Publications by authors named "Ozlem Tastan Bishop"

56Publications

Impact of Early Pandemic Stage Mutations on Molecular Dynamics of SARS-CoV-2 M.

J Chem Inf Model 2020 Sep 16. Epub 2020 Sep 16.

Research Unit in Bioinformatics, Department of Microbiology and Biochemistry, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.1021/acs.jcim.0c00634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496595PMC
September 2020

Oral Phyto-thymol ameliorates the stress induced IBS symptoms.

Sci Rep 2020 Aug 17;10(1):13900. Epub 2020 Aug 17.

Department of Pharmaceutical Science and Chinese Traditional Medicine, Southwest University, Beibei, Chongqing, 400715, China.

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http://dx.doi.org/10.1038/s41598-020-70420-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7431530PMC
August 2020

AMBER force field parameters for the Zn (II) ions of the tunneling-fold enzymes GTP cyclohydrolase I and 6-pyruvoyl tetrahydropterin synthase.

J Biomol Struct Dyn 2020 Jul 28:1-18. Epub 2020 Jul 28.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.

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http://dx.doi.org/10.1080/07391102.2020.1796800DOI Listing
July 2020

Determining the unbinding events and conserved motions associated with the pyrazinamide release due to resistance mutations of pyrazinamidase.

Comput Struct Biotechnol J 2020 18;18:1103-1120. Epub 2020 May 18.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.

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http://dx.doi.org/10.1016/j.csbj.2020.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251373PMC
May 2020

Identification of Selective Novel Hits against Prolyl tRNA Synthetase Active Site and a Predicted Allosteric Site Using Approaches.

Int J Mol Sci 2020 May 27;21(11). Epub 2020 May 27.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/ijms21113803DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312540PMC
May 2020

Structural Characterization of Carbonic Anhydrase VIII and Effects of Missense Single Nucleotide Variations to Protein Structure and Function.

Int J Mol Sci 2020 Apr 16;21(8). Epub 2020 Apr 16.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/ijms21082764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7215520PMC
April 2020

The In Silico Prediction of Hotspot Residues that Contribute to the Structural Stability of Subunit Interfaces of a Picornavirus Capsid.

Viruses 2020 03 31;12(4). Epub 2020 Mar 31.

Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/v12040387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7232237PMC
March 2020

Understanding the Pyrimethamine Drug Resistance Mechanism via Combined Molecular Dynamics and Dynamic Residue Network Analysis.

Molecules 2020 Feb 18;25(4). Epub 2020 Feb 18.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/molecules25040904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7070769PMC
February 2020

Integrated Computational Approaches and Tools forAllosteric Drug Discovery.

Int J Mol Sci 2020 Jan 28;21(3). Epub 2020 Jan 28.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University,Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/ijms21030847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7036869PMC
January 2020

Establishing Computational Approaches Towards Identifying Malarial Allosteric Modulators: A Case Study of Hsp70s.

Int J Mol Sci 2019 Nov 8;20(22). Epub 2019 Nov 8.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/ijms20225574DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6887781PMC
November 2019

South African Abietane Diterpenoids and Their Analogs as Potential Antimalarials: Novel Insights from Hybrid Computational Approaches.

Molecules 2019 Nov 7;24(22). Epub 2019 Nov 7.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/molecules24224036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891524PMC
November 2019

Mechanism of Action of Non-Synonymous Single Nucleotide Variations Associated with -Carbonic Anhydrase II Deficiency.

Molecules 2019 Nov 4;24(21). Epub 2019 Nov 4.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/molecules24213987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6864701PMC
November 2019

Comparing sequence and structure of falcipains and human homologs at prodomain and catalytic active site for malarial peptide based inhibitor design.

Malar J 2019 May 3;18(1):159. Epub 2019 May 3.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, P.O. Box 94, Grahamstown, 6140, South Africa.

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http://dx.doi.org/10.1186/s12936-019-2790-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6500056PMC
May 2019

Modulation of Human Hsp90α Conformational Dynamics by Allosteric Ligand Interaction at the C-Terminal Domain.

Sci Rep 2019 02 7;9(1):1600. Epub 2019 Feb 7.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, 6140, South Africa.

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http://dx.doi.org/10.1038/s41598-018-35835-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367426PMC
February 2019

Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study.

Malar J 2019 Feb 6;18(1):34. Epub 2019 Feb 6.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, 6140, South Africa.

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http://dx.doi.org/10.1186/s12936-019-2665-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366043PMC
February 2019

Discorhabdin N, a South African Natural Compound, for Hsp72 and Hsc70 Allosteric Modulation: Combined Study of Molecular Modeling and Dynamic Residue Network Analysis.

Molecules 2019 Jan 6;24(1). Epub 2019 Jan 6.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://www.mdpi.com/1420-3049/24/1/188
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http://dx.doi.org/10.3390/molecules24010188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337312PMC
January 2019

Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in via Computational Structure-Based Approaches and in Vitro Inhibition Assays.

Molecules 2019 Jan 1;24(1). Epub 2019 Jan 1.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, P.O. Box 94, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.3390/molecules24010142DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337619PMC
January 2019

Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamics.

Sci Rep 2018 12 18;8(1):17938. Epub 2018 Dec 18.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, 6140, South Africa.

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http://dx.doi.org/10.1038/s41598-018-36041-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298995PMC
December 2018

MODE-TASK: large-scale protein motion tools.

Bioinformatics 2018 11;34(21):3759-3763

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.

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http://dx.doi.org/10.1093/bioinformatics/bty427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198866PMC
November 2018

Unraveling the Motions behind Enterovirus 71 Uncoating.

Biophys J 2018 02;114(4):822-838

Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2017.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984953PMC
February 2018

Homology modeling and docking of AahII-Nanobody complexes reveal the epitope binding site on AahII scorpion toxin.

Biochem Biophys Res Commun 2018 02 31;496(4):1025-1032. Epub 2018 Jan 31.

Laboratoire des Venins et Molécules Thérapeutiques, Institut Pasteur de Tunis, 13 Place Pasteur, BP74, Tunis Belvédère- University of Tunis El Manar, Tunisia; Faculté de Médecine de Tunis, 15 rue Djebel Lakhdhar, La Rabta, 1007-Université Tunis El Manar, Tunisia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S0006291X183004
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http://dx.doi.org/10.1016/j.bbrc.2018.01.036DOI Listing
February 2018

Allosteric Modulation of Human Hsp90α Conformational Dynamics.

J Chem Inf Model 2018 02 12;58(2):383-404. Epub 2018 Feb 12.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University , Grahamstown, 6140, South Africa.

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http://dx.doi.org/10.1021/acs.jcim.7b00630DOI Listing
February 2018

The generation and characterisation of neutralising antibodies against the Theiler's murine encephalomyelitis virus (TMEV) GDVII capsid reveals the potential binding site of the host cell co-receptor, heparan sulfate.

Virus Res 2018 01 16;244:153-163. Epub 2017 Nov 16.

Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2017.11.017DOI Listing
January 2018

HUMA: A platform for the analysis of genetic variation in humans.

Hum Mutat 2018 01 17;39(1):40-51. Epub 2017 Oct 17.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.

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http://dx.doi.org/10.1002/humu.23334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5722678PMC
January 2018

Improving fold resistance prediction of HIV-1 against protease and reverse transcriptase inhibitors using artificial neural networks.

BMC Bioinformatics 2017 Aug 15;18(1):369. Epub 2017 Aug 15.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, 6140, South Africa.

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http://dx.doi.org/10.1186/s12859-017-1782-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558779PMC
August 2017

MD-TASK: a software suite for analyzing molecular dynamics trajectories.

Bioinformatics 2017 Sep;33(17):2768-2771

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.1093/bioinformatics/btx349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860072PMC
September 2017

Perturbation-Response Scanning Reveals Key Residues for Allosteric Control in Hsp70.

J Chem Inf Model 2017 06 12;57(6):1359-1374. Epub 2017 Jun 12.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University , Grahamstown 6140, South Africa.

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http://dx.doi.org/10.1021/acs.jcim.6b00775DOI Listing
June 2017

Interacting motif networks located in hotspots associated with RNA release are conserved in Enterovirus capsids.

FEBS Lett 2017 06 22;591(12):1687-1701. Epub 2017 May 22.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.

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http://dx.doi.org/10.1002/1873-3468.12663DOI Listing
June 2017

Structure-Based Analysis of Single Nucleotide Variants in the Renin-Angiotensinogen Complex.

Glob Heart 2017 06 13;12(2):121-132. Epub 2017 Mar 13.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.gheart.2017.01.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5583000PMC
June 2017

Role of Structural Bioinformatics in Drug Discovery by Computational SNP Analysis: Analyzing Variation at the Protein Level.

Glob Heart 2017 06 13;12(2):151-161. Epub 2017 Mar 13.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.gheart.2017.01.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5582997PMC
June 2017

PRIMO: An Interactive Homology Modeling Pipeline.

PLoS One 2016 17;11(11):e0166698. Epub 2016 Nov 17.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, 6140, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166698PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113968PMC
June 2017

Bioinformatic characterization of type-specific sequence and structural features in auxiliary activity family 9 proteins.

Biotechnol Biofuels 2016 9;9:239. Epub 2016 Nov 9.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, 6140 South Africa.

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http://dx.doi.org/10.1186/s13068-016-0655-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5101804PMC
November 2016

Subcellular localisation of Theiler's murine encephalomyelitis virus (TMEV) capsid subunit VP1 vis-á-vis host protein Hsp90.

Virus Res 2016 08 3;222:53-63. Epub 2016 Jun 3.

Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, 6140, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.virusres.2016.06.003DOI Listing
August 2016

Structure Based Docking and Molecular Dynamic Studies of Plasmodial Cysteine Proteases against a South African Natural Compound and its Analogs.

Sci Rep 2016 Mar 31;6:23690. Epub 2016 Mar 31.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.

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http://dx.doi.org/10.1038/srep23690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4814779PMC
March 2016

The Development of Computational Biology in South Africa: Successes Achieved and Lessons Learnt.

PLoS Comput Biol 2016 Feb 4;12(2):e1004395. Epub 2016 Feb 4.

South African National Bioinformatics Institute/Medical Research Council of South Africa Bioinformatics Unit, University of the Western Cape, Bellville, South Africa.

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http://dx.doi.org/10.1371/journal.pcbi.1004395DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4742231PMC
February 2016

Human, vector and parasite Hsp90 proteins: A comparative bioinformatics analysis.

FEBS Open Bio 2015 14;5:916-27. Epub 2015 Nov 14.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.1016/j.fob.2015.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4688443PMC
January 2016

Analysis of non-peptidic compounds as potential malarial inhibitors against Plasmodial cysteine proteases via integrated virtual screening workflow.

J Biomol Struct Dyn 2016 Oct 28;34(10):2084-101. Epub 2016 Jan 28.

a Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology , Rhodes University , P.O. Box 94, Grahamstown 6140 , South Africa.

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http://dx.doi.org/10.1080/07391102.2015.1108231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5035544PMC
October 2016

JMS: An Open Source Workflow Management System and Web-Based Cluster Front-End for High Performance Computing.

PLoS One 2015 17;10(8):e0134273. Epub 2015 Aug 17.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0134273PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539224PMC
May 2016

SANCDB: a South African natural compound database.

J Cheminform 2015 19;7:29. Epub 2015 Jun 19.

Department of Biochemistry and Microbiology, Research Unit in Bioinformatics (RUBi), Rhodes University, Grahamstown, South Africa.

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http://dx.doi.org/10.1186/s13321-015-0080-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471313PMC
June 2015

Plasmodium falciparum Hop: detailed analysis on complex formation with Hsp70 and Hsp90.

Biochem Biophys Res Commun 2015 Jan 4;456(1):440-5. Epub 2014 Dec 4.

Research Unit in Bioinformatics (RUBi), Department of Biochemistry and Microbiology, Rhodes University, 6140 Grahamstown, South Africa. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2014.11.103DOI Listing
January 2015

Research capacity. Enabling the genomic revolution in Africa.

Authors:
Charles Rotimi Akin Abayomi Alash'le Abimiku Victoria May Adabayeri Clement Adebamowo Ezekiel Adebiyi Adebowale D Ademola Adebowale Adeyemo Dwomoa Adu Dissou Affolabi Godfred Agongo Samuel Ajayi Sally Akarolo-Anthony Rufus Akinyemi Albert Akpalu Marianne Alberts Orlando Alonso Betancourt Ahmed Mansour Alzohairy Gobena Ameni Olukemi Amodu Gabriel Anabwani Kristian Andersen Fatiu Arogundade Oyedunni Arulogun Danny Asogun Rasheed Bakare Naby Balde Mary Lynn Baniecki Christine Beiswanger Alia Benkahla Lara Bethke Micheal Boehnke Vincent Boima James Brandful Andrew I Brooks Frank C Brosius Chester Brown Bruno Bucheton David T Burke Barrington G Burnett Stacy Carrington-Lawrence Nadia Carstens John Chisi Alan Christoffels Richard Cooper Heather Cordell Nigel Crowther Talishiea Croxton Jantina de Vries Leslie Derr Peter Donkor Seydou Doumbia Audrey Duncanson Ivy Ekem Ahmed El Sayed Mark E Engel John C K Enyaru Dean Everett Faisal M Fadlelmola Eyitayo Fakunle Kenneth H Fischbeck Anne Fischer Onikepe Folarin Junaid Gamieldien Robert F Garry Simani Gaseitsiwe Rasheed Gbadegesin Anita Ghansah Maria Giovanni Parham Goesbeck F Xavier Gomez-Olive Donald S Grant Ravnit Grewal Mark Guyer Neil A Hanchard Christian T Happi Scott Hazelhurst Branwen J Hennig Christiane Hertz- Fowler Winston Hide Friedhelm Hilderbrandt Christopher Hugo-Hamman Muntaser E Ibrahim Regina James Yasmina Jaufeerally-Fakim Carolyn Jenkins Ute Jentsch Pan-Pan Jiang Moses Joloba Victor Jongeneel Fourie Joubert Mukthar Kader Kathleen Kahn Pontiano Kaleebu Saidi H Kapiga Samar Kamal Kassim Ishmael Kasvosve Jonathan Kayondo Bernard Keavney Adeodata Kekitiinwa Sheik Humarr Khan Paul Kimmel Mary-Claire King Robert Kleta Mathurin Koffi Jeffrey Kopp Matthias Kretzler Judit Kumuthini Samuel Kyobe Catherine Kyobutungi Daniel T Lackland Karen A Lacourciere Guida Landouré Rita Lawlor Thomas Lehner Maia Lesosky Naomi Levitt Katherine Littler Zane Lombard Jeanne F Loring Sylvester Lyantagaye Annette Macleod Ebony B Madden Chengetai R Mahomva Julie Makani Manmak Mamven Marape Marape Graeme Mardon Patricia Marshall Darren P Martin Daniel Masiga Robin Mason Michael Mate-Kole Enock Matovu Mary Mayige Bongani M Mayosi Jean Claude Mbanya Sheryl A McCurdy Mark I McCarthy Helen McIlleron S O Mc'Ligeyo Corrine Merle Ana Olga Mocumbi Charles Mondo John V Moran Ayesha Motala Marva Moxey-Mims Wata Sununguko Mpoloka Chisomo L Msefula Thuli Mthiyane Nicola Mulder Gebregziab her Mulugeta Dieuodonne Mumba John Musuku Mo Nagdee Oyekanmi Nash Daouda Ndiaye Anh Quynh Nguyen Mark Nicol Oathokwa Nkomazana Shane Norris Betty Nsangi Alexander Nyarko Moffat Nyirenda Eileen Obe Reginald Obiakor Abraham Oduro Solomon F Ofori-Acquah Okechukwu Ogah Stephen Ogendo Kwaku Ohene-Frempong Akinlolu Ojo Timothy Olanrewaju John Oli Charlotte Osafo Odile Ouwe Missi Oukem-Boyer Bruce Ovbiagele Andrew Owen Mayowa Ojo Owolabi Lukman Owolabi Ellis Owusu-Dabo Guillaume Pare Rulan Parekh Hugh G Patterton Margaret B Penno Jane Peterson Rembert Pieper Jacob Plange-Rhule Martin Pollak Julia Puzak Rajkumar S Ramesar Michele Ramsay Rebekah Rasooly Shiksha Reddy Pardis C Sabeti Kwamena Sagoe Tunde Salako Oumar Samassékou Manjinder S Sandhu Osman Sankoh Fred Stephen Sarfo Marie Sarr Gasnat Shaboodien Issa Sidibe Gustave Simo Martin Simuunza Liam Smeeth Eugene Sobngwi Himla Soodyall Hermann Sorgho Oumou Sow Bah Sudha Srinivasan Dan J Stein Ezra S Susser Carmen Swanepoel Godfred Tangwa Andrew Tareila Ozlem Tastan Bishop Bamidele Tayo Nicki Tiffin Halidou Tinto Ekaete Tobin Stephen Meir Tollman Mahamadou Traoré Marsha J Treadwell Jennifer Troyer Masego Tsimako-Johnstone Vincent Tukei Ifeoma Ulasi Nzovu Ulenga Beverley van Rooyen Ablo Prudence Wachinou Salina P Waddy Alisha Wade Misaki Wayengera James Whitworth Louise Wideroff Cheryl A Winkler Sarah Winnicki Ambroise Wonkam Mengistu Yewondwos Tadase sen Nathan Yozwiak Heather Zar

Science 2014 Jun;344(6190):1346-8

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http://dx.doi.org/10.1126/science.1251546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138491PMC
June 2014

How to establish a bioinformatics postgraduate degree programme--a case study from South Africa.

Brief Bioinform 2015 Mar 2;16(2):346-54. Epub 2014 May 2.

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http://dx.doi.org/10.1093/bib/bbu014DOI Listing
March 2015

Sequence and domain conservation of the coelacanth Hsp40 and Hsp90 chaperones suggests conservation of function.

J Exp Zool B Mol Dev Evol 2014 Sep 17;322(6):359-78. Epub 2013 Sep 17.

Department of Biochemistry, Microbiology and Biotechnology, Rhodes University Bioinformatics (RUBi), Rhodes University, Grahamstown, South Africa; Biological Sciences and Bioengineering, Faculty of Engineering and Natural Sciences, Sabanci University, Istanbul, Turkey.

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http://dx.doi.org/10.1002/jez.b.22541DOI Listing
September 2014

Plasmodium falciparum Hsp70-x: a heat shock protein at the host-parasite interface.

J Biomol Struct Dyn 2014 13;32(11):1766-79. Epub 2013 Sep 13.

a Department of Biochemistry, Microbiology and Biotechnology, Rhodes University Bioinformatics (RUBi) , Rhodes University , Grahamstown , 6140 , South Africa .

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http://dx.doi.org/10.1080/07391102.2013.834849DOI Listing
May 2015

Analysis of protein thermostability enhancing factors in industrially important thermus bacteria species.

Evol Bioinform Online 2013 18;9:327-42. Epub 2013 Aug 18.

Bioinformatics and Computational Biology Unit, Department of Biochemistry, University of Pretoria, South Africa.

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http://dx.doi.org/10.4137/EBO.S12539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3762613PMC
September 2013

Comparative structural bioinformatics analysis of Bacillus amyloliquefaciens chemotaxis proteins within Bacillus subtilis group.

Appl Microbiol Biotechnol 2011 Dec 13;92(5):997-1008. Epub 2011 Oct 13.

Department of Biochemistry, Microbiology and Biotechnology, Rhodes University Bioinformatics (RUBi), Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.1007/s00253-011-3582-yDOI Listing
December 2011

The PINIT domain of PIAS3: structure-function analysis of its interaction with STAT3.

J Mol Recognit 2011 Sep-Oct;24(5):795-803

Biomedical Biotechnology Research Unit, Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.1002/jmr.1111DOI Listing
January 2012

Study of protein complexes via homology modeling, applied to cysteine proteases and their protein inhibitors.

J Mol Model 2011 Dec 2;17(12):3163-72. Epub 2011 Mar 2.

Rhodes University Bioinformatics (RUBi), Department of Biochemistry, Microbiology and Biotechnology, Rhodes University, Grahamstown 6140, South Africa.

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http://dx.doi.org/10.1007/s00894-011-0990-yDOI Listing
December 2011

Characterization of RNA-protein interactions by phosphorothioate footprinting and its applications to the ribosome.

Methods Mol Biol 2008 ;488:129-51

Department of Biochemistry, University of Pretoria, Pretoria, South Africa.

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http://dx.doi.org/10.1007/978-1-60327-475-3_9DOI Listing
January 2009

A new approach to possible substrate binding mechanisms for nitrile hydratase.

Biochem Biophys Res Commun 2006 Apr 6;343(1):319-25. Epub 2006 Mar 6.

Department of Biotechnology, University of the Western Cape, Bellville 7535, South Africa.

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http://dx.doi.org/10.1016/j.bbrc.2006.02.150DOI Listing
April 2006