May 12;132(5):591-600. Epub 2013 Feb 12.

Department of Psychiatry, The University of Hong Kong, Hong Kong SAR, China.

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http://dx.doi.org/10.1007/s00439-013-1272-9DOI Listing
May 2013

Heritability of hallucinations in adolescent twins.

Psychiatry Res 2012 Sep 10;199(2):98-101. Epub 2012 May 10.

Industry-Academics Cooperation, Mokpo National University, Jeonnam, South Korea.

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http://dx.doi.org/10.1016/j.psychres.2012.04.024DOI Listing
September 2012

A comprehensive framework for prioritizing variants in exome sequencing studies of Mendelian diseases.

Nucleic Acids Res 2012 Apr 12;40(7):e53. Epub 2012 Jan 12.

Department of Psychiatry, University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1093/nar/gkr1257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3326332PMC
April 2012

Common polymorphisms in the SERPINI2 gene are associated with refractive error in the 1958 British Birth Cohort.

Invest Ophthalmol Vis Sci 2012 Jan 25;53(1):440-7. Epub 2012 Jan 25.

MRC Centre of Epidemiology for Child Health, Institute of Child Health, University College London, London, United Kingdom.

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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.1
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http://dx.doi.org/10.1167/iovs.10-5640DOI Listing
January 2012

Comparisons of seven algorithms for pathway analysis using the WTCCC Crohn's Disease dataset.

BMC Res Notes 2011 Oct 7;4:386. Epub 2011 Oct 7.

Department of Psychiatry, The University of Hong Kong, Hong Kong, SAR, China.

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http://dx.doi.org/10.1186/1756-0500-4-386DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199264PMC
October 2011

Robust association tests under different genetic models, allowing for binary or quantitative traits and covariates.

Behav Genet 2011 Sep 9;41(5):768-75. Epub 2011 Feb 9.

Department of Psychiatry, 10/F Laboratory Block, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://link.springer.com/10.1007/s10519-011-9450-9
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http://dx.doi.org/10.1007/s10519-011-9450-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162964PMC
September 2011

Uncovering the total heritability explained by all true susceptibility variants in a genome-wide association study.

Genet Epidemiol 2011 Sep 26;35(6):447-56. Epub 2011 May 26.

Department of Psychiatry, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/gepi.20593DOI Listing
September 2011

A simple bias correction in linear regression for quantitative trait association under two-tail extreme selection.

Behav Genet 2011 Sep 29;41(5):776-9. Epub 2011 May 29.

Department of Psychiatry, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1007/s10519-011-9475-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3162965PMC
September 2011

Heritability of serum osteoprotegerin.

Ann Hum Genet 2011 Sep 18;75(5):584-8. Epub 2011 Jul 18.

Department of Psychiatry, the University of Hong Kong, China.

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http://dx.doi.org/10.1111/j.1469-1809.2011.00661.xDOI Listing
September 2011

Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: a potential databank from china.

Front Hum Neurosci 2010 28;4:207. Epub 2010 Oct 28.

Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences Beijing, China.

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http://dx.doi.org/10.3389/fnhum.2010.00207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987619PMC
July 2011

Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases.

Genet Epidemiol 2011 Jul 3;35(5):310-7. Epub 2011 Mar 3.

Department of Psychiatry, University of Hong Kong, Hong Kong SAR, China.

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http://doi.wiley.com/10.1002/gepi.20579
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http://dx.doi.org/10.1002/gepi.20579DOI Listing
July 2011

Genetic variants associated with persistent central obesity and the metabolic syndrome in a 12-year longitudinal study.

Eur J Endocrinol 2011 Mar 8;164(3):381-8. Epub 2010 Dec 8.

Department of Medicine, LKS Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, SAR, China.

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http://dx.doi.org/10.1530/EJE-10-0902DOI Listing
March 2011

GATES: a rapid and powerful gene-based association test using extended Simes procedure.

Am J Hum Genet 2011 Mar;88(3):283-93

Department of Psychiatry and State Key Laboratory for Cognitive and Brain Sciences, the University of Hong Kong, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1016/j.ajhg.2011.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059433PMC
March 2011

Effect size measures in genetic association studies and age-conditional risk prediction.

Hum Hered 2010 13;70(3):205-18. Epub 2010 Sep 13.

Department of Psychiatry, University of Hong Kong, Hong Kong, SAR, China.

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https://www.karger.com/Article/FullText/319192
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http://dx.doi.org/10.1159/000319192DOI Listing
January 2011

Multiple testing and power calculations in genetic association studies.

Cold Spring Harb Protoc 2011 Jan 1;2011(1):pdb.top95. Epub 2011 Jan 1.

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http://dx.doi.org/10.1101/pdb.top95DOI Listing
January 2011

A unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.

PLoS Genet 2010 Dec 2;6(12):e1001230. Epub 2010 Dec 2.

Department of Psychiatry, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1371/journal.pgen.1001230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2996330PMC
December 2010

Haplotype analysis reveals a possible founder effect of RET mutation R114H for Hirschsprung's disease in the Chinese population.

PLoS One 2010 Jun 2;5(6):e10918. Epub 2010 Jun 2.

Paediatric Surgery Division, Department of Surgery, Li Ka Shing Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong, Special Administrative Region, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0010918PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880000PMC
June 2010

Commingling analyses of central corneal thickness and adjusted intraocular pressure in an older Australian population.

Invest Ophthalmol Vis Sci 2010 May 13;51(5):2512-8. Epub 2010 Jan 13.

UCL Institute of Ophthalmology, University College, London, United Kingdom.

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http://dx.doi.org/10.1167/iovs.09-4270DOI Listing
May 2010

SKM-SNP: SNP markers detection method.

J Biomed Inform 2010 Apr 17;43(2):233-9. Epub 2009 Nov 17.

Department of Mathematics, Hong Kong Baptist University, Kowloon Tong, Hong Kong.

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http://dx.doi.org/10.1016/j.jbi.2009.11.004DOI Listing
April 2010

Software for generating liability distributions for pedigrees conditional on their observed disease states and covariates.

Genet Epidemiol 2010 Feb;34(2):159-70

Department of Biostatistics, Institute of Psychiatry, King's College London, United Kingdom.

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http://dx.doi.org/10.1002/gepi.20446DOI Listing
February 2010

Excellent school performance at age 16 and risk of adult bipolar disorder: national cohort study.

Br J Psychiatry 2010 Feb;196(2):109-15

Department of Psychiatry, Institute of Psychiatry, King's College London, London SE5 8AF, UK.

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http://dx.doi.org/10.1192/bjp.bp.108.060368DOI Listing
February 2010

A neurochemical approach to valuation sensitivity over gains and losses.

Proc Biol Sci 2009 Dec 2;276(1676):4181-8. Epub 2009 Sep 2.

Center for Experimental Business Research and Department of Economics, Hong Kong University of Science and Technology, Hong Kong.

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http://dx.doi.org/10.1098/rspb.2009.1312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821348PMC
December 2009

Major genetic effects in glaucoma: commingling analysis of optic disc parameters in an older Australian population.

Invest Ophthalmol Vis Sci 2009 Nov 20;50(11):5275-80. Epub 2009 May 20.

Glaucoma Service, Moorfields Eye Hospital, London, United Kingdom.

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http://dx.doi.org/10.1167/iovs.08-3065DOI Listing
November 2009

A naturalistic study of grey matter volume increase after early treatment in anti-psychotic naïve, newly diagnosed schizophrenia.

Psychopharmacology (Berl) 2009 Oct 30;206(3):437-46. Epub 2009 Jul 30.

Department of Psychiatry, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong.

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http://dx.doi.org/10.1007/s00213-009-1619-zDOI Listing
October 2009

Novel sib pair selection strategy increases power in quantitative association analysis.

Behav Genet 2009 Sep 1;39(5):571-9. Epub 2009 Jul 1.

Department of Psychiatry, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1007/s10519-009-9284-xDOI Listing
September 2009

IGG3: a tool to rapidly integrate large genotype datasets for whole-genome imputation and individual-level meta-analysis.

Bioinformatics 2009 Jun 3;25(11):1449-50. Epub 2009 Apr 3.

Department of Biochemistry, The University of Hong Kong, Pokfulam, Hong Kong.

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http://dx.doi.org/10.1093/bioinformatics/btp183DOI Listing
June 2009

Variance components linkage analysis with repeated measurements.

Hum Hered 2009 27;67(4):237-47. Epub 2008 Jan 27.

Department of Biostatistics, University of Michigan, Ann Arbor, Mich., USA.

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http://dx.doi.org/10.1159/000194977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2880721PMC
May 2009

Genetics of schizophrenia spectrum disorders: looking back and peering ahead.

Ann Acad Med Singapore 2009 May;38(5):436-4

Department of Psychiatry, the University of Hong Kong, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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May 2009

Unidimensional nonnegative scaling for genome-wide linkage disequilibrium maps.

Int J Bioinform Res Appl 2008 ;4(4):417-34

Centre for Mathematical Imaging and Vision, and Department of Mathematics, Hong Kong Baptist University, Kowloon Tong, Hong Kong.

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http://dx.doi.org/10.1504/IJBRA.2008.021177DOI Listing
February 2009

The heritability of attitude toward economic risk.

Twin Res Hum Genet 2009 Feb;12(1):103-7

Department of Economics, Hong Kong University of Science and Technology, Hong Kong, China.

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http://dx.doi.org/10.1375/twin.12.1.103DOI Listing
February 2009

Association analyses of the interaction between the ADSS and ATM genes with schizophrenia in a Chinese population.

BMC Med Genet 2008 Dec 30;9:119. Epub 2008 Dec 30.

Institute of Neurological disorders, Tsinghua University, Department of Psychiatry, Yuquan Hospital, Tsinghua University, Bejing, 100049, PR China.

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http://bmcmedgenet.biomedcentral.com/articles/10.1186/1471-2
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http://dx.doi.org/10.1186/1471-2350-9-119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654671PMC
December 2008