Peter Schraml

Peter Schraml

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Peter Schraml

Peter Schraml

Publications by authors named "Peter Schraml"

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Quantitative microimmunohistochemistry for the grading of immunostains on tumour tissues.

Nat Biomed Eng 2019 Apr 8. Epub 2019 Apr 8.

IBM Research-Zurich, Rüschlikon, Switzerland.

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http://dx.doi.org/10.1038/s41551-019-0386-3DOI Listing
April 2019

IL-8 and CXCR1 expression is associated with cancer stem cell-like properties of clear cell renal cancer.

J Pathol 2019 Mar 18. Epub 2019 Mar 18.

Department of Pathology and Molecular Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/path.5267DOI Listing
March 2019

Expression and Mutation Patterns of PBRM1, BAP1 and SETD2 Mirror Specific Evolutionary Subtypes in Clear Cell Renal Cell Carcinoma.

Neoplasia 2019 02 16;21(2):247-256. Epub 2019 Jan 16.

Department of Pathology and Molecular Pathology, University Hospital Zurich and University Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2018.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355619PMC
February 2019

Specific immune cell and lymphatic vessel signatures identified by image analysis in renal cancer.

Mod Pathol 2019 Feb 8. Epub 2019 Feb 8.

Department of Pathology and Molecular Pathology, University Hospital Zurich and University Zurich, Schmelzbergstrasse 12, CH-8091, Zurich, Switzerland.

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http://dx.doi.org/10.1038/s41379-019-0214-zDOI Listing
February 2019

Clear cell renal cell carcinoma with wild-type von Hippel-Lindau gene: a non-existent or new tumour entity?

Histopathology 2019 Jan;74(1):60-67

Department of Pathology and Molecular Pathology, University and University Hospital Zurich, Zurich, Switzerland.

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http://doi.wiley.com/10.1111/his.13749
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http://dx.doi.org/10.1111/his.13749DOI Listing
January 2019

Scavenger receptor BI promotes cytoplasmic accumulation of lipoproteins in clear-cell renal cell carcinoma.

J Lipid Res 2018 11 1;59(11):2188-2201. Epub 2018 Sep 1.

Institute of Clinical Chemistry University of Zurich and University Hospital of Zurich, Zurich, Switzerland

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http://dx.doi.org/10.1194/jlr.M083311DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6210910PMC
November 2018

Fluorocholine Transport Mediated by the Organic Cation Transporter 2 (OCT2, SLC22A2): Implication for Imaging of Kidney Tumors.

Drug Metab Dispos 2018 08 24;46(8):1129-1136. Epub 2018 May 24.

Departments of Clinical Pharmacology and Toxicology (M.V., A.T., Z.G., S.H., C.L., C.H., G.A.K.-U.) and Pathology and Molecular Pathology (P.H.S., H.M.), University Hospital Zurich, University of Zurich, Zurich, Switzerland; and Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China (C.L.).

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http://dx.doi.org/10.1124/dmd.118.081091DOI Listing
August 2018

Detailed simulation of cancer exome sequencing data reveals differences and common limitations of variant callers.

BMC Bioinformatics 2017 Jan 3;18(1). Epub 2017 Jan 3.

Department of Biosystems Science and Engineering, ETH Zurich, Mattenstr, Basel, 26, 4058, Switzerland.

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http://dx.doi.org/10.1186/s12859-016-1417-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5209852PMC
January 2017

PD-L1 expression is regulated by hypoxia inducible factor in clear cell renal cell carcinoma.

Int J Cancer 2016 07 25;139(2):396-403. Epub 2016 Mar 25.

Institute of Surgical Pathology, University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.1002/ijc.30077DOI Listing
July 2016

Interaction of tumor cells with infiltrating lymphocytes via CD70 and CD27 in clear cell renal cell carcinoma.

Oncoimmunology 2015 Dec 29;4(12):e1049805. Epub 2015 May 29.

Institute of Surgical Pathology; University Hospital Zürich ; Zürich, Switzerland.

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http://dx.doi.org/10.1080/2162402X.2015.1049805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635726PMC
December 2015

Clear cell papillary renal cell carcinoma and renal angiomyoadenomatous tumor: two variants of a morphologic, immunohistochemical, and genetic distinct entity of renal cell carcinoma.

Am J Surg Pathol 2015 Jul;39(7):889-901

*Institute of Surgical Pathology, University Hospital Zurich, Zurich ‡‡Cantonal Hospital Aarau §§Institute of Histological and Cytological Diagnostics, Aarau ¶¶University Institute of Pathology, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland †Institute of Pathology, University Medicine Göttingen (UMG), Göttingen ∥Institute of Pathology, University Hospital Tübingen, Tübingen ¶Institute of Pathology, HELIOS Hospital Berlin-Buch, Berlin #Institute of Pathology Bogenhausen, Städtisches Klinikum München GmbH, Munich **Institute of Pathology, Heinrich Heine University Hospital, Dusseldorf ††Institute of Pathology, RWTH University, Aachen ∥∥Institute of Pathology, HELIOS Hospital Schwerin, Schwerin ***Institute of Pathology, Städtisches Klinikum Karlsruhe gGmbH, Karlsruhe †††Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany ‡Service d'Anatomie et Cytologie Pathologiques 1, Groupe Hospitalier Pitié-Salpêtrière, Paris, France §Department of Medicine, Renal Division, Brigham and Women's Hospital, Boston, MA ##Institute of Pathology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.1097/PAS.0000000000000456DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4465996PMC
July 2015

Insulin-like growth factor I is expressed in classical and nodular lymphocyte-predominant Hodgkin's lymphoma tumour and microenvironmental cells.

Cell Tissue Res 2015 Mar 9;359(3):841-51. Epub 2014 Dec 9.

Research Group Neuro-endocrine-immune Interactions, Institute of Anatomy, University of Zurich, Zurich, Switzerland,

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http://dx.doi.org/10.1007/s00441-014-2052-0DOI Listing
March 2015

αv-Integrin isoform expression in primary human tumors and brain metastases.

Int J Cancer 2013 Nov 10;133(10):2362-71. Epub 2013 Jun 10.

Department of Pathology, Institute for Surgical Pathology, University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.1002/ijc.28267DOI Listing
November 2013

Identification of molecular tumor markers in renal cell carcinomas with TFE3 protein expression by RNA sequencing.

Neoplasia 2013 Nov;15(11):1231-40

Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland ; Life Science Zurich PhD Program on Molecular and Translational Biomedicine, Zurich, Switzerland ; Competence Center for Systems Physiology and Metabolic Diseases, Zurich, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3859447PMC
November 2013

Spontaneous peripheral T-cell responses toward the tumor-associated antigen cyclin D1 in patients with clear cell renal cell carcinoma.

Cancer Immunol Res 2013 Nov 25;1(5):288-95. Epub 2013 Sep 25.

Authors' Affiliations: Departments of Department of Immunology, Interfaculty Institute for Cell Biology, University of Tubingen, Tubingen, Germany.

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http://cancerimmunolres.aacrjournals.org/cgi/doi/10.1158/232
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http://dx.doi.org/10.1158/2326-6066.CIR-13-0113DOI Listing
November 2013

Onconeuronal antigen Cdr2 correlates with HIF prolyl-4-hydroxylase PHD1 and worse prognosis in renal cell carcinoma.

Exp Mol Pathol 2013 Jun 24;94(3):453-7. Epub 2013 Mar 24.

Institute of Physiology, University of Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.yexmp.2013.03.005DOI Listing
June 2013

KRAS, BRAF, and TP53 deep sequencing for colorectal carcinoma patient diagnostics.

J Mol Diagn 2013 May 24;15(3):299-311. Epub 2013 Mar 24.

Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1016/j.jmoldx.2013.02.001DOI Listing
May 2013

The protein tyrosine phosphatase receptor type J is regulated by the pVHL-HIF axis in clear cell renal cell carcinoma.

J Pathol 2013 Mar 21;229(4):525-34. Epub 2013 Jan 21.

Institute of Surgical Pathology, University Hospital Zurich, Schmelzbergstrasse 12, 8091, Zurich, Switzerland.

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http://doi.wiley.com/10.1002/path.4107
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http://dx.doi.org/10.1002/path.4107DOI Listing
March 2013

Integrin control of the transforming growth factor-β pathway in glioblastoma.

Brain 2013 Feb 31;136(Pt 2):564-76. Epub 2013 Jan 31.

Department of Neurology, University Hospital Zurich, Frauenklinikstrasse 26, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1093/brain/aws351DOI Listing
February 2013

Loss of PBRM1 expression is associated with renal cell carcinoma progression.

Int J Cancer 2013 Jan 3;132(2):E11-7. Epub 2012 Oct 3.

Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/ijc.27822DOI Listing
January 2013

Whole genome and transcriptome amplification: practicable tools for sustainable tissue biobanking?

Virchows Arch 2012 Nov 25;461(5):571-80. Epub 2012 Sep 25.

Institute of Surgical Pathology, University Hospital Zurich, Schmelzbergstrasse 12, 8091 Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00428-012-1315-yDOI Listing
November 2012

Characterization of periostin isoform pattern in non-small cell lung cancer.

Lung Cancer 2012 May 12;76(2):183-90. Epub 2011 Nov 12.

Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://linkinghub.elsevier.com/retrieve/pii/S016950021100528
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http://dx.doi.org/10.1016/j.lungcan.2011.10.013DOI Listing
May 2012

Reliable detection of subclonal single-nucleotide variants in tumour cell populations.

Nat Commun 2012 May 1;3:811. Epub 2012 May 1.

Department of Biosystems Science and Engineering, ETH Zurich, Mattenstrasse 26, 4058 Basel, Switzerland.

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http://dx.doi.org/10.1038/ncomms1814DOI Listing
May 2012

Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.

Nucleic Acids Res 2012 Mar 10;40(5):1928-43. Epub 2011 Nov 10.

Institute of Physiology and Zürich Center for Integrative Human Physiology (ZIHP), University of Zürich, 8057 Zürich, Switzerland.

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http://dx.doi.org/10.1093/nar/gkr978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3300025PMC
March 2012

KRAS mutation is associated with elevated myeloblastin activity in human lung adenocarcinoma.

Cancer Genomics Proteomics 2012 Jan;9(1):51-4

Division of Thoracic Surgery, Institute of Surgical Pathology, University Hospital Zurich, Raemistrasse 100, CH-8091 Zurich, Switzerland.

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January 2012

VHL gene mutations and their effects on hypoxia inducible factor HIFα: identification of potential driver and passenger mutations.

Cancer Res 2011 Aug 29;71(16):5500-11. Epub 2011 Jun 29.

Institute of Surgical Pathology, University Hospital Zurich, Switzerland.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-0757DOI Listing
August 2011

VHL mutations and dysregulation of pVHL- and PTEN-controlled pathways in multilocular cystic renal cell carcinoma.

Mod Pathol 2011 Apr 10;24(4):571-8. Epub 2010 Dec 10.

University Hospital Zurich, Institute of Surgical Pathology, Zurich, Switzerland.

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http://dx.doi.org/10.1038/modpathol.2010.222DOI Listing
April 2011

L1-CAM expression in ccRCC correlates with shorter patients survival times and confers chemoresistance in renal cell carcinoma cells.

Carcinogenesis 2011 Mar 19;32(3):262-70. Epub 2010 Nov 19.

Pharmacology, pharmazentrum frankfurt/ZAFES, University Hospital Goethe University Frankfurt, D 60590 Frankfurt am Main, Germany.

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http://dx.doi.org/10.1093/carcin/bgq249DOI Listing
March 2011

Mining tissue microarray data to uncover combinations of biomarker expression patterns that improve intermediate staging and grading of clear cell renal cell cancer.

Clin Cancer Res 2010 Jan 22;16(1):88-98. Epub 2009 Dec 22.

Department of Urology, University Hospital Zurich, Center for Systems Physiology and Metabolic Diseases, ETH Zurich, and Institute of Surgical Pathology, Zurich, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-09-0260DOI Listing
January 2010

VHL loss causes spindle misorientation and chromosome instability.

Nat Cell Biol 2009 Aug 20;11(8):994-1001. Epub 2009 Jul 20.

Institute of Cell Biology, ETH Zurich, 8093 Zurich, Switzerland.

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http://dx.doi.org/10.1038/ncb1912DOI Listing
August 2009

Homogeneous MGMT immunoreactivity correlates with an unmethylated MGMT promoter status in brain metastases of various solid tumors.

PLoS One 2009 10;4(3):e4775. Epub 2009 Mar 10.

Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0004775PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2652028PMC
June 2009

Loss of VHL and hypoxia provokes PAX2 up-regulation in clear cell renal cell carcinoma.

Clin Cancer Res 2009 May 28;15(10):3297-304. Epub 2009 Apr 28.

Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1158/1078-0432.CCR-08-2779DOI Listing
May 2009

Sporadic clear cell renal cell carcinoma but not the papillary type is characterized by severely reduced frequency of primary cilia.

Mod Pathol 2009 Jan 25;22(1):31-6. Epub 2008 Jul 25.

Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://www.nature.com/doifinder/10.1038/modpathol.2008.132
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http://dx.doi.org/10.1038/modpathol.2008.132DOI Listing
January 2009

A procedure for tissue freezing and processing applicable to both intra-operative frozen section diagnosis and tissue banking in surgical pathology.

Virchows Arch 2008 Mar;452(3):305-12

Department of Pathology, Institute of Surgical Pathology, Zurich University Hospital, Schmelzbergstrasse 12, Zurich, Switzerland.

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http://dx.doi.org/10.1007/s00428-008-0584-yDOI Listing
March 2008

Consistent expression of the stem cell renewal factor BMI-1 in primary and metastatic melanoma.

Int J Cancer 2007 Oct;121(8):1764-70

Department of Pathology, Institute of Surgical Pathology, University Hospital Zurich, Zurich, Switzerland.

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http://dx.doi.org/10.1002/ijc.22891DOI Listing
October 2007

Frequent amplifications and abundant expression of TRIO, NKD2, and IRX2 in soft tissue sarcomas.

Genes Chromosomes Cancer 2006 Sep;45(9):829-38

Division of Molecular Genetics (B060), German Cancer Research Center, Im Neuenheimer Feld 280, Heidelberg 69120, Germany.

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http://dx.doi.org/10.1002/gcc.20343DOI Listing
September 2006

Expression and amplification of therapeutic target genes in retinoblastoma.

Graefes Arch Clin Exp Ophthalmol 2005 Feb 10;243(2):156-62. Epub 2004 Nov 10.

Universitäts-Augenklinik Basel, Mittlere Strasse 91, 4056, Basel, Switzerland.

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http://link.springer.com/10.1007/s00417-004-1036-2
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http://dx.doi.org/10.1007/s00417-004-1036-2DOI Listing
February 2005

Different types of microsatellite instability in ovarian carcinoma.

Int J Cancer 2004 Nov;112(4):643-6

Institute of Pathology, University of Basel, Switzerland.

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http://dx.doi.org/10.1002/ijc.20455DOI Listing
November 2004

Molecular and clinicopathological analysis of ovarian carcinomas with and without microsatellite instability.

Anticancer Res 2004 Jan-Feb;24(1):361-9

Department of Gynecology, University of Basel, Obere, Batterieweg 39, CH-4059 Basel, Switzerland.

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May 2004

Impaired expression of the cell cycle regulator BTG2 is common in clear cell renal cell carcinoma.

Cancer Res 2004 Mar;64(5):1632-8

Institute for Pathology, University of Basel, Basel, Switzerland.

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March 2004

Relevance of nuclear and cytoplasmic von hippel lindau protein expression for renal carcinoma progression.

Am J Pathol 2003 Sep;163(3):1013-20

Institute of Pathology, University Hospital, University of Basel, Schönbeinstrasse 40, 4031 Basel, Switzerland.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1868278PMC
September 2003

Cyclin E overexpression and amplification in human tumours.

J Pathol 2003 Jul;200(3):375-82

Institute of Pathology, University Hospital, University of Basel, 4031 Basel, Switzerland.

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http://dx.doi.org/10.1002/path.1356DOI Listing
July 2003

Amplification pattern of 12q13-q15 genes (MDM2, CDK4, GLI) in urinary bladder cancer.

Oncogene 2002 Apr;21(16):2476-83

Institute for Pathology and Urologic Clinics, University of Basel, Schoenbeinstrasse 40, CH-4003 Basel, Switzerland.

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http://dx.doi.org/10.1038/sj.onc.1205304DOI Listing
April 2002