Publications by authors named "Owen M Rennert"

65Publications

Genetic correction of Werner syndrome gene reveals impaired pro-angiogenic function and HGF insufficiency in mesenchymal stem cells.

Aging Cell 2020 05 22;19(5):e13116. Epub 2020 Apr 22.

School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China.

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May 2020

Toward a Pathway-Driven Clinical-Molecular Framework for Classifying Autism Spectrum Disorders.

Pediatr Neurol 2019 09 14;98:46-52. Epub 2019 May 14.

Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.

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September 2019

Functional genomics analysis of Phelan-McDermid syndrome 22q13 region during human neurodevelopment.

PLoS One 2019 15;14(3):e0213921. Epub 2019 Mar 15.

Division of Intramural Research, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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December 2019

Barakat syndrome revisited.

Am J Med Genet A 2018 06 16;176(6):1341-1348. Epub 2018 Apr 16.

Section on Endocrinology & Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), Bethesda, Maryland.

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June 2018

Editorial: Non-Coding RNAs in Neurodevelopmental Disorders.

Front Neurol 2017 27;8:629. Epub 2017 Nov 27.

Department of Internal Medicine, University of Michigan, Ann Arbor, MI, United States.

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November 2017

Idiopathic Autism: Cellular and Molecular Phenotypes in Pluripotent Stem Cell-Derived Neurons.

Mol Neurobiol 2017 08 29;54(6):4507-4523. Epub 2016 Jun 29.

Laboratory of Clinical and Developmental Genomics, National Institute of Child Health and Human Development (NICHD), National Institutes of Health (NIH), 10 Center Drive, MSC 1255, Building 10, Room 1C-250, Bethesda, MD, 20892-1255, USA.

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August 2017

The Evolving Diagnostic and Genetic Landscapes of Autism Spectrum Disorder.

Front Genet 2016 26;7:65. Epub 2016 Apr 26.

Laboratory of Clinical and Developmental Genomics, National Institute of Child Health and Human Development, National Institutes of Health , Bethesda, MD, USA.

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May 2016

A Non-inflammatory Role for Microglia in Autism Spectrum Disorders.

Front Neurol 2016 1;7. Epub 2016 Feb 1.

National Institute of Child Health and Human Development, National Institutes of Health , Bethesda, MD , USA.

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February 2016

Shared Pathways Among Autism Candidate Genes Determined by Co-expression Network Analysis of the Developing Human Brain Transcriptome.

J Mol Neurosci 2015 Dec 23;57(4):580-94. Epub 2015 Sep 23.

Delft Bioinformatics Lab, Delft University of Technology, Delft, The Netherlands.

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December 2015

The autistic brain in the context of normal neurodevelopment.

Front Neuroanat 2015 25;9:115. Epub 2015 Aug 25.

National Institute of Child Health and Human Development, NIH Bethesda, MD, USA.

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September 2015

MicroRNA-29b/Tet1 regulatory axis epigenetically modulates mesendoderm differentiation in mouse embryonic stem cells.

Nucleic Acids Res 2015 Sep 30;43(16):7805-22. Epub 2015 Jun 30.

Reproduction, Development and Endocrinology Program, School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, N.T., Hong Kong SAR, China Shandong University (CUHK-SDU) Joint Laboratory on Reproductive Genetics, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China

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September 2015

GermlncRNA: a unique catalogue of long non-coding RNAs and associated regulations in male germ cell development.

Database (Oxford) 2015 17;2015:bav044. Epub 2015 May 17.

Reproduction, Development and Endocrinology Program, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong-Shandong University (CUHK-SDU) Joint Laboratory on Reproductive Genetics and CUHK-BGI Innovation Institute of Trans-Omics, The Chinese University of Hong Kong, Shatin, Hong Kong, China, GigaScience, Beijing Genomics Institute-Hong Kong (BGI-HK) Research Institute, 16 Dai Fu Street, Tai Po Industrial Estate, Hong Kong, China, Beijing Genomics Institute-Shenzhen (BGI-SZ), Beishan Industrial Zone, Yantian District, Shenzhen, China and The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA Reproduction, Development and Endocrinology Program, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong-Shandong University (CUHK-SDU) Joint Laboratory on Reproductive Genetics and CUHK-BGI Innovation Institute of Trans-Omics, The Chinese University of Hong Kong, Shatin, Hong Kong, China, GigaScience, Beijing Genomics Institute-Hong Kong (BGI-HK) Research Institute, 16 Dai Fu Street, Tai Po Industrial Estate, Hong Kong, China, Beijing Genomics Institute-Shenzhen (BGI-SZ), Beishan Industrial Zone, Yantian District, Shenzhen, China and The Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA Reproduction, Development and Endocrinology Program, School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong-Shandong University (CUHK-SDU) Joint Laboratory on Reproductive Genetics and CUHK-BGI Innovation Institute of Trans-Omics, The Chinese University of Hong Kong, Shatin, Hong Kong, China, GigaScience, Beijing Genomics Institute-Hong Kong (BGI-HK) Research Institute, 16 Dai Fu Street, Tai Po Industrial Estate, Hong Kong, China, Beijing Genomics Institute-Shenzhen (BGI-SZ), Beishan Industrial Zone, Yantian District, Shenzhen, China and T

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December 2015

Modulation of microRNA expression in human lung cancer cells by the G9a histone methyltransferase inhibitor BIX01294.

Oncol Lett 2014 Jun 4;7(6):1819-1825. Epub 2014 Apr 4.

Laboratory of Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-4429, USA.

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June 2014

Telomerase protects werner syndrome lineage-specific stem cells from premature aging.

Stem Cell Reports 2014 Apr 27;2(4):534-46. Epub 2014 Mar 27.

Laboratory of Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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April 2014

Long noncoding RNAs in spermatogenesis: insights from recent high-throughput transcriptome studies.

Reproduction 2014 May 8;147(5):R131-41. Epub 2014 Apr 8.

School of Biomedical Sciences, Room 622A, Lo Kwee-Seong Integrated Biomedical Sciences Building, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

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May 2014

Altered glial marker expression in autistic post-mortem prefrontal cortex and cerebellum.

Mol Autism 2014 Jan 10;5(1). Epub 2014 Jan 10.

Laboratory of Clinical and Developmental Genomics, National Institute of Child Health and Human Development, National Institutes of Health, 49 Convent Drive, Building 49, Room 2C078, Bethesda, MD 20814, USA.

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January 2014

Mapping genomic features of tiling microarray data by TileMapper.

Methods Mol Biol 2013 ;1067:225-33

Laboratory of Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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March 2014

Detection of epigenetic alterations using tiling arrays.

Methods Mol Biol 2013 ;1067:79-86

Laboratory of Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.

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March 2014

Sex-biased gene expression in the developing brain: implications for autism spectrum disorders.

Mol Autism 2013 May 7;4(1):10. Epub 2013 May 7.

National Institute of Child Health and Human Development, National Institutes of Health, 49 Convent Drive, Building 49, Room 2C08, Bethesda, MD 20814, USA.

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May 2013

Association of brain-derived neurotrophic factor (BDNF) haploinsufficiency with lower adaptive behaviour and reduced cognitive functioning in WAGR/11p13 deletion syndrome.

Cortex 2013 Nov-Dec;49(10):2700-10. Epub 2013 Feb 19.

Unit on Metabolism and Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institutes of Health, Bethesda, MD, USA; Section on Growth and Obesity, Program in Developmental Endocrinology and Genetics, NICHD, National Institutes of Health, Bethesda, MD, USA. Electronic address:

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July 2014

Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer.

Int J Cancer 2013 Jul 12;133(2):373-82. Epub 2013 Feb 12.

Laboratory of Tumor Immunology and Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA.

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July 2013

Long-term vitamin A deficiency induces alteration of adult mouse spermatogenesis and spermatogonial differentiation: direct effect on spermatogonial gene expression and indirect effects via somatic cells.

J Nutr Biochem 2013 Jun 17;24(6):1123-35. Epub 2012 Dec 17.

Laboratory of Clinical Genomics, Section on Developmental Genomics, National Institutes of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-4429, USA.

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June 2013

Aberrant expression of long noncoding RNAs in autistic brain.

J Mol Neurosci 2013 Mar 5;49(3):589-93. Epub 2012 Sep 5.

Laboratory of Clinical and Developmental Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20814, USA.

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March 2013

Integrative gene network analysis provides novel regulatory relationships, genetic contributions and susceptible targets in autism spectrum disorders.

Gene 2012 Apr 26;496(2):88-96. Epub 2012 Jan 26.

Laboratory of Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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April 2012

Methylation profiling using methylated DNA immunoprecipitation and tiling array hybridization.

Methods Mol Biol 2012 ;825:115-26

Section on Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA.

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April 2012

Identification of novel long noncoding RNA transcripts in male germ cells.

Methods Mol Biol 2012 ;825:105-14

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

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April 2012

Revealing the transcriptome landscape of mouse spermatogonial cells by tiling microarray.

Methods Mol Biol 2012 ;825:75-92

School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong, China.

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April 2012

Expression of human NAA11 (ARD1B) gene is tissue-specific and is regulated by DNA methylation.

Epigenetics 2011 Nov 1;6(11):1391-9. Epub 2011 Nov 1.

Section on Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Institutes of Health, Bethesda, MD, USA.

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November 2011

Expression profiling of autism candidate genes during human brain development implicates central immune signaling pathways.

PLoS One 2011 15;6(9):e24691. Epub 2011 Sep 15.

Laboratory of Clinical and Developmental Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, United States of America.

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February 2012

Accessing the genomic effects of naked nanoceria in murine neuronal cells.

Nanomedicine 2012 Jul 1;8(5):599-608. Epub 2011 Sep 1.

Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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July 2012

Generation of fertile sperm in a culture dish: clinical implications.

Asian J Androl 2011 Jul 6;13(4):618-9. Epub 2011 Jun 6.

Section on Clinical and Developmental Genomics, Eunice Kennedy Shriver National Institute of Child Health & Human Development, Bethesda, MD 20892, USA.

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July 2011

Methylation patterns of Brahma during spermatogenesis and oogenesis: potential implications.

Fertil Steril 2011 Jan 17;95(1):382-4. Epub 2010 Aug 17.

Laboratory of Clinical and Developmental Genomics, Program in Reproductive and Adult Endocrinology, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20814, USA.

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January 2011

GonadSAGE: a comprehensive SAGE database for transcript discovery on male embryonic gonad development.

Bioinformatics 2010 Feb 21;26(4):585-6. Epub 2009 Dec 21.

Section on Developmental Genomics, Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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February 2010

DNA methylation of cancer genome.

Birth Defects Res C Embryo Today 2009 Dec;87(4):335-50

Section on Developmental Genomics, Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland, USA.

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December 2009

Juvenile xanthogranuloma in a child with previously unsuspected neurofibromatosis type 1 and juvenile myelomonocytic leukemia.

Pediatr Blood Cancer 2010 Jan;54(1):173-5

Eunice Kennedy Shriver National Institute of Child Health and Human Development, Section on Developmental Genetics, Bethesda, MD 20892-1831, USA.

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January 2010

Two types of human malignant melanoma cell lines revealed by expression patterns of mitochondrial and survival-apoptosis genes: implications for malignant melanoma therapy.

Mol Cancer Ther 2009 May 21;8(5):1292-304. Epub 2009 Apr 21.

1Department of Biochemistry and Molecular Biology and the Catherine Birch McCormick Genomics Center, The George Washington University School of Medicine and Health Sciences, Washington, District of Columbia 20037, USA.

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May 2009

Developmental staging of male murine embryonic gonad by SAGE analysis.

J Genet Genomics 2009 Apr;36(4):215-27

Section on Developmental Genomics, Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

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April 2009

Genomic landscape of developing male germ cells.

Birth Defects Res C Embryo Today 2009 Mar;87(1):43-63

Section on Developmental Genomics, Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-4429, USA.

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March 2009

Cloning, characterization, and expression analysis of the novel acetyltransferase retrogene Ard1b in the mouse.

Biol Reprod 2009 Aug 25;81(2):302-9. Epub 2009 Feb 25.

Laboratory of Clinical Genomics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA.

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August 2009

Brain-derived neurotrophic factor and obesity in the WAGR syndrome.

N Engl J Med 2008 Aug;359(9):918-27

Unit on Growth and Obesity, Program in Developmental Endocrinology and Genetics, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892-1103, USA.

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August 2008

Dysregulated mitochondrial genes and networks with drug targets in postmortem brain of patients with posttraumatic stress disorder (PTSD) revealed by human mitochondria-focused cDNA microarrays.

Int J Biol Sci 2008 Aug 5;4(4):223-35. Epub 2008 Aug 5.

Department of Biochemistry, Molecular Biology, the Catherine Birch McCormick Genomics Center, The George Washington University School of Medicine, Health Sciences, Washington, DC 20037, USA.

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August 2008

Reducing the impact of poverty on health and human development: scientific approaches. Preface.

Ann N Y Acad Sci 2008 ;1136:xi-xii

National Institute of Child Health and Human Development, National Institute of Health, Bethesda, Maryland, USA.

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August 2008

Molecular mechanism underlying differential apoptosis between human melanoma cell lines UACC903 and UACC903(+6) revealed by mitochondria-focused cDNA microarrays.

Apoptosis 2008 Aug;13(8):993-1004

Department of Biochemistry and Molecular Biology and the Catherine Birch McCormick Genomics Center, The George Washington University School of Medicine and Health Sciences, Ross Hall, Room 555, 2300 I Street NW, Washington, DC 20037, USA.

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August 2008

Human chorionic gonadotropin induces neuronal differentiation of PC12 cells through activation of stably expressed lutropin/choriogonadotropin receptor.

Endocrinology 2007 Dec 30;148(12):5865-73. Epub 2007 Aug 30.

Section on Developmental Genomics, Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, 49 Convent Drive, MSC 4429, Bethesda, MD 20892-4429, USA.

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December 2007

Mitochondria as key components of the stress response.

Trends Endocrinol Metab 2007 Jul 17;18(5):190-8. Epub 2007 May 17.

Human Biochemical Genetics Section, MGB, NHGRI, NIH, Bethesda, MD 20892, USA.

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July 2007

BioSilico- a functional genomics platform to identify novel candidate genes from gene expression data.

AMIA Annu Symp Proc 2005 :1089

National Institute for Child Health and Human Development (NICHD), National Institutes of Health, USA.

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February 2007

Structural characterization and expression studies of Dby and its homologs in the mouse.

J Androl 2006 Sep-Oct;27(5):653-61. Epub 2006 May 25.

Laboratory of Clinical Genomics, NICHD/NIH, MSC 4429, Bethesda, MD 20892-4429, USA.

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November 2006

Biological effect of a novel mutation in the third leucine-rich repeat of human luteinizing hormone receptor.

Mol Endocrinol 2006 Oct 18;20(10):2493-503. Epub 2006 May 18.

Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Building 49, Room 2A08, 49 Convent Drive, MSC 4429, Bethesda, Maryland 20892-4429, USA.

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October 2006

Application of transcriptional and biological network analyses in mouse germ-cell transcriptomes.

Genomics 2006 Jul 4;88(1):18-33. Epub 2006 May 4.

Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Building 49, Room 2C08, 49 Convent Drive, MSC 4429, Bethesda, MD 20892-4429, USA.

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July 2006

The complexity of antisense transcription revealed by the study of developing male germ cells.

Genomics 2006 Jun 3;87(6):681-92. Epub 2006 Feb 3.

Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Building 49, Room 2A08, 49 Convent Drive, MSC 4429, Bethesda, MD 20892-4429, USA.

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June 2006

Transcriptome analyses of male germ cells with serial analysis of gene expression (SAGE).

Mol Cell Endocrinol 2006 May 18;250(1-2):8-19. Epub 2006 Jan 18.

Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, 49 Convent Drive, MSC 4429, Bethesda, MD 20892-4429, USA.

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May 2006

A novel function of differentiation revealed by cDNA microarray profiling of p75NTR-regulated gene expression.

Differentiation 2005 Oct;73(8):385-96

Department of Cell Biology, Georgetown University Medical Center, Medical Dental Building, Washington, DC 20057-1436, USA.

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October 2005

Expression profiling of purified male germ cells: stage-specific expression patterns related to meiosis and postmeiotic development.

Physiol Genomics 2006 Jan 15;24(2):75-85. Epub 2005 Nov 15.

Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892-4429, USA.

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January 2006

Rieger's anomaly and other ocular abnormalities in association with osteogenesis imperfecta and a COL1A1 mutation.

Ophthalmic Genet 2005 Sep;26(3):135-8

Pediatric Endocrinology Inter-Institute Training Program, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, Bethesda, MD 20892, USA.

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September 2005

Idiopathic intracranial hypertension in cystinosis.

J Pediatr 2004 Nov;145(5):673-8

Laboratory of Clinical Genomics, National Institute of Child Health and Development, Opthalmic Clinical Genetics Section, National Institutes of Health, Bethesda, MD 20892-4429, USA.

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November 2004

A novel missense homozygous inactivating mutation in the fourth transmembrane helix of the luteinizing hormone receptor in leydig cell hypoplasia.

Am J Med Genet A 2004 Oct;130A(2):146-53

Section on Developmental Genomics, Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 50892-4429, USA.

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October 2004

Evidence for genetic susceptibility to thrombosis in idiopathic intracranial hypertension.

Thromb Res 2003 ;111(6):389-95

Laboratory of Clinical Genomics, National Institute of Child Health and Development, National Institute of Health, MSC 4429, Bethesda, MD 20892-4429, USA.

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December 2004

Enteroviruses and type 1 diabetes mellitus.

Biomed Pharmacother 2003 Nov;57(9):379-85

Center for Drug Evaluation and Research, Food and Drug Administration, HFD-530, 5600 Fishers Lane, Rockville, MD 20857, USA.

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November 2003

Identification of differentially expressed genes in mouse spermatogenesis.

J Androl 2003 Nov-Dec;24(6):899-911

Section on Developmental Genomics, Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, NIH, USA.

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January 2004

Molecular aspects of sex differentiation.

Curr Mol Med 2002 Feb;2(1):25-37

Section on Developmental Genomics, Laboratory of Clinical Genomics, National Institute of Child Health and Human Development, NIH, Bethesda, MD, USA.

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February 2002