Pablo Villoslada

Pablo Villoslada

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Pablo Villoslada

Publications by authors named "Pablo Villoslada"

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Evaluation of the 3D fractal dimension as a marker of structural brain complexity in multiple-acquisition MRI.

Hum Brain Mapp 2019 08 15;40(11):3299-3320. Epub 2019 May 15.

Systems Biology Unit, Department of Experimental Biology, Universidad de Jaén, Jaén, Spain.

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http://dx.doi.org/10.1002/hbm.24599DOI Listing
August 2019

Antigen-specific tolerance to self-antigens in protein replacement therapy, gene therapy and autoimmunity.

Curr Opin Immunol 2019 Aug 30;61:46-53. Epub 2019 Aug 30.

Stanford University School of Medicine, Stanford, CA 94305, United States.

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http://dx.doi.org/10.1016/j.coi.2019.07.011DOI Listing
August 2019

Personalizing medical care for patients with MS: Monitoring brainstem damage by infrared oculography.

Neurology 2019 May 19;92(20):929-930. Epub 2019 Apr 19.

From Stanford University (P.V.), CA; Institut d'Investigacions Biomèdiques August Pi Sunyer (P.V.), Barcelona, Spain; Weill Institute for Neurosciences (A.J.G.), Division of Neuroimmunology and Glial Biology, Department of Neurology, University of California, San Francisco; Department of Ophthalmology (A.J.G.), UCSF; and New York University (S.G.), NY.

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http://dx.doi.org/10.1212/WNL.0000000000007493DOI Listing
May 2019

Harnessing electronic medical records to advance research on multiple sclerosis.

Mult Scler 2019 03 9;25(3):408-418. Epub 2018 Jan 9.

MS Genetics, Department of Neurology, School of Medicine, University of California San Francisco (UCSF), San Francisco, CA, USA/Université de Nantes, INSERM, UMR 1064, ATIP-Avenir, Equipe 5 Centre de Recherche en Transplantation et Immunologie, Nantes, France.

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http://dx.doi.org/10.1177/1352458517747407DOI Listing
March 2019

Remyelination: a good neuroprotective strategy for preventing axonal degeneration?

Brain 2019 02;142(2):233-236

Institut d'Investigacions Biomediques August Pi Sunyer and Hospital Clinic, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1093/brain/awy349DOI Listing
February 2019

Assessing Biological and Methodological Aspects of Brain Volume Loss in Multiple Sclerosis.

JAMA Neurol 2018 10;75(10):1246-1255

Center of Neuroimmunology Department of Neurology, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1001/jamaneurol.2018.1596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233851PMC
October 2018

Early retinal atrophy predicts long-term visual impairment after acute optic neuritis.

Mult Scler 2018 08 3;24(9):1196-1204. Epub 2017 Jul 3.

Center of Neuroimmunology, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain/University of California San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458517718628DOI Listing
August 2018

Anti-Basal Ganglia Antibodies and Streptococcal Infection in ADHD.

J Atten Disord 2018 07 16;22(9):864-871. Epub 2015 Apr 16.

2 Clínica Universidad de Navarra, Pamplona, Spain.

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http://journals.sagepub.com/doi/10.1177/1087054715580841
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http://dx.doi.org/10.1177/1087054715580841DOI Listing
July 2018

Subgenual anterior cingulate cortex controls sadness-induced modulations of cognitive and emotional network hubs.

Sci Rep 2018 06 4;8(1):8566. Epub 2018 Jun 4.

Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1038/s41598-018-26317-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986810PMC
June 2018

Combined walking outcome measures identify clinically meaningful response to prolonged-release fampridine.

Ther Adv Neurol Disord 2018 10;11:1756286418780007. Epub 2018 Jun 10.

Service of Neurology, Hospital Clinic, University of Barcelona, Spain Neuroimmunology Program, Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1177/1756286418780007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024337PMC
June 2018

Multicenter reliability of semiautomatic retinal layer segmentation using OCT.

Neurol Neuroimmunol Neuroinflamm 2018 May 13;5(3):e449. Epub 2018 Mar 13.

NeuroCure Clinical Research Center (T.O., F.P., A.U.B.), Charité-Universitätsmedizin Berlin, Germany; Department of Ophthalmology (G.L.T.), University Hospital Zurich, University of Zurich; Neuroimmunology and Multiple Sclerosis Research Section (S.L., S.S.), Department of Neurology, University Hospital Zurich, University of Zurich, Switzerland; Center of Neuroimmunology (I.G., P.V.), Institut d'Investigacions Biomediques August Pi Sunyer (IDIBAPS)-Hospital Clinic, Barcelona, Spain; Division of Neuroinflammation and Glial Biology (R.N., C.S., A.J.G.), Department of Neurology, University of California San Francisco; Neuro-ophthalmology Division (A.J.G.), Department of Ophthalmology, University of California, San Francisco; Multiple Sclerosis Center (L.B., A.P.), Departments of Neurology and Ophthalmology, Neuro-ophthalmology Expertise Centre, VUmc, Amsterdam and Moorfields Eye Hospital (A.P.), The National Hospital for Neurology and Neurosurgery and UCL, United Kingdom; Clinical and Experimental Multiple Sclerosis Research Center (F.P.), Department of Neurology, Charité-Universitätsmedizin Berlin; Experimental and Clinical Research Center (F.P., A.U.B.), Charité-Universitätsmedizin Berlin and Max-Delbrück Center for Molecular Medicine, Germany; Department of Methods and Experimental Psychology (I.G.), Faculty of Psychology and Education, Universidad de Deusto, Bilbao, Spain.

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http://dx.doi.org/10.1212/NXI.0000000000000449DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5852947PMC
May 2018

Identification and treatment of the visual processing asymmetry in MS patients with optic neuritis: The Pulfrich phenomenon.

J Neurol Sci 2018 04 3;387:60-69. Epub 2018 Feb 3.

Department of Neurology, Dell Medical School, University of Texas at Austin, TX, USA; School of Biomedical Engineering, University of Texas at Dallas, Richardson, TX, USA; Behavioral and Brain Sciences, University of Texas at Dallas, Richardson, TX, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2018.01.029DOI Listing
April 2018

OCT as a window to the MS brain: The view becomes slightly clearer.

Neurology 2017 12 15;89(24):2404-2405. Epub 2017 Nov 15.

From Queen Square MS Centre (A.T.T.), Department of Neuroinflammation, UCL Institute of Neurology, University College London, UK; John L. Trotter Multiple Sclerosis Center (R.T.N.), Department of Neurology, School of Medicine, Washington University in St. Louis, MO; and Center of Neuroimmunology (P.V.), Institut D'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1212/WNL.0000000000004755DOI Listing
December 2017

Time is vision: The importance of the early discovery and diagnosis of optic neuritis.

Mult Scler 2017 12;23(14):1806-1807

Center of Neuroimmunology, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS) and Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1177/1352458517739140DOI Listing
December 2017

Impairment of decision-making in multiple sclerosis: A neuroeconomic approach.

Mult Scler 2017 Nov 7;23(13):1762-1771. Epub 2016 Dec 7.

Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Neurology, Hospital Clinic of Barcelona, Barcelona, Spain/Department of Neurology, University of California-San Francisco (UCSF), San Francisco, CA, USA.

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http://dx.doi.org/10.1177/1352458516682103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047072PMC
November 2017

Structural networks involved in attention and executive functions in multiple sclerosis.

Neuroimage Clin 2017 5;13:288-296. Epub 2016 Dec 5.

Center of Neuroimmunology, Laboratory of Advanced Imaging in Neuroimmunological Diseases, Hospital Clinic Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS) and Universitat de Barcelona, Barcelona, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S22131582163023
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http://dx.doi.org/10.1016/j.nicl.2016.11.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192049PMC
November 2017

Retinal layer segmentation in multiple sclerosis: a systematic review and meta-analysis.

Lancet Neurol 2017 10 12;16(10):797-812. Epub 2017 Sep 12.

Department of Neurology, Amsterdam Neuroscience, VUmc MS Center Amsterdam and Dutch Expertise Centre for Neuro-ophthalmology, VU University Medical Center, Amsterdam, Netherlands.

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https://linkinghub.elsevier.com/retrieve/pii/S14744422173027
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http://dx.doi.org/10.1016/S1474-4422(17)30278-8DOI Listing
October 2017

Correction to: the disruption of mitochondrial axonal transport is an early event in neuroinflammation.

J Neuroinflammation 2017 10 23;14(1):206. Epub 2017 Oct 23.

Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Cellex Building, Laboratory 3A, Casanova 145, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12974-017-0979-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5654101PMC
October 2017

Dynamics and heterogeneity of brain damage in multiple sclerosis.

PLoS Comput Biol 2017 Oct 26;13(10):e1005757. Epub 2017 Oct 26.

Center for Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1371/journal.pcbi.1005757DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5657613PMC
October 2017

Burden of neurological diseases in the US revealed by web searches.

PLoS One 2017 22;12(5):e0178019. Epub 2017 May 22.

University of California of San Francisco, San Francisco, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178019PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5439713PMC
September 2017

Epicenters of dynamic connectivity in the adaptation of the ventral visual system.

Hum Brain Mapp 2017 04 28;38(4):1965-1976. Epub 2016 Dec 28.

Gordon Center For Medical Imaging, Department of Radiology, Division of Nuclear Medicine and Molecular Imaging, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/hbm.23497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342908PMC
April 2017

Metabolomic signatures associated with disease severity in multiple sclerosis.

Neurol Neuroimmunol Neuroinflamm 2017 Mar 27;4(2):e321. Epub 2017 Jan 27.

Center of Neuroimmunology (P.V., I.A., E.K., I.Z., I.P.-V., A.S.), Institute d'Investigaciones Biomediques August Pi Sunyer (IDIBAPS)-Hospital Clinic, Barcelona, Spain; University of California (P.V.), San Francisco; OWL (C.A., A.C.), Parque Tecnológico de Bizkaia, Derio; Cemcat (M.C., X.M.), Hospital Vall d'Hebron, Barcelona; Hospital Ramon y Cajal (L.V., J.C.A.-C.), Madrid; Hospital Universitario Regional (O.F.), Instituto de Investigación Biomédica (IBIMA), Malaga; and Hospital Clinico San Carlos (R.A.-L., R.A.), Madrid, Spain.

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http://dx.doi.org/10.1212/NXI.0000000000000321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278923PMC
March 2017

Reproducibility of the Structural Connectome Reconstruction across Diffusion Methods.

J Neuroimaging 2016 Jan-Feb;26(1):46-57. Epub 2015 Oct 14.

Center of Neuroimmunology, Institut d'Investigacions Biomedica August Pi Sunyer (IDIBAPS), Barcelona, Spain.

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http://dx.doi.org/10.1111/jon.12298DOI Listing
January 2017

Restoring immune tolerance in neuromyelitis optica: Part I.

Neurol Neuroimmunol Neuroinflamm 2016 Oct 7;3(5):e276. Epub 2016 Sep 7.

Department of Neurology (L.S.), Stanford University School of Medicine, Palo Alto, CA; Neuroimmunology Unit and Experimental Therapeutics Program (A.B.-O.), Montreal Neurological Institute and Hospital, McGill University, Montreal, Canada; The Guthy-Jackson Charitable Foundation (J.M.B.), San Diego, CA; Department of Gastroenterology (D.B.-R., P.V.), Hospital Clínic, CIBERehd and Center of Neuroimmunology & Inflammatory Bowel Disease, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Barcelona, Spain; Genentech, Inc. (P.S.C.), South San Francisco, CA; Department of Pathology (M.C.-S.), University of Florida School of Medicine, Gainesville; Opexa Therapeutics (D.H.), The Woodlands, TX; Department of Surgery (J.I.K.), Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Department of Biochemistry (D.M.K.), University of Illinois, Urbana; Neuroimmunology and MS Research (A.L., R.M., S.S.), Department of Neurology, University Hospital Zurich, University Zurich, Switzerland; Forest Landing Court (H.L.W.), Rockville, MD; Ann Romney Center for Neurologic Diseases (S.S.Z.), Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Neurology and Program in Immunology (H.L.W.), University of California, San Francisco School of Medicine; Department of Medicine (S.S.Z.), Divisions of Molecular Medicine & Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles; Harbor-UCLA Medical Center & LABioMed at Harbor-UCLA Medical Center (M.R.Y.), Torrance, CA; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, and Division of Metabolism and Endocrine Diseases, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor (T.J.S.).

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http://dx.doi.org/10.1212/NXI.0000000000000276DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015539PMC
October 2016

Restoring immune tolerance in neuromyelitis optica: Part II.

Neurol Neuroimmunol Neuroinflamm 2016 Oct 7;3(5):e277. Epub 2016 Sep 7.

Neuroimmunology Unit and Experimental Therapeutics Program (A.B.-O.), Montreal Neurological Institute and Hospital, McGill University, Montreal, Canada; Department of Neurology (L.S.), Stanford University School of Medicine, Palo Alto; The Guthy-Jackson Charitable Foundation (J.M.B.), San Diego, CA; Department of Gastroenterology (D.B.-R., P.V.), Hospital Clínic, CIBERehd and Center of Neuroimmunology & Inflammatory Bowel Disease, Institut d'Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain; Genentech, Inc. (P.S.C.), South San Francisco, CA; Department of Pathology (M.C.-S.), University of Florida School of Medicine, Gainesville; Opexa Therapeutics (D.H.), The Woodlands, TX; Department of Surgery (J.I.K.), Center for Transplantation Sciences, Massachusetts General Hospital, Harvard Medical School, Boston, MA; Department of Biochemistry (D.M.K.), University of Illinois, Urbana; Neuroimmunology and MS Research (A.L., R.M., S.S.), Department of Neurology, University Hospital Zurich, University Zurich, Switzerland; Ann Romney Center for Neurologic Diseases (H.L.W.), Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA; Department of Neurology and Program in Immunology (S.S.Z.), University of California, San Francisco School of Medicine; Department of Ophthalmology and Visual Sciences (T.J.S.), Kellogg Eye Center, and Division of Metabolism, Endocrine and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor; Department of Medicine (M.R.Y.), Divisions of Molecular Medicine & Infectious Diseases, David Geffen School of Medicine at UCLA, Los Angeles; and Harbor-UCLA Medical Center & LABioMed at Harbor-UCLA Medical Center (M.R.Y.), Torrance, CA.

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http://dx.doi.org/10.1212/NXI.0000000000000277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015540PMC
October 2016

Usefulness of optical coherence tomography to distinguish optic neuritis associated with AQP4 or MOG in neuromyelitis optica spectrum disorders.

Ther Adv Neurol Disord 2016 Sep 15;9(5):436-40. Epub 2016 Aug 15.

Center of Neuroimmunology and Service of Neurology, August Pi Sunyer Institute of Biomedical Research, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1177/1756285616655264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994783PMC
September 2016

Phenytoin for neuroprotection.

Lancet Neurol 2016 08;15(9):901-902

Institut d'Investigacions Biomèdiques August Pi Sunyer, Barcelona, Spain; University of California, San Francisco, San Francisco, CA, USA.

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http://dx.doi.org/10.1016/S1474-4422(16)30093-XDOI Listing
August 2016

The APOSTEL recommendations for reporting quantitative optical coherence tomography studies.

Neurology 2016 Jun 25;86(24):2303-9. Epub 2016 May 25.

From the Multiple Sclerosis Center (A.C.-H., P.V., A.J.G.), Department of Neurology, University of California San Francisco; Departments of Neurology and Ophthalmology (L.J.B., A.P.), VU University Medical Centre, Amsterdam, the Netherlands; Charité-Universitätsmedizin Berlin (T.O., F.P., A.U.B.), NeuroCure Clinical Research Center; Department of Neurology (T.O., F.P., A.U.B.), Experimental and Clinical Research Center, Max Delbrueck Center for Molecular Medicine, Berlin, Germany; Department of Neurology (S.S., P.C.), Johns Hopkins University, Baltimore, MD; Center of Neuroimmunology and Department of Neurology (E.H.M.-L., P.V.), Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Hospital Clinic of Barcelona, Spain; Eye Center (W.A.L.), University Medical Center, Freiburg, Germany; Departments of Ophthalmology (J.S.S.) and Neurology (L.B.), New York University School of Medicine, New York; Moorfields Eye Hospital and The National Hospital for Neurology and Neurosurgery (A.P.), London, UK; and Department of Neurology (P.A.), Medical Faculty, Heinrich-Heine University Düsseldorf, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000002774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4909557PMC
June 2016

Improved Framework for Tractography Reconstruction of the Optic Radiation.

PLoS One 2015 16;10(9):e0137064. Epub 2015 Sep 16.

Center of Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137064PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573981PMC
May 2016

Pituitary-ovary axis and ovarian reserve in fertile women with multiple sclerosis: A pilot study.

Mult Scler 2016 Apr 11;22(4):564-8. Epub 2015 Sep 11.

Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Spain

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http://dx.doi.org/10.1177/1352458515602339DOI Listing
April 2016

Visual field impairment captures disease burden in multiple sclerosis.

J Neurol 2016 Apr 9;263(4):695-702. Epub 2016 Feb 9.

Department of Neurology, Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clinic of Barcelona, University of Barcelona, Villarroel 170, Barcelona, ES, 08036, Spain.

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http://dx.doi.org/10.1007/s00415-016-8034-2DOI Listing
April 2016

Changes in macular layers in the early course of non-arteritic ischaemic optic neuropathy.

Graefes Arch Clin Exp Ophthalmol 2016 Mar 28;254(3):561-7. Epub 2015 May 28.

Department of Ophthalmology, Hospital Clínic de Barcelona, Barcelona, Spain.

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http://dx.doi.org/10.1007/s00417-015-3066-3DOI Listing
March 2016

Effects of diazoxide in multiple sclerosis: A randomized, double-blind phase 2 clinical trial.

Neurol Neuroimmunol Neuroinflamm 2015 Oct 10;2(5):e147. Epub 2015 Sep 10.

Institut d' Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)-Hospital Clinic (P.V., A.S.), Barcelona, Spain; Unitat de RM (Servei de Radiologia) (A.R., X.M.), Departamento de Neurología-Neuroinmunología, Centro de Esclerosis Múltiple de Cataluña (Cemcat), Hospital Vall d'Hebron, Barcelona, Spain; Hospital Clinico San Carlos (R.A., C.O.-G.), Madrid, Spain; NeuroCure Clinical Research Center and Department of Neurology (F.P.), Charité University Medicine Berlin, Berlin, Germany; Hospital de La Princesa (V.M.-L.), Madrid, Spain; Hospital Germans Trias i Pujol (C.R.), Badalona, Spain; Hospital Regional Universitario (IBIMA) (O.F.), Malaga, Spain; Hospital Puerta de Hierro (A.G.-M.), Madrid, Spain; Hospital Universitari Dr Josep Trueta (L.R.-T.), IDIBGI, Girona, Spain; Hospital La Fe (B.C.), Valencia, Spain; Hospital Xeral-Cies (D.M.), Vigo, Spain; Hospital del Mar (J.E.M.-R.), Barcelona, Spain; Deutsche Klinik für Diagnostik (E.L.), Wiesbaden, Germany; Hospital Universitario Santiago de Compostela (J.M.P.), Spain; Department of Neurology (S.G.M.), University of Munster, Germany; TrialFormSupport (X.N.), Barcelona, Spain; Advancell, Advanced In Vitro Cell Technologies, S.A (C.C.), Barcelona, Spain; and Neurotec Pharma S.L (M.P.), Barcelona, Spain.

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http://dx.doi.org/10.1212/NXI.0000000000000147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4567455PMC
October 2015

The analysis of semantic networks in multiple sclerosis identifies preferential damage of long-range connectivity.

Mult Scler Relat Disord 2015 Sep 8;4(5):387-394. Epub 2015 Jul 8.

Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic of Barcelona, Barcelona, Spain; Department of Neurology, University of California, San Francisco, USA. Electronic address:

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http://dx.doi.org/10.1016/j.msard.2015.07.002DOI Listing
September 2015

Update on biomarkers in neuromyelitis optica.

Neurol Neuroimmunol Neuroinflamm 2015 Aug 23;2(4):e134. Epub 2015 Jul 23.

Stanford University (E.M., M.H.H.), Stanford, CA; Johns Hopkins University (M.L.), Baltimore, MD; University of Oxford (P.J.W.), UK; Tohoku University (D.K.S.), Sendai, Japan; University of São Paulo (D.K.S.), Brazil; University of Colorado (J.L.B.), Denver; Mt. Sinai University (G.R.J.), New York, NY; Thomas Jefferson University (D.C.H.), Philadelphia, PA; IDIBAPS (A.S.), Barcelona, Spain; Montreal Neurological Institute and Hospital (A.B.-O.), McGill University, Montreal, Quebec, Canada; Research Institute and Hospital of National Cancer Center (H.J.K.), Goyang, Korea; KS Hegde Medical Academy (L.P.), Nitte University, Mangalore, India; Oxford University Hospital (M.I.L.), Oxford, UK; University of Southern Denmark (N.A.), Odense; Vejle Hospital (N.A.), Denmark; University Hospital (N.K.), Marrakech, Morocco; MS Center (R.H.), Erasmus MC University Medical Center, Rotterdam, the Netherlands; Service de Neurologie A (R.M.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Bron, France; Molecular Neuroimmunology (S.J.), Department of Neurology, University Hospital Heidelberg, Germany; Tandem Labs (J.M.), San Diego, CA; University of Michigan Medical School (T.J.S.), Ann Arbor, MI; and David Geffen School of Medicine (M.R.Y.), University of California, Los Angeles.

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http://dx.doi.org/10.1212/NXI.0000000000000134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516398PMC
August 2015

Acute optic neuritis: Unmet clinical needs and model for new therapies.

Neurol Neuroimmunol Neuroinflamm 2015 Aug 23;2(4):e135. Epub 2015 Jul 23.

Departments of Neurology (S.L.G., L.J.B.), Ophthalmology (S.L.G., L.J.B.), and Population Health (L.J.B.), New York University School of Medicine, New York, NY; Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) and Hospital Clinic of Barcelona (P.V.), Barcelona, Spain; Department of Neurology (P.V.), University of California, San Francisco; Department of Neurology (N.L.), The Agnes Ginges Center for Human Neurogenetics, Hadassah Hebrew-University Medical Center, Jerusalem, Israel; Scheie Eye Institute and FM Kirby Center for Molecular Ophthalmology (K.S.), University of Pennsylvania, Philadelphia; UPMC Eye Center (H.I.), Eye and Ear Institute, Ophthalmology and Visual Science Research Center, Department of Ophthalmology, University of Pittsburgh School of Medicine, PA; Department of Bioengineering (H.I.), Swanson School of Engineering, University of Pittsburgh, PA; Excel Scientific Solutions (E.P.), Southport, CT; and Biogen (D.C.), Cambridge, MA.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
Publisher Site
http://dx.doi.org/10.1212/NXI.0000000000000135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516397PMC
August 2015

The disruption of mitochondrial axonal transport is an early event in neuroinflammation.

J Neuroinflammation 2015 Aug 28;12:152. Epub 2015 Aug 28.

Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Cellex Building, Laboratory 3A, Casanova 145, 08036, Barcelona, Spain.

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http://dx.doi.org/10.1186/s12974-015-0375-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551771PMC
August 2015

Walking function in clinical monitoring of multiple sclerosis by telemedicine.

J Neurol 2015 Jul 10;262(7):1706-13. Epub 2015 May 10.

Service of Neurology, Hospital Clínic and Institut d´Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Center of Neuroimmunology, Universitat de Barcelona, Villarroel 170, 08036, Barcelona, Spain.

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July 2015

Challenges and opportunities in designing clinical trials for neuromyelitis optica.

Neurology 2015 Apr 3;84(17):1805-15. Epub 2015 Apr 3.

From the Department of Neurology (B.G.W.), Mayo Clinic, Rochester, MN; MedImmune Ltd. (G.B., A.F.), Riverside Building, Granta Park, Great Abington, Cambridge, UK; Guthy-Jackson Foundation (J.M.B., K.V.H.), San Diego, CA; Departments of Neurology and Ophthalmology (J.L.B.), University of Colorado Denver, Aurora; Novartis Pharmaceuticals Corporation (P.S.C.), East Hanover, NJ; Department of Neurology (B.A.C.C.), University of California San Francisco; CIC (Clinical Investigation Center) INSERM and UMR 1119 (J.d.S.), INSERM, Federation de Medecine Translationelle de Strasbourg, Université de Strasbourg; Department of Multiple Sclerosis Therapeutics (K.F.), Tohoku University, Sendai, Japan; Department of Neurology (B.G.), University of Texas Southwestern; Chugai Pharma USA (S.H., A.T.M.), Berkeley Heights, NJ; PPD Inc. (W.H.), Wilmington, NC; Department of Neurology (O.K.), Wayne State University, Detroit, MI; Teva Pharmaceuticals (V.K.), Frazer, PA; Department of Neurology (V.K.), Heinrich-Heine University, Dusseldorf, Germany; Department of Neurology (M.L.), Johns Hopkins University, Baltimore, MD; Department of Neurology (J.P.), Oxford University Hospital Trust, UK; Department of Ophthalmology and Visual Sciences (T.J.S.), Kellogg Eye Center, and Division of Metabolism, Endocrine, and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor; Department of Health Science (M.P.S.), University of Genoa, Italy; David Geffen School of Medicine at UCLA (K.V.H.), Los Angeles, CA; GlaxoSmithKline (S.V.), Research Triangle Park, NC; Center of Neuroimmunology (P.V.), Institute of Biomedical Research August Pi Sunyer (IDIBAPS)-Hospital Clinic Barcelona, Villarroel, Spain; United States Food and Drug Administration (M.K.W.), Center for Drug Evaluation and Research, Silver Spring, MD; Alexion Pharmaceuticals Inc. (W.W.), Cheshire, CT; Department of Neurology (D.M.W.), Mayo Clinic, Scottsdale, AZ; Department of Medicine (M.R.Y.), Divisions of M

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April 2015

A trifluoromethyl analogue of celecoxib exerts beneficial effects in neuroinflammation.

PLoS One 2013 11;8(12):e83119. Epub 2013 Dec 11.

Neurogenomiks Laboratory, University of Basque Country (UPV/ EHU), Zamudio, Spain ; Achucarro Basque Center for Neuroscience, Zamudio, Spain ; IKERBASQUE, Basque Foundation for Science, Bilbao, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859644PMC
March 2015

Dynamics of retinal injury after acute optic neuritis.

Ann Neurol 2015 Mar 14;77(3):517-28. Epub 2015 Feb 14.

Center of Neuroimmunology and Department of Neurology, August Pi Sunyer Institute of Biomedical Research, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.

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March 2015

MRI characteristics of neuromyelitis optica spectrum disorder: an international update.

Neurology 2015 Mar 18;84(11):1165-73. Epub 2015 Feb 18.

From the Department of Neurology (H.J.K., S.-H.K.), Research Institute and Hospital of National Cancer Center, Goyang, Korea; NeuroCure Clinical Research Center and Clinical and Experimental Multiple Sclerosis Research Center (F.P., J.W.), Department of Neurology, Charité University Medicine, Berlin, Germany; CIEM MS Research Center (M.A.L.-P.), Federal University of Minas Gerais Medical School, Belo Horizonte, Brazil; Department of Neurology (S.T.), National Paediatric Hospital Dr. Juan P. Garrahan, Buenos Aires, Argentina; Neurobiology (N.A.), Institute of Molecular Medicine, University of Southern Denmark; Department of Neurology (N.A.), Vejle Hospital, Denmark; Department of Clinical Neurology (J.P.), John Radcliffe Hospital, Oxford, UK; Department of Neurology, Massachusetts General Hospital (E.C.K.), Harvard Medical School, Boston, MA; Department of Neurology (D.K.S.), Tohoku University School of Medicine, Sendai, Japan; Neurology Department (J.d.S.), Hôpitaux Universitaires de Strasbourg, France; Institute of Neuroradiology (J.W.), University Medicine Goettingen, Germany; Department of Pediatrics (B.L.B.), Division of Neurology, The Children's Hospital of Philadelphia; Department of Neurology (B.L.B.), The University of Pennsylvania; Center of Neuroimmunology (P.V., A.S.), Service of Neurology, Hospital Clinic and Institute of Biomedical Research August Pi Sunyer, Barcelona, Spain; and Department of Multiple Sclerosis Therapeutics (K.F.), Tohoku University Graduate School of Medicine, Sendai, Japan.

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March 2015

Lesions in the posterior visual pathway promote trans-synaptic degeneration of retinal ganglion cells.

PLoS One 2014 23;9(5):e97444. Epub 2014 May 23.

The Institute of Ophthalmology and Center for Neuroimmunology, Institute of Biomedical Research August Pi Sunyer (IDIBAPS) - Hospital Clínic, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4032251PMC
February 2015

Signaling networks in MS: a systems-based approach to developing new pharmacological therapies.

Mult Scler 2015 Feb 11;21(2):138-46. Epub 2014 Aug 11.

Institute Biomedical Research August Pi Sunyer (IDIBAPS) - Hospital Clinic of Barcelona, Spain/Personal Biomedicine ZAO, and A. A. Kharkevich Institute for Information Transmission Problems, Russian Academy of Sciences, Russia

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February 2015

Intense immunosuppression for the treatment of an immune reconstitution inflammatory syndrome-like exacerbation after natalizumab withdrawal: a case report.

J Neurol 2015 Jan 20;262(1):219-21. Epub 2014 Nov 20.

Center for Neuroimmunology, Service of Neurology, Hospital Clínic and Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Universitat de Barcelona, Villarroel 170, 08036, Barcelona, Spain.

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January 2015

The multiple sclerosis visual pathway cohort: understanding neurodegeneration in MS.

BMC Res Notes 2014 Dec 15;7:910. Epub 2014 Dec 15.

Center of Neuroimmunology, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Hospital Clinic of Barcelona, Casanova 145, Planta 3A, 08036 Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4300678PMC
December 2014

Differential neuroprotective effects of 5'-deoxy-5'-methylthioadenosine.

PLoS One 2014 5;9(3):e90671. Epub 2014 Mar 5.

CIMA, Neurosciences Division, University of Navarra, Pamplona, Spain; Oncology Area, Lung Cancer Unit, Center for Biomedical Research of la Rioja (CIBIR), Logroño, Spain; Department of Neurosciences, University of Basque Country, Achucarro Basque Center for Neuroscience, Leioa, Spain; Institute of Neurobiology, Slovak Academy of Sciences, Kosice, Slovak Republic; Centro de Investigaciones Biomédicas en red en Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain; Department of Cellular Biology, Immunology and Neurosciences, Medicine School, University of Barcelona, Barcelona, Spain; Department of Neurology, University of Michigan Medical Center, Ann Arbor, Michigan, United States of America; Institute for Research in Biomedicine (IRB), Barcelona, Spain; Universidad de Castilla la Mancha, Albacete, Spain; Department of Biochemistry and Molecular Biology, School of Biology, University of Barcelona, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3944389PMC
November 2014

Autoimmunity and tumor immunology: two facets of a probabilistic immune system.

BMC Syst Biol 2014 Nov 11;8:120. Epub 2014 Nov 11.

Institute of Biomedical Research August Pi Sunyer (IDIBAPS), Hospital Clinic of Barcelona, Casanova 145, Cellex Center 3A, 08036, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4236429PMC
November 2014

Predicting relapsing-remitting dynamics in multiple sclerosis using discrete distribution models: a population approach.

PLoS One 2013 5;8(9):e73361. Epub 2013 Sep 5.

Indiana University School of Medicine; Indianapolis, Indiana, United States of America ; Indiana Clinical and Translational Sciences Institute (CTSI), Indianapolis, Indiana, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764125PMC
June 2014

Retrograde trans-synaptic degeneration in MS: a missing link?

Neurology 2014 Jun 16;82(24):2152-3. Epub 2014 May 16.

From the Mellen Center for Multiple Sclerosis Treatment and Research (R.A.B.), Cleveland Clinic, OH; and the Center of Neuroimmunology, Institute Biomedical Research August Pi Sunyer (IDIBAPS) (P.V.), Hospital Clinic of Barcelona, Spain.

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June 2014

Closing the clinical-radiological paradox using the visual pathway in multiple sclerosis.

Authors:
Pablo Villoslada

Invest Ophthalmol Vis Sci 2014 Jun 17;55(6):3765. Epub 2014 Jun 17.

Center of Neuroimmunology, Institute of Biomedical Research August Pi Sunyer (IDIBAPS) - Hospital Clinic Barcelona, Barcelona, Spain;

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June 2014

Cognitive functions in multiple sclerosis: impact of gray matter integrity.

Mult Scler 2014 Apr 4;20(4):424-32. Epub 2013 Sep 4.

Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Universitat de Barcelona, Barcelona, Spain.

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April 2014

Is the incidence of optic neuritis rising? Evidence from an epidemiological study in Barcelona (Spain), 2008-2012.

J Neurol 2014 Apr 16;261(4):759-67. Epub 2014 Feb 16.

Center of Neuroimmunology, Hospital Clinic of Barcelona, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Centre Cellex, Casanova 145, Planta 3A, 08036, Barcelona, Spain.

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April 2014

Evaluating structural connectomics in relation to different Q-space sampling techniques.

Med Image Comput Comput Assist Interv 2013 ;16(Pt 1):671-8

Center for Neuroimmunology, Department of Neurosciences, IDIBAPS, Hospital, Clinic, Barcelona, Spain.

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February 2014

Trans-synaptic axonal degeneration in the visual pathway in multiple sclerosis.

Ann Neurol 2014 Jan 2;75(1):98-107. Epub 2014 Jan 2.

Center of Neuroimmunology and Department of Neurology, August Pi i Sunyer Biomedical Research Institute, Hospital Clinic of Barcelona, Barcelona, Spain.

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January 2014

Retinal periphlebitis is associated with multiple sclerosis severity.

Neurology 2013 Sep 31;81(10):877-81. Epub 2013 Jul 31.

Center of Neuroimmunology, Department of Neurology, Institute of Biomedical Research August Pi Sunyer, Hospital Clinic of Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3885218PMC
September 2013

Analysis of prognostic factors associated with longitudinally extensive transverse myelitis.

Mult Scler 2013 May 4;19(6):742-8. Epub 2012 Oct 4.

Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d'Investigació Biomèdica August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.

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May 2013

Dynamic cross-regulation of antigen-specific effector and regulatory T cell subpopulations and microglia in brain autoimmunity.

BMC Syst Biol 2013 Apr 26;7:34. Epub 2013 Apr 26.

Center of Neuroimmunology, Institute of Biomedical Research August Pi Sunyer (IDIBAPS), Hospital Clinic of Barcelona, Barcelona, Spain.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3651362PMC
April 2013

Data integration and systems biology approaches for biomarker discovery: challenges and opportunities for multiple sclerosis.

J Neuroimmunol 2012 Jul 24;248(1-2):58-65. Epub 2012 Jan 24.

Center for Neuroimmunology, Institute of Biomedical Research August Pi Sunyer (IDIBAPS)-Hospital Clinic of Barcelona, Spain.

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July 2012

Color vision is strongly associated with retinal thinning in multiple sclerosis.

Mult Scler 2012 Jul 30;18(7):991-9. Epub 2012 Jan 30.

Center for Neuroimmunology, Institute of Biomedical Research August Pi Sunyer (IDIBAPS), Hospital Clinic of Barcelona, Spain.

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July 2012

Analysis of antibodies to surface epitopes of contactin-2 in multiple sclerosis.

J Neuroimmunol 2012 Mar 14;244(1-2):103-6. Epub 2012 Jan 14.

Center for Neuroimmunology, Service of Neurology, Hospital Clinic and Institut d' Investigació Biomèdica August Pi i Sunyer, Universitat de Barcelona, Barcelona, Spain.

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March 2012

[Guidelines on the appropriate use of animal models for developing therapies in multiple sclerosis].

Rev Neurol 2012 Jan;54(2):114-24

Institut d'Investigacions Biomèdiques August Pi i Sunyer, Hospital Clínic, Barcelona, España.

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January 2012

Systemic inflammation induces axon injury during brain inflammation.

Ann Neurol 2011 Dec;70(6):932-42

CNS Inflammation Group, School of Biological Sciences, University of Southampton, Southampton, UK.

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December 2011

Gain-of-function of P2X7 receptor gene variants in multiple sclerosis.

Cell Calcium 2011 Nov 8;50(5):468-72. Epub 2011 Sep 8.

Centro de Investigaciones Biomédicas en Red Enfermedades Neurodegenerativas (CIBERNED) and Departamento de Neurociencias, Universidad del País Vasco, Leioa, Spain.

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November 2011

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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August 2011