Osvaldo Grana

Osvaldo Grana

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Osvaldo Grana

Osvaldo Grana

Publications by authors named "Osvaldo Grana"

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41Publications

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Bicycle: a bioinformatics pipeline to analyze bisulfite sequencing data.

Bioinformatics 2018 04;34(8):1414-1415

Departamento de Informática. ESEI-Escuela Superior de Ingeniería Informática, Edificio Politécnico, Campus Universitario As Lagoas S/N, Universidade de Vigo, 32004 Ourense, Spain.

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http://dx.doi.org/10.1093/bioinformatics/btx778DOI Listing
April 2018

Genomic and Molecular Screenings Identify Different Mechanisms for Acquired Resistance to MET Inhibitors in Lung Cancer Cells.

Mol Cancer Ther 2017 07 10;16(7):1366-1376. Epub 2017 Apr 10.

Genes and Cancer Group, Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute-IDIBELL, Hospitalet de Llobregat, Barcelona, Spain.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-0104DOI Listing
July 2017

Inactivation of Capicua in adult mice causes T-cell lymphoblastic lymphoma.

Genes Dev 2017 07 21;31(14):1456-1468. Epub 2017 Aug 21.

Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain.

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http://dx.doi.org/10.1101/gad.300244.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5588927PMC
July 2017

Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation.

J Exp Med 2017 05 29;214(5):1387-1409. Epub 2017 Mar 29.

Genes, Development and Disease Group, Cancer Cell Biology Programme, Spanish National Cancer Research Centre (CNIO), E-28029 Madrid, Spain

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http://dx.doi.org/10.1084/jem.20160935DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5413325PMC
May 2017

Hepatocellular Carcinomas Originate Predominantly from Hepatocytes and Benign Lesions from Hepatic Progenitor Cells.

Cell Rep 2017 04;19(3):584-600

Cancer Cell Biology Programme, Growth Factors, Nutrients and Cancer Group, Centro Nacional de Investigaciones Oncológicas (CNIO), Madrid 28029, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2017.03.059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409928PMC
April 2017

NSD2 contributes to oncogenic RAS-driven transcription in lung cancer cells through long-range epigenetic activation.

Sci Rep 2016 09 8;6:32952. Epub 2016 Sep 8.

CNIO-Lilly Epigenetics Laboratory, Spanish National Cancer Research Center (CNIO), C/ Melchor Fernández Almagro, 3. 28029 Madrid, Spain.

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http://dx.doi.org/10.1038/srep32952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015087PMC
September 2016

Telomeric RNAs are essential to maintain telomeres.

Nat Commun 2016 08 17;7:12534. Epub 2016 Aug 17.

Telomeres and Telomerase Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), 28029 Madrid, Spain.

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http://dx.doi.org/10.1038/ncomms12534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4992061PMC
August 2016

MYC/PGC-1α Balance Determines the Metabolic Phenotype and Plasticity of Pancreatic Cancer Stem Cells.

Cell Metab 2015 Oct 10;22(4):590-605. Epub 2015 Sep 10.

Centre for Stem Cells in Cancer & Ageing, Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK; Stem Cells & Cancer Group, Molecular Pathology Programme, Spanish National Cancer Research Centre (CNIO), Madrid 28029, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2015.08.015DOI Listing
October 2015

The pluripotency factor NANOG promotes the formation of squamous cell carcinomas.

Sci Rep 2015 May 19;5:10205. Epub 2015 May 19.

1] Molecular Oncology Unit, CIEMAT, Madrid 28040, Spain [2] Oncogenomic Unit, Institute of Biomedical Research, University Hospital "12 de Octubre", Madrid 28040, Spain.

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http://dx.doi.org/10.1038/srep10205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437308PMC
May 2015

The contribution of cohesin-SA1 to gene expression and chromatin architecture in two murine tissues.

Nucleic Acids Res 2015 Mar 3;43(6):3056-67. Epub 2015 Mar 3.

Chromosome Dynamics Group, Molecular Oncology Programme, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain

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http://dx.doi.org/10.1093/nar/gkv144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381060PMC
March 2015

Inhibition of de novo NAD(+) synthesis by oncogenic URI causes liver tumorigenesis through DNA damage.

Cancer Cell 2014 Dec 20;26(6):826-839. Epub 2014 Nov 20.

Growth Factors, Nutrients and Cancer Group, BBVA Foundation-Cancer Cell Biology Programme, Spanish National Cancer Research Centre, CNIO, 28029 Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2014.10.002DOI Listing
December 2014

Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes.

Nat Commun 2014 Sep 3;5:4723. Epub 2014 Sep 3.

Telomeres and Telomerase Group, Spanish National Cancer Research Centre (CNIO), C/Melchor Fernández Almagro, 3, 28029 Madrid, Spain.

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http://www.nature.com/articles/ncomms5723
Publisher Site
http://dx.doi.org/10.1038/ncomms5723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164772PMC
September 2014

Reprogramming in vivo produces teratomas and iPS cells with totipotency features.

Nature 2013 Oct 11;502(7471):340-5. Epub 2013 Sep 11.

Tumour Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid E-28029, Spain.

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http://dx.doi.org/10.1038/nature12586DOI Listing
October 2013

The REGIA database (RegiaDB): status, limitations and future developments.

Comp Funct Genomics 2002 ;3(2):109-14

Protein Design Group, National Center for Biotechnology, CNB-CSIC Cantoblanco, Madrid E-28049, Spain.

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http://dx.doi.org/10.1002/cfg.144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2447265PMC
June 2010

MidA is a putative methyltransferase that is required for mitochondrial complex I function.

J Cell Sci 2010 May 20;123(Pt 10):1674-83. Epub 2010 Apr 20.

Instituto de Investigaciones Biomédicas Alberto Sols (CSIC-UAM), Arturo Duperier 4, 28029 Madrid, Spain.

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http://dx.doi.org/10.1242/jcs.066076DOI Listing
May 2010

Assessment of domain boundary predictions and the prediction of intramolecular contacts in CASP8.

Proteins 2009 ;77 Suppl 9:196-209

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre (CNIO), Madrid, Spain.

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http://dx.doi.org/10.1002/prot.22554DOI Listing
January 2010

Assessment of intramolecular contact predictions for CASP7.

Proteins 2007 ;69 Suppl 8:152-8

Structural Biology and Biocomputing Programme, Spanish National Cancer Research Centre, 3E-28029 Madrid, Spain.

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http://dx.doi.org/10.1002/prot.21637DOI Listing
January 2008

Assessment of predictions submitted for the CASP6 comparative modeling category.

Proteins 2005 ;61 Suppl 7:27-45

Protein Design Group, CNB-CSIC, Cantoblanco, Madrid, Spain.

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http://dx.doi.org/10.1002/prot.20720DOI Listing
May 2006

CASP6 assessment of contact prediction.

Proteins 2005 ;61 Suppl 7:214-24

Protein Design Group, Centro Nacional de Biotecnologia (CNB-CSIC), C/Darwin 3, Cantoblanco, Madrid, Spain.

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http://dx.doi.org/10.1002/prot.20739DOI Listing
May 2006

Scoring docking models with evolutionary information.

Proteins 2005 Aug;60(2):275-80

Protein Design Group, CNB-CSIC, Cantoblanco, Madrid, Spain.

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http://dx.doi.org/10.1002/prot.20570DOI Listing
August 2005

EVAcon: a protein contact prediction evaluation service.

Nucleic Acids Res 2005 Jul;33(Web Server issue):W347-51

Protein Design Group, Centro Nacional de Biotecnologia (CNB-CSIC) Cantoblanco, 28049 Madrid, Spain.

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http://dx.doi.org/10.1093/nar/gki411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1160172PMC
July 2005

SQUARE--determining reliable regions in sequence alignments.

Bioinformatics 2004 Apr 5;20(6):974-5. Epub 2004 Feb 5.

CNB-CSIC, Calle Darwin, Cantoblanco, 28049 Madrid, Spain.

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http://dx.doi.org/10.1093/bioinformatics/bth032DOI Listing
April 2004

CAFASP3 in the spotlight of EVA.

Proteins 2003 ;53 Suppl 6:548-60

CUBIC, Department of Biochemistry and Molecular Biophysics, Columbia University, New York, New York 10032, USA.

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http://dx.doi.org/10.1002/prot.10534DOI Listing
January 2004

EVA: Evaluation of protein structure prediction servers.

Nucleic Acids Res 2003 Jul;31(13):3311-5

Columbia University Center for Computational Biology and Bioinformatics (C2B2), Russ Berrie Pavilion, 1150 St Nicholas Avenue, New York, NY 10032, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC169025PMC
http://dx.doi.org/10.1093/nar/gkg619DOI Listing
July 2003