Padraic G Fallon

Padraic G Fallon

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Padraic G Fallon

Publications by authors named "Padraic G Fallon"

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Keratinocyte interleukin-36 receptor expression orchestrates psoriasiform inflammation in mice.

Life Sci Alliance 2020 Apr 21;3(4). Epub 2020 Feb 21.

Department of Clinical Medicine, Trinity Translational Medicine Institute, Trinity College Dublin, Dublin, Ireland

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http://dx.doi.org/10.26508/lsa.201900586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035875PMC
April 2020

Highly efficient CRISPR-targeting of the murine Hipp11 intergenic region supports inducible human transgene expression.

Mol Biol Rep 2020 Feb 6;47(2):1491-1498. Epub 2019 Dec 6.

School of Biochemistry& Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/s11033-019-05204-9DOI Listing
February 2020

The high and lows of type 2 asthma and mouse models.

J Allergy Clin Immunol 2020 Feb 5;145(2):496-498. Epub 2019 Dec 5.

Mikrobiologisches Institut - Klinische Mikrobiologie, Immunologie und Hygiene, Universitätsklinikum Erlangen and Friedrich-Alexander Universität (FAU) Erlangen-Nürnberg, Erlangen, Germany.

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http://dx.doi.org/10.1016/j.jaci.2019.11.031DOI Listing
February 2020

Correction to: Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer.

Mol Cancer 2020 Jan 27;19(1):16. Epub 2020 Jan 27.

Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital & Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1186/s12943-020-1142-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6983966PMC
January 2020

Determining Coreceptor Expression and Function in Murine ILC2 Through Flow Cytometry Characterization and Coculture Techniques.

Methods Mol Biol 2020 ;2121:71-82

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/978-1-0716-0338-3_7DOI Listing
January 2020

Addition of a Viral Immunomodulatory Domain to Etanercept Generates a Bifunctional Chemokine and TNF Inhibitor.

J Clin Med 2019 Dec 20;9(1). Epub 2019 Dec 20.

Centro de Biología Molecular Severo Ochoa (Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid), Cantoblanco, 28049 Madrid, Spain.

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http://dx.doi.org/10.3390/jcm9010025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7020083PMC
December 2019

Schistosoma "Eggs-Iting" the Host: Granuloma Formation and Egg Excretion.

Front Immunol 2018 29;9:2492. Epub 2018 Oct 29.

School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.3389/fimmu.2018.02492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232930PMC
September 2019

IL-17E (IL-25) Enhances Innate Immune Responses during Skin Inflammation.

J Invest Dermatol 2019 Aug 6;139(8):1732-1742.e17. Epub 2019 Feb 6.

Department of Pathology and Immunology, Faculty of Medicine, University of Geneva, Geneva, Switzerland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0022202X193010
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http://dx.doi.org/10.1016/j.jid.2019.01.021DOI Listing
August 2019

Schistosoma mansoni Worm Infection Regulates the Intestinal Microbiota and Susceptibility to Colitis.

Infect Immun 2019 08 23;87(8). Epub 2019 Jul 23.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland

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http://dx.doi.org/10.1128/IAI.00275-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6652750PMC
August 2019

Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.

Immunity 2019 06 7;50(6):1412-1424.e6. Epub 2019 May 7.

School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.04.005DOI Listing
June 2019

Helminth Modulation of Lung Inflammation.

Trends Parasitol 2018 05 12;34(5):388-403. Epub 2018 Jan 12.

School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.pt.2017.12.007DOI Listing
May 2018

The emergence of the IL-36 cytokine family as novel targets for inflammatory diseases.

Ann N Y Acad Sci 2018 04 26;1417(1):23-34. Epub 2016 Oct 26.

National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1111/nyas.13280DOI Listing
April 2018

The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses.

Eur J Immunol 2018 04 15;48(4):705-715. Epub 2018 Feb 15.

Adjuvant Research Group, School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1002/eji.201747150DOI Listing
April 2018

A novel role for the macrophage galactose-type lectin receptor in mediating von Willebrand factor clearance.

Blood 2018 02 27;131(8):911-916. Epub 2017 Dec 27.

Irish Centre for Vascular Biology, Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1182/blood-2017-06-787853DOI Listing
February 2018

Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.

Cell 2018 01 14;172(3):517-533.e20. Epub 2017 Dec 14.

Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA; The Francis Crick Institute, London NW1A 1AT, UK; Department of Microbiology and Immunobiology & HMS Center for Immune Imaging, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786505PMC
January 2018

Composition of the Schistosoma mansoni worm secretome: Identification of immune modulatory Cyclophilin A.

PLoS Negl Trop Dis 2017 Oct 26;11(10):e0006012. Epub 2017 Oct 26.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1371/journal.pntd.0006012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681295PMC
October 2017

ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control.

J Exp Med 2017 Sep 26;214(9):2507-2521. Epub 2017 Jul 26.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland

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http://dx.doi.org/10.1084/jem.20170051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5584124PMC
September 2017

Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year.

J Allergy Clin Immunol 2017 01 5;139(1):166-172. Epub 2016 Sep 5.

Clinical Medicine, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital Crumlin, Dublin, Ireland; Paediatric Dermatology, Our Lady's Children's Hospital Crumlin, Dublin, Ireland. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00916749163089
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http://dx.doi.org/10.1016/j.jaci.2016.07.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207796PMC
January 2017

Perinatal Activation of the Interleukin-33 Pathway Promotes Type 2 Immunity in the Developing Lung.

Immunity 2016 12 6;45(6):1285-1298. Epub 2016 Dec 6.

Department of Pulmonary Medicine, Erasmus University Medical Center Rotterdam, Rotterdam 3015 GJ, the Netherlands; Laboratory of Immunoregulation and Mucosal Immunology, VIB Inflammation Research Center, Ghent 9050, Belgium; Department of Pulmonary Medicine, Ghent University, Ghent 9000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2016.10.031DOI Listing
December 2016

N-linked glycans within the A2 domain of von Willebrand factor modulate macrophage-mediated clearance.

Blood 2016 10 23;128(15):1959-1968. Epub 2016 Aug 23.

Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital, National Centre for Hereditary Coagulation Disorders, St. James's Hospital, Dublin, Ireland; and Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1182/blood-2016-04-709436DOI Listing
October 2016

Treatment of ongoing autoimmune encephalomyelitis with activated B-cell progenitors maturing into regulatory B cells.

Nat Commun 2016 07 11;7:12134. Epub 2016 Jul 11.

Institut Necker Enfants Malades, Immunology, Infectiology and Haematology Department, Inserm U1151, CNRS UMR 8253, 14 rue Maria Helena Vieira da Silva, CS 61431, Paris 75014, France.

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http://dx.doi.org/10.1038/ncomms12134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4942579PMC
July 2016

Interleukin 33: an innate alarm for adaptive responses beyond Th2 immunity-emerging roles in obesity, intestinal inflammation, and cancer.

Eur J Immunol 2016 05 13;46(5):1091-100. Epub 2016 Apr 13.

School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1002/eji.201545780DOI Listing
May 2016

New Insights into IL-10 Dependent and IL-10 Independent Mechanisms of Regulatory B Cell Immune Suppression.

J Clin Immunol 2016 05 23;36 Suppl 1:25-33. Epub 2016 Mar 23.

School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1007/s10875-016-0263-8DOI Listing
May 2016

A novel role for von Willebrand factor in the pathogenesis of experimental cerebral malaria.

Blood 2016 Mar 28;127(9):1192-201. Epub 2015 Oct 28.

Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College, Dublin, Ireland; National Centre for Hereditary Coagulation Disorders, St James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1182/blood-2015-07-654921DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4815815PMC
March 2016

Spontaneous atopic dermatitis is mediated by innate immunity, with the secondary lung inflammation of the atopic march requiring adaptive immunity.

J Allergy Clin Immunol 2016 Feb 20;137(2):482-91. Epub 2015 Aug 20.

Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Institute of Molecular Medicine, St James's Hospital, Dublin, Ireland. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.06.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4735016PMC
February 2016

The helminth T2 RNase ω1 promotes metabolic homeostasis in an IL-33- and group 2 innate lymphoid cell-dependent mechanism.

FASEB J 2016 Feb 21;30(2):824-35. Epub 2015 Oct 21.

*Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland; National Children's Research Centre, Our Lady's Children's Hospital, Dublin, Ireland; Obesity Immunology, Education and Research Centre, St. Vincent's University Hospital, University College Dublin, Dublin, Ireland; Department of Endocrinology, St. Vincent's University Hospital, Elm Park, Dublin, Ireland; Division of Cellular Immunology, German Cancer Research Center, Heidelberg, Germany; and Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom

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http://dx.doi.org/10.1096/fj.15-277822DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4973506PMC
February 2016

Group 2 innate lymphoid cells license dendritic cells to potentiate memory TH2 cell responses.

Nat Immunol 2016 Jan 2;17(1):57-64. Epub 2015 Nov 2.

Medical Research Council, Laboratory of Molecular Biology, Cambridge, Cambridgeshire, UK.

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http://dx.doi.org/10.1038/ni.3294DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4685755PMC
January 2016

Macrophage and Innate Lymphoid Cell Interplay in the Genesis of Fibrosis.

Front Immunol 2015 23;6:597. Epub 2015 Nov 23.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin , Dublin , Ireland.

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http://dx.doi.org/10.3389/fimmu.2015.00597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655423PMC
December 2015

Ligation of TLR7 on CD19(+) CD1d(hi) B cells suppresses allergic lung inflammation via regulatory T cells.

Eur J Immunol 2015 Jun 14;45(6):1842-54. Epub 2015 Apr 14.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland.

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http://dx.doi.org/10.1002/eji.201445211DOI Listing
June 2015

Bcl11b is essential for group 2 innate lymphoid cell development.

J Exp Med 2015 Jun 11;212(6):875-82. Epub 2015 May 11.

Medical Research Council (MRC) Laboratory of Molecular Biology, Cambridge CB2 0QH, England, UK

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http://dx.doi.org/10.1084/jem.20142224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451131PMC
June 2015

Functional conservation of an ancestral Pellino protein in helminth species.

Sci Rep 2015 Jun 29;5:11687. Epub 2015 Jun 29.

1] School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland [2] National Children's Research Centre, Our Lady's Children's Hospital, Dublin 8, Ireland.

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http://dx.doi.org/10.1038/srep11687DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484250PMC
June 2015

An enhanced in vivo stable isotope labeling by amino acids in cell culture (SILAC) model for quantification of drug metabolism enzymes.

Mol Cell Proteomics 2015 Mar 5;14(3):750-60. Epub 2015 Jan 5.

From the ‡Jacqui Wood Cancer Centre, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY, Scotland;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.M114.043661
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http://dx.doi.org/10.1074/mcp.M114.043661DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349992PMC
March 2015

The generation of regulatory B cells by helminth parasites.

Methods Mol Biol 2014 ;1190:143-62

School of Medicine, Trinity Biomedical Sciences Institute, , Trinity College Dublin, College Green, Dublin 2, Ireland.

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http://dx.doi.org/10.1007/978-1-4939-1161-5_11DOI Listing
February 2015

Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer.

Mol Cancer 2015 Feb 20;14:45. Epub 2015 Feb 20.

Thoracic Oncology Research Group, School of Clinical Medicine, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St. James's Hospital & Trinity College Dublin, Dublin, Ireland.

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http://www.brimr.org/Reprints/135.pdf
Web Search
http://molecular-cancer.biomedcentral.com/articles/10.1186/s
Publisher Site
http://dx.doi.org/10.1186/s12943-015-0310-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392793PMC
February 2015

PD-L1hi B cells are critical regulators of humoral immunity.

Nat Commun 2015 Jan 22;6:5997. Epub 2015 Jan 22.

1] Translational Immunology Group, School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland [2] National Children's Research Centre, Our Lady's Children's Hospital, Dublin 12, Ireland [3] Institute of Molecular Medicine, School of Medicine St James's Hospital, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1038/ncomms6997DOI Listing
January 2015

The alarmin IL-33 promotes regulatory T-cell function in the intestine.

Nature 2014 Sep 16;513(7519):564-568. Epub 2014 Jul 16.

Translational Gastroenterology Unit, Nuffield Department of Clinical Medicine, Experimental Medicine Division, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK.

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http://dx.doi.org/10.1038/nature13577DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339042PMC
September 2014

Aging impairs peritoneal but not bone marrow-derived macrophage phagocytosis.

Aging Cell 2014 Aug 12;13(4):699-708. Epub 2014 May 12.

Centre for Infection and Immunity, Queen's University Belfast, 97 Lisburn Road, Belfast, BT9 7AE, Northern Ireland.

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http://dx.doi.org/10.1111/acel.12223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326936PMC
August 2014

Farnesoid X receptor agonists attenuate colonic epithelial secretory function and prevent experimental diarrhoea in vivo.

Gut 2014 May 5;63(5):808-17. Epub 2013 Aug 5.

Department of Molecular Medicine, RCSI Education and Research Centre, Beaumont Hospital, , Dublin, Ireland.

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http://dx.doi.org/10.1136/gutjnl-2013-305088DOI Listing
May 2014

MyD88 adaptor-like (Mal) regulates intestinal homeostasis and colitis-associated colorectal cancer in mice.

Am J Physiol Gastrointest Liver Physiol 2014 May 6;306(9):G769-78. Epub 2014 Mar 6.

Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland;

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http://dx.doi.org/10.1152/ajpgi.00399.2013DOI Listing
May 2014

A mineral extract from red algae ameliorates chronic spontaneous colitis in IL-10 deficient mice in a mouse strain dependent manner.

Phytother Res 2014 Feb 4;28(2):300-4. Epub 2013 Apr 4.

School of Medicine, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.

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http://dx.doi.org/10.1002/ptr.4989DOI Listing
February 2014

The Toll-like receptor 3 L412F polymorphism and disease progression in idiopathic pulmonary fibrosis.

Am J Respir Crit Care Med 2013 Dec;188(12):1442-50

1 School of Medicine and Medical Science, College of Life Sciences, UCD Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Dublin, Ireland.

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http://dx.doi.org/10.1164/rccm.201304-0760OCDOI Listing
December 2013

Cutting edge: IL-25 elicits innate lymphoid type 2 and type II NKT cells that regulate obesity in mice.

J Immunol 2013 Dec 28;191(11):5349-53. Epub 2013 Oct 28.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland;

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http://dx.doi.org/10.4049/jimmunol.1301176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3847854PMC
December 2013

A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis.

J Exp Med 2013 Dec 9;210(13):2939-50. Epub 2013 Dec 9.

Medical Research Council (MRC) Human Immunology Unit, National Institute for Health Research Biomedical Research Centre, Radcliffe Department of Medicine, University of Oxford, Oxford OX3 9DS, England, UK.

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http://dx.doi.org/10.1084/jem.20130351DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3865470PMC
December 2013

Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.

Proc Natl Acad Sci U S A 2013 Nov 21;110(46):18490-5. Epub 2013 Oct 21.

Systems Biology Ireland, School of Medicine and Medical Science, and Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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http://dx.doi.org/10.1073/pnas.1309718110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3832034PMC
November 2013

Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis.

Nat Immunol 2013 Sep 28;14(9):927-36. Epub 2013 Jul 28.

Institute of Immunology, Department of Biology, National University of Ireland Maynooth, Ireland.

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http://dx.doi.org/10.1038/ni.2669DOI Listing
September 2013

Toll IL-1R8/single Ig IL-1-related receptor regulates psoriasiform inflammation through direct inhibition of innate IL-17A expression by γδ T cells.

J Immunol 2013 Sep 14;191(6):3337-46. Epub 2013 Aug 14.

Department of Clinical Medicine, School of Medicine, Trinity College, Dublin 8, Ireland.

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http://dx.doi.org/10.4049/jimmunol.1300828DOI Listing
September 2013

Soluble IL-2Rα (sCD25) exacerbates autoimmunity and enhances the development of Th17 responses in mice.

PLoS One 2012 15;7(10):e47748. Epub 2012 Oct 15.

Department of Clinical Medicine, School of Medicine, Trinity College Dublin, Dublin, Ireland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0047748PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471880PMC
April 2013

Participation of MyD88 and interleukin-33 as innate drivers of Th2 immunity to Trichinella spiralis.

Infect Immun 2013 Apr 12;81(4):1354-63. Epub 2013 Feb 12.

Baker Institute for Animal Health, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.

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http://dx.doi.org/10.1128/IAI.01307-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639596PMC
April 2013

Regulation of Foxp3+ inducible regulatory T cell stability by SOCS2.

J Immunol 2013 Apr 1;190(7):3235-45. Epub 2013 Mar 1.

Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast BT9 7AE, Northern Ireland, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.1201396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3607399PMC
April 2013

The schistosoma granuloma: friend or foe?

Front Immunol 2013 15;4:89. Epub 2013 Apr 15.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin Dublin, Ireland ; National Children's Research Centre, Our Lady's Children's Hospital Dublin, Ireland.

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http://dx.doi.org/10.3389/fimmu.2013.00089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625856PMC
April 2013

Helminth therapies: translating the unknown unknowns to known knowns.

Int J Parasitol 2013 Mar 3;43(3-4):293-9. Epub 2013 Jan 3.

Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, and National Children's Research Centre, Our Lady's Children's Hospital, Ireland.

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http://dx.doi.org/10.1016/j.ijpara.2012.12.002DOI Listing
March 2013

Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia.

Nat Commun 2012 ;3:1119

Department of Biology, Institute of Immunology, National University of Ireland Maynooth, Maynooth, Ireland.

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http://dx.doi.org/10.1038/ncomms2127DOI Listing
February 2013

Suppressors of cytokine signaling 2 and 3 diametrically control macrophage polarization.

Immunity 2013 Jan 21;38(1):66-78. Epub 2012 Nov 21.

Centre for Infection and Immunity, School of Medicine Dentistry and Biomedical Sciences, Queen's University, 97 Lisburn Road, Belfast BT9 7BL, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S10747613120047
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http://dx.doi.org/10.1016/j.immuni.2012.09.013DOI Listing
January 2013

Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27.

J Immunol 2012 Sep 25;189(5):2079-83. Epub 2012 Jul 25.

Centre for Infection and Immunity, Queen's University Belfast, Belfast BT9 7AE, Northern Ireland.

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http://dx.doi.org/10.4049/jimmunol.1200131DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3424384PMC
September 2012

Innate type 2 cells and asthma.

Curr Opin Pharmacol 2012 Aug 29;12(4):503-9. Epub 2012 Jun 29.

Institute of Molecular Medicine, Trinity College Dublin, Ireland.

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http://dx.doi.org/10.1016/j.coph.2012.06.001DOI Listing
August 2012

The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α.

J Biol Chem 2012 Jul 31;287(30):25440-53. Epub 2012 May 31.

Institute of Immunology, National University of Ireland Maynooth, County Kildare, Ireland.

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http://dx.doi.org/10.1074/jbc.M112.371757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3408184PMC
July 2012

Lipid rafts are disrupted in mildly inflamed intestinal microenvironments without overt disruption of the epithelial barrier.

Am J Physiol Gastrointest Liver Physiol 2012 Apr 12;302(8):G781-93. Epub 2012 Jan 12.

Department of Surgery, Royal College of Surgeons in Ireland, Dublin, Ireland.

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http://dx.doi.org/10.1152/ajpgi.00002.2011DOI Listing
April 2012

Enhancement of chemokine function as an immunomodulatory strategy employed by human herpesviruses.

PLoS Pathog 2012 Feb 2;8(2):e1002497. Epub 2012 Feb 2.

Department of Virology and Microbiology, Centro de Biología Molecular Severo Ochoa, Consejo Superior de Investigaciones Científicas - Universidad Autónoma de Madrid, Madrid, Spain.

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http://dx.doi.org/10.1371/journal.ppat.1002497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271085PMC
February 2012

The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses.

Science 2012 Feb 9;335(6071):984-9. Epub 2012 Feb 9.

Department of Pathology and Immunology, University of Geneva, 1 rue Michel Servet, 1211 Geneva 4, Switzerland.

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http://dx.doi.org/10.1126/science.1215418DOI Listing
February 2012

Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide.

Clin Immunol 2011 Aug 13;140(2):196-207. Epub 2011 Apr 13.

Institute of Molecular Medicine, Trinity College Dublin, St James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.clim.2011.03.016DOI Listing
August 2011

Blockade of B7-H1 (programmed death ligand 1) enhances humoral immunity by positively regulating the generation of T follicular helper cells.

J Immunol 2011 May 13;186(10):5648-55. Epub 2011 Apr 13.

Institute of Molecular Medicine, St. James's Hospital, Trinity College Dublin, Dublin 8, Ireland.

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http://www.jimmunol.org/cgi/doi/10.4049/jimmunol.1003161
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http://dx.doi.org/10.4049/jimmunol.1003161DOI Listing
May 2011

Mast cells as sensors of cell injury through IL-33 recognition.

J Immunol 2011 Feb 14;186(4):2523-8. Epub 2011 Jan 14.

Clinical Immunology and Allergy Unit, Department of Medicine, Karolinska Institute, SE-171 76 Stockholm, Sweden.

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http://dx.doi.org/10.4049/jimmunol.1003383DOI Listing
February 2011

Effect of filaggrin breakdown products on growth of and protein expression by Staphylococcus aureus.

J Allergy Clin Immunol 2010 Dec 30;126(6):1184-90.e3. Epub 2010 Oct 30.

Moyne Institute of Preventive Medicine, Trinity College, Dublin, Ireland.

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http://dx.doi.org/10.1016/j.jaci.2010.09.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3627960PMC
December 2010