Owen Chan

Owen Chan

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GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2.

Gastroenterology 2019 Jun 2;156(8):2297-2312. Epub 2019 Mar 2.

Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, China. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2019.02.040DOI Listing
June 2019

Recurrent glucose deprivation leads to the preferential use of lactate by neurons in the ventromedial hypothalamus.

Am J Physiol Endocrinol Metab 2019 May 19;316(5):E948-E955. Epub 2019 Mar 19.

Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, University of Utah School of Medicine , Salt Lake City, Utah.

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http://dx.doi.org/10.1152/ajpendo.00468.2018DOI Listing
May 2019

Carvedilol prevents counterregulatory failure and impaired hypoglycaemia awareness in non-diabetic recurrently hypoglycaemic rats.

Diabetologia 2019 Apr 9;62(4):676-686. Epub 2019 Jan 9.

Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, University of Utah, Department 15 North 2030 East, EIHG Building 533, Room 2420B, Salt Lake City, UT, 84112, USA.

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http://link.springer.com/10.1007/s00125-018-4802-0
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http://dx.doi.org/10.1007/s00125-018-4802-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403018PMC
April 2019

Human papillomavirus DNA detection, p16, and oral cavity cancer in a U.S. population.

Oral Oncol 2019 Apr 5;91:92-96. Epub 2019 Mar 5.

Division of Cancer Prevention and Control, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S13688375193007
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http://dx.doi.org/10.1016/j.oraloncology.2019.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6498424PMC
April 2019

Underlying liver disease and advanced stage liver cancer are associated with elevated neutrophil-lymphocyte ratio.

Clin Mol Hepatol 2019 Apr 19. Epub 2019 Apr 19.

Cancer Center, University of Hawaii, Honolulu, HI, USA.

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http://dx.doi.org/10.3350/cmh.2019.0004DOI Listing
April 2019

IMPAIRED AWARENESS OF HYPOGLYCEMIA CONTINUES TO BE A RISK FACTOR FOR SEVERE HYPOGLYCEMIA DESPITE THE USE OF CONTINUOUS GLUCOSE MONITORING SYSTEM IN TYPE 1 DIABETES.

Endocr Pract 2019 Mar 13. Epub 2019 Mar 13.

From: 1Division of Endocrinology, Metabolism and Diabetes, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT.

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http://dx.doi.org/10.4158/EP-2018-0527DOI Listing
March 2019

Effectiveness of two different dose administration regimens of an IL-15 superagonist complex (ALT-803) in an orthotopic bladder cancer mouse model.

J Transl Med 2019 Jan 17;17(1):29. Epub 2019 Jan 17.

Translational and Clinical Research Program, University of Hawaii Cancer Center, 701 Ilalo Street Suite 353, Honolulu, HI, 96813, USA.

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http://dx.doi.org/10.1186/s12967-019-1778-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337786PMC
January 2019

Insulin regulates GLUT4 in the ventromedial hypothalamus to restore the sympathoadrenal response to hypoglycemia in diabetic rats.

Am J Physiol Endocrinol Metab 2018 Dec 18;315(6):E1286-E1295. Epub 2018 Sep 18.

Division of Endocrinology, Metabolism, and Diabetes, University of Utah School of Medicine , Salt Lake City, Utah.

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https://www.physiology.org/doi/10.1152/ajpendo.00324.2018
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http://dx.doi.org/10.1152/ajpendo.00324.2018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336954PMC
December 2018

Mammographic density and breast tissue expression of inflammatory markers, growth factors, and vimentin.

BMC Cancer 2018 Nov 29;18(1):1191. Epub 2018 Nov 29.

University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, HI, 96813, USA.

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http://dx.doi.org/10.1186/s12885-018-5088-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6267911PMC
November 2018

Hyperactivation of the hypothalamo-pituitary-adrenocortical axis in streptozotocin-diabetic gerbils (Gerbillus gerbillus).

Int J Exp Pathol 2018 08;99(4):172-179

Department of Biology and Physiology of Organisms (LBPO), Nutrition-Metabolism/FSB/USTHB, Algiers, Algeria.

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http://dx.doi.org/10.1111/iep.12284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157299PMC
August 2018

Noradrenergic Activity in the Human Brain: A Mechanism Supporting the Defense Against Hypoglycemia.

J Clin Endocrinol Metab 2018 06;103(6):2244-2252

Department of Internal Medicine, Section of Endocrinology, Yale University School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.1210/jc.2017-02717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456998PMC
June 2018

PET/CT with F Fluorocholine as an Imaging Biomarker for Chronic Liver Disease: A Preliminary Radiopathologic Correspondence Study in Patients with Liver Cancer.

Radiology 2018 04 9;287(1):294-302. Epub 2018 Jan 9.

From the Hamamatsu/Queen's PET Imaging Center (S.A.K.) and Liver Center (S.K., N.T.), The Queen's Medical Center, 1301 Punchbowl St, Honolulu, HI 96813; Departments of Medicine and Surgery, University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii (S.A.K., L.W.); and Department of Pathology, University of Hawaii Cancer Center, Honolulu, Hawaii (O.T.M.C.).

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http://dx.doi.org/10.1148/radiol.2018171333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860972PMC
April 2018

Sphingosine kinase 1 expression enhances colon tumor growth.

J Transl Med 2017 06 6;15(1):120. Epub 2017 Jun 6.

Cancer Biology Program, University of Hawaii Cancer Center, 701 Ilalo Street, Honolulu, HI, 96813, USA.

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http://dx.doi.org/10.1186/s12967-017-1220-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460497PMC
June 2017

Inhibition of glycine transporter-1 in the dorsal vagal complex improves metabolic homeostasis in diabetes and obesity.

Nat Commun 2016 11 22;7:13501. Epub 2016 Nov 22.

Toronto General Hospital Research Institute and Department of Medicine, UHN, Toronto, Ontario, Canada M5G 1L7.

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http://dx.doi.org/10.1038/ncomms13501DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5121412PMC
November 2016

Metabolic characteristics distinguishing intrahepatic cholangiocarcinoma: a negative pilot study of (18)F-fluorocholine PET/CT clarified by transcriptomic analysis.

Am J Nucl Med Mol Imaging 2016 28;6(1):73-83. Epub 2016 Jan 28.

Cancer Biology Program, The University of Hawaii Cancer Center Honolulu, Hawaii, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4749506PMC
April 2016

Chronic Liver Disease and the Detection of Hepatocellular Carcinoma by [(18)F]fluorocholine PET/CT.

Diagnostics (Basel) 2015 ;5(2):189-99

Affiliated Clinical Research Departments, The Queen's Medical Center, Honolulu, HI 96813, USA.

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http://dx.doi.org/10.3390/diagnostics5020189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469073PMC
February 2016

Immunohistological analysis of ABCD3 expression in Caucasian and African American prostate tumors.

Biomed Res Int 2015 31;2015:132981. Epub 2015 Jan 31.

Department of Biology and Center for Cancer Research, Tuskegee University, Tuskegee, AL 36088, USA.

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http://dx.doi.org/10.1155/2015/132981DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329846PMC
January 2016

A multiplex immunoassay for the non-invasive detection of bladder cancer.

J Transl Med 2016 Jan 30;14:31. Epub 2016 Jan 30.

University of Hawaii Cancer Center, 701 Ilalo St, Rm 327, Honolulu, HI, 96813, USA.

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http://dx.doi.org/10.1186/s12967-016-0783-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4736707PMC
January 2016

Reduction in SGLT1 mRNA Expression in the Ventromedial Hypothalamus Improves the Counterregulatory Responses to Hypoglycemia in Recurrently Hypoglycemic and Diabetic Rats.

Diabetes 2015 Oct 30;64(10):3564-72. Epub 2015 Jun 30.

Department of Internal Medicine, Section of Endocrinology, Yale School of Medicine, New Haven, CT

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http://dx.doi.org/10.2337/db15-0022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4587643PMC
October 2015

Posttranscriptional regulation of adrenal TH gene expression contributes to the maladaptive responses triggered by insulin-induced recurrent hypoglycemia.

Physiol Rep 2015 Feb 22;3(2). Epub 2015 Feb 22.

Division of Newborn Medicine, Departments of Pediatrics, Biochemistry and Molecular Biology, New York Medical College, Valhalla, New York.

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http://dx.doi.org/10.14814/phy2.12307DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393213PMC
February 2015

Partial blockade of nicotinic acetylcholine receptors improves the counterregulatory response to hypoglycemia in recurrently hypoglycemic rats.

Am J Physiol Endocrinol Metab 2014 Oct 12;307(7):E580-8. Epub 2014 Aug 12.

Division of Newborn Medicine, Departments of Pediatrics, Biochemistry, and Molecular Biology, New York Medical College, Valhalla, New York;

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http://dx.doi.org/10.1152/ajpendo.00237.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4250232PMC
October 2014

Is there cross talk between portal and hypothalamic glucose-sensing circuits?

Diabetes 2014 Aug;63(8):2617-9

Department of Internal Medicine-Section of Endocrinology, Yale University School of Medicine, New Haven, CT

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http://dx.doi.org/10.2337/db14-0755DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876743PMC
August 2014

Hypothalamic prolyl endopeptidase (PREP) regulates pancreatic insulin and glucagon secretion in mice.

Proc Natl Acad Sci U S A 2014 Aug 28;111(32):11876-81. Epub 2014 Jul 28.

Departments of Obstetrics, Gynecology, and Reproductive Sciences,Program in Integrative Cell Signaling and Neurobiology of Metabolism,Section of Comparative Medicine, Yale University School of Medicine, New Haven, CT 06520;Neurobiology,

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http://dx.doi.org/10.1073/pnas.1406000111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4136568PMC
August 2014

Immunohistochemical stains of proliferating cell nuclear antigen, insulin-like growth factor 2 and clusterin help distinguish malignant from benign liver nodular lesions.

J Clin Pathol 2014 Jun 9;67(6):464-9. Epub 2014 Jan 9.

Department of Pathology and Laboratory Medicine, University of California in Los Angeles, Los Angeles, California, USA.

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http://jcp.bmj.com/lookup/doi/10.1136/jclinpath-2013-201907
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http://dx.doi.org/10.1136/jclinpath-2013-201907DOI Listing
June 2014

Lactate-induced release of GABA in the ventromedial hypothalamus contributes to counterregulatory failure in recurrent hypoglycemia and diabetes.

Diabetes 2013 Dec 12;62(12):4239-46. Epub 2013 Aug 12.

Section of Endocrinology, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.

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http://dx.doi.org/10.2337/db13-0770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3837027PMC
December 2013

Influence of VMH fuel sensing on hypoglycemic responses.

Trends Endocrinol Metab 2013 Dec 21;24(12):616-24. Epub 2013 Sep 21.

Yale University School of Medicine, Department of Internal Medicine, Section of Endocrinology, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1016/j.tem.2013.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3909530PMC
December 2013

Viral hepatitis markers in liver tissue in relation to serostatus in hepatocellular carcinoma.

Cancer Epidemiol Biomarkers Prev 2013 Nov 27;22(11):2016-23. Epub 2013 Aug 27.

Authors' Affiliations: University of Hawaii Cancer Center; The Queen's Medical Center; University of Hawaii John A. Burns School of Medicine, Honolulu, Hawaii; Division of Cancer Epidemiology and Genetics, and Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, Maryland.

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http://dx.doi.org/10.1158/1055-9965.EPI-13-0397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3818344PMC
November 2013

Smoothelin expression in the gastrointestinal tract: implication in colonic inertia.

Appl Immunohistochem Mol Morphol 2013 Oct;21(5):452-9

*Department of Pathology and Laboratory Medicine ∥Gastrointestinal Motility Program, Division of Gastroenterology, Cedars-Sinai Medical Center ¶Department of Pathology & Laboratory Medicine, University of California, Los Angeles, Los Angeles, CA †Department of Anatomical Pathology, Cleveland Clinic Foundation, Cleveland, OH ‡Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY §Department of Pathology, University of Chicago Hospitals, Chicago, IL.

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http://dx.doi.org/10.1097/PAI.0b013e31827387c9DOI Listing
October 2013

Evaluation of peripapillary lymphocytosis and lymphocytic esophagitis in adult inflammatory bowel disease.

Gastroenterol Hepatol (N Y) 2013 Aug;9(8):505-11

Dr. Benjamin Basseri is a Gastroenterologist affiliated with the Gl Motility Program at Cedars-Sinai Medical Center in Los Angeles, California. Dr. Vasiliauskas is the Associate Clinical Director of the Inflammatory Bowel Disease Center at Cedars-Sinai Medical Center. Dr. Chan is a Pathologist and Assistant Clinical Professor at the University of Hawaii in Honolulu, Hawaii. Dr. Wang is a Gastrointestinal Pathologist at the University of California, Los Angeles (UCLA) Medical Center in Los Angeles, California. Dr. Robert J. Basseri is a Gastroenterology Fellow at Loma Linda University in Loma Linda, California. Dr. Pimentel is the Director of the Gl Motility Program at Cedars-Sinai Medical Center. Dr. Soffer is a Professor of Clinical Medicine at the Keck School of Medicine at the University of Southern California in Los Angeles, California. Dr. Conklin is the Director of the Center for Esophageal Diseases at the UCLA Medical Center.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3980993PMC
August 2013

Hypothalamic regulation of glucose-stimulated insulin secretion.

Diabetes 2012 Mar;61(3):564-5

Department of Internal Medicine, Section of Endocrinology, Yale School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.2337/db11-1846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3282803PMC
March 2012

Autoimmune pancreatitis in an Asian-dominant American population.

Hawaii J Med Public Health 2012 Jan;71(1):13-8

Hawaii Medical Center - East, Honolulu, HI, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3298434PMC
January 2012

Modulation of β-adrenergic receptors in the ventromedial hypothalamus influences counterregulatory responses to hypoglycemia.

Diabetes 2011 Dec 19;60(12):3154-8. Epub 2011 Oct 19.

Department of Internal Medicine and Endocrinology, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db11-04
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http://dx.doi.org/10.2337/db11-0432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219955PMC
December 2011

Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain.

Am J Physiol Endocrinol Metab 2011 Nov 9;301(5):E978-83. Epub 2011 Aug 9.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1152/ajpendo.00304.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774165PMC
November 2011

Injection site pseudosarcoma in piriformis syndrome.

Histopathology 2011 Aug;59(2):327-32

Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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http://dx.doi.org/10.1111/j.1365-2559.2011.03933.xDOI Listing
August 2011

Lack of HER2 overexpression and amplification in small intestinal adenocarcinoma.

Am J Clin Pathol 2010 Dec;134(6):880-5

Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA.

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https://academic.oup.com/ajcp/article-lookup/doi/10.1309/AJC
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http://dx.doi.org/10.1309/AJCPK6QHNNOEMJIMDOI Listing
December 2010

Influence of insulin in the ventromedial hypothalamus on pancreatic glucagon secretion in vivo.

Diabetes 2010 Jun 18;59(6):1521-7. Epub 2010 Mar 18.

Department of Internal Medicine, Division of Endocrinology and Metabolism, Yale University School of Medicine, New Haven, Connecticut, USA.

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http://dx.doi.org/10.2337/db10-0014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2874714PMC
June 2010

Glucose prevents the fall in ventromedial hypothalamic GABA that is required for full activation of glucose counterregulatory responses during hypoglycemia.

Am J Physiol Endocrinol Metab 2010 May 9;298(5):E971-7. Epub 2010 Feb 9.

Section of Endocrinology, Department of Internal Medicine, Yale University School of Medicine, 300 Cedar St., New Haven, CT, USA.

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http://dx.doi.org/10.1152/ajpendo.00749.2009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2867375PMC
May 2010

Up-regulation of crystallins is involved in the neuroprotective effect of wolfberry on survival of retinal ganglion cells in rat ocular hypertension model.

J Cell Biochem 2010 May;110(2):311-20

Laboratory of Neurodegenerative Diseases, Department of Anatomy, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China.

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http://dx.doi.org/10.1002/jcb.22539DOI Listing
May 2010

Comprehensive and efficient HBB mutation analysis for detection of beta-hemoglobinopathies in a pan-ethnic population.

Am J Clin Pathol 2010 May;133(5):700-7

Dept of Pathology, Stanford University School of Medicine, 300 Pasteur Dr, Lane 235, Stanford, CA 94305-5324, USA.

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http://dx.doi.org/10.1309/AJCP7HQ2KWGHECIODOI Listing
May 2010

The effect of long-term insulin treatment with and without antecedent hypoglycemia on neuropeptide and corticosteroid receptor expression in the brains of diabetic rats.

Brain Res Bull 2008 Oct 29;77(4):149-57. Epub 2008 Jul 29.

University of Toronto - Department of Physiology, Medical Sciences Building, 1 King's College Circle, Toronto, ON M5S 1A8, Canada.

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http://dx.doi.org/10.1016/j.brainresbull.2008.07.001DOI Listing
October 2008

Effect of acute and recurrent hypoglycemia on changes in brain glycogen concentration.

Endocrinology 2008 Apr 10;149(4):1499-504. Epub 2008 Jan 10.

Department of Internal Medicine, Section of Endocrinology, Yale University School of Medicine, New Haven, CT 06520, USA.

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http://dx.doi.org/10.1210/en.2007-1252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2276713PMC
April 2008

Laminin 5 expression in metaplastic breast carcinomas.

Am J Surg Pathol 2008 Mar;32(3):345-53

The Department of Pathology and Laboratory Medicine, The University of California, Orange, CA 92868, USA.

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http://dx.doi.org/10.1097/PAS.0b013e3181592201DOI Listing
March 2008

Type 1 corticotropin-releasing factor receptors in the ventromedial hypothalamus promote hypoglycemia-induced hormonal counterregulation.

Am J Physiol Endocrinol Metab 2007 Sep 19;293(3):E705-12. Epub 2007 Jun 19.

Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA.

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http://dx.doi.org/10.1152/ajpendo.00136.2007DOI Listing
September 2007

ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia.

Diabetes 2007 Apr 24;56(4):1120-6. Epub 2007 Jan 24.

Yale University School of Medicine, Department of Internal Medicine, Section of Endocrinology, 300 Cedar St., TAC S141, New Haven, CT, USA.

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http://dx.doi.org/10.2337/db06-1102DOI Listing
April 2007

A retrospective analysis of placentas from twin pregnancies derived from assisted reproductive technology.

Twin Res Hum Genet 2007 Apr;10(2):385-93

Department of Pathology, University of California, San Diego Medical Center, San Diego, CA 92103-8321, USA.

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http://www.journals.cambridge.org/abstract_S1832427400007945
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http://dx.doi.org/10.1375/twin.10.2.385DOI Listing
April 2007

The additive effects of hepatitis C infection and end-stage renal disease in porphyria cutanea tarda.

Cutis 2006 Dec;78(6):397-400

University of Hawaii, Honolulu, HI, USA.

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December 2006

Chip electrophoresis as a method for quantifying total microalbuminuria.

Clin Chem 2006 Nov 21;52(11):2141-6. Epub 2006 Sep 21.

Department of Pathology, VA San Diego Healthcare System 92161, and University of California, San Diego School of Medicine, La Jolla, CA, USA.

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http://dx.doi.org/10.1373/clinchem.2006.072801DOI Listing
November 2006

Hamartomatous polyps of the colon: ganglioneuromatous, stromal, and lipomatous.

Arch Pathol Lab Med 2006 Oct;130(10):1561-6

Department of Pathology, University of California-San Diego and VA Medical Center, San Diego, Calif, USA.

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http://dx.doi.org/10.1043/1543-2165(2006)130[1561:HPOTCG]2.0.CO;2DOI Listing
October 2006

Activation of AMP-activated protein kinase within the ventromedial hypothalamus amplifies counterregulatory hormone responses in rats with defective counterregulation.

Diabetes 2006 Jun;55(6):1755-60

Department of Internal Medicine and Encocrinology, Yale University School of Medicine, P.O. Box 208020, New Haven, CT 06520-8020, USA.

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http://dx.doi.org/10.2337/db05-1359DOI Listing
June 2006

Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia.

Diabetes 2006 Apr;55(4):1080-7

Yale University School of Medicine, Department of Internal Medicine, Section of Endocrinology, 300 Cedar St., New Haven, CT 06519-1612, USA.

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http://dx.doi.org/10.2337/diabetes.55.04.06.db05-0958DOI Listing
April 2006

Changes in basal hypothalamo-pituitary-adrenal activity during exercise training are centrally mediated.

Am J Physiol Regul Integr Comp Physiol 2005 Nov;289(5):R1360-71

School of Kinesiology and Health Science, York University, 4700 Keele St., Toronto, Ontario, Canada M3J 1P3.

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http://dx.doi.org/10.1152/ajpregu.00103.2005DOI Listing
November 2005

Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats.

Diabetes 2005 Nov;54(11):3169-74

Department of Internal Medicine and Endocrinology, Yale University School of Medicine, Section of Endocrinology, P.O. Box 208020, New Haven, CT 06520-8020, USA.

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http://dx.doi.org/10.2337/diabetes.54.11.3169DOI Listing
November 2005

Hyperglycemia does not increase basal hypothalamo-pituitary-adrenal activity in diabetes but it does impair the HPA response to insulin-induced hypoglycemia.

Am J Physiol Regul Integr Comp Physiol 2005 Jul 17;289(1):R235-46. Epub 2005 Mar 17.

Department of Physiology, 1 King's College Circle, Medical Sciences Bldg. Rm. 3358, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1152/ajpregu.00674.2004DOI Listing
July 2005

Insulin alone increases hypothalamo-pituitary-adrenal activity, and diabetes lowers peak stress responses.

Endocrinology 2005 Mar 24;146(3):1382-90. Epub 2004 Nov 24.

Department of Physiology, University of Toronto, Medical Sciences Building, Room 3240, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1210/en.2004-0607DOI Listing
March 2005

Effects of diabetes and recurrent hypoglycemia on the regulation of the sympathoadrenal system and hypothalamo-pituitary-adrenal axis.

Am J Physiol Endocrinol Metab 2005 Feb 19;288(2):E422-9. Epub 2004 Oct 19.

Department of Physiology, University of Toronto, Medical Sciences Bldg., Rm. 3358, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8.

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http://dx.doi.org/10.1152/ajpendo.00389.2004DOI Listing
February 2005

Prevention of renal damage in murine lupus nephritis by CTLA-4Ig and cyclophosphamide.

Arthritis Rheum 2004 May;50(5):1539-48

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http://dx.doi.org/10.1002/art.20147DOI Listing
May 2004

The cockroach as a host for Trichinella and Enterobius vermicularis: implications for public health.

Hawaii Med J 2004 Mar;63(3):74-7

Department of Pathology, The John A. Burns School of Medicine, University of Hawaii, Honolulu, HI 96822, USA.

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March 2004

Effects of recurrent hyperinsulinemia with and without hypoglycemia on counterregulation in diabetic rats.

Am J Physiol Endocrinol Metab 2002 Jun;282(6):E1369-79

Department of Physiology, University of Toronto, Toronto, Ontario, Canada, M5S 1A8.

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http://dx.doi.org/10.1152/ajpendo.00480.2001DOI Listing
June 2002