Publications by authors named "Othon Lalos"

8 Publications

  • Page 1 of 1

Female urinary incontinence: patient-reported outcomes 1 year after midurethral sling operations.

Int Urogynecol J 2012 Oct 20;23(10):1353-9. Epub 2012 Apr 20.

Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, 901 85 Umeå, Sweden.

Introduction And Hypothesis: Although midurethral slings have become standard surgical methods to treat stress urinary incontinence (SUI), little is known about women who still have urinary incontinence (UI) after surgery. This study assesses and compares the patient-reported outcome 12 months after tension-free vaginal tape (TVT), tension-free vaginal tape-obturator (TVT-O), and transobturator tape (TOT), with a special focus on women who still have urinary leakage postoperatively.

Methods: This study analyzed preoperative and 12-month postoperative data from 3,334 women registered in the Swedish National Quality Register for Gynecological Surgery.

Results: Among the women operated with TVT (n = 2,059), TVT-O (n = 797), and TOT (n = 478), 67 %, 62 %, and 61 %, respectively, were very satisfied with the result at the 1-year follow-up. There was a significantly higher chance of becoming continent after TVT compared with TOT. In total, 977 women (29 %) still had some form of urinary leakage postoperatively. Among the postoperatively incontinent women who expressed a negative impact of UI on family, social, work, and sexual life preoperatively, considerably fewer reported a negative impact in all domains after surgery. Of those in the postoperatively incontinent group who had coital incontinence preoperatively, 63 % reported a cure of coital incontinence.

Conclusions: The proportion of women very satisfied with the result of the operation did not differ between the three groups. TVT had a higher SUI cure rate than did TOT. Despite urinary leakage 1-year postoperatively, half of the women were satisfied with the result of the operation.
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http://dx.doi.org/10.1007/s00192-012-1752-9DOI Listing
October 2012

How do urinary incontinence and urgency affect women's sexual life?

Acta Obstet Gynecol Scand 2011 Jun 15;90(6):621-8. Epub 2011 Apr 15.

Clinical Sciences, Obstetrics and Gynecology Mathematics and Mathematical Statistics, Umeå University, Umeå, Sweden.

Objective: To investigate the impact of urinary incontinence and urgency on women's sexual life and the prevalence of urinary leakage during sexual activity. A further aim was to explore factors affecting sexual desire and satisfaction with sexual life.

Design: A semi-structured questionnaire study.

Setting And Sample: Sexually active women (n=147) aged 18-74years with urinary incontinence and urgency were recruited from four outpatient clinics.

Methods: The women completed questionnaires concerning medical history, psychosocial situation, partner relationship and sexual life, and answered the Bristol Female Lower Urinary Tract Symptoms questionnaire. All underwent clinical evaluation.

Main Outcome Measures: Prevalence of urinary leakage during sexual activity, factors affecting sexual desire and sexual satisfaction.

Results: The vast majority considered sexuality to be important in their lives. One-third of the women had urinary leakage during sexual activity. Half reported that sexual life was more or less spoiled due to their urinary incontinence or urgency and they were worried about having urinary leakage during intercourse, and almost two-thirds worried about odor and felt unattractive. The women's dissatisfaction with sexual life was strongly correlated to unsatisfying psychological health, orgasmic disability and worry about urinary leakage during intercourse. Insufficient vaginal lubrication, unsatisfying psychological health and their partners' ill health were significantly correlated with decreased sexual desire.

Conclusions: Urinary incontinence and urgency have a negative impact on women's sexual life. Thus, a dialogue about sexual function in women with urinary symptoms should become an integral component in clinical management.
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http://dx.doi.org/10.1111/j.1600-0412.2011.01120.xDOI Listing
June 2011

Impact of female urinary incontinence and urgency on women's and their partners' sexual life.

Neurourol Urodyn 2011 Sep 23;30(7):1276-80. Epub 2011 Feb 23.

Department of Clinical Sciences, Obstetrics and Gynaecology, Umeå University, Umeå, Sweden.

Aims: To assess the impact of female urinary incontinence (UI) and urgency on women's and their partners' sexual life in sexually active couples and to elucidate the concordance of answers within couples.

Methods: Women aged 18-74 years with UI and/or urgency (n = 206) were consecutively recruited from four outpatient clinics. Those with a partner (n = 170) completed a questionnaire regarding relationship and sexual life and gave a similar questionnaire to him. The present paper focuses on 99 couples with an active sexual life.

Results: Twenty-two percent of the men and 43% of the women stated that the female urinary symptoms impaired their sexual life. Forty-nine percent of the women expressed worries about having urinary leakage during sexual activity, but most of their men, 94%, did not. Twenty-three percent of the men and 39% of the women responded that the woman leaked urine during sexual activity. The majority, 84%, of women considered this a problem, but 65% of their partners did not. Except for this disparity, the rest of the answers were significant concordant within the couples.

Conclusions: Female UI and urgency negatively affected sexual life in almost half of the women and in every fifth partner. A need for information and advice concerning sexual issues due to the woman's urinary disorder was found in one fifth of the couples. The majority of women with urinary leakage during sexual activities considered this as a problem, but most of their partners did not. Overall, the concordance of the answers within the couples was high.
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http://dx.doi.org/10.1002/nau.21039DOI Listing
September 2011

Urinary, climacteric and sexual symptoms 1 year after treatment of cervical cancer without brachytherapy.

J Psychosom Obstet Gynaecol 2009 Dec;30(4):269-74

Department of Clinical Sciences, Obstetrics and Gynecology, University Hospital, SE-901 85 Umeå, Sweden.

Objective: Prospective studies elucidating the impact of the treatment of cervical cancer on urinary and climacteric symptoms and sexual life are relatively rare. The aim of this study was to seek information about the occurrence of urinary, climacteric and sexual symptoms in women with cervical cancer before and 1 year after treatment without brachytherapy.

Methods: This prospective study evaluated 39 women treated for cervical cancer. Data were collected by two questionnaires (before and 1 year after treatment). In order to supplement the data from the questionnaires, some data were selected from the patient's medical records.

Results: The number of voluntary micturitions, urgency, urinary incontinence and climacteric symptoms had not increased 1 year after treatment. Vaginal dryness and dyspareunia had increased and sexual desire was reduced 1-year post-treatment.

Conclusion: This study has shown that urinary and climacteric symptoms are not frequent 1 year after treatment of cervical cancer without brachytherapy. However, there is an increased occurrence of vaginal dryness and sexual disorders 1-year post-treatment, mainly in the form of dyspareunia and reduced sexual desire. Taken together these symptoms affect the women's quality of life and it is, therefore, crucial that the medical providers become more aware of and skilled to deal with these conditions before and after treatment.
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http://dx.doi.org/10.3109/01674820902789225DOI Listing
December 2009

The impact of female urinary incontinence and urgency on quality of life and partner relationship.

Neurourol Urodyn 2009 ;28(8):976-81

Department of Clinical Sciences, Obstetrics and Gynaecology, Umeå University, Umeå, Sweden.

Aims: To examine the impact of female urinary incontinence, urgency and frequency on quality of life, and partner relationship in women (18-74 years) and their partners, and make comparisons with the corresponding age groups in a Swedish population-based study.

Methods: Women with urinary incontinence, urgency and frequency (n = 206) completed specific questionnaires concerning medical history and the Bristol Female Lower Urinary Tract Symptoms questionnaire. Women who had a stable relationship (n = 170) also answered a questionnaire regarding psychosocial situation, partner relationship and sexual life, and were asked to give a similar questionnaire to their partner. Totally, 109 partners participated.

Results: The vast majority of the women considered that their urinary problems affected their physical activities negatively and almost half reported negative consequences for social life and joint activities. One third of both women and men experienced a negative impact on their relationship and about every fifth felt it had a harmful influence on physical proximity, intimacy, affection, and warmth. Compared to the older women, the younger were less satisfied with their psychological health, sexual life, leisure and financial situation, and compared to the younger men, the young women were less content with their somatic health. Overall, women with urinary problems and their partners were less satisfied with their somatic health than the corresponding age groups in the national population-based study.

Conclusions: Female urinary incontinence, urgency and frequency significantly impair the quality of life in both younger and older women, and also have negative effects on the partner relationship and the partner's life.
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http://dx.doi.org/10.1002/nau.20709DOI Listing
March 2010

[Calculi formation in female urethral diverticula. Extremely rare--but can be the cause of recurrent urinary tract infections].

Lakartidningen 2004 Apr;101(14):1290-1

Kvinnokliniken, Norrlands Universitetssjukhus, Umeå.

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April 2004

Efficacy of desmopressin (Minirin) in the treatment of nocturia: a double-blind placebo-controlled study in women.

Am J Obstet Gynecol 2003 Oct;189(4):1106-13

Department of Gynecology, Glostrup Hospital, Glostrup, Denmark.

Objective: The purpose of this study was to investigate the efficacy and safety of oral desmopressin in the treatment of nocturia in women.

Study Design: Women aged 18 years or older with nocturia (>or=2 voids per night with a nocturia index score >1) received desmopressin (0.1 mg, 0.2 mg, or 0.4 mg) during a 3-week dose-titration period. After a 1-week washout period, patients who responded in this period received desmopressin or placebo in a double-blind fashion for 3 weeks.

Results: In double-blind phase, 144 patients were randomly assigned to groups (desmopressin, n=72; placebo, n=72). For desmopressin, 33 (46%) patients had a 50% or greater reduction in nocturnal voids against baseline levels compared with 5 (7%) patients receiving placebo (P<.0001). The mean number of nocturnal voids, duration of sleep until the first nocturnal void, nocturnal diuresis, and ratios of nocturnal per 24 hours and nocturnal per daytime urine volumes changed significantly in favor of desmopressin versus placebo (P<.0001). In the dose-titration phase headache (22%), nausea (8%), and hyponatremia (6%) were reported. Two deaths occurred, although neither could be directly associated with the study drug.

Conclusion: Oral desmopressin is an effective and well-tolerated treatment for nocturia in women.
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http://dx.doi.org/10.1067/s0002-9378(03)00593-3DOI Listing
October 2003