Pablo Hernaiz Driever

Pablo Hernaiz Driever

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Pablo Hernaiz Driever

Pablo Hernaiz Driever

Publications by authors named "Pablo Hernaiz Driever"

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62Publications

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Brainstem biopsy in pediatric diffuse intrinsic pontine glioma in the era of precision medicine: the INFORM study experience.

Eur J Cancer 2019 Jun 22;114:27-35. Epub 2019 Apr 22.

Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Heidelberg, Germany; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049193022
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http://dx.doi.org/10.1016/j.ejca.2019.03.019DOI Listing
June 2019

Motor function in survivors of pediatric acute lymphoblastic leukemia treated with chemotherapy-only.

Eur J Paediatr Neurol 2019 Mar 17;23(2):304-316. Epub 2018 Dec 17.

Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejpn.2018.12.005DOI Listing
March 2019

Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort.

Lancet Oncol 2018 06 9;19(6):785-798. Epub 2018 May 9.

Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany; Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany; Hopp Children's Cancer Center at the NCT Heidelberg, Heidelberg, Germany. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183024
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http://dx.doi.org/10.1016/S1470-2045(18)30242-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984248PMC
June 2018

DNA methylation-based classification of central nervous system tumours.

Authors:
David Capper David T W Jones Martin Sill Volker Hovestadt Daniel Schrimpf Dominik Sturm Christian Koelsche Felix Sahm Lukas Chavez David E Reuss Annekathrin Kratz Annika K Wefers Kristin Huang Kristian W Pajtler Leonille Schweizer Damian Stichel Adriana Olar Nils W Engel Kerstin Lindenberg Patrick N Harter Anne K Braczynski Karl H Plate Hildegard Dohmen Boyan K Garvalov Roland Coras Annett Hölsken Ekkehard Hewer Melanie Bewerunge-Hudler Matthias Schick Roger Fischer Rudi Beschorner Jens Schittenhelm Ori Staszewski Khalida Wani Pascale Varlet Melanie Pages Petra Temming Dietmar Lohmann Florian Selt Hendrik Witt Till Milde Olaf Witt Eleonora Aronica Felice Giangaspero Elisabeth Rushing Wolfram Scheurlen Christoph Geisenberger Fausto J Rodriguez Albert Becker Matthias Preusser Christine Haberler Rolf Bjerkvig Jane Cryan Michael Farrell Martina Deckert Jürgen Hench Stephan Frank Jonathan Serrano Kasthuri Kannan Aristotelis Tsirigos Wolfgang Brück Silvia Hofer Stefanie Brehmer Marcel Seiz-Rosenhagen Daniel Hänggi Volkmar Hans Stephanie Rozsnoki Jordan R Hansford Patricia Kohlhof Bjarne W Kristensen Matt Lechner Beatriz Lopes Christian Mawrin Ralf Ketter Andreas Kulozik Ziad Khatib Frank Heppner Arend Koch Anne Jouvet Catherine Keohane Helmut Mühleisen Wolf Mueller Ute Pohl Marco Prinz Axel Benner Marc Zapatka Nicholas G Gottardo Pablo Hernáiz Driever Christof M Kramm Hermann L Müller Stefan Rutkowski Katja von Hoff Michael C Frühwald Astrid Gnekow Gudrun Fleischhack Stephan Tippelt Gabriele Calaminus Camelia-Maria Monoranu Arie Perry Chris Jones Thomas S Jacques Bernhard Radlwimmer Marco Gessi Torsten Pietsch Johannes Schramm Gabriele Schackert Manfred Westphal Guido Reifenberger Pieter Wesseling Michael Weller Vincent Peter Collins Ingmar Blümcke Martin Bendszus Jürgen Debus Annie Huang Nada Jabado Paul A Northcott Werner Paulus Amar Gajjar Giles W Robinson Michael D Taylor Zane Jaunmuktane Marina Ryzhova Michael Platten Andreas Unterberg Wolfgang Wick Matthias A Karajannis Michel Mittelbronn Till Acker Christian Hartmann Kenneth Aldape Ulrich Schüller Rolf Buslei Peter Lichter Marcel Kool Christel Herold-Mende David W Ellison Martin Hasselblatt Matija Snuderl Sebastian Brandner Andrey Korshunov Andreas von Deimling Stefan M Pfister

Nature 2018 03 14;555(7697):469-474. Epub 2018 Mar 14.

Hopp Children's Cancer Center at the NCT Heidelberg (KiTZ), Heidelberg, Germany.

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http://dx.doi.org/10.1038/nature26000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6093218PMC
March 2018

Isolated optic nerve gliomas: a multicenter historical cohort study.

J Neurosurg Pediatr 2017 Dec 6;20(6):549-555. Epub 2017 Oct 6.

1The Gilbert Israeli Neurofibromatosis Center, Dana Children's Hospital.

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http://dx.doi.org/10.3171/2017.6.PEDS17107DOI Listing
December 2017

Haematological malignancies following temozolomide treatment for paediatric high-grade glioma.

Eur J Cancer 2017 08 3;81:1-8. Epub 2017 Jun 3.

Division of Pediatric Hematology and Oncology, Department of Child and Adolescent Health, University Medical Center Göttingen, Göttingen, Germany.

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http://dx.doi.org/10.1016/j.ejca.2017.04.023DOI Listing
August 2017

Cognitive and fine motor deficits in a pediatric sickle cell disease cohort of mixed ethnic origin.

Ann Hematol 2017 Feb 29;96(2):199-213. Epub 2016 Oct 29.

Klinik für Pädiatrie m.S. Onkologie/Hämatologie/KMT, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00277-016-2861-1DOI Listing
February 2017

DTI fiber tractography of cerebro-cerebellar pathways and clinical evaluation of ataxia in childhood posterior fossa tumor survivors.

J Neurooncol 2017 01 26;131(2):267-276. Epub 2016 Oct 26.

Pediatric Neurosurgery, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s11060-016-2290-yDOI Listing
January 2017

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.

Eur J Cancer 2016 09 29;65:91-101. Epub 2016 Jul 29.

Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 430, Heidelberg, 69120, Germany; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.06.009DOI Listing
September 2016

Long-term survival of an infant with an atypical teratoid/rhabdoid tumor following subtotal resection and low-cumulative dose chemotherapy: a case report.

Childs Nerv Syst 2016 Jun 8;32(6):1157-61. Epub 2016 Jan 8.

Department of Pediatric Oncology/Hematology/BMT, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00381-015-2999-5DOI Listing
June 2016

Executive function deficits in pediatric cerebellar tumor survivors.

Eur J Paediatr Neurol 2016 Jan 12;20(1):25-37. Epub 2015 Nov 12.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Germany; Department of Neurosurgery, University Hospital Würzburg, Germany.

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http://dx.doi.org/10.1016/j.ejpn.2015.11.001DOI Listing
January 2016

Cerebral white matter fractional anisotropy and tract volume as measured by MR imaging are associated with impaired cognitive and motor function in pediatric posterior fossa tumor survivors.

Pediatr Blood Cancer 2015 Jul 7;62(7):1252-8. Epub 2015 Apr 7.

Pediatric Neurooncology Program, Department of Pediatric Oncology and Hematology, Charité-CVK, Berlin, Germany.

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http://dx.doi.org/10.1002/pbc.25485DOI Listing
July 2015

Morphological brain lesions of pediatric cerebellar tumor survivors correlate with inferior neurocognitive function but do not affect health-related quality of life.

Childs Nerv Syst 2015 Apr 17;31(4):569-80. Epub 2015 Feb 17.

Pediatric Neurooncology Program, Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, D-13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00381-015-2635-4DOI Listing
April 2015

(18)F-FET-PET guided surgical biopsy and resection in children and adolescence with brain tumors.

Childs Nerv Syst 2015 Feb 18;31(2):261-7. Epub 2014 Sep 18.

Department of Neurosurgery, Charité Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00381-014-2552-yDOI Listing
February 2015

Levetiracetam as a possible cause of secondary graft failure after allogenic hematopoietic stem cell transplantation.

Eur J Paediatr Neurol 2015 Jan 5;19(1):75-7. Epub 2014 Nov 5.

Department of Pediatric Oncology/Hematology, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.ejpn.2014.10.004DOI Listing
January 2015

Inconsistent terminology for cerebellar mutism.

Childs Nerv Syst 2013 May 16;29(5):717-8. Epub 2013 Mar 16.

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http://dx.doi.org/10.1007/s00381-013-2074-zDOI Listing
May 2013

Fronto-cerebellar fiber tractography in pediatric patients following posterior fossa tumor surgery.

Childs Nerv Syst 2013 Apr 27;29(4):597-607. Epub 2012 Nov 27.

Arbeitsbereich Pädiatrische Neurochirurgie, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1007/s00381-012-1973-8DOI Listing
April 2013

Eurythmy therapy in the aftercare of pediatric posterior fossa tumour survivors--a pilot study.

Complement Ther Med 2013 Apr 23;21 Suppl 1:S3-9. Epub 2012 Mar 23.

Department of Pediatric Oncology and Hematology, Task Force Integrative Medicine in Pediatric Oncology, Charité - Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1016/j.ctim.2012.02.007DOI Listing
April 2013

Supratentorial neurometabolic alterations in pediatric survivors of posterior fossa tumors.

Int J Radiat Oncol Biol Phys 2012 Mar 12;82(3):1135-41. Epub 2011 Jun 12.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2011.04.017DOI Listing
March 2012

First case report of a peripheral T-cell lymphoma, not otherwise specified, of the central nervous system in a child.

J Pediatr Hematol Oncol 2012 Mar;34(2):e66-8

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1097/MPH.0b013e318219f95eDOI Listing
March 2012

Pediatric low-grade glioma survivors experience high quality of life.

Childs Nerv Syst 2011 Nov 3;27(11):1895-902. Epub 2011 May 3.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1007/s00381-011-1467-0DOI Listing
November 2011

Carboplatin and ototoxicity: hearing loss rates among survivors of childhood medulloblastoma.

Childs Nerv Syst 2011 Mar 8;27(3):407-13. Epub 2010 Oct 8.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1007/s00381-010-1300-1DOI Listing
March 2011

Oncomodulation by human cytomegalovirus: novel clinical findings open new roads.

Med Microbiol Immunol 2011 Feb 22;200(1):1-5. Epub 2010 Oct 22.

Institut für Medizinische Virologie, Klinikum der Goethe-Universität, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1007/s00430-010-0177-7DOI Listing
February 2011

Pediatric neuro-oncology in small centers--quality control of network support: the HIT-GBM experience.

Anticancer Res 2011 Feb;31(2):661-4

Division of Pediatrics, MD Anderson Cancer Center, Houston, TX, USA.

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February 2011

Natural history and management of low-grade glioma in NF-1 children.

J Neurooncol 2010 Nov 30;100(2):199-207. Epub 2010 Mar 30.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, Germany.

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http://dx.doi.org/10.1007/s11060-010-0159-zDOI Listing
November 2010

Ependymoma of the spinal cord in children and adolescents: a retrospective series from the HIT database.

J Neurosurg Pediatr 2010 Aug;6(2):137-44

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria.

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http://dx.doi.org/10.3171/2010.5.PEDS09553DOI Listing
August 2010

Differences in supratentorial damage of white matter in pediatric survivors of posterior fossa tumors with and without adjuvant treatment as detected by magnetic resonance diffusion tensor imaging.

Int J Radiat Oncol Biol Phys 2010 Mar 18;76(3):859-66. Epub 2009 Jun 18.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.ijrobp.2009.02.054DOI Listing
March 2010

Serum levels of Midkine in children and adolescents without malignant disease.

Pediatr Int 2010 Feb 18;52(1):75-9. Epub 2009 May 18.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1111/j.1442-200X.2009.02885.xDOI Listing
February 2010

Increased midkine serum levels in pediatric embryonal tumor patients.

J Pediatr Hematol Oncol 2009 Oct;31(10):713-7

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1097/MPH.0b013e3181b6db9fDOI Listing
October 2009

Loss of fine motor function correlates with ataxia and decline of cognition in cerebellar tumor survivors.

Pediatr Blood Cancer 2009 Sep;53(3):424-31

Pediatric Neurooncology Program, Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/pbc.22104DOI Listing
September 2009

Somatic mitochondrial mutations in pilocytic astrocytoma.

Cancer Genet Cytogenet 2009 Jul;192(1):30-5

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.03.002DOI Listing
July 2009

Effects of complementary eurythmy therapy on heart rate variability.

Complement Ther Med 2009 Jun 20;17(3):161-7. Epub 2008 Nov 20.

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Germany.

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http://dx.doi.org/10.1016/j.ctim.2008.09.005DOI Listing
June 2009

Valproic acid was well tolerated in heavily pretreated pediatric patients with high-grade glioma.

J Neurooncol 2008 Dec 5;90(3):309-14. Epub 2008 Aug 5.

Children's Cancer Hospital, Department of Pediatrics, Unit 87, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, USA.

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http://dx.doi.org/10.1007/s11060-008-9662-xDOI Listing
December 2008

Influence of age and movement complexity on kinematic hand movement parameters in childhood and adolescence.

Int J Dev Neurosci 2008 Nov 5;26(7):655-63. Epub 2008 Aug 5.

Pediatric Neurooncology Program, Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1016/j.ijdevneu.2008.07.015DOI Listing
November 2008

Spontaneous regression of a vascular tumor of the skull base--infantile hemangioendothelioma?

J Pediatr Hematol Oncol 2008 Sep;30(9):712-5

Departments of Pediatric Oncology and Hematology, Charité-Universitaetsmedizin Berlin, Campus Virchow-Klinikum, Augustenburger Platz 1, Berlin, Germany.

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http://dx.doi.org/10.1097/MPH.0b013e31817e4a06DOI Listing
September 2008

Occurrence of a spinal anaplastic pilocytic astrocytoma and a supratentorial PNET in an adolescent.

J Pediatr Hematol Oncol 2007 Dec;29(12):832-5

Department of Pediatric Oncology and Hematology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1097/MPH.0b013e3181580eb3DOI Listing
December 2007

Prenatal manifestation of pancytopenia in Pearson marrow-pancreas syndrome caused by a mitochondrial DNA deletion.

Am J Med Genet A 2007 Feb;143A(3):285-8

Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1002/ajmg.a.31493DOI Listing
February 2007

Acupuncture against chemotherapy-induced nausea and vomiting in pediatric oncology. Interim results of a multicenter crossover study.

Support Care Cancer 2006 Feb 14;14(2):172-6. Epub 2005 Jul 14.

Department of Pediatric Oncology/Hematology, Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00520-005-0846-zDOI Listing
February 2006

Overexpression of Midkine in malignant peripheral nerve sheath tumor cells inhibits apoptosis and increases angiogenic potency.

Int J Oncol 2005 Nov;27(5):1433-40

Department of Pediatric Oncology and Hematology, Campus Virchow Hospital, Charité-Universitätsmedizin Berlin, D-13353 Berlin, Germany.

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November 2005

Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression.

Int J Oncol 2005 Oct;27(4):1029-37

Interdisziplinäres Laboratorium für Tumor und Virus Forschung, Institut für Medizinische Virologie, Clinics of J-W. Goethe University, Frankfurt am Main, Germany.

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October 2005

Evolving anticancer drug valproic acid: insights into the mechanism and clinical studies.

Med Res Rev 2005 Jul;25(4):383-97

Zentrum der Chirurgie, Klinik für Urologie und Kinderurologie, Johann Wolfgang Goethe-Universität, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1002/med.20027DOI Listing
July 2005

Multimutated herpes simplex virus g207 is a potent inhibitor of angiogenesis.

Neoplasia 2004 Nov-Dec;6(6):725-35

Institute of Medical Virology, Center of Hygiene, Paul-Ehrlich Str. 40, Frankfurt am Main D-60596, Germany.

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http://dx.doi.org/10.1593/neo.04265DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1531676PMC
April 2005

Cancer risk in people with epilepsy: the role of antiepileptic drugs.

Brain 2005 Jan 1;128(Pt 1):7-17. Epub 2004 Dec 1.

Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, London, UK.

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http://dx.doi.org/10.1093/brain/awh363DOI Listing
January 2005

Valproic acid and interferon-alpha synergistically inhibit neuroblastoma cell growth in vitro and in vivo.

Int J Oncol 2004 Dec;25(6):1795-9

Institut für Medizinische Virologie, Klinikum der J.W. Goethe Universität, Paul Ehrlich-Str. 40, 60596 Frankfurt am Main, Germany.

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December 2004

Expression level of neural cell adhesion molecule (NCAM) inversely correlates with the ability of neuroblastoma cells to adhere to endothelium in vitro.

Cell Commun Adhes 2002 May-Jun;9(3):131-47

Zentrum der Hygiene, Institut für Medizinische Virologie, Klinikum der J. W Goethe-Universität, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1080/15419060214520DOI Listing
June 2003

Induction of differentiation and suppression of malignant phenotype of human neuroblastoma BE(2)-C cells by valproic acid: enhancement by combination with interferon-alpha.

Int J Oncol 2002 Jan;20(1):97-106

Institute for Medical Virology, Johann Wolfgang Goethe-University Medical Center, D-60596 Frankfurt am Main, Germany.

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January 2002